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The map label for this gene is pfpI [H]

Identifier: 54026332

GI number: 54026332

Start: 4523326

End: 4523883

Strand: Reverse

Name: pfpI [H]

Synonym: nfa43610

Alternate gene names: 54026332

Gene position: 4523883-4523326 (Counterclockwise)

Preceding gene: 54026333

Following gene: 54026331

Centisome position: 75.13

GC content: 71.33

Gene sequence:

>558_bases
ATGGCCGAACTGGACGGTGTCCGGGTGCTGATCGTGACGTCGAACACCGGGGTCGAACGCGACGAACTGCTGGTGCCGCG
CGACCGGCTGCGCGAACGCGGCGCCCGGGTGACCCACGCGGCGCCGAAACCGGAGCAGGTGCAGACCTTCCAGCACGATC
TCGACCCGGCGCAGGCCGTGGAACCCGACAGCGCGCTCGACGGCGTCGACGCCGACGACTTCGACGTGCTGGTGGTCCCC
GGCGGCACGGTCAACGCCGACAAGCTGCGCCTGGAGGACCGCGCGGTGGCGTTGGCCAAGGACTTCGCGGGCGCGGGCAA
ACCGATCGCCGCGATCTGCCACGGCCCGTGGCTGCTCGCCGAAGCCGACCTGGTGTCGGACAAGACGCTCACCTCGTATC
CGTCGCTGCGCACCGACCTGGGCAACGCGGGCGGCCGGTGGGTGGACGAACCGGTGGTCCGCTCGACCGAGCGGGACTGG
ACCCTGATCACCTCCCGCAACCCCGGTGACCTGGACGACTTCGTGACCGCGATCGTGCGCGAGGTCTCGGCCCGCTGA

Upstream 100 bases:

>100_bases
CGGGGTGGGCGCACCGGTGCCGAGGCCGGGCGACGTTTAGCCGTCCGCCCGTGCGGCATGCCTTCCGGTGAGAAGTTCCG
CCGATGGGAAGGAGTGACCG

Downstream 100 bases:

>100_bases
CCGGGCCTGCGGTTTCGCCGGACGCGCGCCGGGTACCTGCCGGTCGTCGGCACCGGTCGGCGGCAGGCACACCCGGAAAG
GAGCGGCATGAGTGGTCGGC

Product: putative protease

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAELDGVRVLIVTSNTGVERDELLVPRDRLRERGARVTHAAPKPEQVQTFQHDLDPAQAVEPDSALDGVDADDFDVLVVP
GGTVNADKLRLEDRAVALAKDFAGAGKPIAAICHGPWLLAEADLVSDKTLTSYPSLRTDLGNAGGRWVDEPVVRSTERDW
TLITSRNPGDLDDFVTAIVREVSAR

Sequences:

>Translated_185_residues
MAELDGVRVLIVTSNTGVERDELLVPRDRLRERGARVTHAAPKPEQVQTFQHDLDPAQAVEPDSALDGVDADDFDVLVVP
GGTVNADKLRLEDRAVALAKDFAGAGKPIAAICHGPWLLAEADLVSDKTLTSYPSLRTDLGNAGGRWVDEPVVRSTERDW
TLITSRNPGDLDDFVTAIVREVSAR
>Mature_184_residues
AELDGVRVLIVTSNTGVERDELLVPRDRLRERGARVTHAAPKPEQVQTFQHDLDPAQAVEPDSALDGVDADDFDVLVVPG
GTVNADKLRLEDRAVALAKDFAGAGKPIAAICHGPWLLAEADLVSDKTLTSYPSLRTDLGNAGGRWVDEPVVRSTERDWT
LITSRNPGDLDDFVTAIVREVSAR

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=184, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI31543380, Length=184, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082219, Length=166, Percent_Identity=34.9397590361446, Blast_Score=88, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571932, Length=169, Percent_Identity=33.1360946745562, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20046; Mature: 19914

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELDGVRVLIVTSNTGVERDELLVPRDRLRERGARVTHAAPKPEQVQTFQHDLDPAQAV
CCCCCCEEEEEEECCCCCCHHHEECCHHHHHHCCCEECCCCCCCHHHHHHHHCCCHHHHC
EPDSALDGVDADDFDVLVVPGGTVNADKLRLEDRAVALAKDFAGAGKPIAAICHGPWLLA
CCCCCCCCCCCCCCEEEEECCCCCCHHHEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEE
EADLVSDKTLTSYPSLRTDLGNAGGRWVDEPVVRSTERDWTLITSRNPGDLDDFVTAIVR
ECCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
EVSAR
HHHCC
>Mature Secondary Structure 
AELDGVRVLIVTSNTGVERDELLVPRDRLRERGARVTHAAPKPEQVQTFQHDLDPAQAV
CCCCCEEEEEEECCCCCCHHHEECCHHHHHHCCCEECCCCCCCHHHHHHHHCCCHHHHC
EPDSALDGVDADDFDVLVVPGGTVNADKLRLEDRAVALAKDFAGAGKPIAAICHGPWLLA
CCCCCCCCCCCCCCEEEEECCCCCCHHHEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEE
EADLVSDKTLTSYPSLRTDLGNAGGRWVDEPVVRSTERDWTLITSRNPGDLDDFVTAIVR
ECCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
EVSAR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]