Click here to switch to the map view.

The map label for this gene is atpA

Identifier: 54020004

GI number: 54020004

Start: 62743

End: 64266

Strand: Direct

Name: atpA

Synonym: mhp053

Alternate gene names: 54020004

Gene position: 62743-64266 (Clockwise)

Preceding gene: 54020003

Following gene: 54020005

Centisome position: 7.03

GC content: 34.25

Gene sequence:

>1524_bases
ATGAATAAAGATATAAATATAGCCGCAATAATCAAAAATGAAATAGAAAATTTTGAAGGGAAAATTCAAAATCATGACAT
TGGAAAGGTCATTATTGTTGGTGATGGTGTTGCGCTTGTATCGGGAATTGAAAAAGTAAAATTTGGCGAACTTGTTGAAT
TTGAAAATAATGTTTTAGGAATCGCGCTAAATTTAGAACAAGATTTAATTGGCGTTGTTATTATGGCTAGTGAAAATTCA
GTTTTTCAAGGATCGATAGTTAGAAGGACAAAATCGGTAATTTCAATTACAGTTGGTGATCAACTTTTAGGACGGGTTGT
AAATGCTCTAGGAATTCCAATTGATGGAAAAGCAGAACTTGATAATAGTCTGAAAAGTGCGATTTTTACAAATGCCCCGT
CAATTATGGACAGAAAAAGTGTTGATCGGGGGCTAAAAACAGGAATTTTAGCAATTGATTCACTAGTTCCAATCGGAAAA
GGTCAGCGTGAATTAATAATTGGTGATCGCCAAACTGGAAAAACAACAATCGCAATTGATGCAATTTTAAACCAAAAAGG
AAAAAATGTTTATTGTGTTTATGTAGCAATTGGCCAAAAAAACTCAAGTGTCGCACAAATTGTTTCGCTTTTAGAAAAAA
AAGGTGCCTTTGAATATACAACAGTAATTTTGGCTGGGGCAAGCGAACTCTCACCACTCCAATACCTTGCGCCATATTCT
GGGGCGGCGATCGCCGAATACTGAATGAATAAGAAAAAAGATGTGCTAATAATTTATGATGATTTATCAAAGCATGCAAT
TGCCTATCGAACTTTGTCACTACTTTTAAGAAGGCCACCCGGAAGAGAAGCATTTCCTGGGGATATTTTTTATCAGCATT
CTTACCTCCTTGAAAGATCTGCGCAACTTTCTAATGACAAAGGTGGTGGTTCAATTACAGCTTTGCCCATAATTGAAACC
CAGGCCGGGGATATTTCTGCATATATTCCAACAAATGTAATTTCTATCACCGATGGGCAAATTTTTTTACGAGATAGTTT
GTTTAATTCTGGCCAAAAACCAGCAATTGATATTGGCCTTTCAGTCTCACGGGTTGGTTCTGCTGCCCAAACTAATTTGA
TGAAATGAGCATCTTCATCCCTAAAATTAAACTTAGCCCAGTATAATGAACTTAAAGCTTTTGCCCAGTTTGGTTCTGAT
TTAGGGCCTAGTTCACAGTTAATTTTAGATCGTGGAAATAAAATTTATGAAATTTTAAAACAAGAAAACCAATATCCACT
AACTGAAAGGCAGCAAATTATGTTGCTAATTTTGATTCGCGAAAATCTAATCGATAGTTTAGAACAAAAATCAATACCAT
TATTTAAGTCAGCGTTTTTAAAATATTGTGATTCTGAGCCCAAATTTAGAGACAAAATTGAAAAAATGGATTATAATCGT
GTTCTAGAACCCAATAATCTTGCTGGAATTCTTAAAGATATTACCGATTTTATTGAAAAATTCAATTTAGGGAATGTATT
TTAG

Upstream 100 bases:

>100_bases
TTTTTGAAAATTCACTTTTTTCCGAACTTAAACTGCTAAAACAAAATCTAAAAAAACACCTAATCACCAAAAATGATCTA
TAAATTTAAAGGTTTTTATT

Downstream 100 bases:

>100_bases
TTAATTTTTCTGTAAAAATGAGTAAAAAATGCCCAAATTAAACCGACTTAGAGCCCGATTTGTCCAGATTCAAAACATTG
AAAAAATGACAAATGTAATG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLGIALNLEQDLIGVVIMASENS
VFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAELDNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGK
GQRELIIGDRQTGKTTIAIDAILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYS
GAAIAEYWMNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSAQLSNDKGGGSITALPIIET
QAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLSVSRVGSAAQTNLMKWASSSLKLNLAQYNELKAFAQFGSD
LGPSSQLILDRGNKIYEILKQENQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNR
VLEPNNLAGILKDITDFIEKFNLGNVF

Sequences:

>Translated_507_residues
MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLGIALNLEQDLIGVVIMASENS
VFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAELDNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGK
GQRELIIGDRQTGKTTIAIDAILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYS
GAAIAEY*MNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSAQLSNDKGGGSITALPIIET
QAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLSVSRVGSAAQTNLMK*ASSSLKLNLAQYNELKAFAQFGSD
LGPSSQLILDRGNKIYEILKQENQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNR
VLEPNNLAGILKDITDFIEKFNLGNVF
>Mature_507_residues
MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLGIALNLEQDLIGVVIMASENS
VFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAELDNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGK
GQRELIIGDRQTGKTTIAIDAILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYS
GAAIAEY*MNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSAQLSNDKGGGSITALPIIET
QAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLSVSRVGSAAQTNLMK*ASSSLKLNLAQYNELKAFAQFGSD
LGPSSQLILDRGNKIYEILKQENQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNR
VLEPNNLAGILKDITDFIEKFNLGNVF

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=468, Percent_Identity=52.5641025641026, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI4757810, Length=468, Percent_Identity=52.5641025641026, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI19913426, Length=348, Percent_Identity=25.5747126436782, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI19913428, Length=326, Percent_Identity=26.9938650306748, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI32189394, Length=378, Percent_Identity=24.6031746031746, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1790172, Length=498, Percent_Identity=49.3975903614458, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1788251, Length=275, Percent_Identity=28.3636363636364, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790170, Length=381, Percent_Identity=25.1968503937008, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=467, Percent_Identity=53.1049250535332, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI71988063, Length=467, Percent_Identity=53.1049250535332, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI71988074, Length=467, Percent_Identity=49.8929336188437, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17570191, Length=348, Percent_Identity=27.0114942528736, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17510931, Length=381, Percent_Identity=25.7217847769029, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144756, Length=378, Percent_Identity=24.3386243386243, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319370, Length=467, Percent_Identity=52.6766595289079, Blast_Score=486, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6319603, Length=349, Percent_Identity=27.2206303724928, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322581, Length=374, Percent_Identity=24.5989304812834, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658560, Length=483, Percent_Identity=52.5879917184265, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=26.2458471760797, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=26.2458471760797, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=26.2458471760797, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28574560, Length=383, Percent_Identity=26.1096605744125, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638766, Length=382, Percent_Identity=25.6544502617801, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55326; Mature: 55326

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLG
CCCCCEEEEEEHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEECCCEEE
IALNLEQDLIGVVIMASENSVFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAEL
EEEECCCCEEEEEEEECCCCEECCHHHHHCCCEEEEEECHHHHHHHHHHHCCCCCCHHHH
DNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGKGQRELIIGDRQTGKTTIAID
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEE
AILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYS
EECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHCCCC
GAAIAEYMNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSA
CHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHH
QLSNDKGGGSITALPIIETQAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLS
HCCCCCCCCEEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEEHHHCCCCCCEEEECCC
VSRVGSAAQTNLMKASSSLKLNLAQYNELKAFAQFGSDLGPSSQLILDRGNKIYEILKQE
HHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHCC
NQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNRVL
CCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHCCC
EPNNLAGILKDITDFIEKFNLGNVF
CCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLG
CCCCCEEEEEEHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEECCCEEE
IALNLEQDLIGVVIMASENSVFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAEL
EEEECCCCEEEEEEEECCCCEECCHHHHHCCCEEEEEECHHHHHHHHHHHCCCCCCHHHH
DNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGKGQRELIIGDRQTGKTTIAID
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEE
AILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYS
EECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHCCCC
GAAIAEYMNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSA
CHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHH
QLSNDKGGGSITALPIIETQAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLS
HCCCCCCCCEEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEEHHHCCCCCCEEEECCC
VSRVGSAAQTNLMKASSSLKLNLAQYNELKAFAQFGSDLGPSSQLILDRGNKIYEILKQE
HHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHCC
NQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNRVL
CCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHCCC
EPNNLAGILKDITDFIEKFNLGNVF
CCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA