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The map label for this gene is argS

Identifier: 54019981

GI number: 54019981

Start: 12831

End: 14435

Strand: Direct

Name: argS

Synonym: mhp012

Alternate gene names: 54019981

Gene position: 12831-14435 (Clockwise)

Preceding gene: 54019980

Following gene: 54019982

Centisome position: 1.44

GC content: 28.29

Gene sequence:

>1605_bases
ATGAAGAAAAAAATTAGCCAGGCAATAATTAAATTTTTTAAAAATGAAAATTTAATTATTGATGAAAGTAAACTAATTAT
TGAAAAGTCAAAAAATTTTGGTGATTATAGCTCTAATGTTGCGCTAATTTTTGCTAAACAGAACAAAATTGACTCCCTAA
AATTAGCACAAACGATTAAAAATCAACTACTTTCAGAAAATTTAAATTTAGAAAAAATAGAAATCGCTCCCCCCGGCTTT
ATTAATTTTTTTATTTCCAAAAATGAATATGCAAATATAGTTTCAGAAATTATTCAAAAAGGTGAAAATTTTGGCCGTTA
TTCCTTACAAAAAAAAATAAACCTTGAATTTGTTTCGGCAAACCCGACAGGTTTTTTACATCTTGGTCATCTTCGAGGCG
CAGTTATTGGTGATATTTTAGCGAATATCCTTGAATTTAGCGGAAATTTTGTTTTTCGAGAGTATTATATTAATGACTTT
GGTAGTCAAATTGATCGCTTGGTGGGCTCAGTTTTTTCCCGATATCAACAGATTTTTAAAAAATTCCCCCTTCCTGAAGA
AGCTTATCTTGGCGAGGATATAATTTGGTGCGCGCAGAAATTTTTTCAAATTTATGCAAATAAATTTGAAAATTCATCAC
TTGACGATTTAGAAGCTTATAAAATTTTCCGTGAAAAATCTATTGAGATTTTTCTTGACGAAATTAAAGCTGATTTGGCA
AATTTATCTATAAAATTCGATGTTTTTAGCTCAGAAAGTGAACTTTTTAGGACCGAGAAAGTTCAAAAAAATTTGGCAAA
TTTACCTTTTGTTTATAAAAAAGAAGAGGCAATTTGGCTTAAAACTTCCAAATTTGGTGATCAAAAAGACCGTGTTTTAG
TTAAAAAAAACGGAGAATTTACTTATTTTTCAAGTGATATTGCATACCATTTTGAAAAAATTAATAGTAATTTTAAGCCG
GATTTTTTGATAAATATTTGGGGGGCAGACCACATTGGTTATGTTGATAGAATGAAAGCGGCACTAAAAACTGTTAATTT
AAATCAAAAATTAGATATTTTACTATATCAATTAGTAAAATTATTCAAAAATGGGCAAGAATTTAAGATGTCCAAACGAA
TGGGGAAAACTTTTACGATTAAAGATTTACTCGAACTTGTTGATCAAGATGCAATCCGTTATTTTATTAGTGAAAGAAGT
TATAACTCACTTGTCGAATTTGATATCGGTCTAGCGGCTAAAATAAGCCTGCAAAATCCGTTGTTTTTAATTCAATATGC
CCATGCAAGGGCCTCGAAATTGTTGGCAAATTCGACAATAGCTCCAGAAAAAAAATTAAAATTTGAAGCTGAAAACGAGA
CTATTTTGATTTCAAAATTAAAACAATTTGAAGAAATTGTTTTAAAAATTACAAAAAATTATAAAATTAACCTCTTAAAC
AAATATTTGCTTGAATTAGCTAATCTTTTTAACTCATTTTATTCTAATTCAAAAATAATTGGTAATCAAAATCAAAATAG
TCTCTTATCCCTGACAAAAGCAGTTCAAATAGTACTAAAAAATGGACTAAAATTACTTGGGATTAAAGCCAAAGAAAGGA
TATAA

Upstream 100 bases:

>100_bases
AAAACAGGGGAAAATGATAAAATCATTGAAGTTGTTTCAGAAGGTTATAAATTACACGACCGAATTGTGAAAACAGCGCT
TGTTGTAGTTGGAAAACCTA

Downstream 100 bases:

>100_bases
AAACGTGAAAACAATCATTTCGATTGCAATTGATTTTCTAAAAAATCGTGAATCCGCTCATTTTAGCGACATTTTTTTAG
AAGTTCAAACTTCTTTGATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALIFAKQNKIDSLKLAQTIKNQLLSENLNLEKIEIAPPGF
INFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSANPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDF
GSQIDRLVGSVFSRYQQIFKKFPLPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLEAYKIFREKSIEIFLDEIKADLA
NLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEFTYFSSDIAYHFEKINSNFKP
DFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVKLFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERS
YNSLVEFDIGLAAKISLQNPLFLIQYAHARASKLLANSTIAPEKKLKFEAENETILISKLKQFEEIVLKITKNYKINLLN
KYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI

Sequences:

>Translated_534_residues
MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALIFAKQNKIDSLKLAQTIKNQLLSENLNLEKIEIAPPGF
INFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSANPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDF
GSQIDRLVGSVFSRYQQIFKKFPLPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLEAYKIFREKSIEIFLDEIKADLA
NLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEFTYFSSDIAYHFEKINSNFKP
DFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVKLFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERS
YNSLVEFDIGLAAKISLQNPLFLIQYAHARASKLLANSTIAPEKKLKFEAENETILISKLKQFEEIVLKITKNYKINLLN
KYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI
>Mature_534_residues
MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALIFAKQNKIDSLKLAQTIKNQLLSENLNLEKIEIAPPGF
INFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSANPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDF
GSQIDRLVGSVFSRYQQIFKKFPLPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLEAYKIFREKSIEIFLDEIKADLA
NLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEFTYFSSDIAYHFEKINSNFKP
DFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVKLFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERS
YNSLVEFDIGLAAKISLQNPLFLIQYAHARASKLLANSTIAPEKKLKFEAENETILISKLKQFEEIVLKITKNYKINLLN
KYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=592, Percent_Identity=25.8445945945946, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI15149476, Length=171, Percent_Identity=28.0701754385965, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1788184, Length=599, Percent_Identity=24.3739565943239, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71985061, Length=576, Percent_Identity=23.2638888888889, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=544, Percent_Identity=23.5294117647059, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=525, Percent_Identity=25.7142857142857, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321883, Length=534, Percent_Identity=23.7827715355805, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI18859963, Length=571, Percent_Identity=22.9422066549912, Blast_Score=100, Evalue=5e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MYCH2 (Q602D8)

Other databases:

- EMBL:   AE017332
- RefSeq:   YP_115527.1
- ProteinModelPortal:   Q602D8
- STRING:   Q602D8
- GeneID:   3105433
- GenomeReviews:   AE017332_GR
- KEGG:   mhy:mhp012
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   MHYO295358:MHP012-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61651; Mature: 61651

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALIFAKQNKIDSLKLAQTIK
CCHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHH
NQLLSENLNLEKIEIAPPGFINFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSA
HHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEC
NPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDFGSQIDRLVGSVFSRYQQIFK
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KFPLPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLEAYKIFREKSIEIFLDEIKADLA
HCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEF
CCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCCEEEEECCCE
TYFSSDIAYHFEKINSNFKPDFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVK
EEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERSYNSLVEFDIGLAAKISLQNP
HHCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCC
LFLIQYAHARASKLLANSTIAPEKKLKFEAENETILISKLKQFEEIVLKITKNYKINLLN
EEEEEEHHHHHHHHHHCCCCCCCHHCEEECCCCEEHHHHHHHHHHHHHHHHCCCEEEHHH
KYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI
HHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCEEEEECHHCCC
>Mature Secondary Structure
MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALIFAKQNKIDSLKLAQTIK
CCHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHH
NQLLSENLNLEKIEIAPPGFINFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSA
HHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEC
NPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDFGSQIDRLVGSVFSRYQQIFK
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KFPLPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLEAYKIFREKSIEIFLDEIKADLA
HCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEF
CCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCCEEEEECCCE
TYFSSDIAYHFEKINSNFKPDFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVK
EEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERSYNSLVEFDIGLAAKISLQNP
HHCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCC
LFLIQYAHARASKLLANSTIAPEKKLKFEAENETILISKLKQFEEIVLKITKNYKINLLN
EEEEEEHHHHHHHHHHCCCCCCCHHCEEECCCCEEHHHHHHHHHHHHHHHHCCCEEEHHH
KYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI
HHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCEEEEECHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA