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The map label for this gene is yedX [H]

Identifier: 54027217

GI number: 54027217

Start: 5543582

End: 5543911

Strand: Reverse

Name: yedX [H]

Synonym: nfa52430

Alternate gene names: 54027217

Gene position: 5543911-5543582 (Counterclockwise)

Preceding gene: 54027218

Following gene: 54027216

Centisome position: 92.07

GC content: 69.7

Gene sequence:

>330_bases
ATGAGCACACCCGGTACGAGCACACTGAGTACCCACGTGCTGGACGCCGTGCGCGGCGTCCCTGCCGCCGGGGTCGCCGT
CACGCTGTACGCCGGAGCCGAACCGGTCGCCTCGGGCGCGACCGACGCCGACGGGCGCATCGGCGGGCTCGCCGAGGTGT
CGCCGGGGACCTACCGCCTGGTGTTCGACACCGGCGCGTATTTCGCCGCGCAGGGCACACCGACCTTCTACCCGGAGGTC
GCGATCACCTTCGCGGTGACCGAGGAACGTCACCACCACGTGCCGTTGCTGCTGTCGCCCTTCGCTTTTTCCACCTACCG
AGGGAGTTGA

Upstream 100 bases:

>100_bases
ACGACCCGGAAGTCGAAACACGCGTCCTCCGAGAGGAATTGGCGAAGATCAATCGGCTCCGGCTGGGCCGCCTGCCTGCC
GTCACGGGAGAGGACCCGGT

Downstream 100 bases:

>100_bases
GCGCCCGTGCCGCTGACCGGACCGATCGTGCTGTCGGACAATCGCTACGGCAAGTCCGAGAACCGCATCGTGCGCATCCA
CCGGGACGGGCCGCGGCACG

Product: hypothetical protein

Products: NA

Alternate protein names: HIU hydrolase; HIUHase; Transthyretin-like protein; TLP; Transthyretin-related protein; TRP [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSTPGTSTLSTHVLDAVRGVPAAGVAVTLYAGAEPVASGATDADGRIGGLAEVSPGTYRLVFDTGAYFAAQGTPTFYPEV
AITFAVTEERHHHVPLLLSPFAFSTYRGS

Sequences:

>Translated_109_residues
MSTPGTSTLSTHVLDAVRGVPAAGVAVTLYAGAEPVASGATDADGRIGGLAEVSPGTYRLVFDTGAYFAAQGTPTFYPEV
AITFAVTEERHHHVPLLLSPFAFSTYRGS
>Mature_108_residues
STPGTSTLSTHVLDAVRGVPAAGVAVTLYAGAEPVASGATDADGRIGGLAEVSPGTYRLVFDTGAYFAAQGTPTFYPEVA
ITFAVTEERHHHVPLLLSPFAFSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4507725, Length=107, Percent_Identity=37.3831775700935, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788281, Length=111, Percent_Identity=43.2432432432432, Blast_Score=94, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115532920, Length=112, Percent_Identity=40.1785714285714, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532922, Length=112, Percent_Identity=40.1785714285714, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534555, Length=112, Percent_Identity=40.1785714285714, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24652571, Length=108, Percent_Identity=39.8148148148148, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 11244; Mature: 11112

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPGTSTLSTHVLDAVRGVPAAGVAVTLYAGAEPVASGATDADGRIGGLAEVSPGTYRL
CCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEE
VFDTGAYFAAQGTPTFYPEVAITFAVTEERHHHVPLLLSPFAFSTYRGS
EEECCCEEEECCCCCCCCCEEEEEEEECCCCCCCCEEECCCCCEEECCC
>Mature Secondary Structure 
STPGTSTLSTHVLDAVRGVPAAGVAVTLYAGAEPVASGATDADGRIGGLAEVSPGTYRL
CCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEE
VFDTGAYFAAQGTPTFYPEVAITFAVTEERHHHVPLLLSPFAFSTYRGS
EEECCCEEEECCCCCCCCCEEEEEEEECCCCCCCCEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9723926 [H]