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The map label for this gene is hrcA

Identifier: 54019979

GI number: 54019979

Start: 11091

End: 12098

Strand: Direct

Name: hrcA

Synonym: mhp010

Alternate gene names: 54019979

Gene position: 11091-12098 (Clockwise)

Preceding gene: 54019978

Following gene: 54019980

Centisome position: 1.24

GC content: 29.17

Gene sequence:

>1008_bases
ATGCCAAAATTAGACTCAAAAAAAGAAAAATATCTTAAACAAATAGTCGAAAATTTCATAAAAACCGGTGAATCTATCGG
TTCTCTTAACTTAAAACAAAGTTATGGTATCAAAAAATCACCTTCATATCTTCGGGCAATTATGAATCAACTTGAAAAGG
AAGGATTCTTAGAAAAATCTCATAGTTCAAGTGGCAGAATCCCGACTTTACAAGGTTTTCAATATTATGCGGAATTTTTA
TCTTTTGACGAAAATGAAAATTTAGCAAACAAATTAAAAGATTTATTCGCCCGTCGTCGCATAAATATTGAAAACACAAT
TTCTGAAGCCGTTAAATTAATTTCTGAATCGGTTGGTACTACCCTAATTGCAACAACAAATAACGAAAATGAACGATTAA
TGTCAATAAATTTAACGCAAATTTCCCAAAATGAAGGAATTATTGTTGTTGTTAGTTCCAGTGGTAATGTGGAAAATAAA
AAAATAACTTTTTCTGAACAGATTCCAAGACAAGATGTTAAAATTGCTATTAGACTTTTCCAGGAAAGATTAATAAATAC
ACCTTTGCTTGAAATTTCTTCAAAATTAGCTATTTTAAAACAGGAATTAGAGAAACAAATTAAACACAGCGATGAACTTT
TGCATCATTTTATGGAAAAAATTTTTAATTTTCAAGTCCAAAATAAGTCTAATATCTACAATAAAAATTCGCTGATTTTG
GACAAGGAGATTTCGCGGGCCAAACTTGTTGATTTACTTTATATAATTGAAAAAAAATCAATTTGAGAAATGCTTGAAGA
TCGAACAACAAAAGACGATGATACCCTAAAAATCAGTATAAAGTCCCCAGAAGTTTCATTTATTTCGAAAAAATTTGAAA
AATTTTTACCAATTAAGGAAATCAGTATGGTTGGGGCAGCTAAAAAAATTAATTATTCGGCCGCTCGAACAGGTATAAAA
CTTTTGGAAGATTTTTTATCAAACAAAAGCAAGATTAGAAAGGGATAA

Upstream 100 bases:

>100_bases
AGCACTTAATTCATAGTAAAAATTTTTTAAAAAAATAAAGCAAATTACTAGATAACAAATTTTGCTAATTTGCTTTATTT
TTTGTTATAATTTACCAAAG

Downstream 100 bases:

>100_bases
AAATGGTATTTGGTGATAAAAAATTACAAGAATTTGAAAATAATTTGCAAAATTTGTCTTCTGATAATGATTTAGAAGAC
AAAAAAGTTATAAATCCTGA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKSHSSSGRIPTLQGFQYYAEFL
SFDENENLANKLKDLFARRRINIENTISEAVKLISESVGTTLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENK
KITFSEQIPRQDVKIAIRLFQERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLIL
DKEISRAKLVDLLYIIEKKSIWEMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEISMVGAAKKINYSAARTGIK
LLEDFLSNKSKIRKG

Sequences:

>Translated_335_residues
MPKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKSHSSSGRIPTLQGFQYYAEFL
SFDENENLANKLKDLFARRRINIENTISEAVKLISESVGTTLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENK
KITFSEQIPRQDVKIAIRLFQERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLIL
DKEISRAKLVDLLYIIEKKSI*EMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEISMVGAAKKINYSAARTGIK
LLEDFLSNKSKIRKG
>Mature_334_residues
PKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKSHSSSGRIPTLQGFQYYAEFLS
FDENENLANKLKDLFARRRINIENTISEAVKLISESVGTTLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENKK
ITFSEQIPRQDVKIAIRLFQERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLILD
KEISRAKLVDLLYIIEKKSI*EMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEISMVGAAKKINYSAARTGIKL
LEDFLSNKSKIRKG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38252; Mature: 38121

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKS
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHCC
HSSSGRIPTLQGFQYYAEFLSFDENENLANKLKDLFARRRINIENTISEAVKLISESVGT
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
TLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENKKITFSEQIPRQDVKIAIRLF
EEEEEECCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCEEEEHHHCCHHHHHHHHHHH
QERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLIL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCEEE
DKEISRAKLVDLLYIIEKKSIEMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHH
SMVGAAKKINYSAARTGIKLLEDFLSNKSKIRKG
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
PKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKS
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHCC
HSSSGRIPTLQGFQYYAEFLSFDENENLANKLKDLFARRRINIENTISEAVKLISESVGT
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
TLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENKKITFSEQIPRQDVKIAIRLF
EEEEEECCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCEEEEHHHCCHHHHHHHHHHH
QERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLIL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCEEE
DKEISRAKLVDLLYIIEKKSIEMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHH
SMVGAAKKINYSAARTGIKLLEDFLSNKSKIRKG
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA