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The map label for this gene is pimA [H]

Identifier: 54025678

GI number: 54025678

Start: 3922326

End: 3923450

Strand: Reverse

Name: pimA [H]

Synonym: nfa37080

Alternate gene names: 54025678

Gene position: 3923450-3922326 (Counterclockwise)

Preceding gene: 54025679

Following gene: 54025677

Centisome position: 65.16

GC content: 71.47

Gene sequence:

>1125_bases
GTGAAGATCGGCATGGTCTGCCCCTACTCGTTCGACGTCCCCGGCGGCGTGCAGGCCCATGTGGTCGAGCTCGCGCGGGT
GTTCCTCGAGCGCGGCCACAAGGTGAGCGTGCTCGCCCCCGCCTCGGAGGGCACCCCGCTGCCGGACTTCGTGGTCTCGG
CCGGGCGCGCCGTCGCCATCCCGTACAACGGCTCGGTGGCCCGGCTGTCGTTCGGGCCGATGGCCTACACCCGCATCCGG
CGCTGGATCGACGGCAACGACTTCGACGTGCTGCACATCCACGAGCCGAACGCACCGAGCCTGTCGATGCTCGCGCTCAA
GATCGCCGAAGGTCCCATCGTGGCGACCTTCCACACCTCCACCACCCGGTCGCTGGTGCTGAGCACCTTCCAGGGCGTGC
TGCGGCCGTACCACGAGAAGATCAGCGGCCGCATCGCCGTGTCCGAGCTGGCGCGGCGCTGGCAGGTGGAGGCGCTGGGC
TCGGACGCGGTGGAGATCCCCAACGGCGTGGACGTGCCCGCCTTCGCCCGGGCACCGATGCTGCCCGGCTATCCGCGGCC
CGGCGGCACCGTGCTGTTTCTCGGCCGCTACGACGAGCCCCGCAAGGGCATGCAGGTGTTGCTGGCGGCGCTGCCCGAGC
TGGTCGCCCGGCACCCGGACGTGGAGATCCTGGTGGTCGGCCGCGGTGACGAGCAGCGACTGCGCCGGGAGGCGGGCAGG
CACGCCCGGCATCTGCGGTTCCTCGGCCAGGTCTCCGACGCGGAGAAGGCCTCGGCCATGCGCAGCGCCGACGTGTACGT
CGCGCCGAATCTCGGCGGGGAGAGCTTCGGCATCATCCTCATCGAGGCGATGGCCGCGGGCACGGCGGTGGTCGCCAGCG
AACTCGACGCGTTCCGCCGGGTGTTGCGCGACGGCACCGCGGGCATGCTGGTGCCGGTGGGCGACGATGTCGCGCTTGCC
GGTGCGCTCGACACCCTGCTCACCGACACCGAACGGCGGGAAGCCTTGGTGCGCAGGGCGAACCAGGTGGTGGGCGAATA
CGACTGGCCGGTGGTGGCCGAGCAGATCCTGCGCGTCTACGAAACCGTGACGGTCGGCGACACCCGGGTACGGGCGGCCG
GATGA

Upstream 100 bases:

>100_bases
TGCAGCCGCTGTGGGAGAGCGACCTGTCGCCGCAGCGGCTCGCCAGGATCGCCGAGGCGCAGGCGCGCCTGGCCGGACCG
GTGGGGAGGGACGAGTCCGC

Downstream 100 bases:

>100_bases
TCACCTTCTCCGCGACCACGGTTCTCGTCCTTGCGCTGATCGCGGCCGTCGTGCTGGCCGTCGGCGTGTGGGCCTACTCC
ACGGCCAATCGGCTCGACCG

Product: putative glycosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKIGMVCPYSFDVPGGVQAHVVELARVFLERGHKVSVLAPASEGTPLPDFVVSAGRAVAIPYNGSVARLSFGPMAYTRIR
RWIDGNDFDVLHIHEPNAPSLSMLALKIAEGPIVATFHTSTTRSLVLSTFQGVLRPYHEKISGRIAVSELARRWQVEALG
SDAVEIPNGVDVPAFARAPMLPGYPRPGGTVLFLGRYDEPRKGMQVLLAALPELVARHPDVEILVVGRGDEQRLRREAGR
HARHLRFLGQVSDAEKASAMRSADVYVAPNLGGESFGIILIEAMAAGTAVVASELDAFRRVLRDGTAGMLVPVGDDVALA
GALDTLLTDTERREALVRRANQVVGEYDWPVVAEQILRVYETVTVGDTRVRAAG

Sequences:

>Translated_374_residues
MKIGMVCPYSFDVPGGVQAHVVELARVFLERGHKVSVLAPASEGTPLPDFVVSAGRAVAIPYNGSVARLSFGPMAYTRIR
RWIDGNDFDVLHIHEPNAPSLSMLALKIAEGPIVATFHTSTTRSLVLSTFQGVLRPYHEKISGRIAVSELARRWQVEALG
SDAVEIPNGVDVPAFARAPMLPGYPRPGGTVLFLGRYDEPRKGMQVLLAALPELVARHPDVEILVVGRGDEQRLRREAGR
HARHLRFLGQVSDAEKASAMRSADVYVAPNLGGESFGIILIEAMAAGTAVVASELDAFRRVLRDGTAGMLVPVGDDVALA
GALDTLLTDTERREALVRRANQVVGEYDWPVVAEQILRVYETVTVGDTRVRAAG
>Mature_374_residues
MKIGMVCPYSFDVPGGVQAHVVELARVFLERGHKVSVLAPASEGTPLPDFVVSAGRAVAIPYNGSVARLSFGPMAYTRIR
RWIDGNDFDVLHIHEPNAPSLSMLALKIAEGPIVATFHTSTTRSLVLSTFQGVLRPYHEKISGRIAVSELARRWQVEALG
SDAVEIPNGVDVPAFARAPMLPGYPRPGGTVLFLGRYDEPRKGMQVLLAALPELVARHPDVEILVVGRGDEQRLRREAGR
HARHLRFLGQVSDAEKASAMRSADVYVAPNLGGESFGIILIEAMAAGTAVVASELDAFRRVLRDGTAGMLVPVGDDVALA
GALDTLLTDTERREALVRRANQVVGEYDWPVVAEQILRVYETVTVGDTRVRAAG

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to pimB, the mannosyltransferase pim

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 40423; Mature: 40423

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGMVCPYSFDVPGGVQAHVVELARVFLERGHKVSVLAPASEGTPLPDFVVSAGRAVAI
CCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCCEEEE
PYNGSVARLSFGPMAYTRIRRWIDGNDFDVLHIHEPNAPSLSMLALKIAEGPIVATFHTS
ECCCCEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECC
TTRSLVLSTFQGVLRPYHEKISGRIAVSELARRWQVEALGSDAVEIPNGVDVPAFARAPM
HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCCEECCCCCCCCCHHCCCC
LPGYPRPGGTVLFLGRYDEPRKGMQVLLAALPELVARHPDVEILVVGRGDEQRLRREAGR
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHH
HARHLRFLGQVSDAEKASAMRSADVYVAPNLGGESFGIILIEAMAAGTAVVASELDAFRR
HHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHH
VLRDGTAGMLVPVGDDVALAGALDTLLTDTERREALVRRANQVVGEYDWPVVAEQILRVY
HHHCCCCCEEEECCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ETVTVGDTRVRAAG
HHEEECCCEEEECC
>Mature Secondary Structure
MKIGMVCPYSFDVPGGVQAHVVELARVFLERGHKVSVLAPASEGTPLPDFVVSAGRAVAI
CCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCCEEEE
PYNGSVARLSFGPMAYTRIRRWIDGNDFDVLHIHEPNAPSLSMLALKIAEGPIVATFHTS
ECCCCEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECC
TTRSLVLSTFQGVLRPYHEKISGRIAVSELARRWQVEALGSDAVEIPNGVDVPAFARAPM
HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCCEECCCCCCCCCHHCCCC
LPGYPRPGGTVLFLGRYDEPRKGMQVLLAALPELVARHPDVEILVVGRGDEQRLRREAGR
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHH
HARHLRFLGQVSDAEKASAMRSADVYVAPNLGGESFGIILIEAMAAGTAVVASELDAFRR
HHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHH
VLRDGTAGMLVPVGDDVALAGALDTLLTDTERREALVRRANQVVGEYDWPVVAEQILRVY
HHHCCCCCEEEECCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ETVTVGDTRVRAAG
HHEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12068013 [H]