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The map label for this gene is fadE33 [H]

Identifier: 54025514

GI number: 54025514

Start: 3756022

End: 3757251

Strand: Reverse

Name: fadE33 [H]

Synonym: nfa35440

Alternate gene names: 54025514

Gene position: 3757251-3756022 (Counterclockwise)

Preceding gene: 54025515

Following gene: 54025513

Centisome position: 62.4

GC content: 72.36

Gene sequence:

>1230_bases
ATGGATTTCGCATACAGCCACACCGTCGAACAGCTCCGGGCTCAGCTCGTCACGTTCCTCCAGGACGTCGTGCTACCCGC
CGAACCGGTCGCCGCCGCCCAACTCGCCGCCGCGCCGGAACATTGGGGCGCACCGCCGGTGCTGGCCGACCTCAAGGACG
AGGCCAAGCGGGCCGGACTGTGGAACCTCTTCCTGCCACCGCACGAGGACGGCGGCCTGACCCACCTCGAGTACGCCCCG
CTCGCCGAGCTGACCGGGTGGAGCCCCCAGCTCGCGCCCGAGGCCCTCAACTGCAGCCCGCCCGACACCGGCAACATGGA
ACTGCTGCTGCGCTACGGCACCGACGAACAGCGGCGGCGCTGGCTCGATCCACTGCTCGACGGCGCCATCCGGTCCTGCT
TCGCGATGACCGAACCCGACGTCGCCAGCTCCGACGCCAACAACATCCGCCTCGAGATCGCCGACGCGGGGGAGCACTGG
GTGCTCACCGGGCACAAGTGGTGGACGACGGCCGCCCTGCGCGCGGACAACGCGGTCGCGCTGGTCATGGGCGTCACCGA
CCCCGGCGCGCCGGTCGGAGCGCGGCACTCGATCGTGTTGGTGCCGATGGACACCCCGGGTGTCACCGTCGAACGGTCCA
CCACCGTCCTCGGATTCGACGACCGCCACGAGGGCGGGCACGGGGTGCTCGCGTTCGACGGTGCGCGCGTACCGAAGGCG
AACCTGCTCGGCCCCCGCGGCAAGGGATTCGCCGTCGCGCAGGCCCGGCTGGGCCCGGGCCGGATCCACCACTGCATGCG
GCTGATCGGCATGGGCGAGCGCGCCATCGCGCTGATGACCCGGCGAGCGCGCGATCGGGTCGCCTTCGGGGTTCCGCTGG
CCGACGAGGGCGTCGTGCAGGCGACGATCGCCGACGCCAGGATCGCCGTGGACGCCGCCCGGCTCATGGTGCTGCGCGCC
GCCTGGCGGATGGACGTGGCGGGCGCCAAGGCCGCCCGCCACGACATCGCCGCGGCCAAGGTCCTCGTTCCGCGCACCAT
CAAGGGCGTCGTCGACGAGGCCATCCAGATCTTCGGGGGCGCCGGCCTGGCCCAGGACACCCCGCTGGCGATGCTGTACG
CCCAGGCCAGATACCTGCAGATCGCCGACGGTCCCGATCAGGTACACCGCCGCTCGCTCGCCCGCGCCGAACTCGCCGCC
ACCCCGGACCTCCGCGAGACCCCCTCCTGA

Upstream 100 bases:

>100_bases
ATGGTCGGCCCGCTTTTGCGCCGCGCGCTGGATCTGGCCGCCGCCTCCGACCTTCCCGGGCCGCGGCGCTGACACGCCCC
GGCGAATCGAAAGAACCCCC

Downstream 100 bases:

>100_bases
ATCACCCGGCATCCCAGGCGATGCCGCCGTTCGCCCCATCCAGAATCGAGTACAGCCATGACCCCTCGGACCGACAGCGT
CGCGGTCTCCGCCACCCCCG

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDFAYSHTVEQLRAQLVTFLQDVVLPAEPVAAAQLAAAPEHWGAPPVLADLKDEAKRAGLWNLFLPPHEDGGLTHLEYAP
LAELTGWSPQLAPEALNCSPPDTGNMELLLRYGTDEQRRRWLDPLLDGAIRSCFAMTEPDVASSDANNIRLEIADAGEHW
VLTGHKWWTTAALRADNAVALVMGVTDPGAPVGARHSIVLVPMDTPGVTVERSTTVLGFDDRHEGGHGVLAFDGARVPKA
NLLGPRGKGFAVAQARLGPGRIHHCMRLIGMGERAIALMTRRARDRVAFGVPLADEGVVQATIADARIAVDAARLMVLRA
AWRMDVAGAKAARHDIAAAKVLVPRTIKGVVDEAIQIFGGAGLAQDTPLAMLYAQARYLQIADGPDQVHRRSLARAELAA
TPDLRETPS

Sequences:

>Translated_409_residues
MDFAYSHTVEQLRAQLVTFLQDVVLPAEPVAAAQLAAAPEHWGAPPVLADLKDEAKRAGLWNLFLPPHEDGGLTHLEYAP
LAELTGWSPQLAPEALNCSPPDTGNMELLLRYGTDEQRRRWLDPLLDGAIRSCFAMTEPDVASSDANNIRLEIADAGEHW
VLTGHKWWTTAALRADNAVALVMGVTDPGAPVGARHSIVLVPMDTPGVTVERSTTVLGFDDRHEGGHGVLAFDGARVPKA
NLLGPRGKGFAVAQARLGPGRIHHCMRLIGMGERAIALMTRRARDRVAFGVPLADEGVVQATIADARIAVDAARLMVLRA
AWRMDVAGAKAARHDIAAAKVLVPRTIKGVVDEAIQIFGGAGLAQDTPLAMLYAQARYLQIADGPDQVHRRSLARAELAA
TPDLRETPS
>Mature_409_residues
MDFAYSHTVEQLRAQLVTFLQDVVLPAEPVAAAQLAAAPEHWGAPPVLADLKDEAKRAGLWNLFLPPHEDGGLTHLEYAP
LAELTGWSPQLAPEALNCSPPDTGNMELLLRYGTDEQRRRWLDPLLDGAIRSCFAMTEPDVASSDANNIRLEIADAGEHW
VLTGHKWWTTAALRADNAVALVMGVTDPGAPVGARHSIVLVPMDTPGVTVERSTTVLGFDDRHEGGHGVLAFDGARVPKA
NLLGPRGKGFAVAQARLGPGRIHHCMRLIGMGERAIALMTRRARDRVAFGVPLADEGVVQATIADARIAVDAARLMVLRA
AWRMDVAGAKAARHDIAAAKVLVPRTIKGVVDEAIQIFGGAGLAQDTPLAMLYAQARYLQIADGPDQVHRRSLARAELAA
TPDLRETPS

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI48976061, Length=397, Percent_Identity=53.4005037783375, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI211971008, Length=402, Percent_Identity=52.9850746268657, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI38505218, Length=400, Percent_Identity=45.5, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI4557233, Length=330, Percent_Identity=33.030303030303, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4557231, Length=399, Percent_Identity=25.31328320802, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI187960098, Length=399, Percent_Identity=25.31328320802, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=26.4550264550265, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4501859, Length=305, Percent_Identity=27.5409836065574, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI21361497, Length=346, Percent_Identity=26.0115606936416, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=27.0348837209302, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI226958412, Length=397, Percent_Identity=26.1964735516373, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4557235, Length=344, Percent_Identity=27.0348837209302, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226958414, Length=289, Percent_Identity=27.3356401384083, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI4501857, Length=404, Percent_Identity=25.2475247524752, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI7669494, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503943, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=286, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786223, Length=296, Percent_Identity=24.6621621621622, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=390, Percent_Identity=44.3589743589744, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17534899, Length=405, Percent_Identity=28.3950617283951, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=405, Percent_Identity=27.1604938271605, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=291, Percent_Identity=29.553264604811, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=293, Percent_Identity=29.3515358361775, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=28.080229226361, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=263, Percent_Identity=30.4182509505703, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=297, Percent_Identity=28.2828282828283, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=288, Percent_Identity=27.4305555555556, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=293, Percent_Identity=27.6450511945392, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=296, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=242, Percent_Identity=28.099173553719, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356377, Length=332, Percent_Identity=31.6265060240964, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24660351, Length=402, Percent_Identity=28.3582089552239, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281363737, Length=359, Percent_Identity=28.133704735376, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24646207, Length=291, Percent_Identity=27.4914089347079, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24666513, Length=291, Percent_Identity=27.1477663230241, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355753, Length=289, Percent_Identity=25.9515570934256, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920834, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43915; Mature: 43915

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFAYSHTVEQLRAQLVTFLQDVVLPAEPVAAAQLAAAPEHWGAPPVLADLKDEAKRAGL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHCCCCCHHHHHHHHHHHCCE
WNLFLPPHEDGGLTHLEYAPLAELTGWSPQLAPEALNCSPPDTGNMELLLRYGTDEQRRR
EEEECCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHH
WLDPLLDGAIRSCFAMTEPDVASSDANNIRLEIADAGEHWVLTGHKWWTTAALRADNAVA
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEECCCEEEEEEEECCCEEE
LVMGVTDPGAPVGARHSIVLVPMDTPGVTVERSTTVLGFDDRHEGGHGVLAFDGARVPKA
EEEECCCCCCCCCCCCEEEEEECCCCCEEEECCEEEEECCCCCCCCCEEEEECCCCCCCC
NLLGPRGKGFAVAQARLGPGRIHHCMRLIGMGERAIALMTRRARDRVAFGVPLADEGVVQ
CCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCEEE
ATIADARIAVDAARLMVLRAAWRMDVAGAKAARHDIAAAKVLVPRTIKGVVDEAIQIFGG
EEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGLAQDTPLAMLYAQARYLQIADGPDQVHRRSLARAELAATPDLRETPS
CCCCCCCCHHHEEEHHEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDFAYSHTVEQLRAQLVTFLQDVVLPAEPVAAAQLAAAPEHWGAPPVLADLKDEAKRAGL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHCCCCCHHHHHHHHHHHCCE
WNLFLPPHEDGGLTHLEYAPLAELTGWSPQLAPEALNCSPPDTGNMELLLRYGTDEQRRR
EEEECCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHH
WLDPLLDGAIRSCFAMTEPDVASSDANNIRLEIADAGEHWVLTGHKWWTTAALRADNAVA
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEECCCEEEEEEEECCCEEE
LVMGVTDPGAPVGARHSIVLVPMDTPGVTVERSTTVLGFDDRHEGGHGVLAFDGARVPKA
EEEECCCCCCCCCCCCEEEEEECCCCCEEEECCEEEEECCCCCCCCCEEEEECCCCCCCC
NLLGPRGKGFAVAQARLGPGRIHHCMRLIGMGERAIALMTRRARDRVAFGVPLADEGVVQ
CCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCEEE
ATIADARIAVDAARLMVLRAAWRMDVAGAKAARHDIAAAKVLVPRTIKGVVDEAIQIFGG
EEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGLAQDTPLAMLYAQARYLQIADGPDQVHRRSLARAELAATPDLRETPS
CCCCCCCCHHHEEEHHEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]