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The map label for this gene is mtlD

Identifier: 54020587

GI number: 54020587

Start: 717925

End: 719028

Strand: Reverse

Name: mtlD

Synonym: mhp568

Alternate gene names: 54020587

Gene position: 719028-717925 (Counterclockwise)

Preceding gene: 54020588

Following gene: 54020586

Centisome position: 80.54

GC content: 25.63

Gene sequence:

>1104_bases
ATGAAAGTGGTTCATTTTGGCGCCGGAAATATCGGGCGCGGGTTGATTGCAAAACTATACCATCAAAATCAATTTGAAAT
TATTTTTGTCGATGTTAATCAAAATTTGGTTAATGATTTGAATAAGAACGGTTTTTATTATGTCATTAATTTTGAAAATG
GTGAAAAATATAAAATAACTAATTTTCAAGCAATCCATTTAAATAACAAGGAAAATTTATTAAAAAAATTAAGTTCAGCT
GATATTATTTCAACCTCAATCGGCGCAAAAAACTTGGTTTTTCTTAAATCAATTTTTGCAAAATTAGCAAAAATTGAAGA
AAAACATAAGCAAATTATTTGCTTTGAAAATGGTTATAGAGTAAGTTCTTATTTTAAGACTATTTTGGAAAAGTGCCAAT
TTTGAAACTTTGTTGATACAACAATTGACCAAATCGCGCCAAGTTCAAATGATTTAAACGTTTATACAGAAACATTTTCA
GAAATTATTTTAGAGGAAAAGCAACAAAAAATTAAGCTAAAAACTGTTGAATATTTGGAAAATCTCGATTTTTTTATTCT
TAGAAAGTTGTTTTTTGTCAATGCCTTACACTCAGGAATTGCCTATTTTGCTTATAATTTAAAGTTTAATTTTATTAATG
AGGCCCTAAATTCCGTCATAATTCAAAATTATATTGAAAAAATGAAGGAAGTTTTACAACAGACAGTTTTGATTATAAAT
CCCTTAATAGAACAAAAAATAATGAATGAATATTTTGAAACCACAATAAAAAGGTTCAAAAATCCCGTTTTGCAAGATTT
AGTTGTGCGAGTTGCAAGAAATCCTATTACAAAAATTTCAAAAAACGAAAGATTTGATTTGTTATTAAAATATGCAAAAA
AATCGAAAATATCATCTGAAAAGTTAAGTATTATTTATGAAACTTTTGCTTATATATTAAATTTTGACTGAGAAAATGAC
AATCAGGCGCTCGAAATGCAGAAAAAATTGGCAGAAAGTCCCGAATTTTTCCTAAAAAATCAAACAAATTTAGATATAAA
TGAAATTAAATTAGTGCTAAATTTTTATAAAAATCAAAAGAAAAGGCTGAAAAAATGAATTTAA

Upstream 100 bases:

>100_bases
CAGCAAAAATTATTACTTTAACTCAATTTTTAGATAAAAAATCTTATGAAAATTTAGCAAAAAAAATTAAAAAAATACAA
GAAAAAGAAGGATTTTTGTA

Downstream 100 bases:

>100_bases
AACTCGAAAATATTCATTTAAATCAAATTATTACCTCAAAAAAGCAAGCTTTTGAAAAATTAATTAGAATTTTCCAACAA
AAAAACTGTTGTGAATTTGA

Product: mannitol-1-phosphate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKVVHFGAGNIGRGLIAKLYHQNQFEIIFVDVNQNLVNDLNKNGFYYVINFENGEKYKITNFQAIHLNNKENLLKKLSSA
DIISTSIGAKNLVFLKSIFAKLAKIEEKHKQIICFENGYRVSSYFKTILEKCQFWNFVDTTIDQIAPSSNDLNVYTETFS
EIILEEKQQKIKLKTVEYLENLDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEKMKEVLQQTVLIIN
PLIEQKIMNEYFETTIKRFKNPVLQDLVVRVARNPITKISKNERFDLLLKYAKKSKISSEKLSIIYETFAYILNFDWEND
NQALEMQKKLAESPEFFLKNQTNLDINEIKLVLNFYKNQKKRLKKWI

Sequences:

>Translated_367_residues
MKVVHFGAGNIGRGLIAKLYHQNQFEIIFVDVNQNLVNDLNKNGFYYVINFENGEKYKITNFQAIHLNNKENLLKKLSSA
DIISTSIGAKNLVFLKSIFAKLAKIEEKHKQIICFENGYRVSSYFKTILEKCQF*NFVDTTIDQIAPSSNDLNVYTETFS
EIILEEKQQKIKLKTVEYLENLDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEKMKEVLQQTVLIIN
PLIEQKIMNEYFETTIKRFKNPVLQDLVVRVARNPITKISKNERFDLLLKYAKKSKISSEKLSIIYETFAYILNFD*END
NQALEMQKKLAESPEFFLKNQTNLDINEIKLVLNFYKNQKKRLKK*I
>Mature_367_residues
MKVVHFGAGNIGRGLIAKLYHQNQFEIIFVDVNQNLVNDLNKNGFYYVINFENGEKYKITNFQAIHLNNKENLLKKLSSA
DIISTSIGAKNLVFLKSIFAKLAKIEEKHKQIICFENGYRVSSYFKTILEKCQF*NFVDTTIDQIAPSSNDLNVYTETFS
EIILEEKQQKIKLKTVEYLENLDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEKMKEVLQQTVLIIN
PLIEQKIMNEYFETTIKRFKNPVLQDLVVRVARNPITKISKNERFDLLLKYAKKSKISSEKLSIIYETFAYILNFD*END
NQALEMQKKLAESPEFFLKNQTNLDINEIKLVLNFYKNQKKRLKK*I

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790028, Length=380, Percent_Identity=30.5263157894737, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR023028
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.17 [H]

Molecular weight: Translated: 42625; Mature: 42625

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVHFGAGNIGRGLIAKLYHQNQFEIIFVDVNQNLVNDLNKNGFYYVINFENGEKYKIT
CEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHCCCCCEEEEEEECCCCEEEEE
NFQAIHLNNKENLLKKLSSADIISTSIGAKNLVFLKSIFAKLAKIEEKHKQIICFENGYR
EEEEEEECCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
VSSYFKTILEKCQFNFVDTTIDQIAPSSNDLNVYTETFSEIILEEKQQKIKLKTVEYLEN
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEKMKEVLQQTVLIINP
CHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEQKIMNEYFETTIKRFKNPVLQDLVVRVARNPITKISKNERFDLLLKYAKKSKISSEK
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCHHH
LSIIYETFAYILNFDENDNQALEMQKKLAESPEFFLKNQTNLDINEIKLVLNFYKNQKKR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LKKI
HHCC
>Mature Secondary Structure
MKVVHFGAGNIGRGLIAKLYHQNQFEIIFVDVNQNLVNDLNKNGFYYVINFENGEKYKIT
CEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHCCCCCEEEEEEECCCCEEEEE
NFQAIHLNNKENLLKKLSSADIISTSIGAKNLVFLKSIFAKLAKIEEKHKQIICFENGYR
EEEEEEECCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
VSSYFKTILEKCQFNFVDTTIDQIAPSSNDLNVYTETFSEIILEEKQQKIKLKTVEYLEN
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEKMKEVLQQTVLIINP
CHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEQKIMNEYFETTIKRFKNPVLQDLVVRVARNPITKISKNERFDLLLKYAKKSKISSEK
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCHHH
LSIIYETFAYILNFDENDNQALEMQKKLAESPEFFLKNQTNLDINEIKLVLNFYKNQKKR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LKKI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]