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The map label for this gene is fadE48 [H]

Identifier: 54027410

GI number: 54027410

Start: 5755559

End: 5756767

Strand: Reverse

Name: fadE48 [H]

Synonym: nfa54360

Alternate gene names: 54027410

Gene position: 5756767-5755559 (Counterclockwise)

Preceding gene: 54027411

Following gene: 54027408

Centisome position: 95.61

GC content: 72.29

Gene sequence:

>1209_bases
ATGACATCCATCGAAGCGACAACCACGTCCGATGCCGAGTTGGACGAGATCTTCCAGCCGATCTTCCGGCGCATCGCCGA
GGGGGCGGTGGCGCGCGAGGTCGATCGGCGGCTGGCGTACGAGGAGGTCGACCTGCTCCGGCAGGCCCGGTTCGGGGCGC
TGCGGGTGCCGGTCGAGTTCGGCGGCTACGGCGCGAGCGTGTGGCAGCTGTTCCGGCTGCTGATCGACCTCGCGGCGGCG
GAATCGAATCTGCCGCAGGCGCTGCGGGTGCACTTCTCCTTCGTGGAGGACCAACTGCTGGCCGAGCCGGGCCCGCAGCG
CGAGCGGTGGTTGCGCGCGGTCGCCGACGGCACGCTGGTCGGCAACGCCATCACCGAGCCGGGGGTGGGCGCGGTGGACC
GCTACCGCACGACGCTGACCCGCGCCGGCGACCGCTGGCTGCTCAACGGCACCAAGTACTACAGCACCGGCTCGCTCTAC
GCCGACCACATCCTGGTCGCCGCCGACCGTGACGGCGAGCGGGTGAGCGTGCTGGTGGACGCCGACGCCGACGGAGTACG
CCAGCACGACGACTGGGACGGTTTCGGCCAGCGCCTCACCGCGAGCGGCACCACCGAGTTCACCGACGTCGTGGTGCCGG
AGGAGCGCGTGCTCGGCCCCGGCTACGGCGCTCCCGGACCCACCTACGCCACCGGCTACCTGCAGCTCGTGCAACTGGCT
GTGCTGGCCGGCATCGCCGCCAGGGCCGAGGCCGACGCCCGCGACTGGGTCGCCCGCCGCACCCGCGGCTACACCCACTC
GGCCGCCGACCTGCCCCGCCACGACCCGCTCGTGCAGCAGGTGATCGGCAAGCTCTCCGCCGCCGCGTTCACCGCCCGCG
CCACGGTGCTGGCCGTCGCGGATCGTCTCGACTCGGTGCTGGCCGCGGGCGCGCGCGACGAGGACGACCTGGTGTCGGTC
GAATTGGCCGCCGCGCAAGCGCAATTGGGTGTGATCGACGTGGTGCTGCCCGCCACCAGCCTGCTGTTCGAGGTCGGCGG
TGCCTCCATCGTCGCCGAGGAACTGCGGCTGGATCGGCACTGGCGCAACGCGCGCACCATCTCCGTGCACAACCCGGCCA
TCCAGAAGGCGCGCGCCATCGGCGACCACCTGCTCAACGGCGCCGACCTGCCCTTCGCCTGGAGCGCGGGCGAACGCAAG
TCCGCCTGA

Upstream 100 bases:

>100_bases
CACCCGGCCGGTATGCCCTGGCCCGTACGACACCGCCCGTATTCGGATCGCGGTGCGCGGAACCGGTGAACCCGCCGCCG
TTGCCGGTCATCGTTGGCGG

Downstream 100 bases:

>100_bases
TCGGAGGGCGCCGCCCGGTCAGCGAGCGCCTCCTGGTCAACGAGCGCCGTCTGATCAGCGAGCGCCTCCTGGTCAACGAG
CGTTGCCTGGTCAGAGAGCG

Product: putative acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: DBT sulfur dioxygenase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTSIEATTTSDAELDEIFQPIFRRIAEGAVAREVDRRLAYEEVDLLRQARFGALRVPVEFGGYGASVWQLFRLLIDLAAA
ESNLPQALRVHFSFVEDQLLAEPGPQRERWLRAVADGTLVGNAITEPGVGAVDRYRTTLTRAGDRWLLNGTKYYSTGSLY
ADHILVAADRDGERVSVLVDADADGVRQHDDWDGFGQRLTASGTTEFTDVVVPEERVLGPGYGAPGPTYATGYLQLVQLA
VLAGIAARAEADARDWVARRTRGYTHSAADLPRHDPLVQQVIGKLSAAAFTARATVLAVADRLDSVLAAGARDEDDLVSV
ELAAAQAQLGVIDVVLPATSLLFEVGGASIVAEELRLDRHWRNARTISVHNPAIQKARAIGDHLLNGADLPFAWSAGERK
SA

Sequences:

>Translated_402_residues
MTSIEATTTSDAELDEIFQPIFRRIAEGAVAREVDRRLAYEEVDLLRQARFGALRVPVEFGGYGASVWQLFRLLIDLAAA
ESNLPQALRVHFSFVEDQLLAEPGPQRERWLRAVADGTLVGNAITEPGVGAVDRYRTTLTRAGDRWLLNGTKYYSTGSLY
ADHILVAADRDGERVSVLVDADADGVRQHDDWDGFGQRLTASGTTEFTDVVVPEERVLGPGYGAPGPTYATGYLQLVQLA
VLAGIAARAEADARDWVARRTRGYTHSAADLPRHDPLVQQVIGKLSAAAFTARATVLAVADRLDSVLAAGARDEDDLVSV
ELAAAQAQLGVIDVVLPATSLLFEVGGASIVAEELRLDRHWRNARTISVHNPAIQKARAIGDHLLNGADLPFAWSAGERK
SA
>Mature_401_residues
TSIEATTTSDAELDEIFQPIFRRIAEGAVAREVDRRLAYEEVDLLRQARFGALRVPVEFGGYGASVWQLFRLLIDLAAAE
SNLPQALRVHFSFVEDQLLAEPGPQRERWLRAVADGTLVGNAITEPGVGAVDRYRTTLTRAGDRWLLNGTKYYSTGSLYA
DHILVAADRDGERVSVLVDADADGVRQHDDWDGFGQRLTASGTTEFTDVVVPEERVLGPGYGAPGPTYATGYLQLVQLAV
LAGIAARAEADARDWVARRTRGYTHSAADLPRHDPLVQQVIGKLSAAAFTARATVLAVADRLDSVLAAGARDEDDLVSVE
LAAAQAQLGVIDVVLPATSLLFEVGGASIVAEELRLDRHWRNARTISVHNPAIQKARAIGDHLLNGADLPFAWSAGERKS
A

Specific function: Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Sulfur dioxygenase which converts DBT to DBT-sulfone (DBTO2 or DBT 5,5-dioxide) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17569725, Length=194, Percent_Identity=25.7731958762887, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43498; Mature: 43367

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIEATTTSDAELDEIFQPIFRRIAEGAVAREVDRRLAYEEVDLLRQARFGALRVPVEF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHEE
GGYGASVWQLFRLLIDLAAAESNLPQALRVHFSFVEDQLLAEPGPQRERWLRAVADGTLV
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEE
GNAITEPGVGAVDRYRTTLTRAGDRWLLNGTKYYSTGSLYADHILVAADRDGERVSVLVD
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCEEECEEEEEECCCCCEEEEEEE
ADADGVRQHDDWDGFGQRLTASGTTEFTDVVVPEERVLGPGYGAPGPTYATGYLQLVQLA
CCCCCCCCCCCCCCCCCEEECCCCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHH
VLAGIAARAEADARDWVARRTRGYTHSAADLPRHDPLVQQVIGKLSAAAFTARATVLAVA
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRLDSVLAAGARDEDDLVSVELAAAQAQLGVIDVVLPATSLLFEVGGASIVAEELRLDRH
HHHHHHHHCCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WRNARTISVHNPAIQKARAIGDHLLNGADLPFAWSAGERKSA
HCCCCEEEECCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TSIEATTTSDAELDEIFQPIFRRIAEGAVAREVDRRLAYEEVDLLRQARFGALRVPVEF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHEE
GGYGASVWQLFRLLIDLAAAESNLPQALRVHFSFVEDQLLAEPGPQRERWLRAVADGTLV
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEE
GNAITEPGVGAVDRYRTTLTRAGDRWLLNGTKYYSTGSLYADHILVAADRDGERVSVLVD
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCEEECEEEEEECCCCCEEEEEEE
ADADGVRQHDDWDGFGQRLTASGTTEFTDVVVPEERVLGPGYGAPGPTYATGYLQLVQLA
CCCCCCCCCCCCCCCCCEEECCCCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHH
VLAGIAARAEADARDWVARRTRGYTHSAADLPRHDPLVQQVIGKLSAAAFTARATVLAVA
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRLDSVLAAGARDEDDLVSVELAAAQAQLGVIDVVLPATSLLFEVGGASIVAEELRLDRH
HHHHHHHHCCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WRNARTISVHNPAIQKARAIGDHLLNGADLPFAWSAGERKSA
HCCCCEEEECCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961424; 7574582 [H]