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The map label for this gene is coaD

Identifier: 54026160

GI number: 54026160

Start: 4336156

End: 4336641

Strand: Reverse

Name: coaD

Synonym: nfa41890

Alternate gene names: 54026160

Gene position: 4336641-4336156 (Counterclockwise)

Preceding gene: 54026161

Following gene: 54026158

Centisome position: 72.02

GC content: 65.23

Gene sequence:

>486_bases
ATGGCTGGAGCACTGTGCCCCGGGTCCTTCGATCCGGTGACGAACGGACATCTCGACGTATTCACCCGCGCGGCGGCGCA
ATTCGACGAAGTCGTGGTGACCGTCATGATCAACCCGAACAAGAAGGGCATGTTCGACGTCGAGGAGCGCATGGAGCTGC
TGCGCGAGACCACCGCGCATCTGCCCAACGTGCGGGTCGCGTCCTGGCGGGGCCTGCTGGTGGACTTCGCCCGTGAGCAG
GGCATCACCGCGATCGTCAAGGGGCTGCGCGATGCCACCGACTTCGGCTACGAGCTGCAGATGGCGCAGATGAACAAGAA
GCTGTCCGGCGTGGACACCTTCTTCATCGCCACCAATCCGGCGTTCAGCTTCCTGTCCAGCTCACTGGTCAAGGAGGTCG
CCACCTACGGCGGCGACGTCAGCGACATGCTGCCGCCGGTGGTGCACAAGCGGCTGCTGGACCGGATCGCCGAGCGGCGC
GGCTGA

Upstream 100 bases:

>100_bases
CGCGACGGTACGGCGAGACGCGGCTGGAACTGGCCGAGTACGCGCCCGGAGCGGACTGAGCGGCGCGGCGGGGCGGGCGC
GGGCCTGATAGCGTCGGCCC

Downstream 100 bases:

>100_bases
GGCTCGGGCCGCGGCGGGTCCGGGCCGCGGCTCGTCGTCCAGCAGACGCGCTGTCTAGAAGACCAGGCCGCGCAGCGCGA
GGAAGCGCATGCCGCCCACC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAGALCPGSFDPVTNGHLDVFTRAAAQFDEVVVTVMINPNKKGMFDVEERMELLRETTAHLPNVRVASWRGLLVDFAREQ
GITAIVKGLRDATDFGYELQMAQMNKKLSGVDTFFIATNPAFSFLSSSLVKEVATYGGDVSDMLPPVVHKRLLDRIAERR
G

Sequences:

>Translated_161_residues
MAGALCPGSFDPVTNGHLDVFTRAAAQFDEVVVTVMINPNKKGMFDVEERMELLRETTAHLPNVRVASWRGLLVDFAREQ
GITAIVKGLRDATDFGYELQMAQMNKKLSGVDTFFIATNPAFSFLSSSLVKEVATYGGDVSDMLPPVVHKRLLDRIAERR
G
>Mature_160_residues
AGALCPGSFDPVTNGHLDVFTRAAAQFDEVVVTVMINPNKKGMFDVEERMELLRETTAHLPNVRVASWRGLLVDFAREQG
ITAIVKGLRDATDFGYELQMAQMNKKLSGVDTFFIATNPAFSFLSSSLVKEVATYGGDVSDMLPPVVHKRLLDRIAERRG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=46.4516129032258, Blast_Score=156, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_NOCFA (Q5YS03)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120402.1
- ProteinModelPortal:   Q5YS03
- SMR:   Q5YS03
- GeneID:   3108762
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa41890
- NMPDR:   fig|247156.1.peg.4039
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   NFAR247156:NFA41890-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17763; Mature: 17631

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGALCPGSFDPVTNGHLDVFTRAAAQFDEVVVTVMINPNKKGMFDVEERMELLRETTAH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
LPNVRVASWRGLLVDFAREQGITAIVKGLRDATDFGYELQMAQMNKKLSGVDTFFIATNP
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCH
AFSFLSSSLVKEVATYGGDVSDMLPPVVHKRLLDRIAERRG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGALCPGSFDPVTNGHLDVFTRAAAQFDEVVVTVMINPNKKGMFDVEERMELLRETTAH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
LPNVRVASWRGLLVDFAREQGITAIVKGLRDATDFGYELQMAQMNKKLSGVDTFFIATNP
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCH
AFSFLSSSLVKEVATYGGDVSDMLPPVVHKRLLDRIAERRG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA