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The map label for this gene is tcp [H]

Identifier: 53722962

GI number: 53722962

Start: 2627825

End: 2629390

Strand: Reverse

Name: tcp [H]

Synonym: BPSS1941

Alternate gene names: 53722962

Gene position: 2629390-2627825 (Counterclockwise)

Preceding gene: 53722964

Following gene: 53722956

Centisome position: 82.87

GC content: 68.39

Gene sequence:

>1566_bases
ATGCCCACGCTCAGCTTCAGACAAAAGCTCTGGCTGCCGCTTGTTATCAGCCTGATCGCCCTCCTGCTCGTCTCGATCAG
CTCCGCCTGGCTTTCCTACCAGACGCGGATGGAAGAGCGCCGCAACGATCTGACGAACGTCGCGCACGTCGGCCTGAGCA
TCGTGCGGGAGTATGCGGCGCTCGCGCAGCGCGGCGTGCTCACCGATGCGCAGGCGCGCAAGGAAGCGCTCGAGCGGCTG
CGCAGCGTGCGCTACGGCAGCGACGGCTATTTCATCGTGATCGATTCGTCGCCCCGCATGATCATGCACCCGATCAAGCC
GGATACGGTCGGCAAGGACTTGCGACACGTCGCCGACGCCGACGGCCGCCATCACTACCTGACGTTCGCGTCCGTCGCGC
AATCCCCGCAAGGCGGCTTCGTCGACTATGTCTTTGCGCATCCGAACGCGCATCCCGCGAAAGCCGTCGACAAGCTCGGC
TATGTGATCCGCTACGCGCCGTGGGACTGGATCATCTCGACAGGCGCATACATCGACGACATCCAGGCGGCGTTCGCGAA
GTCGCTCTGCCTGTCCGCCGGCGTGTTCGCGTTGCTCGCCGCGCTGCTCGCGCTGAGTGTCGTCTACACGAATCGCGGCA
TCGAGCGCATGATCGGCGGCGATCCGCGCATCGCCGCGCACATGGCGGGCGTCATCGCGTCGGGCGATCTCGCGACGCCG
TTCGCCACGCGCCGGGAGGACCGCAGCAGCCTGATGTTCGCGATCAGCCAGATGCGCGACGCGCTCGCGAACGCCGTCGC
CCAGATCCGGGCAAGCGCCGGATATGTCGCGACCACGGCGGGCGAAATCGCGGACAGCAACATGGATCTGTCCTCGCACA
CCGAGTGCCAGGCGACGGCGCTGCAACAGGCGGCGTCGAGCATGCAGCGGCTCACGGAGAGGGTGCGCGACACGGCGGAC
CGCGCACGCGCCGCGAGCGAGCTGGCGGGCAGCGCCGCGCGGATCACGGATCGCGGCGGCGACATGGTCGTGCGGGTCGT
CGCGGCGATGAACGACATCCGCGCCGAGTCGCGGAAGATGGTCGACATCATCGGTGTCATCGAGGGCATCGCGTTCCAGA
CCAACATCCTCGCGCTGAACGCCGCGGTCGAAGCGGCGCGCGCGGGCAACGAAGGGCGGGGCTTCGCGGTCGTCGCGAGC
GAGGTGCGCGTGCTCGCGCAGCGCAGCGCGAGCGCGGCGAAGGACATTCGCGCGCTGATCGGCCGTGCGGCCGAGCGCGT
CGGCAACGGGGCGGAACTCGTCGAGGCGACGGGTGCGACGATCGGCGAAGCGCAGCACGCGATCTGCCGCGTGACCGGCA
TCGTGCAGGATATCGCGGCGGCCGCGACGGATCAGAGCCAGGGGCTCGAGCAGATCAACGCCGCCGTCTCGCAAATGGAC
AGCGTGACGCGGCGCAACGCGACGCTGGTCGAGCACGCCGCCATCGCCGCGCAATCGCTCAACGAGCAATCCCGGTGTCT
TCAGGACGCGGTGGCCGCATTCAGGACGGAAGCGCTCGGCTGCTGA

Upstream 100 bases:

>100_bases
TCGGGTTTAACAGTACGCATCCGCGTATTCTTCCGCCGTTAACGCGGGAGCACAGCCCGAAATCGCGCCATTTCATCGCC
GTACTACCAGGAATGCCCGG

Downstream 100 bases:

>100_bases
CGGCTGCGCGGCCGTCAGCCCGCGCAGCGCATGGGCGCTACGCGCCGCGGCGCGCGGTGTTCGATCGCGGCGAGCGCCGC
CAAGCGGCCGTCTATTCGTT

Product: methyl-accepting chemotaxis transducer transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERL
RSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLG
YVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATP
FATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTAD
RARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVAS
EVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMD
SVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC

Sequences:

>Translated_521_residues
MPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERL
RSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLG
YVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATP
FATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTAD
RARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVAS
EVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMD
SVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>Mature_520_residues
PTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLR
SVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGY
VIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPF
ATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADR
ARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASE
VRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDS
VTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=49.1803278688525, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1788194, Length=352, Percent_Identity=43.1818181818182, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI2367378, Length=349, Percent_Identity=44.4126074498567, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=45.3703703703704, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1789453, Length=334, Percent_Identity=33.2335329341317, Blast_Score=158, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55668; Mature: 55537

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADA
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHCC
DGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDD
CCCEEEEEHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCEEEECCHHHHHCCCCHHHH
IQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCCCCCC
FATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCCCCHHHHHH
LQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
GRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMD
HHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
HHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADA
HHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHCC
DGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDD
CCCEEEEEHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCEEEECCHHHHHCCCCHHHH
IQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCCCCCC
FATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCCCCHHHHHH
LQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
GRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMD
HHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
HHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]