Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 54025559

GI number: 54025559

Start: 3799309

End: 3800328

Strand: Reverse

Name: gap [H]

Synonym: nfa35890

Alternate gene names: 54025559

Gene position: 3800328-3799309 (Counterclockwise)

Preceding gene: 54025561

Following gene: 54025558

Centisome position: 63.12

GC content: 66.47

Gene sequence:

>1020_bases
GTGACTGTCCGGGTAGGCATCAACGGCTTCGGTCGTATCGGACGTAACTTCTTCCGGGCGGTGGAGGCGCAGAAGGCGCT
GGGCACCACCGACATCGAGATCGTCGCGGTCAACGACCTCACCGACAACGCGACCCTGGCCACGCTGCTGAAGTACGACT
CGATCCTCGGCCGCCTGCCGAAGGACGTCTCGCTCGACGGCGACGACACCATCGTGGTCGGCGACCAGCGGATCAAGGCG
CTGGCCATCAAGGAGGGCCCCGCCGCCCTGCCGTGGGGCGACCTCGGCGTCGACGTGGTCGTCGAGTCCACCGGCATCTT
CACCGATGCCACCAAGGCCAAGGGCCACCTGGCCGCGGGCGCCAAGAAGGTCATCATCTCGGCCCCGGCCAAGGGCGAGG
ACATCACCATCGTGATGGGCGTCAACGACGACAAGTACGACGGCAGCCAGAACATCATCTCCAACGCGTCCTGCACCACC
AACTGCCTGGGCCCGCTGGCGAAGGTGCTCAACGACGAGTTCGGCATCGTCAAGGGCCTGATGACCACCATCCACGCCTA
CACCCAGGACCAGAACCTGCAGGACGGCCCGCACAAGGACCTGCGTCGCGCCCGCGCCGCCGCGGTGAACATCGTGCCGA
CCAGCACCGGCGCGGCCAAGGCCATCGGCCTGGTGCTGCCCGAGCTCAACGGCAAGCTCGACGGCTACTCGCTGCGCGTG
CCGATCCCCACCGGCTCGATCACCGACCTGACCGCCGACCTGGCCAAGAAGGCGACGGTCGAGGAGATCAACGCGGCGTT
CAAGGCGGCCGCGGAGGGCCCACTGAAGGGCATCCTGAAGTACAGCGTCGACCCGATCGTCTCCAGCGACATCGTCACCG
ACCCGCACTCCTCGATCTTCGACGCGCCGCTGACCAAGGTCATCGACGATCAGGTGAAGGTCTACTCCTGGTACGACAAC
GAGTGGGGCTACTCCAACCGCCTCGCCGACCTCATCGGCCTCGTCGGCAAGTCCCTCTGA

Upstream 100 bases:

>100_bases
GCGCTCACGAATCCCAGGTGGTTGTCGGAGAGATCCGCGGCTGGGATTAGTGTGGGTACGGCATCGGAATGAATCCGCTT
GAAAGCTGAGGAGCGATAAC

Downstream 100 bases:

>100_bases
TCACATGGCTGTCAAGACACTCCAGGATCTCCTGAACGAGGGTGTCGAAGGTCGGGGCGTGCTGGTGCGCTCCGACCTGA
ACGTCCCCCTCGACGACAAC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTVRVGINGFGRIGRNFFRAVEAQKALGTTDIEIVAVNDLTDNATLATLLKYDSILGRLPKDVSLDGDDTIVVGDQRIKA
LAIKEGPAALPWGDLGVDVVVESTGIFTDATKAKGHLAAGAKKVIISAPAKGEDITIVMGVNDDKYDGSQNIISNASCTT
NCLGPLAKVLNDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAAVNIVPTSTGAAKAIGLVLPELNGKLDGYSLRV
PIPTGSITDLTADLAKKATVEEINAAFKAAAEGPLKGILKYSVDPIVSSDIVTDPHSSIFDAPLTKVIDDQVKVYSWYDN
EWGYSNRLADLIGLVGKSL

Sequences:

>Translated_339_residues
MTVRVGINGFGRIGRNFFRAVEAQKALGTTDIEIVAVNDLTDNATLATLLKYDSILGRLPKDVSLDGDDTIVVGDQRIKA
LAIKEGPAALPWGDLGVDVVVESTGIFTDATKAKGHLAAGAKKVIISAPAKGEDITIVMGVNDDKYDGSQNIISNASCTT
NCLGPLAKVLNDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAAVNIVPTSTGAAKAIGLVLPELNGKLDGYSLRV
PIPTGSITDLTADLAKKATVEEINAAFKAAAEGPLKGILKYSVDPIVSSDIVTDPHSSIFDAPLTKVIDDQVKVYSWYDN
EWGYSNRLADLIGLVGKSL
>Mature_338_residues
TVRVGINGFGRIGRNFFRAVEAQKALGTTDIEIVAVNDLTDNATLATLLKYDSILGRLPKDVSLDGDDTIVVGDQRIKAL
AIKEGPAALPWGDLGVDVVVESTGIFTDATKAKGHLAAGAKKVIISAPAKGEDITIVMGVNDDKYDGSQNIISNASCTTN
CLGPLAKVLNDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAAVNIVPTSTGAAKAIGLVLPELNGKLDGYSLRVP
IPTGSITDLTADLAKKATVEEINAAFKAAAEGPLKGILKYSVDPIVSSDIVTDPHSSIFDAPLTKVIDDQVKVYSWYDNE
WGYSNRLADLIGLVGKSL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=50.4504504504504, Blast_Score=306, Evalue=1e-83,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=49.3975903614458, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1788079, Length=339, Percent_Identity=54.2772861356932, Blast_Score=340, Evalue=9e-95,
Organism=Escherichia coli, GI1789295, Length=332, Percent_Identity=42.7710843373494, Blast_Score=271, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=53.3923303834808, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=53.3923303834808, Blast_Score=326, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=51.9174041297935, Blast_Score=313, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=51.9174041297935, Blast_Score=313, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=52.5073746312684, Blast_Score=320, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=51.622418879056, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=51.0324483775811, Blast_Score=315, Evalue=6e-87,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=50.9036144578313, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=50.9036144578313, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=50.9036144578313, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=50.9036144578313, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=48.3483483483483, Blast_Score=291, Evalue=6e-79,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35868; Mature: 35737

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVGINGFGRIGRNFFRAVEAQKALGTTDIEIVAVNDLTDNATLATLLKYDSILGRLP
CEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCC
KDVSLDGDDTIVVGDQRIKALAIKEGPAALPWGDLGVDVVVESTGIFTDATKAKGHLAAG
CCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCEECCCCCCCCHHCC
AKKVIISAPAKGEDITIVMGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFGIVKGL
CEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHHHHHHH
MTTIHAYTQDQNLQDGPHKDLRRARAAAVNIVPTSTGAAKAIGLVLPELNGKLDGYSLRV
HHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEECCCCCHHHHEEEECCCCCCCCCEEEEE
PIPTGSITDLTADLAKKATVEEINAAFKAAAEGPLKGILKYSVDPIVSSDIVTDPHSSIF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHH
DAPLTKVIDDQVKVYSWYDNEWGYSNRLADLIGLVGKSL
HHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVRVGINGFGRIGRNFFRAVEAQKALGTTDIEIVAVNDLTDNATLATLLKYDSILGRLP
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCC
KDVSLDGDDTIVVGDQRIKALAIKEGPAALPWGDLGVDVVVESTGIFTDATKAKGHLAAG
CCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCEECCCCCCCCHHCC
AKKVIISAPAKGEDITIVMGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFGIVKGL
CEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHHHHHHH
MTTIHAYTQDQNLQDGPHKDLRRARAAAVNIVPTSTGAAKAIGLVLPELNGKLDGYSLRV
HHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEECCCCCHHHHEEEECCCCCCCCCEEEEE
PIPTGSITDLTADLAKKATVEEINAAFKAAAEGPLKGILKYSVDPIVSSDIVTDPHSSIF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHH
DAPLTKVIDDQVKVYSWYDNEWGYSNRLADLIGLVGKSL
HHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA