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The map label for this gene is engD [H]

Identifier: 54026759

GI number: 54026759

Start: 4994742

End: 4995821

Strand: Reverse

Name: engD [H]

Synonym: nfa47850

Alternate gene names: 54026759

Gene position: 4995821-4994742 (Counterclockwise)

Preceding gene: 54026766

Following gene: 54026757

Centisome position: 82.97

GC content: 67.31

Gene sequence:

>1080_bases
GTGAGTCTCACCCTCGGAATCGTCGGCCTGCCCAACGTCGGAAAGTCGACGCTGTTCAACGCGCTGACCAAGAACGACGT
GCTGGCCGCGAACTACCCGTTCGCGACCATCGAACCCAACGTCGGCGTGGTCCCGCTGCCGGACCCGAGGCTGGAGAAGC
TGGCCGAGATCTTCGGCTCCGAGCGCATCGTGCCCGCCACCGTGTCGTTCGTCGACATCGCCGGCATCGTCAAGGGCGCC
TCCGAGGGCGCGGGCCTGGGCAACAAGTTCCTCGCCAACATCCGCGAAGCCGACGCGATCTGCCAGGTGGTGCGCGTGTT
CGCCGACGACGACGTGGTGCACGTCGACGGCCGCGTCGACCCCGCCGCCGACATCGAGGTCATCGAAACCGAGCTCATCC
TCGCCGACCTGCAGACCCTGGAGAAGGCCGTCGTCCGTCTCGACAAGGAAGCCAAGGTCAAGAAGGACCGCAAGCCCGTC
GCCGACGCCGCCAAGGCCGCCCGGGAGATCCTCAACAGCGGAAAGACCCTGTTCGCCGCCCGGAACGAGGTCGACACCGA
CCTGCTCAAGGAACTGTCGCTGCTGACCATCAAGCCGTTCCTGTACGTCTTCAACGCCGACGAGTCCGTGCTCACCGACG
AGGCACGCAAGGAGTCGCTGAAGGCCTCCGTGGCCCCCGCCGACGCGGTGTTCCTCGACGCCAAGGTGGAAGCCGAGCTC
CTCGAACTCGACGCCGAATCCGCCGCCGAACTGCTCGAATCCATCGGCCAGACCGAACCGGGCCTGCACGCCCTCGCCCG
CGCCGGCTTCCACACCCTCGGCCTGCAGACCTACCTGACCGCCGGGCCCAAGGAAGCGCGGGCGTGGACCATTCACCAGG
GCGACACCGCCCCGAAGGCCGCAGGCGTCATCCACACCGACTTCGAGCGCGGCTTCATCAAGGCCGAGATCGTGGCGTTC
GACGACCTGGTCGAGGCGGGGTCGATGGCGGCCGCCAAGGCCGCGGGCAAGGTGCGGATGGAAGGTAAGGACTACGTCAT
GGCCGACGGCGACGTCGTGGAGTTCCGCTTCAACGTGTAG

Upstream 100 bases:

>100_bases
GGTGGTCGGCTCCATGCGTTCACGCTACGCCCGCCCACCGACCGGCACGAGCGACGGCGCCGCTCGGCGCCCGCGGCCCG
GCGCGTAGACTTTCCGACCT

Downstream 100 bases:

>100_bases
TCCGATGGTGCGGTGAATCGGGCGATTGCCCACAGGAGCAGCCCCGACGCCGCATAGCCCGCGCCGAGCCAGCACGACGC
CGCCCAGCCCCACGCGCTGT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSLTLGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVPLPDPRLEKLAEIFGSERIVPATVSFVDIAGIVKGA
SEGAGLGNKFLANIREADAICQVVRVFADDDVVHVDGRVDPAADIEVIETELILADLQTLEKAVVRLDKEAKVKKDRKPV
ADAAKAAREILNSGKTLFAARNEVDTDLLKELSLLTIKPFLYVFNADESVLTDEARKESLKASVAPADAVFLDAKVEAEL
LELDAESAAELLESIGQTEPGLHALARAGFHTLGLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHTDFERGFIKAEIVAF
DDLVEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRFNV

Sequences:

>Translated_359_residues
MSLTLGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVPLPDPRLEKLAEIFGSERIVPATVSFVDIAGIVKGA
SEGAGLGNKFLANIREADAICQVVRVFADDDVVHVDGRVDPAADIEVIETELILADLQTLEKAVVRLDKEAKVKKDRKPV
ADAAKAAREILNSGKTLFAARNEVDTDLLKELSLLTIKPFLYVFNADESVLTDEARKESLKASVAPADAVFLDAKVEAEL
LELDAESAAELLESIGQTEPGLHALARAGFHTLGLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHTDFERGFIKAEIVAF
DDLVEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRFNV
>Mature_358_residues
SLTLGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVPLPDPRLEKLAEIFGSERIVPATVSFVDIAGIVKGAS
EGAGLGNKFLANIREADAICQVVRVFADDDVVHVDGRVDPAADIEVIETELILADLQTLEKAVVRLDKEAKVKKDRKPVA
DAAKAAREILNSGKTLFAARNEVDTDLLKELSLLTIKPFLYVFNADESVLTDEARKESLKASVAPADAVFLDAKVEAELL
ELDAESAAELLESIGQTEPGLHALARAGFHTLGLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHTDFERGFIKAEIVAFD
DLVEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=372, Percent_Identity=42.2043010752688, Blast_Score=281, Evalue=9e-76,
Organism=Homo sapiens, GI58761502, Length=238, Percent_Identity=37.3949579831933, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=51.2396694214876, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=32.3076923076923, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=378, Percent_Identity=40.7407407407407, Blast_Score=261, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=39.7849462365591, Blast_Score=241, Evalue=9e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=384, Percent_Identity=35.4166666666667, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=160, Percent_Identity=36.875, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=41.9618528610354, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=41.9618528610354, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=41.9618528610354, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=40, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24585318, Length=151, Percent_Identity=31.1258278145695, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38361; Mature: 38230

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTLGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVPLPDPRLEKLAEIFGS
CCEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCCHHHHHHHHHHCC
ERIVPATVSFVDIAGIVKGASEGAGLGNKFLANIREADAICQVVRVFADDDVVHVDGRVD
CCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PAADIEVIETELILADLQTLEKAVVRLDKEAKVKKDRKPVADAAKAAREILNSGKTLFAA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEE
RNEVDTDLLKELSLLTIKPFLYVFNADESVLTDEARKESLKASVAPADAVFLDAKVEAEL
CCCCCHHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHH
LELDAESAAELLESIGQTEPGLHALARAGFHTLGLQTYLTAGPKEARAWTIHQGDTAPKA
HHCCHHHHHHHHHHHCCCCCCHHHHHHCCHHHHCHHHHCCCCCCCCCEEEEECCCCCCCC
AGVIHTDFERGFIKAEIVAFDDLVEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRFNV
CCEEEECCCCCCEEEEEEEHHHHHHHCCHHHHHHCCEEEECCCCEEEECCCEEEEEECC
>Mature Secondary Structure 
SLTLGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVPLPDPRLEKLAEIFGS
CEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCCHHHHHHHHHHCC
ERIVPATVSFVDIAGIVKGASEGAGLGNKFLANIREADAICQVVRVFADDDVVHVDGRVD
CCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PAADIEVIETELILADLQTLEKAVVRLDKEAKVKKDRKPVADAAKAAREILNSGKTLFAA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEE
RNEVDTDLLKELSLLTIKPFLYVFNADESVLTDEARKESLKASVAPADAVFLDAKVEAEL
CCCCCHHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHH
LELDAESAAELLESIGQTEPGLHALARAGFHTLGLQTYLTAGPKEARAWTIHQGDTAPKA
HHCCHHHHHHHHHHHCCCCCCHHHHHHCCHHHHCHHHHCCCCCCCCCEEEEECCCCCCCC
AGVIHTDFERGFIKAEIVAFDDLVEAGSMAAAKAAGKVRMEGKDYVMADGDVVEFRFNV
CCEEEECCCCCCEEEEEEEHHHHHHHCCHHHHHHCCEEEECCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA