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The map label for this gene is lvhB11 [H]

Identifier: 54293122

GI number: 54293122

Start: 191181

End: 192185

Strand: Direct

Name: lvhB11 [H]

Synonym: lpl0161

Alternate gene names: 54293122

Gene position: 191181-192185 (Clockwise)

Preceding gene: 54293121

Following gene: 54293123

Centisome position: 5.71

GC content: 44.18

Gene sequence:

>1005_bases
ATGGAAGCTATTAAAGCCTGCTTCTCGCCCGGCGCAACAGGTCTGCTCTCGCCATTGCAGGATTTTCTGGAAGATGAGCA
CGTCTCTGAAATTTTAATCAATAAGCCTCAAGAGGTTTTTATCGAGCGACACGGGCAATTAATTCGATTTGATATTCCGG
TATTAACCACCCAATACCTGCGCCGTTTGTTTTTACTGATTGCCAATGAAAATAAGCAAACGCTCTCGGAATCCTCGCCC
GTGCTTTCTGGGAATCTGGCTGATGGCTCAAGGGTTCAACTGGTGATGCCACCAGCCTCCCTACATGAAACACTATCCAT
CCGAAAATTTACTTTAAAACAGGTTAGCTTCGAAGATTACAAAGCCAAAGGATTTTTTTCATCGGCGCGTGGGGTAGGAG
TTAAAGAGTACTCGGAGTGCATTGGTAAAACCGATGGGCTGCTTGAACTCTACGATGCTAAAAACTGGCAGGAATTTATA
AGACAAGCCATTATGAGTAAGAAAAACATCATCATATCGGGTGGAACCTCTTCAGGTAAAACGACTTTTTTAAACAGTTG
TGTAGGGCAAATACCGCTTCATGAACGCCTCATTACACTTGAGGATACTTATGAAATGGATGTACCCCACAGCAATATTG
TTCGTCTGAAAGCATTAAAGCAAATCGGGGATCACGCACAGAAGATCACCATGCAGGATTTGGTTCAAGCCACCTTAAGA
CTCAGACCCGACCGCATTATTATGGGTGAAATTCGCGGGCGAGAACTCTTTGATTTTGTATCAGCCTGTTCCACGGGGCA
TAGCGGTGCACTTGCAACCATCCATGCCAATAACCCAAAAGTTGCTTTTATGCGTATGGCGCAACTCTACAAACTGAATC
AGGTTGCAGGCATGGATGAGGCTGATATTTACAAAGTGTTGCATGAAGTCATTGATGTCATCGTCCAGTTACAAAAAACA
TCAGACGGCAGGCGATTAGTGGAGGTCTATTATAAACATGCGTAA

Upstream 100 bases:

>100_bases
ATGCAAACACGCCCGACTTTGCAAATCAATCAGGGAGCTGCCATTAACGTATTTGTAGCTCACGATCTTGATTTCTACCG
AGTGGCTGGGAGGGCATAAT

Downstream 100 bases:

>100_bases
TCCACGGGTTATTGCAGTCGCCTTAATCATCGGGCTTGCCATAACCGCCCAAATTGCAGTGCTGTTGACAGGTATCACCC
AGTGGTCAAGTCCATTGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MEAIKACFSPGATGLLSPLQDFLEDEHVSEILINKPQEVFIERHGQLIRFDIPVLTTQYLRRLFLLIANENKQTLSESSP
VLSGNLADGSRVQLVMPPASLHETLSIRKFTLKQVSFEDYKAKGFFSSARGVGVKEYSECIGKTDGLLELYDAKNWQEFI
RQAIMSKKNIIISGGTSSGKTTFLNSCVGQIPLHERLITLEDTYEMDVPHSNIVRLKALKQIGDHAQKITMQDLVQATLR
LRPDRIIMGEIRGRELFDFVSACSTGHSGALATIHANNPKVAFMRMAQLYKLNQVAGMDEADIYKVLHEVIDVIVQLQKT
SDGRRLVEVYYKHA

Sequences:

>Translated_334_residues
MEAIKACFSPGATGLLSPLQDFLEDEHVSEILINKPQEVFIERHGQLIRFDIPVLTTQYLRRLFLLIANENKQTLSESSP
VLSGNLADGSRVQLVMPPASLHETLSIRKFTLKQVSFEDYKAKGFFSSARGVGVKEYSECIGKTDGLLELYDAKNWQEFI
RQAIMSKKNIIISGGTSSGKTTFLNSCVGQIPLHERLITLEDTYEMDVPHSNIVRLKALKQIGDHAQKITMQDLVQATLR
LRPDRIIMGEIRGRELFDFVSACSTGHSGALATIHANNPKVAFMRMAQLYKLNQVAGMDEADIYKVLHEVIDVIVQLQKT
SDGRRLVEVYYKHA
>Mature_334_residues
MEAIKACFSPGATGLLSPLQDFLEDEHVSEILINKPQEVFIERHGQLIRFDIPVLTTQYLRRLFLLIANENKQTLSESSP
VLSGNLADGSRVQLVMPPASLHETLSIRKFTLKQVSFEDYKAKGFFSSARGVGVKEYSECIGKTDGLLELYDAKNWQEFI
RQAIMSKKNIIISGGTSSGKTTFLNSCVGQIPLHERLITLEDTYEMDVPHSNIVRLKALKQIGDHAQKITMQDLVQATLR
LRPDRIIMGEIRGRELFDFVSACSTGHSGALATIHANNPKVAFMRMAQLYKLNQVAGMDEADIYKVLHEVIDVIVQLQKT
SDGRRLVEVYYKHA

Specific function: The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a proinflammatory activation by nuclear factor NF-

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cell inner membrane (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014155
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 37509; Mature: 37509

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIKACFSPGATGLLSPLQDFLEDEHVSEILINKPQEVFIERHGQLIRFDIPVLTTQYL
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEECHHHHHHHH
RRLFLLIANENKQTLSESSPVLSGNLADGSRVQLVMPPASLHETLSIRKFTLKQVSFEDY
HHHHHHHCCCCHHHHHHCCCEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHH
KAKGFFSSARGVGVKEYSECIGKTDGLLELYDAKNWQEFIRQAIMSKKNIIISGGTSSGK
HCCCCHHHHCCCCHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCC
TTFLNSCVGQIPLHERLITLEDTYEMDVPHSNIVRLKALKQIGDHAQKITMQDLVQATLR
HHHHHHHHHCCCHHHEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPDRIIMGEIRGRELFDFVSACSTGHSGALATIHANNPKVAFMRMAQLYKLNQVAGMDE
CCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCH
ADIYKVLHEVIDVIVQLQKTSDGRRLVEVYYKHA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MEAIKACFSPGATGLLSPLQDFLEDEHVSEILINKPQEVFIERHGQLIRFDIPVLTTQYL
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEECHHHHHHHH
RRLFLLIANENKQTLSESSPVLSGNLADGSRVQLVMPPASLHETLSIRKFTLKQVSFEDY
HHHHHHHCCCCHHHHHHCCCEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHH
KAKGFFSSARGVGVKEYSECIGKTDGLLELYDAKNWQEFIRQAIMSKKNIIISGGTSSGK
HCCCCHHHHCCCCHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCC
TTFLNSCVGQIPLHERLITLEDTYEMDVPHSNIVRLKALKQIGDHAQKITMQDLVQATLR
HHHHHHHHHCCCHHHEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPDRIIMGEIRGRELFDFVSACSTGHSGALATIHANNPKVAFMRMAQLYKLNQVAGMDE
CCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCH
ADIYKVLHEVIDVIVQLQKTSDGRRLVEVYYKHA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10882236 [H]