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The map label for this gene is aldH [H]

Identifier: 53723083

GI number: 53723083

Start: 2799869

End: 2801308

Strand: Reverse

Name: aldH [H]

Synonym: BPSS2065

Alternate gene names: 53723083

Gene position: 2801308-2799869 (Counterclockwise)

Preceding gene: 53723084

Following gene: 53723082

Centisome position: 88.29

GC content: 60.9

Gene sequence:

>1440_bases
TTGAGAAGATCCCTCGTGACTACCGACCTTGTCGAATCCACCGCCGAACAAGTAGACGCGGCTGCCTCAGCGAGTGCAAG
CGCCGCCGAATCGTGGGCGACTTCTTCCGGCGCCGCTCGCTCTCGACTCCTGCGCGGACTGGCCAAGGCGCTTGATTCGG
AACGCCAGCCTCTCGTTGACATTGCCGATCGTGAAACGCAGCTCGGTGTTACTCGGCTGAATGGGGAGCTGGATCGCACC
GTTTTCCAGTTGCGCGCCTTTGCGGCACTAGTTGAAGCGGGGGTACCTTTTGAACAGCTTGACGACCCGGCAGTTTCCGG
CGGGCCGCCGGCAGGACACCCTCGTCTAACGAGGATTCGTGTCCCCATCGGGCCTGTGGCGATGTTTGCTGCAAGCAATT
TCCCATTTGCGTTCTCCGTGCTGGGTGGAGATACCGCTTCGGCGTTGGCCGCAGGATGCCCGGTAGTCGTGAAAGCGCAC
CCTGGCCACACGGAACTCTCACGTGCGGTTTTTGAACTCGCTTGCGCAGTGCTTTCCGCGCAGCAACTGCCAGCAGGAAT
CGTCCAGATGGTCCAGGGGACGTCAGTCGATGTTGGTGTCCGGTTGGTCCGACACCCGGCGATTTGCGCGGTTGCATTCA
CTGGATCGTTCAAAGGTGGTACAGCCCTGCAAGCGCAAGCGAACGTAAGACAACGGCCAATCCCCTTCTACGGTGAACTC
GGCTCGATCAATCCCGTCGTGGTCTTGCCCACGGCACTGCAGCACCAGCCGGAGGACTTAGCTCAAAGCCTCGCTGCGTC
CATAGCACAAGGCTCAGGCCAGTTTTGCACTTGCCCCGGACTCGTCATCGTGAGGGACAACGCAGAGGGTGCGGCTTTTA
TCGCAATGCTCGCTACCTCTCTTGCAGCCGCAAAACCGCATGCGATGTTGACCCCGGAGATTCGTCGCGCTTATGACTCA
GCCATCAACTGCATAACCACCCTGAAGGACGTGCACACATTGATCCGGCTACCACGTGATCCAGAAAAGGCGCAACCAAC
GCCATTTCTGGCGGTGGTCGACACGCAGACGTTTATGCGTCGACACGAGTTGCGTGAAGAGATCTTCGGCCCCGCCTGCA
TCGTGGTCAAGGTCGCTACGCTTGATGAGACTGTAGAGGTTCTGCAAGCTATCGAGGGTAGCCTGACGGCCACCATCTGG
GGCGCGGAATCCGCCACAGCCGGTAACCTTCGATTGGCTCGGGTGGCTATGGGCATCGCAGGGCGCGTGCTGTTCAGCGG
TGTCCCCACCGGCGTGGCCATCACCGCCGCTCAGCAGCACGGTGGCCCCTGGCCCGCGTCAACGCAGGCGTTCACGACGT
CGGTCGGACACGCTGCGCTCGATCGATTCCTTCGCCCGGTGGCGCTTCAGGATGCGCCGGAATGGCTGGTACGTCTCTGA

Upstream 100 bases:

>100_bases
ATAGCACTTCAAGAATTGCCCAGATCCGGGCGCGATACATCGCGATCCGCCTTGGGGGCTGTCTCGGTACGGCAGAGGAA
AGAGCGGGCTATCACACAAA

Downstream 100 bases:

>100_bases
ACCCGATCATGCCGAGTCCACTTTTCCAACCGCCGTAGTAGATGCACGACTCATTCGTATCGTTCTCGCCTGAGCAATAG
CTTGTGCGAAGCACGTGCAT

Product: fatty aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MRRSLVTTDLVESTAEQVDAAASASASAAESWATSSGAARSRLLRGLAKALDSERQPLVDIADRETQLGVTRLNGELDRT
VFQLRAFAALVEAGVPFEQLDDPAVSGGPPAGHPRLTRIRVPIGPVAMFAASNFPFAFSVLGGDTASALAAGCPVVVKAH
PGHTELSRAVFELACAVLSAQQLPAGIVQMVQGTSVDVGVRLVRHPAICAVAFTGSFKGGTALQAQANVRQRPIPFYGEL
GSINPVVVLPTALQHQPEDLAQSLAASIAQGSGQFCTCPGLVIVRDNAEGAAFIAMLATSLAAAKPHAMLTPEIRRAYDS
AINCITTLKDVHTLIRLPRDPEKAQPTPFLAVVDTQTFMRRHELREEIFGPACIVVKVATLDETVEVLQAIEGSLTATIW
GAESATAGNLRLARVAMGIAGRVLFSGVPTGVAITAAQQHGGPWPASTQAFTTSVGHAALDRFLRPVALQDAPEWLVRL

Sequences:

>Translated_479_residues
MRRSLVTTDLVESTAEQVDAAASASASAAESWATSSGAARSRLLRGLAKALDSERQPLVDIADRETQLGVTRLNGELDRT
VFQLRAFAALVEAGVPFEQLDDPAVSGGPPAGHPRLTRIRVPIGPVAMFAASNFPFAFSVLGGDTASALAAGCPVVVKAH
PGHTELSRAVFELACAVLSAQQLPAGIVQMVQGTSVDVGVRLVRHPAICAVAFTGSFKGGTALQAQANVRQRPIPFYGEL
GSINPVVVLPTALQHQPEDLAQSLAASIAQGSGQFCTCPGLVIVRDNAEGAAFIAMLATSLAAAKPHAMLTPEIRRAYDS
AINCITTLKDVHTLIRLPRDPEKAQPTPFLAVVDTQTFMRRHELREEIFGPACIVVKVATLDETVEVLQAIEGSLTATIW
GAESATAGNLRLARVAMGIAGRVLFSGVPTGVAITAAQQHGGPWPASTQAFTTSVGHAALDRFLRPVALQDAPEWLVRL
>Mature_479_residues
MRRSLVTTDLVESTAEQVDAAASASASAAESWATSSGAARSRLLRGLAKALDSERQPLVDIADRETQLGVTRLNGELDRT
VFQLRAFAALVEAGVPFEQLDDPAVSGGPPAGHPRLTRIRVPIGPVAMFAASNFPFAFSVLGGDTASALAAGCPVVVKAH
PGHTELSRAVFELACAVLSAQQLPAGIVQMVQGTSVDVGVRLVRHPAICAVAFTGSFKGGTALQAQANVRQRPIPFYGEL
GSINPVVVLPTALQHQPEDLAQSLAASIAQGSGQFCTCPGLVIVRDNAEGAAFIAMLATSLAAAKPHAMLTPEIRRAYDS
AINCITTLKDVHTLIRLPRDPEKAQPTPFLAVVDTQTFMRRHELREEIFGPACIVVKVATLDETVEVLQAIEGSLTATIW
GAESATAGNLRLARVAMGIAGRVLFSGVPTGVAITAAQQHGGPWPASTQAFTTSVGHAALDRFLRPVALQDAPEWLVRL

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=439, Percent_Identity=24.373576309795, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI25952152, Length=432, Percent_Identity=23.8425925925926, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787250, Length=438, Percent_Identity=26.7123287671233, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081896, Length=388, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082295, Length=476, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787558, Length=403, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786504, Length=410, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789015, Length=278, Percent_Identity=26.6187050359712, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788042, Length=293, Percent_Identity=26.6211604095563, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995606, Length=281, Percent_Identity=27.4021352313167, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71995613, Length=281, Percent_Identity=27.4021352313167, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325196, Length=429, Percent_Identity=27.7389277389277, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323822, Length=403, Percent_Identity=24.317617866005, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323821, Length=404, Percent_Identity=23.5148514851485, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 50265; Mature: 50265

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSLVTTDLVESTAEQVDAAASASASAAESWATSSGAARSRLLRGLAKALDSERQPLVD
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHH
IADRETQLGVTRLNGELDRTVFQLRAFAALVEAGVPFEQLDDPAVSGGPPAGHPRLTRIR
HCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCEEEEE
VPIGPVAMFAASNFPFAFSVLGGDTASALAAGCPVVVKAHPGHTELSRAVFELACAVLSA
CCCCHHHHHHCCCCCEEEEEECCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
QQLPAGIVQMVQGTSVDVGVRLVRHPAICAVAFTGSFKGGTALQAQANVRQRPIPFYGEL
HHCCHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
GSINPVVVLPTALQHQPEDLAQSLAASIAQGSGQFCTCPGLVIVRDNAEGAAFIAMLATS
CCCCCEEEECHHHCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCHHHHHHHHHH
LAAAKPHAMLTPEIRRAYDSAINCITTLKDVHTLIRLPRDPEKAQPTPFLAVVDTQTFMR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHH
RHELREEIFGPACIVVKVATLDETVEVLQAIEGSLTATIWGAESATAGNLRLARVAMGIA
HHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEHHHHHHHHH
GRVLFSGVPTGVAITAAQQHGGPWPASTQAFTTSVGHAALDRFLRPVALQDAPEWLVRL
HHHHHCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MRRSLVTTDLVESTAEQVDAAASASASAAESWATSSGAARSRLLRGLAKALDSERQPLVD
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHH
IADRETQLGVTRLNGELDRTVFQLRAFAALVEAGVPFEQLDDPAVSGGPPAGHPRLTRIR
HCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCEEEEE
VPIGPVAMFAASNFPFAFSVLGGDTASALAAGCPVVVKAHPGHTELSRAVFELACAVLSA
CCCCHHHHHHCCCCCEEEEEECCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
QQLPAGIVQMVQGTSVDVGVRLVRHPAICAVAFTGSFKGGTALQAQANVRQRPIPFYGEL
HHCCHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
GSINPVVVLPTALQHQPEDLAQSLAASIAQGSGQFCTCPGLVIVRDNAEGAAFIAMLATS
CCCCCEEEECHHHCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCHHHHHHHHHH
LAAAKPHAMLTPEIRRAYDSAINCITTLKDVHTLIRLPRDPEKAQPTPFLAVVDTQTFMR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHH
RHELREEIFGPACIVVKVATLDETVEVLQAIEGSLTATIWGAESATAGNLRLARVAMGIA
HHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEHHHHHHHHH
GRVLFSGVPTGVAITAAQQHGGPWPASTQAFTTSVGHAALDRFLRPVALQDAPEWLVRL
HHHHHCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]