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The map label for this gene is cobM [H]

Identifier: 54027008

GI number: 54027008

Start: 5288618

End: 5289373

Strand: Reverse

Name: cobM [H]

Synonym: nfa50340

Alternate gene names: 54027008

Gene position: 5289373-5288618 (Counterclockwise)

Preceding gene: 54027010

Following gene: 54027007

Centisome position: 87.85

GC content: 70.9

Gene sequence:

>756_bases
ATGACCGTGCATTTCATCGGGGCCGGGCCGGGCGCGGCGGACCTGCTGACCGTGCGTGCGGTGAATCTGCTGCGCACGAG
TCCTGTCTGTCTCTACGCGGGGACCTATCTCGATCCGGCGGTGTTGGCGCACTGTGCGCCGGAGACCGAGTTGATCGACA
CCCAGCATCTGGATCTGGACCAGATCACCGCGCATCTGGTGCGGGCGCATGACGCGGGCAAGGATGTGGCTCGGTTGTGT
TCGGGTGATCCGTCGGTGTACTCGGCGCTGACCGAGCAGACCCGGCGGCTGGACGCGCACGGTGTGCCGTGGGATGTCAC
GCCCGGTGTGCCCGCCTATGCGGCGGCGGCGGCGTTGCTGGGGACCGAGCTGACCGTTCCCGAAGTGGTGCAGTCGGTGG
TGCTGACCCGTACGCAGCGCCGGTCGACGGCGATGCCCGAGTCCGAGGCGCTGGGGGAGTTCGCGCGCACCGGCGCCACC
CTCGTGCTGCATCTGGCGATCACGCGGACCAGGGAGCTGGCCGCCGAGCTGGCCGCGCATTACGGCGCCGACTGTCCGGT
CGCGGTGGTCCACCGGGCCAGTCAGCCCGAGGAACTGGTGCTGCGCGGCACTCTCGCCGACATCGCCGACCGGGTGGAGG
CGGCGGGGCTGCGGCAGGCGGCGGTGATCCTGGTCGGGCGGGCCCTCACCCCGGCCGTCGCCTGCACCACCTCACACCTG
TACGACCCGGCCCGTGAGCGACATCTCACCCCCTGA

Upstream 100 bases:

>100_bases
CCCACGTGCCTGGTCCGTCGACGACCCATGACCACCGCAGCCCGGACCGCTGACCACCGCAGCCCGGACCGCCCATCCGG
AGATCCCTACACTCACCCCC

Downstream 100 bases:

>100_bases
TCCGGGCCGGGCCGATGACCTGCGGTGTCCAAGATGTGAGATGGGTGACAGAGGTTTGCCGGAAGGGTGCCGCCCCGTTC
TGCCTGGTGTGATGCACTGG

Product: putative methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTVHFIGAGPGAADLLTVRAVNLLRTSPVCLYAGTYLDPAVLAHCAPETELIDTQHLDLDQITAHLVRAHDAGKDVARLC
SGDPSVYSALTEQTRRLDAHGVPWDVTPGVPAYAAAAALLGTELTVPEVVQSVVLTRTQRRSTAMPESEALGEFARTGAT
LVLHLAITRTRELAAELAAHYGADCPVAVVHRASQPEELVLRGTLADIADRVEAAGLRQAAVILVGRALTPAVACTTSHL
YDPARERHLTP

Sequences:

>Translated_251_residues
MTVHFIGAGPGAADLLTVRAVNLLRTSPVCLYAGTYLDPAVLAHCAPETELIDTQHLDLDQITAHLVRAHDAGKDVARLC
SGDPSVYSALTEQTRRLDAHGVPWDVTPGVPAYAAAAALLGTELTVPEVVQSVVLTRTQRRSTAMPESEALGEFARTGAT
LVLHLAITRTRELAAELAAHYGADCPVAVVHRASQPEELVLRGTLADIADRVEAAGLRQAAVILVGRALTPAVACTTSHL
YDPARERHLTP
>Mature_250_residues
TVHFIGAGPGAADLLTVRAVNLLRTSPVCLYAGTYLDPAVLAHCAPETELIDTQHLDLDQITAHLVRAHDAGKDVARLCS
GDPSVYSALTEQTRRLDAHGVPWDVTPGVPAYAAAAALLGTELTVPEVVQSVVLTRTQRRSTAMPESEALGEFARTGATL
VLHLAITRTRELAAELAAHYGADCPVAVVHRASQPEELVLRGTLADIADRVEAAGLRQAAVILVGRALTPAVACTTSHLY
DPARERHLTP

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=244, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322922, Length=251, Percent_Identity=26.2948207171315, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26577; Mature: 26445

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFIGAGPGAADLLTVRAVNLLRTSPVCLYAGTYLDPAVLAHCAPETELIDTQHLDLD
CEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHH
QITAHLVRAHDAGKDVARLCSGDPSVYSALTEQTRRLDAHGVPWDVTPGVPAYAAAAALL
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GTELTVPEVVQSVVLTRTQRRSTAMPESEALGEFARTGATLVLHLAITRTRELAAELAAH
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YGADCPVAVVHRASQPEELVLRGTLADIADRVEAAGLRQAAVILVGRALTPAVACTTSHL
HCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDPARERHLTP
CCCHHHCCCCC
>Mature Secondary Structure 
TVHFIGAGPGAADLLTVRAVNLLRTSPVCLYAGTYLDPAVLAHCAPETELIDTQHLDLD
EEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHH
QITAHLVRAHDAGKDVARLCSGDPSVYSALTEQTRRLDAHGVPWDVTPGVPAYAAAAALL
HHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GTELTVPEVVQSVVLTRTQRRSTAMPESEALGEFARTGATLVLHLAITRTRELAAELAAH
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YGADCPVAVVHRASQPEELVLRGTLADIADRVEAAGLRQAAVILVGRALTPAVACTTSHL
HCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDPARERHLTP
CCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]