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The map label for this gene is qorA [H]

Identifier: 54027058

GI number: 54027058

Start: 5382687

End: 5383661

Strand: Reverse

Name: qorA [H]

Synonym: nfa50840

Alternate gene names: 54027058

Gene position: 5383661-5382687 (Counterclockwise)

Preceding gene: 54027063

Following gene: 54027057

Centisome position: 89.41

GC content: 72.1

Gene sequence:

>975_bases
ATGCGCGCAGCTCAGGTCAGCAGGTTGGAAGGACCGGAAGCGGTCGAGATCGTCGACATCCCCGAACCCGCCGCCTTCCC
CGGCGGTGTGGTCATCGATGTGCATGCCGCCGGCGTGGCGTTCCCCGACGTGCTGATGACCCGCGGGCTCTACCAGATGA
AGCCGGAGCTGCCGTTCGTGGTGGGCGGCGAGGTGGCGGGCGTGGTGCGCGAGGCCCCCGAGGGCGCGCATGTGCGCCCC
GGCGACCGGGTGCTGGCGCTGACCATGCTCGGCAACGCCATCGCCGAGGTCGCGGTGACCCCGGCGGAGATGGTGTTCAA
GCTGCCGGACAACATCTCGATGGAGGCCGGCGCGGGCATTCTGTTCAACGACCTGACCGTGCACTTCTGCCTGCGCAACC
GCGGCAGGCTCGCGCCGGGGGAGACGGTGCTGGTGCACGGCGCCGCGGGCGGCATCGGCACCTCGACGCTGCGGATGGCC
GCCGCGCTCGGGGCGAGCCGGGTGGTCGCGGTGGTGAGCACGCCGGAGAAGGCCGAGGTCGCCAAGGCCAACGGCGCCAC
CGACGTGGTGCTCACCGAGGGCTGGCTGGCGGCGGTGAAGGAACTGACCGGCGGGCGCGGGGTGGACATCGTGCTCGACC
CGGTGGGTGGGGACCGGTTCACCGACAGCATTCGCTCGCTGGCCTCGGCGGGCCGCCTGCTGGTCGTCGGCTTCACCGCC
GGTGAGATCCCGACGGTGAAGGTGAACCGCCTGCTGTTGAAGAACGTCGAGGTGGTCGGCGCGGCGTGGGGCGAGTGGGT
GATGTCGCACCCCGGTTACCTGGCCGAGCAGTGGGCCGAGGTGGAGCCGCTGTTGGCCTCGGGCGCGATCGCGCCGCCGC
AGCCGGTGCTGTACCCGCTGGAGCGGGCCGCCGAGGCGGTCGCCTCGCTGGACAATCGCACCGCCACCGGCAAGGTGGTC
GTGACGGTCCGCTGA

Upstream 100 bases:

>100_bases
TGGACTGTGCGCCGAGCAGTATCCACAGCCTGCCCGTTATGTTGGTCACGGTGTCATCGACGACGACCGATGTCGTCGAA
TCGGACAGAGAGGTCGGCCC

Downstream 100 bases:

>100_bases
CGTGCCGCTGTCGGCCAGGGTGCTCAACCGCACCCTGCTCGAGCGCCAGCATCTGCTGGCGCGGTCGGAGCTGTCGGTGC
CGCGGATGTGCGAGCACCTG

Product: putative dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRAAQVSRLEGPEAVEIVDIPEPAAFPGGVVIDVHAAGVAFPDVLMTRGLYQMKPELPFVVGGEVAGVVREAPEGAHVRP
GDRVLALTMLGNAIAEVAVTPAEMVFKLPDNISMEAGAGILFNDLTVHFCLRNRGRLAPGETVLVHGAAGGIGTSTLRMA
AALGASRVVAVVSTPEKAEVAKANGATDVVLTEGWLAAVKELTGGRGVDIVLDPVGGDRFTDSIRSLASAGRLLVVGFTA
GEIPTVKVNRLLLKNVEVVGAAWGEWVMSHPGYLAEQWAEVEPLLASGAIAPPQPVLYPLERAAEAVASLDNRTATGKVV
VTVR

Sequences:

>Translated_324_residues
MRAAQVSRLEGPEAVEIVDIPEPAAFPGGVVIDVHAAGVAFPDVLMTRGLYQMKPELPFVVGGEVAGVVREAPEGAHVRP
GDRVLALTMLGNAIAEVAVTPAEMVFKLPDNISMEAGAGILFNDLTVHFCLRNRGRLAPGETVLVHGAAGGIGTSTLRMA
AALGASRVVAVVSTPEKAEVAKANGATDVVLTEGWLAAVKELTGGRGVDIVLDPVGGDRFTDSIRSLASAGRLLVVGFTA
GEIPTVKVNRLLLKNVEVVGAAWGEWVMSHPGYLAEQWAEVEPLLASGAIAPPQPVLYPLERAAEAVASLDNRTATGKVV
VTVR
>Mature_324_residues
MRAAQVSRLEGPEAVEIVDIPEPAAFPGGVVIDVHAAGVAFPDVLMTRGLYQMKPELPFVVGGEVAGVVREAPEGAHVRP
GDRVLALTMLGNAIAEVAVTPAEMVFKLPDNISMEAGAGILFNDLTVHFCLRNRGRLAPGETVLVHGAAGGIGTSTLRMA
AALGASRVVAVVSTPEKAEVAKANGATDVVLTEGWLAAVKELTGGRGVDIVLDPVGGDRFTDSIRSLASAGRLLVVGFTA
GEIPTVKVNRLLLKNVEVVGAAWGEWVMSHPGYLAEQWAEVEPLLASGAIAPPQPVLYPLERAAEAVASLDNRTATGKVV
VTVR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=29.4303797468354, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI24308257, Length=325, Percent_Identity=28.3076923076923, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI41872631, Length=316, Percent_Identity=26.5822784810127, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI22538446, Length=334, Percent_Identity=25.748502994012, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI22538444, Length=334, Percent_Identity=25.748502994012, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI67078404, Length=322, Percent_Identity=26.3975155279503, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI67078406, Length=299, Percent_Identity=27.0903010033445, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI28557745, Length=346, Percent_Identity=28.0346820809249, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI47519420, Length=335, Percent_Identity=26.5671641791045, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=312, Percent_Identity=31.4102564102564, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17507255, Length=332, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=277, Percent_Identity=28.8808664259928, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556000, Length=315, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=324, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=332, Percent_Identity=28.0120481927711, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI221330659, Length=314, Percent_Identity=26.1146496815287, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19920632, Length=314, Percent_Identity=26.1146496815287, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45550423, Length=322, Percent_Identity=25.4658385093168, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24581345, Length=332, Percent_Identity=25.6024096385542, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33632; Mature: 33632

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAQVSRLEGPEAVEIVDIPEPAAFPGGVVIDVHAAGVAFPDVLMTRGLYQMKPELPFV
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCHHHCCCCCCEE
VGGEVAGVVREAPEGAHVRPGDRVLALTMLGNAIAEVAVTPAEMVFKLPDNISMEAGAGI
ECCHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCE
LFNDLTVHFCLRNRGRLAPGETVLVHGAAGGIGTSTLRMAAALGASRVVAVVSTPEKAEV
EEHHHEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCHHHH
AKANGATDVVLTEGWLAAVKELTGGRGVDIVLDPVGGDRFTDSIRSLASAGRLLVVGFTA
HHCCCCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECC
GEIPTVKVNRLLLKNVEVVGAAWGEWVMSHPGYLAEQWAEVEPLLASGAIAPPQPVLYPL
CCCCEEEHHHHHHHCHHEEECCHHHHHHCCCCHHHHHHHHHCHHHHCCCCCCCCCCCHHH
ERAAEAVASLDNRTATGKVVVTVR
HHHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure
MRAAQVSRLEGPEAVEIVDIPEPAAFPGGVVIDVHAAGVAFPDVLMTRGLYQMKPELPFV
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCHHHCCCCCCEE
VGGEVAGVVREAPEGAHVRPGDRVLALTMLGNAIAEVAVTPAEMVFKLPDNISMEAGAGI
ECCHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCE
LFNDLTVHFCLRNRGRLAPGETVLVHGAAGGIGTSTLRMAAALGASRVVAVVSTPEKAEV
EEHHHEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCHHHH
AKANGATDVVLTEGWLAAVKELTGGRGVDIVLDPVGGDRFTDSIRSLASAGRLLVVGFTA
HHCCCCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECC
GEIPTVKVNRLLLKNVEVVGAAWGEWVMSHPGYLAEQWAEVEPLLASGAIAPPQPVLYPL
CCCCEEEHHHHHHHCHHEEECCHHHHHHCCCCHHHHHHHHHCHHHHCCCCCCCCCCCHHH
ERAAEAVASLDNRTATGKVVVTVR
HHHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]