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The map label for this gene is ribE [H]

Identifier: 54025571

GI number: 54025571

Start: 3812958

End: 3813581

Strand: Reverse

Name: ribE [H]

Synonym: nfa36010

Alternate gene names: 54025571

Gene position: 3813581-3812958 (Counterclockwise)

Preceding gene: 54025573

Following gene: 54025570

Centisome position: 63.34

GC content: 69.55

Gene sequence:

>624_bases
ATGTTCACAGGCATCGTCGAGGAACTGGGCGAGATCGTCGCCGTGGCACGGCTGGCGGACGCCGCCCGGCTGACGATCCG
GGGCAAGCTCGTGACTTCCGATGCCGGGCACGGCGATTCGATCGCGGTCAACGGCGTGTGCCTGACCGTCGTGGACGTGC
TCGACGGCGACTCCTTCACCGTCGACGTGATGCAGGAGACCCTCGACCGCTCCAGCATCGGCGGCCTCGAAGCAGGCGCC
CGGGTGAACCTGGAGCGGGCCGCCGCGCTGAACAGCCGCCTCGGCGGCCACCTGGTGCAGGGGCACGTCGACGGCACCGG
CACGGTGCTGGCGCGCACCCCCTCGGAGAACTGGGAGGTCGTGCGGATCTCGCTGCCCGACGCGATCGCCCGCTACGTGG
TGGAGAAGGGTTCGATCACCGTCGACGGCATCTCCCTCACCGTCTCCGGGCTCGGCCGCAGTGAGCAGCCCGCCACCGAC
GGTAACCGTGACTGGTTCGAGGTCTCGCTGATCCCCACCACCCTCTCGCTGACCAACCTCGGCAGCGCGGCCGTCGGCAC
CCGGGTGAACCTGGAGGTCGACGTGATCGCCAAGTACGTCGAGCGCCTGCAACAGCGAGGCTGA

Upstream 100 bases:

>100_bases
CTTCCGCACCCGTCGTTAGGCTGACGAGCGAACCGATGCGGGGAATAGCGGCCACGGCGGCGCTGTTCCGCCAGGTAATC
AGACGCGACAGGAGTCAGGG

Downstream 100 bases:

>100_bases
CCGGCGGCACCCACCGCTGGGACGGCCCGGCCGTCCCAGACCTTCCGAACGGTAGGAAGCCGGAAGCCCGTGCGTCCACC
GGGCGACTCGCAGGGGGCGC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFTGIVEELGEIVAVARLADAARLTIRGKLVTSDAGHGDSIAVNGVCLTVVDVLDGDSFTVDVMQETLDRSSIGGLEAGA
RVNLERAAALNSRLGGHLVQGHVDGTGTVLARTPSENWEVVRISLPDAIARYVVEKGSITVDGISLTVSGLGRSEQPATD
GNRDWFEVSLIPTTLSLTNLGSAAVGTRVNLEVDVIAKYVERLQQRG

Sequences:

>Translated_207_residues
MFTGIVEELGEIVAVARLADAARLTIRGKLVTSDAGHGDSIAVNGVCLTVVDVLDGDSFTVDVMQETLDRSSIGGLEAGA
RVNLERAAALNSRLGGHLVQGHVDGTGTVLARTPSENWEVVRISLPDAIARYVVEKGSITVDGISLTVSGLGRSEQPATD
GNRDWFEVSLIPTTLSLTNLGSAAVGTRVNLEVDVIAKYVERLQQRG
>Mature_207_residues
MFTGIVEELGEIVAVARLADAARLTIRGKLVTSDAGHGDSIAVNGVCLTVVDVLDGDSFTVDVMQETLDRSSIGGLEAGA
RVNLERAAALNSRLGGHLVQGHVDGTGTVLARTPSENWEVVRISLPDAIARYVVEKGSITVDGISLTVSGLGRSEQPATD
GNRDWFEVSLIPTTLSLTNLGSAAVGTRVNLEVDVIAKYVERLQQRG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=196, Percent_Identity=36.2244897959184, Blast_Score=110, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=211, Percent_Identity=38.8625592417062, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21778; Mature: 21778

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEELGEIVAVARLADAARLTIRGKLVTSDAGHGDSIAVNGVCLTVVDVLDGDSFT
CCCHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCCEEECCEEEEEEEECCCCCEE
VDVMQETLDRSSIGGLEAGARVNLERAAALNSRLGGHLVQGHVDGTGTVLARTPSENWEV
HHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCEE
VRISLPDAIARYVVEKGSITVDGISLTVSGLGRSEQPATDGNRDWFEVSLIPTTLSLTNL
EEEECCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEECCC
GSAAVGTRVNLEVDVIAKYVERLQQRG
CCCCCCCEEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTGIVEELGEIVAVARLADAARLTIRGKLVTSDAGHGDSIAVNGVCLTVVDVLDGDSFT
CCCHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCCEEECCEEEEEEEECCCCCEE
VDVMQETLDRSSIGGLEAGARVNLERAAALNSRLGGHLVQGHVDGTGTVLARTPSENWEV
HHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCEE
VRISLPDAIARYVVEKGSITVDGISLTVSGLGRSEQPATDGNRDWFEVSLIPTTLSLTNL
EEEECCHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEECCC
GSAAVGTRVNLEVDVIAKYVERLQQRG
CCCCCCCEEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]