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The map label for this gene is ttuB [H]

Identifier: 53723223

GI number: 53723223

Start: 2974827

End: 2976134

Strand: Reverse

Name: ttuB [H]

Synonym: BPSS2206

Alternate gene names: 53723223

Gene position: 2976134-2974827 (Counterclockwise)

Preceding gene: 53723225

Following gene: 53723222

Centisome position: 93.8

GC content: 66.13

Gene sequence:

>1308_bases
ATGAGAGAACAGAACGCTTCCGGAAACACGCGCTCGCGAATCTATCGAAAGGTCGACATCCGCATCCTCGGGTTTCTCGC
AGTCTGTTACATCACGGCCTATATCGATCGCATCAACATTAGTTTCGCGAAGCTCGCGATGCAGACGGACCTCGGATGGA
GCGAGGCCGTGTACGGCCTGGGCGCCGGAATCTTCTTTCTCGGCTACATGGCGTTCGAGGTGCCGAGCAATCTGTGGCTG
ACCCGTATCGGCGCGCGGCTCACGCTGAGCCGCATCATGGTGTTGTGGGGCTTGACGTCGGCCGCGATGATGTTCGCCAC
CGACGTGACGACGTTCTACGTTTTGCGTTTTCTGCTCGGCGTGTTCGAGGCGGGCTTCAGCCCCGGCATGCTGTTCTGTC
TGACCCGCTGGTATCCGCAGGCGCGCATGGCGCGCGCGATGGCGATGCTGTTGTGCGCGGGGCCGGTGGGCGCGGTGATC
GGCGGGCCGGTTTCGACGCTCATCATGACGCAGCTCGCGGGCGCCCATGGCCTGGCCGGCTGGCAGTGGCTGTTCGTGCT
CGAAGGATTGCCCGCGGTGCTGCTCGGCATCGTGCTGTTCTTCACGCTGAGCGAGCGGCCGGCCGACGCGAAGTGGCTGA
GCGAGAACGAGAAGGCGATCCTGCTGAGTGAACTCGCTGCGGCGCCGCGCGCGGCGAGCCGGCACACCGCGTTTCGCGGG
GTCCTGAAAGATCCACGAATCTATGCGATGGCGTTTTCCTATTTCGCGATCATCTGCGGTCTCTATGCGGTCAGCTTCTG
GCTGCCCACGCTCTTGCGCGGCGCGGGCGTGAAGAACCTGCTGCACGTCGGCGCGCTGAGCGCGCTGCCCTATCTCGTGG
CGATCGTCGCGATGCAGGTGATCGGCCGGCGCTCCGACCGGCGCGGCGAGCGGCGCGTGCACAGCGCGCTCGCGCTGCTG
CTGAGCGCGGCCGCGCTCACGGGCACCGTGCTCGCGGGCGACCGGTTCGTCGTCGCGATGGTCGCGCTCGTCGCGGCGAC
CGCGCTGATGTACTCGTCGTACGCGGTGTTCTGGGCGATTCCCGCCGATTACCTGAAGGGCGACGCCGCCGCGGGCGGCA
TCGCGCTCATCAATTCGATCGGCCTGTTCGGCGGCTTCGTGAGCCCGACGATCATCGGCTGGATCAAGACCGCCACGGGC
AGCCTGCAGGCCGGGCTGATGGCGATGGTCGCGCTGTTCGTCGCGGGGGCGATCGTGCTGCTCGTGAACCGCGTCGACGC
GAACAAATGGAGCGCCGTCGCATCATGA

Upstream 100 bases:

>100_bases
GTACACCAAAGTTGCTGTCACTGGGATCATACAGTATGGAGATAATGGCCACGACAAATGAGCGCAGGAGTACGCGCACG
CAGATTCCAAAACGGGCCAT

Downstream 100 bases:

>100_bases
AGATCCTGGTCGCCGGCTTTCGGCACGAGTCGAACACGTTCGCACCCAGCAAGGCGACCTACGCGAGCTTCGCGGCGGAC
GGCGGCCGCTATCCGCTGTC

Product: transport related, membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MREQNASGNTRSRIYRKVDIRILGFLAVCYITAYIDRINISFAKLAMQTDLGWSEAVYGLGAGIFFLGYMAFEVPSNLWL
TRIGARLTLSRIMVLWGLTSAAMMFATDVTTFYVLRFLLGVFEAGFSPGMLFCLTRWYPQARMARAMAMLLCAGPVGAVI
GGPVSTLIMTQLAGAHGLAGWQWLFVLEGLPAVLLGIVLFFTLSERPADAKWLSENEKAILLSELAAAPRAASRHTAFRG
VLKDPRIYAMAFSYFAIICGLYAVSFWLPTLLRGAGVKNLLHVGALSALPYLVAIVAMQVIGRRSDRRGERRVHSALALL
LSAAALTGTVLAGDRFVVAMVALVAATALMYSSYAVFWAIPADYLKGDAAAGGIALINSIGLFGGFVSPTIIGWIKTATG
SLQAGLMAMVALFVAGAIVLLVNRVDANKWSAVAS

Sequences:

>Translated_435_residues
MREQNASGNTRSRIYRKVDIRILGFLAVCYITAYIDRINISFAKLAMQTDLGWSEAVYGLGAGIFFLGYMAFEVPSNLWL
TRIGARLTLSRIMVLWGLTSAAMMFATDVTTFYVLRFLLGVFEAGFSPGMLFCLTRWYPQARMARAMAMLLCAGPVGAVI
GGPVSTLIMTQLAGAHGLAGWQWLFVLEGLPAVLLGIVLFFTLSERPADAKWLSENEKAILLSELAAAPRAASRHTAFRG
VLKDPRIYAMAFSYFAIICGLYAVSFWLPTLLRGAGVKNLLHVGALSALPYLVAIVAMQVIGRRSDRRGERRVHSALALL
LSAAALTGTVLAGDRFVVAMVALVAATALMYSSYAVFWAIPADYLKGDAAAGGIALINSIGLFGGFVSPTIIGWIKTATG
SLQAGLMAMVALFVAGAIVLLVNRVDANKWSAVAS
>Mature_435_residues
MREQNASGNTRSRIYRKVDIRILGFLAVCYITAYIDRINISFAKLAMQTDLGWSEAVYGLGAGIFFLGYMAFEVPSNLWL
TRIGARLTLSRIMVLWGLTSAAMMFATDVTTFYVLRFLLGVFEAGFSPGMLFCLTRWYPQARMARAMAMLLCAGPVGAVI
GGPVSTLIMTQLAGAHGLAGWQWLFVLEGLPAVLLGIVLFFTLSERPADAKWLSENEKAILLSELAAAPRAASRHTAFRG
VLKDPRIYAMAFSYFAIICGLYAVSFWLPTLLRGAGVKNLLHVGALSALPYLVAIVAMQVIGRRSDRRGERRVHSALALL
LSAAALTGTVLAGDRFVVAMVALVAATALMYSSYAVFWAIPADYLKGDAAAGGIALINSIGLFGGFVSPTIIGWIKTATG
SLQAGLMAMVALFVAGAIVLLVNRVDANKWSAVAS

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=398, Percent_Identity=22.8643216080402, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082071, Length=415, Percent_Identity=35.9036144578313, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI2367379, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87082320, Length=442, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25141316, Length=310, Percent_Identity=21.2903225806452, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=310, Percent_Identity=21.2903225806452, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534558, Length=341, Percent_Identity=25.2199413489736, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=306, Percent_Identity=21.2418300653595, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319876, Length=218, Percent_Identity=29.8165137614679, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322025, Length=207, Percent_Identity=27.0531400966184, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6319250, Length=255, Percent_Identity=22.3529411764706, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=294, Percent_Identity=24.1496598639456, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321502, Length=214, Percent_Identity=26.6355140186916, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=255, Percent_Identity=20.7843137254902, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=140, Percent_Identity=25, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323032, Length=218, Percent_Identity=24.7706422018349, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24583789, Length=446, Percent_Identity=24.6636771300448, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584153, Length=360, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639764, Length=290, Percent_Identity=27.2413793103448, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648416, Length=459, Percent_Identity=22.4400871459695, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356189, Length=459, Percent_Identity=22.4400871459695, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130167, Length=318, Percent_Identity=22.0125786163522, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573299, Length=418, Percent_Identity=24.4019138755981, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46746; Mature: 46746

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREQNASGNTRSRIYRKVDIRILGFLAVCYITAYIDRINISFAKLAMQTDLGWSEAVYGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHH
GAGIFFLGYMAFEVPSNLWLTRIGARLTLSRIMVLWGLTSAAMMFATDVTTFYVLRFLLG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFEAGFSPGMLFCLTRWYPQARMARAMAMLLCAGPVGAVIGGPVSTLIMTQLAGAHGLAG
HHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCCH
WQWLFVLEGLPAVLLGIVLFFTLSERPADAKWLSENEKAILLSELAAAPRAASRHTAFRG
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHCCCCCHHHHHHHHH
VLKDPRIYAMAFSYFAIICGLYAVSFWLPTLLRGAGVKNLLHVGALSALPYLVAIVAMQV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGRRSDRRGERRVHSALALLLSAAALTGTVLAGDRFVVAMVALVAATALMYSSYAVFWAI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEEEC
PADYLKGDAAAGGIALINSIGLFGGFVSPTIIGWIKTATGSLQAGLMAMVALFVAGAIVL
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVNRVDANKWSAVAS
HHHHCCCCCHHHCCC
>Mature Secondary Structure
MREQNASGNTRSRIYRKVDIRILGFLAVCYITAYIDRINISFAKLAMQTDLGWSEAVYGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHH
GAGIFFLGYMAFEVPSNLWLTRIGARLTLSRIMVLWGLTSAAMMFATDVTTFYVLRFLLG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFEAGFSPGMLFCLTRWYPQARMARAMAMLLCAGPVGAVIGGPVSTLIMTQLAGAHGLAG
HHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCCH
WQWLFVLEGLPAVLLGIVLFFTLSERPADAKWLSENEKAILLSELAAAPRAASRHTAFRG
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHCCCCCHHHHHHHHH
VLKDPRIYAMAFSYFAIICGLYAVSFWLPTLLRGAGVKNLLHVGALSALPYLVAIVAMQV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGRRSDRRGERRVHSALALLLSAAALTGTVLAGDRFVVAMVALVAATALMYSSYAVFWAI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEEEC
PADYLKGDAAAGGIALINSIGLFGGFVSPTIIGWIKTATGSLQAGLMAMVALFVAGAIVL
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVNRVDANKWSAVAS
HHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]