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The map label for this gene is dctA [H]

Identifier: 53723075

GI number: 53723075

Start: 2792731

End: 2793330

Strand: Reverse

Name: dctA [H]

Synonym: BPSS2058

Alternate gene names: 53723075

Gene position: 2793330-2792731 (Counterclockwise)

Preceding gene: 53723076

Following gene: 53723074

Centisome position: 88.03

GC content: 57.83

Gene sequence:

>600_bases
ATGACGAAAAAGTGGAAGCTTACCCATTGGATCATGCTCGGCATGATCCTCGGTATCGTCGTAGGCTACGCCTGCCATCA
ATATGCGGCAGACGAAGCTACCGCGAAGGCCATTGCCGCCGACTTCGGCGTGGTGACGACGATTTTCTTGCACATGGTCA
AGATGATTATCGCGCCGCTGGTCTTCGCGACACTCGTCTCCGGCATTGCCAGCATGGACAGCGGGAAATCGATCGGGCGG
ATCGGCGCGAAGGTGCTCGGCTGGTTCATTGTCGCGTCCCTCGTGTCGCTCAGCATCGGCCTGCTGTTCGTCAACATCGC
GAAACCCGGTGCCAATCTCAACATGCCGCTGCCGCCAGCGAATGCTTCGACCCATCTGCAAGCGAGCGCGCTTAGCGTAA
AAGAGTTCTATCGATGTATTGGGGTCGTACCTGTTTGGAGGGCGCAGCATCTGGGTCTCCACTCTCAAGCTCTGATTTTC
GGCGAATGCCGCGGTTGGCTCGAGTGCCGACGTCGCGACTCGTGTGTTCGCAATGCGCGTGTGACCAATGCTGCCACCTT
TGCACGTGCAAAGTTTAAGCTGATGATCGGCCCGGCGTGA

Upstream 100 bases:

>100_bases
TGTAGCGGAGTCCGCATCCTTGCATTACGGCTCAGCCGTCGAAGTGGAAGCCATCGCTTTGGCCTCCGCCATTTGATGTA
CAAGACATAGAAGGGACGCC

Downstream 100 bases:

>100_bases
GACTTCGCGAACTCGGGGTGTTCGTCCTTTTGATGCGAATTCTGGCGCTTCAGCCCGCAGCGTCACCTAGACCTAACCGC
GCCCGATGGTCAGACAGCAG

Product: ATP-binding inner membrane transport protein

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTKKWKLTHWIMLGMILGIVVGYACHQYAADEATAKAIAADFGVVTTIFLHMVKMIIAPLVFATLVSGIASMDSGKSIGR
IGAKVLGWFIVASLVSLSIGLLFVNIAKPGANLNMPLPPANASTHLQASALSVKEFYRCIGVVPVWRAQHLGLHSQALIF
GECRGWLECRRRDSCVRNARVTNAATFARAKFKLMIGPA

Sequences:

>Translated_199_residues
MTKKWKLTHWIMLGMILGIVVGYACHQYAADEATAKAIAADFGVVTTIFLHMVKMIIAPLVFATLVSGIASMDSGKSIGR
IGAKVLGWFIVASLVSLSIGLLFVNIAKPGANLNMPLPPANASTHLQASALSVKEFYRCIGVVPVWRAQHLGLHSQALIF
GECRGWLECRRRDSCVRNARVTNAATFARAKFKLMIGPA
>Mature_198_residues
TKKWKLTHWIMLGMILGIVVGYACHQYAADEATAKAIAADFGVVTTIFLHMVKMIIAPLVFATLVSGIASMDSGKSIGRI
GAKVLGWFIVASLVSLSIGLLFVNIAKPGANLNMPLPPANASTHLQASALSVKEFYRCIGVVPVWRAQHLGLHSQALIFG
ECRGWLECRRRDSCVRNARVTNAATFARAKFKLMIGPA

Specific function: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1790514, Length=118, Percent_Identity=37.2881355932203, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789947, Length=85, Percent_Identity=45.8823529411765, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 21523; Mature: 21392

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKWKLTHWIMLGMILGIVVGYACHQYAADEATAKAIAADFGVVTTIFLHMVKMIIAPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFATLVSGIASMDSGKSIGRIGAKVLGWFIVASLVSLSIGLLFVNIAKPGANLNMPLPPA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
NASTHLQASALSVKEFYRCIGVVPVWRAQHLGLHSQALIFGECRGWLECRRRDSCVRNAR
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VTNAATFARAKFKLMIGPA
HHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
TKKWKLTHWIMLGMILGIVVGYACHQYAADEATAKAIAADFGVVTTIFLHMVKMIIAPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFATLVSGIASMDSGKSIGRIGAKVLGWFIVASLVSLSIGLLFVNIAKPGANLNMPLPPA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
NASTHLQASALSVKEFYRCIGVVPVWRAQHLGLHSQALIFGECRGWLECRRRDSCVRNAR
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VTNAATFARAKFKLMIGPA
HHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA