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The map label for this gene is tap [H]

Identifier: 54027482

GI number: 54027482

Start: 5836303

End: 5837871

Strand: Reverse

Name: tap [H]

Synonym: nfa55080

Alternate gene names: 54027482

Gene position: 5837871-5836303 (Counterclockwise)

Preceding gene: 54027484

Following gene: 54027481

Centisome position: 96.95

GC content: 73.1

Gene sequence:

>1569_bases
ATGATGAGAACACGGCTGTTCCGGGCGGTTTCGGCGCTGACCGCGGTGGGCGCCGTCGGTGCGTCGCTGCTCTGCGCAGC
CGCGACCGCCGCGCCGGGACCGGTGTTCGGGGACTGCCCCGAGGGCGCGGTCACGCCCGGCGTCGGGGTGCGCTGCGCGG
TGGTGAGCGTGCCGATGAACCATGCCGAACCCGACGGTCCCCGAATCGAACTCACCGTCAGCCGCATCGCCGCCTCGGGC
GAGCGCCGCGGCGCGCTGTTCACCAACCCCGGTGGCCCGGGTGTCGACGCGCTCGACTTCTGGGCGCAGCGGCTGTCCAC
CGTGCCCGCCGAACTCGTCGAGCACTACGACCTGCTGGCCGTGCAGCCGCGCGGGCTGCGCTGGGCCACGCCGTTGGCCT
GCGCGGTGGATGCGGCCGCGCCCGGCCAGGTCTCCACCACCGACGAGGAACTGAAGCGGGCCTGCGACGCCGCCCAGCCC
GGCTACCTCGACACCATCACCACCGAGAACACCGCGCGCGACCTGGATGCGGTGCGCGCCGCGCTCGGCCTCGACCGGAT
CGACTACCTGGGCACCTCCTACGGCACCTACCTGGGCGCGGTGTACGCCACGCTGTTCCCGGATCGGGTCGGCCGCATGG
TGCTCGACTCCAACGTGCACCCGGGCTGGATCTGGACCGAGGAATTCGCCCAGCAGCAGGCCGCGGGCAAGCAGCGCATG
GACGACCTGTTCGGCTGGATCGCCGAACGCGACGCCGAATACCACCTGGGCAGTACGCCGTTGCAGGTCTACCGCACCTG
GGTGCGGCTGGTCTCGGCGCAGGGCGGCGGCTGGTACGCCAACCTCACCCCGCCGCCCGCGAGCGTCGCCGACTTGCCGG
GCGATCTGCCCGAGCCGCTGGCCGAGATCGCCCGCGACGGTGTCAACGGCACGGTCGAGCACCTGGTGAAGGTGCAGAAC
TTCCTGCGCACCTTGGTGTCCGGCGGCGCCTCGGCCCAGGTACCGCTGATCGGGGCGACGTCGGTGGCCACCTACACCCG
GGCGTTCTGGCCGACCTTCGCCGAGGCGATGGCCGCCGCGAACGCCGACCCGGCGAACGTGGCCCGGCTGCGCGCCATCG
CCGGCGCGACCGCGACCGATCCCACCGGGCGTTTCGTGTTCTCCGCCATCACCTGCAACGAGAACGCCGTACCCGGCAGG
CCGGAGCTGCTCGGCGCGGCGGTGGGCACCATCGCCTCGGGCGGCAACGCCTTGGACGCGCGCGCCGATCTGGTGCGTTC
CGGGATGAGTTGCGGTACCTGGAAGCCGGTCACCACGCCGGTGCCGATCGACGGCTCGGGCCTGGCGACCAGGCCGCTGC
TGCTGCAGAGCCGCAACGACGCGCTCACCCGCTACGAGGGCGGACCGGCGATGGCGCGGGCGCTCGGCGGCGCCCTGGTC
ACCGTCGAGGGCGGTGACCACGGCACCTTCGGGCGCGGCAACCCGGCCGTCGACGAGGCCGTGCTCACCTATCTCCGCAC
CGGTGAGGTCAACGCGACCGTGCTCCCCGAGGCACCGCTGCCCGGCTGA

Upstream 100 bases:

>100_bases
ACACGAGACATCGCGACGCGCACGAGTGGGAAATCTCCCGGTCGACTTGTCTGCGCGTGCCGGGCCGATCAGAATGCTCT
GTGGCCGAGAGGTACGAAAG

Downstream 100 bases:

>100_bases
GCCGCCCGCCTCGGCGAAATTCCCCCCGGCGGTCGAGAATGGCTTGATGACCGCCGTGCCCCGGGTGCTGCTCGCCCCGG
ACAAGTTCAAGGGCTCGCTG

Product: putative hydrolase

Products: NA

Alternate protein names: Tap [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MMRTRLFRAVSALTAVGAVGASLLCAAATAAPGPVFGDCPEGAVTPGVGVRCAVVSVPMNHAEPDGPRIELTVSRIAASG
ERRGALFTNPGGPGVDALDFWAQRLSTVPAELVEHYDLLAVQPRGLRWATPLACAVDAAAPGQVSTTDEELKRACDAAQP
GYLDTITTENTARDLDAVRAALGLDRIDYLGTSYGTYLGAVYATLFPDRVGRMVLDSNVHPGWIWTEEFAQQQAAGKQRM
DDLFGWIAERDAEYHLGSTPLQVYRTWVRLVSAQGGGWYANLTPPPASVADLPGDLPEPLAEIARDGVNGTVEHLVKVQN
FLRTLVSGGASAQVPLIGATSVATYTRAFWPTFAEAMAAANADPANVARLRAIAGATATDPTGRFVFSAITCNENAVPGR
PELLGAAVGTIASGGNALDARADLVRSGMSCGTWKPVTTPVPIDGSGLATRPLLLQSRNDALTRYEGGPAMARALGGALV
TVEGGDHGTFGRGNPAVDEAVLTYLRTGEVNATVLPEAPLPG

Sequences:

>Translated_522_residues
MMRTRLFRAVSALTAVGAVGASLLCAAATAAPGPVFGDCPEGAVTPGVGVRCAVVSVPMNHAEPDGPRIELTVSRIAASG
ERRGALFTNPGGPGVDALDFWAQRLSTVPAELVEHYDLLAVQPRGLRWATPLACAVDAAAPGQVSTTDEELKRACDAAQP
GYLDTITTENTARDLDAVRAALGLDRIDYLGTSYGTYLGAVYATLFPDRVGRMVLDSNVHPGWIWTEEFAQQQAAGKQRM
DDLFGWIAERDAEYHLGSTPLQVYRTWVRLVSAQGGGWYANLTPPPASVADLPGDLPEPLAEIARDGVNGTVEHLVKVQN
FLRTLVSGGASAQVPLIGATSVATYTRAFWPTFAEAMAAANADPANVARLRAIAGATATDPTGRFVFSAITCNENAVPGR
PELLGAAVGTIASGGNALDARADLVRSGMSCGTWKPVTTPVPIDGSGLATRPLLLQSRNDALTRYEGGPAMARALGGALV
TVEGGDHGTFGRGNPAVDEAVLTYLRTGEVNATVLPEAPLPG
>Mature_522_residues
MMRTRLFRAVSALTAVGAVGASLLCAAATAAPGPVFGDCPEGAVTPGVGVRCAVVSVPMNHAEPDGPRIELTVSRIAASG
ERRGALFTNPGGPGVDALDFWAQRLSTVPAELVEHYDLLAVQPRGLRWATPLACAVDAAAPGQVSTTDEELKRACDAAQP
GYLDTITTENTARDLDAVRAALGLDRIDYLGTSYGTYLGAVYATLFPDRVGRMVLDSNVHPGWIWTEEFAQQQAAGKQRM
DDLFGWIAERDAEYHLGSTPLQVYRTWVRLVSAQGGGWYANLTPPPASVADLPGDLPEPLAEIARDGVNGTVEHLVKVQN
FLRTLVSGGASAQVPLIGATSVATYTRAFWPTFAEAMAAANADPANVARLRAIAGATATDPTGRFVFSAITCNENAVPGR
PELLGAAVGTIASGGNALDARADLVRSGMSCGTWKPVTTPVPIDGSGLATRPLLLQSRNDALTRYEGGPAMARALGGALV
TVEGGDHGTFGRGNPAVDEAVLTYLRTGEVNATVLPEAPLPG

Specific function: Cleaves tripeptides from the N-termini of proteins. Does not cleave mono- or dipeptides, or N-terminally blocked peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013595 [H]

Pfam domain/function: PF08386 Abhydrolase_4 [H]

EC number: NA

Molecular weight: Translated: 54403; Mature: 54403

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTRLFRAVSALTAVGAVGASLLCAAATAAPGPVFGDCPEGAVTPGVGVRCAVVSVPMN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
HAEPDGPRIELTVSRIAASGERRGALFTNPGGPGVDALDFWAQRLSTVPAELVEHYDLLA
CCCCCCCEEEEEHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHCCEEE
VQPRGLRWATPLACAVDAAAPGQVSTTDEELKRACDAAQPGYLDTITTENTARDLDAVRA
ECCCCCEECCCHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHH
ALGLDRIDYLGTSYGTYLGAVYATLFPDRVGRMVLDSNVHPGWIWTEEFAQQQAAGKQRM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEHHHHHHHHHHHHHHH
DDLFGWIAERDAEYHLGSTPLQVYRTWVRLVSAQGGGWYANLTPPPASVADLPGDLPEPL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHCCCCCCHHHH
AEIARDGVNGTVEHLVKVQNFLRTLVSGGASAQVPLIGATSVATYTRAFWPTFAEAMAAA
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHC
NADPANVARLRAIAGATATDPTGRFVFSAITCNENAVPGRPELLGAAVGTIASGGNALDA
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHH
RADLVRSGMSCGTWKPVTTPVPIDGSGLATRPLLLQSRNDALTRYEGGPAMARALGGALV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCCHHHHHHHCCEEE
TVEGGDHGTFGRGNPAVDEAVLTYLRTGEVNATVLPEAPLPG
EEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCC
>Mature Secondary Structure
MMRTRLFRAVSALTAVGAVGASLLCAAATAAPGPVFGDCPEGAVTPGVGVRCAVVSVPMN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
HAEPDGPRIELTVSRIAASGERRGALFTNPGGPGVDALDFWAQRLSTVPAELVEHYDLLA
CCCCCCCEEEEEHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCHHHHHHHCCEEE
VQPRGLRWATPLACAVDAAAPGQVSTTDEELKRACDAAQPGYLDTITTENTARDLDAVRA
ECCCCCEECCCHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHH
ALGLDRIDYLGTSYGTYLGAVYATLFPDRVGRMVLDSNVHPGWIWTEEFAQQQAAGKQRM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEHHHHHHHHHHHHHHH
DDLFGWIAERDAEYHLGSTPLQVYRTWVRLVSAQGGGWYANLTPPPASVADLPGDLPEPL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHCCCCCCHHHH
AEIARDGVNGTVEHLVKVQNFLRTLVSGGASAQVPLIGATSVATYTRAFWPTFAEAMAAA
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHC
NADPANVARLRAIAGATATDPTGRFVFSAITCNENAVPGRPELLGAAVGTIASGGNALDA
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHH
RADLVRSGMSCGTWKPVTTPVPIDGSGLATRPLLLQSRNDALTRYEGGPAMARALGGALV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCCHHHHHHHCCEEE
TVEGGDHGTFGRGNPAVDEAVLTYLRTGEVNATVLPEAPLPG
EEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]