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The map label for this gene is ycgM [C]

Identifier: 54026188

GI number: 54026188

Start: 4367281

End: 4368054

Strand: Reverse

Name: ycgM [C]

Synonym: nfa42170

Alternate gene names: 54026188

Gene position: 4368054-4367281 (Counterclockwise)

Preceding gene: 54026190

Following gene: 54026187

Centisome position: 72.54

GC content: 68.73

Gene sequence:

>774_bases
ATGCGTCTAGGTCGAGTTGCCAGTCCCGAAGGGGTCGCGTTCGTCAGCATCGAGGGGGAGGGTGCCGACGCCGTCACCAA
GGAGATCGCCGAGCATCCGTTCGGTACGCCGACGTTCACCGGGCGCAGCTGGCCGCTGGCCGACGTGCGCCTGCTCGCGC
CGATCCTGGCCAGCAAGGTCGTCTGCGTGGGCAAGAACTACGCGGCGCACGCGGCCGAGATGGGCGGCGAGGCGCCCGAG
CAGCCGGTGATCTTCATCAAACCCAACACCGCCATCGTCGGCCCGCACGCGCCGATCATCGTGCCGCCCAGCTCCCAGCA
GGTGGACTACGAGGGCGAACTGGCGGTCGTGATCGGCCGTCCCTGCAAGGACGTGTCCGCCGCCCGCGCGCGCGAGGTCA
TCCTGGGCTACACCGTCGCCAACGACGTGACCGCCCGCGATCAGCAGCGCCAGGACGGCCAGTGGACCAGGGCCAAGGGC
TACGACACCTTCTGCCCGCTCGGTCCGTGGATCGAAACCGCCCTGGACCCCGCGGATCTGGAGATCCGCACCGAGCTCGA
CGGCGAGGTGCGCCAGCGCAGCCGCACCTCGCTGCTGCTGCACGACATTCCGAAGCTCATCGAATGGGTGAGCACGGTCA
TGACGCTGCTGCCCGGCGACGTGATCCTCACCGGAACACCCGAGGGCGTCGGTCCGATGCAGGTCGGACAGCAGGTGTCG
GTCACCGTCGAGGGAATCGGCACCCTGACCAATCCCGTTGCCGCCAAACGCTGA

Upstream 100 bases:

>100_bases
CCGGGCGGCGAGGTGCCGCGGGCGAGGAATCTCACATCGCGCGCGCCCGCGCGTACGGGCGCGCATCGCGGCGACCAGCG
GCTTCCGTAGACTCCCCACC

Downstream 100 bases:

>100_bases
TCGAGAGAGAGTCATGACAGAAGTACGGGTCCGTTTCTGCCCGTCGCCGACCGGGACGCCGCACGTCGGCCTGATCCGCA
CGGCCCTGTTCAACTGGGCC

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRLGRVASPEGVAFVSIEGEGADAVTKEIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYAAHAAEMGGEAPE
QPVIFIKPNTAIVGPHAPIIVPPSSQQVDYEGELAVVIGRPCKDVSAARAREVILGYTVANDVTARDQQRQDGQWTRAKG
YDTFCPLGPWIETALDPADLEIRTELDGEVRQRSRTSLLLHDIPKLIEWVSTVMTLLPGDVILTGTPEGVGPMQVGQQVS
VTVEGIGTLTNPVAAKR

Sequences:

>Translated_257_residues
MRLGRVASPEGVAFVSIEGEGADAVTKEIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYAAHAAEMGGEAPE
QPVIFIKPNTAIVGPHAPIIVPPSSQQVDYEGELAVVIGRPCKDVSAARAREVILGYTVANDVTARDQQRQDGQWTRAKG
YDTFCPLGPWIETALDPADLEIRTELDGEVRQRSRTSLLLHDIPKLIEWVSTVMTLLPGDVILTGTPEGVGPMQVGQQVS
VTVEGIGTLTNPVAAKR
>Mature_257_residues
MRLGRVASPEGVAFVSIEGEGADAVTKEIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYAAHAAEMGGEAPE
QPVIFIKPNTAIVGPHAPIIVPPSSQQVDYEGELAVVIGRPCKDVSAARAREVILGYTVANDVTARDQQRQDGQWTRAKG
YDTFCPLGPWIETALDPADLEIRTELDGEVRQRSRTSLLLHDIPKLIEWVSTVMTLLPGDVILTGTPEGVGPMQVGQQVS
VTVEGIGTLTNPVAAKR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=222, Percent_Identity=43.6936936936937, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI156231349, Length=222, Percent_Identity=44.1441441441441, Blast_Score=177, Evalue=6e-45,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=37.8109452736318, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI66348062, Length=194, Percent_Identity=38.1443298969072, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI215422413, Length=194, Percent_Identity=38.1443298969072, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=44.6153846153846, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17557057, Length=190, Percent_Identity=39.4736842105263, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6324161, Length=222, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28572127, Length=221, Percent_Identity=37.5565610859729, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=35.7843137254902, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24663695, Length=217, Percent_Identity=34.5622119815668, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27461; Mature: 27461

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGRVASPEGVAFVSIEGEGADAVTKEIAEHPFGTPTFTGRSWPLADVRLLAPILASKV
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCE
VCVGKNYAAHAAEMGGEAPEQPVIFIKPNTAIVGPHAPIIVPPSSQQVDYEGELAVVIGR
EEECCCCHHHHHHHCCCCCCCCEEEECCCEEEECCCCCEEECCCCCCCCCCCCEEEEECC
PCKDVSAARAREVILGYTVANDVTARDQQRQDGQWTRAKGYDTFCPLGPWIETALDPADL
CCCHHHHHHHHHEEEEEEECCCCCCCCHHHCCCCEEECCCCCCCCCCCHHHHHCCCCCCE
EIRTELDGEVRQRSRTSLLLHDIPKLIEWVSTVMTLLPGDVILTGTPEGVGPMQVGQQVS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHCCCEEE
VTVEGIGTLTNPVAAKR
EEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRLGRVASPEGVAFVSIEGEGADAVTKEIAEHPFGTPTFTGRSWPLADVRLLAPILASKV
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCE
VCVGKNYAAHAAEMGGEAPEQPVIFIKPNTAIVGPHAPIIVPPSSQQVDYEGELAVVIGR
EEECCCCHHHHHHHCCCCCCCCEEEECCCEEEECCCCCEEECCCCCCCCCCCCEEEEECC
PCKDVSAARAREVILGYTVANDVTARDQQRQDGQWTRAKGYDTFCPLGPWIETALDPADL
CCCHHHHHHHHHEEEEEEECCCCCCCCHHHCCCCEEECCCCCCCCCCCHHHHHCCCCCCE
EIRTELDGEVRQRSRTSLLLHDIPKLIEWVSTVMTLLPGDVILTGTPEGVGPMQVGQQVS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHCCCEEE
VTVEGIGTLTNPVAAKR
EEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]