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The map label for this gene is fadE46 [H]

Identifier: 54027395

GI number: 54027395

Start: 5736892

End: 5738034

Strand: Reverse

Name: fadE46 [H]

Synonym: nfa54210

Alternate gene names: 54027395

Gene position: 5738034-5736892 (Counterclockwise)

Preceding gene: 54027396

Following gene: 54027393

Centisome position: 95.3

GC content: 71.74

Gene sequence:

>1143_bases
ATGGACTTCACACTCACCGAGGAGCAGCAGCTCCTGCGCGACACCGTCGCCGGCTTCCTCGCCGCCCGGTACGACCTCGA
GAAGAGCCGCGCCGCGGTGAAGTCGGGTGAGGGCTGGCAGCCCGCCGTGTGGCGCGGGTTCGCCGAAGAACTCGGCATTC
TCGGCGCCACCCTGCCCGAGCGGGTCGACGGCATGGGCGGCGGCGCGGCCGAACTGCTCGTCATCGCCGAGGAATTGGGC
CGGGCCCTGGTCGTGGAACCGTTCGTCGACACCGTGGTGATCGGCGCCGGCCTGCTCGACCGGGCGGGCGGTTCGGAGGA
TCTGTTGCGCGGCATCGTCGCGGGCGAGGTGCGCACCGCCTTCGCCGCGACCGAACCGACCTCCGGGCACAGCCTCTGCG
ATGTGCGCACCACCGCCCGCCGCGACGGTGACGGCTGGGTGCTCGACGGCACGAAGGTGGTCGTCACCAGCGCGCCGCTG
GCCACGCACCTGATCATCACCGCGCGCACCGCGGGCGAGCACCGCGACCGGGACGGCATCTCGCTGTTCTGCGTGCCGTT
CGATCCGCAGCACCCGCCCGCGGGTGTCGAATACCACCCGTACCGCACCATCGACGACCGCCAGGCCGCGGATCTGGTCT
TCACCGGCTACCGGGTGCCCGCCGCCGCCCTGCTCGGCGCCGAGGGCGATGCCTGGGCGGCGATCGAACCGACCGTCGAC
ACCGCGCTCGCCGCGATCTGCGCCGAAGCCGTCGGCTGCCTGCGCAAGGTGTTCACCGACACCGTCGCCTACAGCAAGCA
GCGCCAGCAGTTCGGCGTCCCGATCGGCAGCTTCCAGGCCCTGCAACACCGCATGGTCGACATGTACATGGAACTCGAAC
AGGCCGCCGCCGCGGCCCAACTCGCGGGCGCGGCCCTGTCCGCCGCTCCGGCCGAACGCAGCCGCGCCATCGCCGCCGCC
AAGGTCACCGTCGGCCGGGCGGCCCGTTTCATCGGCCAGAACGCCGTCCAGCTGCACGGCGCCATGGGCATGACCGAGGA
GCTGGCCATCGGCCACTACTTCAAGCGCTTGACCGTGCTTGAAAGGGAATTCGGCACCGTGGACCACCACCGCGCCCGAT
ACGCGGCCCTGACCCGGCCGTAG

Upstream 100 bases:

>100_bases
TCGCGCCGCTGCGCTACTTCAACGACCGCGCGGGCTCGATCTACGCGGGCAGCAACGAAATTCAGCGAAACATCCTCGCC
AAGGCAGCATTGGGGCTCTG

Downstream 100 bases:

>100_bases
CACCCCGCGCCCCCCCCGCCCGGAACCGCCCAGGTTCCGGGCTACAGGCGCATCCCTGTCCGGCACGCGCCGTGCCCTCG
GCTGCCCCGGTACGGCGGCG

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDFTLTEEQQLLRDTVAGFLAARYDLEKSRAAVKSGEGWQPAVWRGFAEELGILGATLPERVDGMGGGAAELLVIAEELG
RALVVEPFVDTVVIGAGLLDRAGGSEDLLRGIVAGEVRTAFAATEPTSGHSLCDVRTTARRDGDGWVLDGTKVVVTSAPL
ATHLIITARTAGEHRDRDGISLFCVPFDPQHPPAGVEYHPYRTIDDRQAADLVFTGYRVPAAALLGAEGDAWAAIEPTVD
TALAAICAEAVGCLRKVFTDTVAYSKQRQQFGVPIGSFQALQHRMVDMYMELEQAAAAAQLAGAALSAAPAERSRAIAAA
KVTVGRAARFIGQNAVQLHGAMGMTEELAIGHYFKRLTVLEREFGTVDHHRARYAALTRP

Sequences:

>Translated_380_residues
MDFTLTEEQQLLRDTVAGFLAARYDLEKSRAAVKSGEGWQPAVWRGFAEELGILGATLPERVDGMGGGAAELLVIAEELG
RALVVEPFVDTVVIGAGLLDRAGGSEDLLRGIVAGEVRTAFAATEPTSGHSLCDVRTTARRDGDGWVLDGTKVVVTSAPL
ATHLIITARTAGEHRDRDGISLFCVPFDPQHPPAGVEYHPYRTIDDRQAADLVFTGYRVPAAALLGAEGDAWAAIEPTVD
TALAAICAEAVGCLRKVFTDTVAYSKQRQQFGVPIGSFQALQHRMVDMYMELEQAAAAAQLAGAALSAAPAERSRAIAAA
KVTVGRAARFIGQNAVQLHGAMGMTEELAIGHYFKRLTVLEREFGTVDHHRARYAALTRP
>Mature_380_residues
MDFTLTEEQQLLRDTVAGFLAARYDLEKSRAAVKSGEGWQPAVWRGFAEELGILGATLPERVDGMGGGAAELLVIAEELG
RALVVEPFVDTVVIGAGLLDRAGGSEDLLRGIVAGEVRTAFAATEPTSGHSLCDVRTTARRDGDGWVLDGTKVVVTSAPL
ATHLIITARTAGEHRDRDGISLFCVPFDPQHPPAGVEYHPYRTIDDRQAADLVFTGYRVPAAALLGAEGDAWAAIEPTVD
TALAAICAEAVGCLRKVFTDTVAYSKQRQQFGVPIGSFQALQHRMVDMYMELEQAAAAAQLAGAALSAAPAERSRAIAAA
KVTVGRAARFIGQNAVQLHGAMGMTEELAIGHYFKRLTVLEREFGTVDHHRARYAALTRP

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=331, Percent_Identity=27.7945619335347, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4501857, Length=358, Percent_Identity=25.9776536312849, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=26.4248704663212, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI226958414, Length=376, Percent_Identity=26.3297872340426, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=23.6220472440945, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4557235, Length=381, Percent_Identity=23.6220472440945, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=23.8341968911917, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=23.8341968911917, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501859, Length=362, Percent_Identity=24.0331491712707, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=25.2054794520548, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21361497, Length=347, Percent_Identity=24.207492795389, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=362, Percent_Identity=23.2044198895028, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786223, Length=369, Percent_Identity=24.390243902439, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=332, Percent_Identity=25.3012048192771, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=313, Percent_Identity=25.8785942492013, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=23.2804232804233, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=23.8845144356955, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=322, Percent_Identity=27.0186335403727, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=391, Percent_Identity=23.5294117647059, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=325, Percent_Identity=26.1538461538462, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=389, Percent_Identity=24.6786632390745, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=399, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=296, Percent_Identity=25, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=260, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=308, Percent_Identity=22.4025974025974, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=23.5537190082645, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=26.0752688172043, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24666513, Length=371, Percent_Identity=24.7978436657682, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=26.9633507853403, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=25.6476683937824, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363737, Length=394, Percent_Identity=22.8426395939086, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=25.9358288770053, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40560; Mature: 40560

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTLTEEQQLLRDTVAGFLAARYDLEKSRAAVKSGEGWQPAVWRGFAEELGILGATLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
RVDGMGGGAAELLVIAEELGRALVVEPFVDTVVIGAGLLDRAGGSEDLLRGIVAGEVRTA
HHCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHH
FAATEPTSGHSLCDVRTTARRDGDGWVLDGTKVVVTSAPLATHLIITARTAGEHRDRDGI
HCCCCCCCCCCEEEEHHHHCCCCCCEEEECCEEEEECCCHHEEEEEEEECCCCCCCCCCC
SLFCVPFDPQHPPAGVEYHPYRTIDDRQAADLVFTGYRVPAAALLGAEGDAWAAIEPTVD
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCEEEECCHHH
TALAAICAEAVGCLRKVFTDTVAYSKQRQQFGVPIGSFQALQHRMVDMYMELEQAAAAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGAALSAAPAERSRAIAAAKVTVGRAARFIGQNAVQLHGAMGMTEELAIGHYFKRLTVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHCCCCHHHHHHHHHHHHHHHH
EREFGTVDHHRARYAALTRP
HHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MDFTLTEEQQLLRDTVAGFLAARYDLEKSRAAVKSGEGWQPAVWRGFAEELGILGATLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
RVDGMGGGAAELLVIAEELGRALVVEPFVDTVVIGAGLLDRAGGSEDLLRGIVAGEVRTA
HHCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHH
FAATEPTSGHSLCDVRTTARRDGDGWVLDGTKVVVTSAPLATHLIITARTAGEHRDRDGI
HCCCCCCCCCCEEEEHHHHCCCCCCEEEECCEEEEECCCHHEEEEEEEECCCCCCCCCCC
SLFCVPFDPQHPPAGVEYHPYRTIDDRQAADLVFTGYRVPAAALLGAEGDAWAAIEPTVD
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCEEEECCHHH
TALAAICAEAVGCLRKVFTDTVAYSKQRQQFGVPIGSFQALQHRMVDMYMELEQAAAAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGAALSAAPAERSRAIAAAKVTVGRAARFIGQNAVQLHGAMGMTEELAIGHYFKRLTVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHCCCCHHHHHHHHHHHHHHHH
EREFGTVDHHRARYAALTRP
HHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]