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The map label for this gene is cysS

Identifier: 54020642

GI number: 54020642

Start: 833567

End: 834781

Strand: Reverse

Name: cysS

Synonym: mhp661

Alternate gene names: 54020642

Gene position: 834781-833567 (Counterclockwise)

Preceding gene: 54020643

Following gene: 54020641

Centisome position: 93.51

GC content: 25.27

Gene sequence:

>1215_bases
ATGAACTTAATTAATAAAAAAAATTTAAATATCTATCTTTGCGGGCCAACAGTTTATAGCGATGTTCATATTGGAAATTT
AAGAACTATAATTATTTTTGATGCTATTTTTGAATGTTTGAAAAACAAAGGTTTTTCGATAAATTTTTTACATAATATCA
CAGATATTGATGATAAAATTATTGAAAAAGCACAAGAATTAGGCATTTCTGAGGCTGAGCTAACAGAAAAATATACTAAC
GAATATTTTAAAATTTTAGAAATTTTTAATATAAAAAAACCAACAAAAATTGTTAAGGTGACCGAAAAAATAGAAAAAAT
TATAGAATATATAAAACTTTTAGAAAAAAAGGGATTTACATATTATAACAAAAACAACGACTTGGTTTTTGACATATTAA
AAATTCCTAATTACGGAATAATTTCTGGTCAAAAAATAGAATCATTACTGGATAAAAATACTAAAAAAACAAAGTCAAAA
AATGACTTTGTTTTATGAAAAAAAACCCAAAAAGGCTTGTTTTTTAAGTCTTTTTTCGGTTTAGGCCGACCTGGTTGACA
TACTGAATGTGCAGCACTTATCTATGATTATTTTCAAAAAAAATCACTTGATCTTCATGGTGGCGGGGTTGACTTAATTT
TTCCTCATCACGAAAACGAAAATGCTCAACATTTTGCTCTAACGGGAAATCCAATTGCCGAAAACTGGTTTCGCTCTGGG
TTTGTTAATTTAAATGGAAAAAAAATGGCCAAATCTTTGAATAATGTACTATTGGCAAAGGATTTTTCGCATAAATATAA
TCCAGATATTATTAGAAGTATTTTTTTGTCAATAAACCCAACAGTTCCAATCAATTTAACGGAAGAATTAATTAAAAATC
ATAAAAAATTAATCGAAAAATACCAAAAGATTTGTTTTGAGTGATATTTTGATAAAAAAAACGAAAAGACTGAAAAAGTT
GAACAAGTGCTTAATTTATTTATTGAGGGCAAATTCGCAAAAGCTAATTTTTTAATTATGGAATTAATAAAACAAAAAGA
AAATTCAACTATAAGAAAAATTTTTCTAAATTTAAGATTTAATTTCACAAAAATGCATTTAAACCCCGAAAGTCAGGAAA
AAATCAAAAATTGAAACAAATTAATTATGGATAAAAACTATTCCGAGGCCGATAAAATCCGTAAAGAATTATGAAAAATA
TTTAAAAATTCATAA

Upstream 100 bases:

>100_bases
CTTGTGCACCATTTTTTTAGCAAGCATAATAAACTTTTTTGGGAAAAAGTAGCTGAAATTATTCCTAATTATAAGGAATT
AATTAGAAAATTAAATGATT

Downstream 100 bases:

>100_bases
TTTTTTCCATCTTCCTTTTGAAAGATTGAAAGTATGGTTAAATATATTTGTGGCAGAAATTCATTAGCCGACGCGATCAA
GAATGGGTTTATTTTTAAGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTN
EYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSK
NDFVLWKKTQKGLFFKSFFGLGRPGWHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSG
FVNLNGKKMAKSLNNVLLAKDFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFEWYFDKKNEKTEKV
EQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMHLNPESQEKIKNWNKLIMDKNYSEADKIRKELWKI
FKNS

Sequences:

>Translated_404_residues
MNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTN
EYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSK
NDFVL*KKTQKGLFFKSFFGLGRPG*HTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSG
FVNLNGKKMAKSLNNVLLAKDFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFE*YFDKKNEKTEKV
EQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMHLNPESQEKIKN*NKLIMDKNYSEADKIRKEL*KI
FKNS
>Mature_404_residues
MNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTN
EYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSK
NDFVL*KKTQKGLFFKSFFGLGRPG*HTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSG
FVNLNGKKMAKSLNNVLLAKDFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFE*YFDKKNEKTEKV
EQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMHLNPESQEKIKN*NKLIMDKNYSEADKIRKEL*KI
FKNS

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=276, Percent_Identity=35.8695652173913, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI303304987, Length=227, Percent_Identity=29.5154185022026, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI21269877, Length=227, Percent_Identity=29.5154185022026, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI10835051, Length=227, Percent_Identity=29.5154185022026, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI62240992, Length=227, Percent_Identity=29.5154185022026, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1786737, Length=306, Percent_Identity=34.640522875817, Blast_Score=185, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17509797, Length=231, Percent_Identity=31.1688311688312, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17509795, Length=231, Percent_Identity=31.1688311688312, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324082, Length=220, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI19922218, Length=308, Percent_Identity=32.1428571428571, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI19922364, Length=255, Percent_Identity=28.2352941176471, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 46469; Mature: 46469

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKI
CCCCCCCCCEEEEECCCEECCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
IEKAQELGISEAELTEKYTNEYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
YYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDFVLKKTQKGLFFKSFFGL
EEECCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHCCCCCCEEEEHHCCCHHHHHHHCC
GRPGHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFV
CCCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHCCCC
NLNGKKMAKSLNNVLLAKDFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQ
CCCHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
KICFEYFDKKNEKTEKVEQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFT
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHEEEEEE
KMHLNPESQEKIKNNKLIMDKNYSEADKIRKELKIFKNS
EEEECCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKI
CCCCCCCCCEEEEECCCEECCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
IEKAQELGISEAELTEKYTNEYFKILEIFNIKKPTKIVKVTEKIEKIIEYIKLLEKKGFT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
YYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSKNDFVLKKTQKGLFFKSFFGL
EEECCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHCCCCCCEEEEHHCCCHHHHHHHCC
GRPGHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFV
CCCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHCCCC
NLNGKKMAKSLNNVLLAKDFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQ
CCCHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
KICFEYFDKKNEKTEKVEQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFT
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHEEEEEE
KMHLNPESQEKIKNNKLIMDKNYSEADKIRKELKIFKNS
EEEECCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA