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The map label for this gene is kstR2 [H]

Identifier: 54025516

GI number: 54025516

Start: 3758617

End: 3759210

Strand: Reverse

Name: kstR2 [H]

Synonym: nfa35460

Alternate gene names: 54025516

Gene position: 3759210-3758617 (Counterclockwise)

Preceding gene: 54025517

Following gene: 54025515

Centisome position: 62.43

GC content: 68.18

Gene sequence:

>594_bases
ATGGGAGCCGAGCCGAACAACGGGCGCAAGGTCATCCTGGACTCCGCCCTGCGCAACATGACCGAGCGCGGCTATCACGG
CACCTCCATGCGCGACATCGCCCGCGACGCCGACATCACCGTGGCCTCGATCTACCACCATTTCAAGTCCAAGCAGGAAA
TCCTGCAGGACATCATGATTCGCGCGCTGCACGACGCGATCGCCATGACCCGCAACGCGTTGCTGCGCGCGGGCGCCACC
CCGGCCGACCAGCTGCGGGCGATCATGCGCGCGTGGATCATGTTCCACACCACCCGGCAGTCGGATGCGCTGGTGGGCGC
GACCGAGCTGCGCAGCCTCGACTACGAGGGTCGCCGACTCATCGTCGCGCTGCGTGACGAGCAGGAGCACATCTTCCGCG
ACGTCATCGACCGGGGGATCGAGGAGGGCGCCTTCGCGACGTCGCTGCCGCGCGACGCCGCGCGGGCGATCATCAACATG
GGTCAGTCGGTGTGCACCTGGTGGCGTCCGGACGGGCCGCTGCGGCCCGAGGAACTCGCGGACCGGTACGCGGAACTGGC
GCTGGCGATGGTCGAGCCGGTCGATTCGCGATAG

Upstream 100 bases:

>100_bases
CCGCGGGCATCAGCGCCTGAATCCCGGCCGCGCGGGCGGACGCCGTGGCAGCCGATACGCTGTGCACTTTCGGGCAGTCG
AACGGGAAACGGGTGAGCGC

Downstream 100 bases:

>100_bases
TCCTGCGCCTCGCCGCAGCGCGTCCCGACGCTCGATCGGGTAGCGACGGTGCCGCGTGTGCGGCCGTCGCCGTTCGGGCC
TCTCCGGAAGCCGAGACCTG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MGAEPNNGRKVILDSALRNMTERGYHGTSMRDIARDADITVASIYHHFKSKQEILQDIMIRALHDAIAMTRNALLRAGAT
PADQLRAIMRAWIMFHTTRQSDALVGATELRSLDYEGRRLIVALRDEQEHIFRDVIDRGIEEGAFATSLPRDAARAIINM
GQSVCTWWRPDGPLRPEELADRYAELALAMVEPVDSR

Sequences:

>Translated_197_residues
MGAEPNNGRKVILDSALRNMTERGYHGTSMRDIARDADITVASIYHHFKSKQEILQDIMIRALHDAIAMTRNALLRAGAT
PADQLRAIMRAWIMFHTTRQSDALVGATELRSLDYEGRRLIVALRDEQEHIFRDVIDRGIEEGAFATSLPRDAARAIINM
GQSVCTWWRPDGPLRPEELADRYAELALAMVEPVDSR
>Mature_196_residues
GAEPNNGRKVILDSALRNMTERGYHGTSMRDIARDADITVASIYHHFKSKQEILQDIMIRALHDAIAMTRNALLRAGATP
ADQLRAIMRAWIMFHTTRQSDALVGATELRSLDYEGRRLIVALRDEQEHIFRDVIDRGIEEGAFATSLPRDAARAIINMG
QSVCTWWRPDGPLRPEELADRYAELALAMVEPVDSR

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22239; Mature: 22107

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAEPNNGRKVILDSALRNMTERGYHGTSMRDIARDADITVASIYHHFKSKQEILQDIMI
CCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RALHDAIAMTRNALLRAGATPADQLRAIMRAWIMFHTTRQSDALVGATELRSLDYEGRRL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEE
IVALRDEQEHIFRDVIDRGIEEGAFATSLPRDAARAIINMGQSVCTWWRPDGPLRPEELA
EEEECCCHHHHHHHHHHCCHHCCCHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCHHHHH
DRYAELALAMVEPVDSR
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GAEPNNGRKVILDSALRNMTERGYHGTSMRDIARDADITVASIYHHFKSKQEILQDIMI
CCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RALHDAIAMTRNALLRAGATPADQLRAIMRAWIMFHTTRQSDALVGATELRSLDYEGRRL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEE
IVALRDEQEHIFRDVIDRGIEEGAFATSLPRDAARAIINMGQSVCTWWRPDGPLRPEELA
EEEECCCHHHHHHHHHHCCHHCCCHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCHHHHH
DRYAELALAMVEPVDSR
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]