Click here to switch to the map view.

The map label for this gene is engA

Identifier: 54020024

GI number: 54020024

Start: 92913

End: 94214

Strand: Direct

Name: engA

Synonym: mhp075

Alternate gene names: 54020024

Gene position: 92913-94214 (Clockwise)

Preceding gene: 54020023

Following gene: 54020025

Centisome position: 10.41

GC content: 29.11

Gene sequence:

>1302_bases
ATGAAAAATTTAGTTGCTCTTGTTGGAAAGTCGAACGTTGGAAAATCAACACTTTTTAACCGAATAGCAGGCAAAAAAAT
TTCAATAACTGATCCACTTCCAGGTGTTACAAGGGATCGAATTTATCAAAATGTGACCTGAAATCAACATAGTTTTTTGT
TAATTGATACAGGCGGAATTCAAATTGAGAATGAAAATTTTCAGGATTTAATCAGAATTCAGGTCCAAATTGCCCTTGAA
GAAGCCGATATTTTAGTTTGAGTTCTTGATGGTACAAAAGAAATTGATTCAGAGGATCATTTTGTCCTTAGTTTATTAAG
AAAATCCAAAAAAAAAATTATTTTAGCTGCAAACAAACTTGAAAACAACAAATCTTTTGATATAAGCCTTTTTGAGTTAG
GATTTGAGAAAGTTTTTCCAATTTCTGCCTTACACGGTCATGGAGTTGGTGATTTTTTAGATGAACTTGTAGGTAATTTT
AACAAAAAAAATTTTAAAAATGAAATTTTTTTTAAATTAACTCTAATTGGCCGCCCAAATGCAGGAAAATCTAGTCTCCT
TAACTGACTTTTAGGTGAAAATCGTTCTATTATTTCAGAAATTCCCGGTACAACAAGGGATTCAATTTCTGGTTTTTGGA
AAATAAATGGACAAACTTTGGAAATTATCGATACTGCCGGGATTAGAAAAAAATCAAAACTGGCAGAATCAGTTGATTTT
TATGCATTTTTACGAGCTTTTCGCTCGCTTGATCAGGCTGATTTAACCTTGATTTTATTAGATGCTTGTCAGGATTTTCA
TCATTTTGATCTCAGAATTGCCGGTTATGCCTTTGAGAGAAATAAGCCGATAATTTTAGTTATAAACAAGTGGGATTTAA
TTCAAAAAGATACAAGAACACAACAAGAATATCTTAGGAAAATTAAAGGTAAGTTTAAATTTCTTGATTGAGCGCCGGTT
GTTTTCATTTCAGCAAAAACAGGAGAAAAAATTCATAAACTCATTGATGTTATTTTTCAAGTTAAAAATAATCTTGAAAA
AAAAATTTCAACAAATTTACTTAATCAATTTCTAATGGAAATTCAGATGATTCAACCCCATCCAAATGTTAATGGTAAAA
AAGTTTACTTCAACTTTTTAGAACAAATTTATGGAAAAATTCCCACTTTTATATTTTTTGTAACTGATAAAAATTTAGTC
CATTTTTCTTATCAGCGTTATATTGAAAACCAAATGCGCAAGTATTTTGATTTTTTTGGCTGTCCAATTAAAATTATTTA
TAAAAATATTACAAAAAAATAA

Upstream 100 bases:

>100_bases
CAAATTTTACAAGAGATCAAATTGTATCCCAGATTTCCAAGTTAGTTTTTCGGAAAATTGGTCAGTTTTCACTTGAAATT
TAAAGGTTAATTTTTAATTA

Downstream 100 bases:

>100_bases
GAAAATAAAGTAAAATTTATAATTATCTTAGTTATGAATGGAGTCATTAAAATGAACAAAAAAGAACTAATTGAGCAAAT
TGCAATTAAAACCAATCTTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MKNLVALVGKSNVGKSTLFNRIAGKKISITDPLPGVTRDRIYQNVTWNQHSFLLIDTGGIQIENENFQDLIRIQVQIALE
EADILVWVLDGTKEIDSEDHFVLSLLRKSKKKIILAANKLENNKSFDISLFELGFEKVFPISALHGHGVGDFLDELVGNF
NKKNFKNEIFFKLTLIGRPNAGKSSLLNWLLGENRSIISEIPGTTRDSISGFWKINGQTLEIIDTAGIRKKSKLAESVDF
YAFLRAFRSLDQADLTLILLDACQDFHHFDLRIAGYAFERNKPIILVINKWDLIQKDTRTQQEYLRKIKGKFKFLDWAPV
VFISAKTGEKIHKLIDVIFQVKNNLEKKISTNLLNQFLMEIQMIQPHPNVNGKKVYFNFLEQIYGKIPTFIFFVTDKNLV
HFSYQRYIENQMRKYFDFFGCPIKIIYKNITKK

Sequences:

>Translated_433_residues
MKNLVALVGKSNVGKSTLFNRIAGKKISITDPLPGVTRDRIYQNVT*NQHSFLLIDTGGIQIENENFQDLIRIQVQIALE
EADILV*VLDGTKEIDSEDHFVLSLLRKSKKKIILAANKLENNKSFDISLFELGFEKVFPISALHGHGVGDFLDELVGNF
NKKNFKNEIFFKLTLIGRPNAGKSSLLN*LLGENRSIISEIPGTTRDSISGFWKINGQTLEIIDTAGIRKKSKLAESVDF
YAFLRAFRSLDQADLTLILLDACQDFHHFDLRIAGYAFERNKPIILVINKWDLIQKDTRTQQEYLRKIKGKFKFLD*APV
VFISAKTGEKIHKLIDVIFQVKNNLEKKISTNLLNQFLMEIQMIQPHPNVNGKKVYFNFLEQIYGKIPTFIFFVTDKNLV
HFSYQRYIENQMRKYFDFFGCPIKIIYKNITKK
>Mature_433_residues
MKNLVALVGKSNVGKSTLFNRIAGKKISITDPLPGVTRDRIYQNVT*NQHSFLLIDTGGIQIENENFQDLIRIQVQIALE
EADILV*VLDGTKEIDSEDHFVLSLLRKSKKKIILAANKLENNKSFDISLFELGFEKVFPISALHGHGVGDFLDELVGNF
NKKNFKNEIFFKLTLIGRPNAGKSSLLN*LLGENRSIISEIPGTTRDSISGFWKINGQTLEIIDTAGIRKKSKLAESVDF
YAFLRAFRSLDQADLTLILLDACQDFHHFDLRIAGYAFERNKPIILVINKWDLIQKDTRTQQEYLRKIKGKFKFLD*APV
VFISAKTGEKIHKLIDVIFQVKNNLEKKISTNLLNQFLMEIQMIQPHPNVNGKKVYFNFLEQIYGKIPTFIFFVTDKNLV
HFSYQRYIENQMRKYFDFFGCPIKIIYKNITKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=462, Percent_Identity=29.4372294372294, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI2367268, Length=204, Percent_Identity=32.843137254902, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=31.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=172, Percent_Identity=38.3720930232558, Blast_Score=97, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- InterPro:   IPR002035 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49219; Mature: 49219

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLVALVGKSNVGKSTLFNRIAGKKISITDPLPGVTRDRIYQNVTNQHSFLLIDTGGIQ
CCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCEE
IENENFQDLIRIQVQIALEEADILVVLDGTKEIDSEDHFVLSLLRKSKKKIILAANKLEN
EECCCHHHHHEEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCC
NKSFDISLFELGFEKVFPISALHGHGVGDFLDELVGNFNKKNFKNEIFFKLTLIGRPNAG
CCCCEEEHEECCHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCC
KSSLLNLLGENRSIISEIPGTTRDSISGFWKINGQTLEIIDTAGIRKKSKLAESVDFYAF
HHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
LRAFRSLDQADLTLILLDACQDFHHFDLRIAGYAFERNKPIILVINKWDLIQKDTRTQQE
HHHHHCCCCCCCCEEEEHHHCCCCCEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHH
YLRKIKGKFKFLDAPVVFISAKTGEKIHKLIDVIFQVKNNLEKKISTNLLNQFLMEIQMI
HHHHHCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
QPHPNVNGKKVYFNFLEQIYGKIPTFIFFVTDKNLVHFSYQRYIENQMRKYFDFFGCPIK
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHCCCHH
IIYKNITKK
HHHHHHCCC
>Mature Secondary Structure
MKNLVALVGKSNVGKSTLFNRIAGKKISITDPLPGVTRDRIYQNVTNQHSFLLIDTGGIQ
CCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCEE
IENENFQDLIRIQVQIALEEADILVVLDGTKEIDSEDHFVLSLLRKSKKKIILAANKLEN
EECCCHHHHHEEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCC
NKSFDISLFELGFEKVFPISALHGHGVGDFLDELVGNFNKKNFKNEIFFKLTLIGRPNAG
CCCCEEEHEECCHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCC
KSSLLNLLGENRSIISEIPGTTRDSISGFWKINGQTLEIIDTAGIRKKSKLAESVDFYAF
HHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
LRAFRSLDQADLTLILLDACQDFHHFDLRIAGYAFERNKPIILVINKWDLIQKDTRTQQE
HHHHHCCCCCCCCEEEEHHHCCCCCEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHH
YLRKIKGKFKFLDAPVVFISAKTGEKIHKLIDVIFQVKNNLEKKISTNLLNQFLMEIQMI
HHHHHCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
QPHPNVNGKKVYFNFLEQIYGKIPTFIFFVTDKNLVHFSYQRYIENQMRKYFDFFGCPIK
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHCCCHH
IIYKNITKK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]