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The map label for this gene is yhaU [H]

Identifier: 54025731

GI number: 54025731

Start: 3979035

End: 3980210

Strand: Reverse

Name: yhaU [H]

Synonym: nfa37610

Alternate gene names: 54025731

Gene position: 3980210-3979035 (Counterclockwise)

Preceding gene: 54025732

Following gene: 54025727

Centisome position: 66.1

GC content: 70.49

Gene sequence:

>1176_bases
GTGAGCGGTACCGCGCTCGGGCTGCTCGAGCTCGGCGCTGTCCTGTTCGCTCTGGGGCTGCTCGGGCGGGTGGCGATGCG
GATCGGCATGTCGCCGATCCCGTTGTATCTGCTCGGCGGGCTCGCCTTCGGTTCCGGCGGTTTCACCGAACTGCATTCGG
CGGGCGAGTTCAGTCACCTCGCCGGTGAGATCGGTGTGGTGCTGCTGCTGTTGCTGCTCGGTCTCGAATACACCGCGGCC
GAGTTGGTGACCGGGCTGCGCCGATCGTGGGCGGCGGGTCTGTTCGACCTGGTCGCCAACGCCACCCCGGGTGCGCTGGT
GGCCCTGCTGCTCGGCTGGGGATTCACCGGCGCGATCACCATGGCCGGGGTCACCTACATCTCCTCCTCCGGGATCGTCG
CCAAGGTGCTCAACGATCTCGGCAGGCTCGGTAACCGCGAGACACCGGTGATCCTGTCGATCCTGGTGTTCGAGGATCTG
GCGATGGCGGTGTACCTGCCGATCCTCACCACCATCCTGGCCGGGCTGAGCTTCTTCAGCGGCATGAAGGCGCTGGGCAT
CGCGCTGGTGACGGTGACGCTGGTGCTGGTGGTCGCGCTGCGCTACGGCCGCTACGTGTCGGCCCTGGTCAACAGCCCCG
ACAACGAGGTGTTCCTGCTGAAGCTGCTCGGCGCCGCGCTGCTGGTGGCCGGGGCCGCCTCGGCGCTCAACGTCTCCGCG
GCGGTGGGCGCGTTCCTGCTCGGCATCGCGATCTCCGGCTCCACCGCCCATCAGGCGGTGAAGCTGCTCGAACCGCTGCG
CGATCTGTTCGCGGCGATCTTCTTCGTCGCCTTCGGCCTCAACACCGACCCGCGTGCGATCCCGCCGGTGCTGGGGTGGG
CGGTGGCGTTGGCGGTGCTGACCACGCTGACCAAGATCGGCACCGGGTGGTGGGCGGCGCGGCGGCAGGGCATCCGCCGG
ATGGGCCGGGCCAGGGCGGGTGCGGCACTGGTGGCGCGCGGCGAATTCTCCATCGTCATCGCCGGACTCGCGGTCACGAT
GGGCGCGGTCGACGGCAGGCTCGCGGCGCTGGCCTCGGCGTACGTGCTGTTGATGGCGGTGCTGGGGCCGGTCGCGGCCC
GGGTGGTGGAGCCGGTGGCCGGGTTCGCGCAACGGCGGCGCGCCCCCGCGCTGTGA

Upstream 100 bases:

>100_bases
GGTCCCGACTTCACCTTCGCCGCCGACGACATCCTGGTCGTCGTCGGCACACCCGACGGCTTGGACGCCGCCGCGAAGAT
TCTCACCCACGGATGACCCG

Downstream 100 bases:

>100_bases
GCGTCAGCGGCGGGCGCGGCGGATGTCGTCGGTCGTCGGCCAGTACGGCGTGCTCGACGGCGGCGCGACCGCCGCGACCG
GTGGGGCGGGTACCGGCTCG

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSGTALGLLELGAVLFALGLLGRVAMRIGMSPIPLYLLGGLAFGSGGFTELHSAGEFSHLAGEIGVVLLLLLLGLEYTAA
ELVTGLRRSWAAGLFDLVANATPGALVALLLGWGFTGAITMAGVTYISSSGIVAKVLNDLGRLGNRETPVILSILVFEDL
AMAVYLPILTTILAGLSFFSGMKALGIALVTVTLVLVVALRYGRYVSALVNSPDNEVFLLKLLGAALLVAGAASALNVSA
AVGAFLLGIAISGSTAHQAVKLLEPLRDLFAAIFFVAFGLNTDPRAIPPVLGWAVALAVLTTLTKIGTGWWAARRQGIRR
MGRARAGAALVARGEFSIVIAGLAVTMGAVDGRLAALASAYVLLMAVLGPVAARVVEPVAGFAQRRRAPAL

Sequences:

>Translated_391_residues
MSGTALGLLELGAVLFALGLLGRVAMRIGMSPIPLYLLGGLAFGSGGFTELHSAGEFSHLAGEIGVVLLLLLLGLEYTAA
ELVTGLRRSWAAGLFDLVANATPGALVALLLGWGFTGAITMAGVTYISSSGIVAKVLNDLGRLGNRETPVILSILVFEDL
AMAVYLPILTTILAGLSFFSGMKALGIALVTVTLVLVVALRYGRYVSALVNSPDNEVFLLKLLGAALLVAGAASALNVSA
AVGAFLLGIAISGSTAHQAVKLLEPLRDLFAAIFFVAFGLNTDPRAIPPVLGWAVALAVLTTLTKIGTGWWAARRQGIRR
MGRARAGAALVARGEFSIVIAGLAVTMGAVDGRLAALASAYVLLMAVLGPVAARVVEPVAGFAQRRRAPAL
>Mature_390_residues
SGTALGLLELGAVLFALGLLGRVAMRIGMSPIPLYLLGGLAFGSGGFTELHSAGEFSHLAGEIGVVLLLLLLGLEYTAAE
LVTGLRRSWAAGLFDLVANATPGALVALLLGWGFTGAITMAGVTYISSSGIVAKVLNDLGRLGNRETPVILSILVFEDLA
MAVYLPILTTILAGLSFFSGMKALGIALVTVTLVLVVALRYGRYVSALVNSPDNEVFLLKLLGAALLVAGAASALNVSAA
VGAFLLGIAISGSTAHQAVKLLEPLRDLFAAIFFVAFGLNTDPRAIPPVLGWAVALAVLTTLTKIGTGWWAARRQGIRRM
GRARAGAALVARGEFSIVIAGLAVTMGAVDGRLAALASAYVLLMAVLGPVAARVVEPVAGFAQRRRAPAL

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=376, Percent_Identity=28.4574468085106, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786232, Length=270, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789749, Length=369, Percent_Identity=27.10027100271, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 40179; Mature: 40048

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTALGLLELGAVLFALGLLGRVAMRIGMSPIPLYLLGGLAFGSGGFTELHSAGEFSHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHH
AGEIGVVLLLLLLGLEYTAAELVTGLRRSWAAGLFDLVANATPGALVALLLGWGFTGAIT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
MAGVTYISSSGIVAKVLNDLGRLGNRETPVILSILVFEDLAMAVYLPILTTILAGLSFFS
HHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMKALGIALVTVTLVLVVALRYGRYVSALVNSPDNEVFLLKLLGAALLVAGAASALNVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLLGIAISGSTAHQAVKLLEPLRDLFAAIFFVAFGLNTDPRAIPPVLGWAVALAVL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TTLTKIGTGWWAARRQGIRRMGRARAGAALVARGEFSIVIAGLAVTMGAVDGRLAALASA
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
YVLLMAVLGPVAARVVEPVAGFAQRRRAPAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SGTALGLLELGAVLFALGLLGRVAMRIGMSPIPLYLLGGLAFGSGGFTELHSAGEFSHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]