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The map label for this gene is hur [H]

Identifier: 54025832

GI number: 54025832

Start: 4076273

End: 4077235

Strand: Reverse

Name: hur [H]

Synonym: nfa38620

Alternate gene names: 54025832

Gene position: 4077235-4076273 (Counterclockwise)

Preceding gene: 54025834

Following gene: 54025831

Centisome position: 67.71

GC content: 74.77

Gene sequence:

>963_bases
ATGCGCAGCCATCTCCCCACCGACGTCGCCGCCACCATCGATCGTGTCTTCGGCGCGCGCGGGGCGGCCTGGCTCGCCGG
GCTCGACGACGTCGTGGCCGAGCGCTGTGCCGAATGGGAGCTGACCGTGACCGGGCCCGGGTTCGGTGGGGGGACGCACT
CCTATGTGGCGCCGGTGCGGCGGGCGGACGGGTCCGACGCGGTGCTGAAGGTGCCCGTGGTGGACGAGGAGAACGTCGGT
GAGCCGACCGGGTTGGCCTGCTACGACGGCGACGGCGCGGTCCGGTTGTACGCCTTCGATCCCGGCACCGGTGCCATGCT
GCTCGAACGGGCGCGACCCGGCACCGAACTGCTGACCCAGCCGGGCTTCCCGAGCCTGGAGGGCAGGCCGGAGCACCGGG
ATCGGATCGAGCTGGCGTGCCGGCTGTACCGTCGCCTGCGCCGTCCGCCCGCCGAACTGCCCGCCGGATTCCCGCCGCTG
CCCGCCGCACTCGACATGGTCGCCGGGTGGACCGCGGCGTTGCGCAGGCCGGCGGCCGGTTTCGCCGAGGTGCTCGGACC
GCGGCTGCGCGCCGACGCGCTGGACTGGTGCGCGCGCCTGGCCGAACCGGACGGGCCGCTGCTGGTGGTCAACCGCGACA
CCCACCTGGGCAACATCGTGGCGGCCGAGCGGGAGCCGTGGCTGCTCATCGACCCGAAGTCCTACCTCGGCGAGGCCGCC
TTCGACGCAGGCTTCCTGATCATGATCCAGGTGCAGAGCGCGCCCGAGCCCGCGCACGCCGCCGCGGTCGTCGCGCGCAC
GGCGGACTGGCTCGGCATCGATCCCGAGCGGGCCCGGGGCTGGGCCTTCCTGCGGGCGGTCGAGGAGATCGGGTGGGCGA
TCGAGGACGACGAGCCCGGCCTGCTGCGGCTGCACCGCGCGGTGGCGCAGGCGCTGTCCGGGGGCGGCCGCGCCGCTGTG
TAA

Upstream 100 bases:

>100_bases
TCACACCGACCAGCAGCAGGTCCAGCGAATCGAGAAAGGCGAACCCCGCCAGCGCGGGCAACAGCGTCAACATGGCCTGT
CCGAACATACGCTGTGTCCC

Downstream 100 bases:

>100_bases
TCATGGCAACACACCCGCAAAGCCGACAGAACCAGACAAATCCGGCATGATGGCTGACATGACCGTCGAACGGAGTTCCG
CATGCAGGTGAGCGCGCTCG

Product: putative streptomycin 6-O-phosphotransferase

Products: NA

Alternate protein names: Hydroxyurea resistance protein [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MRSHLPTDVAATIDRVFGARGAAWLAGLDDVVAERCAEWELTVTGPGFGGGTHSYVAPVRRADGSDAVLKVPVVDEENVG
EPTGLACYDGDGAVRLYAFDPGTGAMLLERARPGTELLTQPGFPSLEGRPEHRDRIELACRLYRRLRRPPAELPAGFPPL
PAALDMVAGWTAALRRPAAGFAEVLGPRLRADALDWCARLAEPDGPLLVVNRDTHLGNIVAAEREPWLLIDPKSYLGEAA
FDAGFLIMIQVQSAPEPAHAAAVVARTADWLGIDPERARGWAFLRAVEEIGWAIEDDEPGLLRLHRAVAQALSGGGRAAV

Sequences:

>Translated_320_residues
MRSHLPTDVAATIDRVFGARGAAWLAGLDDVVAERCAEWELTVTGPGFGGGTHSYVAPVRRADGSDAVLKVPVVDEENVG
EPTGLACYDGDGAVRLYAFDPGTGAMLLERARPGTELLTQPGFPSLEGRPEHRDRIELACRLYRRLRRPPAELPAGFPPL
PAALDMVAGWTAALRRPAAGFAEVLGPRLRADALDWCARLAEPDGPLLVVNRDTHLGNIVAAEREPWLLIDPKSYLGEAA
FDAGFLIMIQVQSAPEPAHAAAVVARTADWLGIDPERARGWAFLRAVEEIGWAIEDDEPGLLRLHRAVAQALSGGGRAAV
>Mature_320_residues
MRSHLPTDVAATIDRVFGARGAAWLAGLDDVVAERCAEWELTVTGPGFGGGTHSYVAPVRRADGSDAVLKVPVVDEENVG
EPTGLACYDGDGAVRLYAFDPGTGAMLLERARPGTELLTQPGFPSLEGRPEHRDRIELACRLYRRLRRPPAELPAGFPPL
PAALDMVAGWTAALRRPAAGFAEVLGPRLRADALDWCARLAEPDGPLLVVNRDTHLGNIVAAEREPWLLIDPKSYLGEAA
FDAGFLIMIQVQSAPEPAHAAAVVARTADWLGIDPERARGWAFLRAVEEIGWAIEDDEPGLLRLHRAVAQALSGGGRAAV

Specific function: Potential phosphotransferase that inactivates hydroxyurea by phosphorylation of the hydroxy group in the hydroxylamine moiety [H]

COG id: COG3570

COG function: function code V; Streptomycin 6-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aminoglycoside phosphotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR006748 [H]

Pfam domain/function: PF04655 APH_6_hur [H]

EC number: NA

Molecular weight: Translated: 34261; Mature: 34261

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHLPTDVAATIDRVFGARGAAWLAGLDDVVAERCAEWELTVTGPGFGGGTHSYVAPVR
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
RADGSDAVLKVPVVDEENVGEPTGLACYDGDGAVRLYAFDPGTGAMLLERARPGTELLTQ
CCCCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEEECCCCCHHHHCCCCCCHHHHCC
PGFPSLEGRPEHRDRIELACRLYRRLRRPPAELPAGFPPLPAALDMVAGWTAALRRPAAG
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCH
FAEVLGPRLRADALDWCARLAEPDGPLLVVNRDTHLGNIVAAEREPWLLIDPKSYLGEAA
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCEEEECCHHHHCHHH
FDAGFLIMIQVQSAPEPAHAAAVVARTADWLGIDPERARGWAFLRAVEEIGWAIEDDEPG
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEECCCCCH
LLRLHRAVAQALSGGGRAAV
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRSHLPTDVAATIDRVFGARGAAWLAGLDDVVAERCAEWELTVTGPGFGGGTHSYVAPVR
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
RADGSDAVLKVPVVDEENVGEPTGLACYDGDGAVRLYAFDPGTGAMLLERARPGTELLTQ
CCCCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEEECCCCCHHHHCCCCCCHHHHCC
PGFPSLEGRPEHRDRIELACRLYRRLRRPPAELPAGFPPLPAALDMVAGWTAALRRPAAG
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCH
FAEVLGPRLRADALDWCARLAEPDGPLLVVNRDTHLGNIVAAEREPWLLIDPKSYLGEAA
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCEEEECCHHHHCHHH
FDAGFLIMIQVQSAPEPAHAAAVVARTADWLGIDPERARGWAFLRAVEEIGWAIEDDEPG
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEECCCCCH
LLRLHRAVAQALSGGGRAAV
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1316866 [H]