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The map label for this gene is epsB [H]

Identifier: 53722849

GI number: 53722849

Start: 2488808

End: 2491027

Strand: Reverse

Name: epsB [H]

Synonym: BPSS1830

Alternate gene names: 53722849

Gene position: 2491027-2488808 (Counterclockwise)

Preceding gene: 53722850

Following gene: 53722848

Centisome position: 78.51

GC content: 67.75

Gene sequence:

>2220_bases
ATGGTGAATACGCAAGCGAAACATCCTTATGCCGACCTCGCGGTGAAGACCGACGAGGAAGACGTCGTCCTGGGCCAGAT
GATCCAGGTGATTCTCGACGATATCTGGCTGCTCCTCGGCATCGCGTTGGTCGTGGTCGCGCTCGCCGGGCTCTACTGCT
ACGTCGCGAAGCCGCTCTATTCGGCCGATGCGCAGGTGCGGGTGGAGGCGAGCGACAACACGTCGCAGGCGCTTACGCAG
ACGCAGACGGGCGCGATGATCAACAGCGGGCCGCCGACGCCGCCCACCGATGCGGAAATCGAGATCATCAAGAGCCGCGG
CGTCGTCGCGCCGGTCGTCGAGCAGTTCAAGCTGAACGCGTCGGTCACGCCGAACACGTTGCCGATTCTCGGCGCGATCG
CCGCGCGGCTCGCGACGCCGGGCCATCCGGGCAAACCGTGGCTCGGCTTGTCGTCGTACGCGTGGGGCGGCGAGGAGGCG
AGCATCGATTCGATCGACGTGACGCCCGTGCTCGAAGGCAAGCAGCTCACGCTCACGGCCGGCGCGGACGGCGGCTACGC
GCTCGCCGATCCGGACGGCGCGGTGCTCGTGCGCGGCAAGGTCGGCGAGCGCGAGCAGGGCGGCGGCGTGACGATCAACG
TCTCGAAGCTCGTCGCGCGCCCCGGCACGCGCTTCACGGTGGTCCGGCAGAACGATCTCGATGCGATCACCGCGTTCCAG
TCGGCGATCCAGGTGGCCGAGCAGGGCAAGCAGACCGGCGTGATCCAGATCTCGCTCGAAGGCAAGGACCCCGAACAGAC
CGCGCAGATCGCGAACGCGCTCGCGCAGTCGTATCTGCATCAGCACGTGACGAGCAAGCAGGCCGAAGCGACGAAGATGC
TCGAGTTCCTGAAGAACGAAGAGCCGCGCCTGAAATCGGACCTCGAGCGCGCGGAGGCGGAGCTCACCCAGTATCAGCGC
ACGTCGGGCTCGATCAACGCGAGCGACGAAGCGAAGGTCTACCTCGAAGGCAGCGTCCAGTACGAGCAGCAGGTCGCCGC
GCAGCGGCTGCAGCTCGCGGCGCTCGCGCAGCGCTACACGGACGAGCATCCGCTCGTCGTCGCGGCGAAGCAGCAGCTCG
GCCAGCTCGAGGCGGAGCGCGCGAAGTACGACGGCAAGTTCCGCGGGCTGCCGGCGACCGAAGTCAAGGCTGTCGCGTTG
CAGCGCAACGCGAAGGTTGCGGAAGACATCTACGTGCTGCTGCTCAACCGTGTGCAGGAGCTGTCGGTGCAGAAGGCCGG
CACGGGCGGCAACATCCGCCTCGTCGATGCGGCGCTGCGCCCGGGCGTGCCGGTCAAGCCGAAGAAGGTGCTGATCCTGT
CGGCGGCGACGCTGCTCGGCCTGATCCTCGGCACGAGCGTCGTGTTCCTGCGCCGCAACCTGTTCCATGGCATCGAGGAT
CCGGATCGCGTCGAACGCGCGTTCAACCTGCCGCTGTACGGCCTCGTGCCGATGAGCGCGGAGCAGGCGCGATTCGATGC
CGCCGACAAGGGCAATCGCGTGCGGCCGATTCTCGCGTGCGCGCGGCCGAAGGATCTGAGCGTCGAAAGCCTGCGCAGCC
TGCGCACCGCGATGCAGTTCGCGCTGATGGATGCGAAGAACCGCGTGATCGTGCTGACCGGACCGACCCCCGGCATCGGC
AAGAGCTTTCTCGCGGTCAACCTCGCCGCGCTCGTCGCGCATTCGGGCAAGCGCGTGCTGCTGATCGACGCGGACATGCG
GCGCGGCTCGCTCGATCGCCACTTCGGCACCGGGGGAAGGCGCGGCCTGTCGGAATTGCTGAGCGATCAGGTCGCGCTCG
AAGAGGCGATTCGCGAAACGTCGGTGCCGGGGCTGTCGTTCATCCCGAGCGGCGCGCGCCCGCCGAATCCGTCGGAGCTG
CTGATGTCGCCGCGCCTGTCGCAATACCTCGACGGCCTCGCGAAGCGCTACGACATGGTGATCGTCGATTCGCCGCCGAT
CCTCGCCGTCACCGACGCGACGATCTTCGGCGAACTCGCCGGCTCGACGTTCCTCGTGCTGCGCTCCGGCATGCACACCG
AAGGCGAGATCGGCGACGCGATCAAGCGGCTGCGCACCGCGGGCGTGCAACTGCAAGGCGGGATCTTCAACGGCGTGCCG
GCGCGCACGCGCGGCTACGGCCGCGGCTATGCGGCCGTGCACGAATATCTGAGCGCATGA

Upstream 100 bases:

>100_bases
TTTTCCCGACGATCCAGTCGATTTACTACATGAAGCAGATCACGCGCTGATCGGTCCCGGGCCGCCGCGCGCGGCCCGCC
TCAACCTCAAGCGGGAATGC

Downstream 100 bases:

>100_bases
CGCGCGCTTGTTCGATCGACGAGGTGACGATGAAAATTTCCGTACTCGTGCCGACCTTCCGGCGTCCCGCGGATCTCGCC
CGCTGTCTGATCGCGCTGCA

Product: exopolysaccharide biosynthesis related tyrosine-protein kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: EPS I polysaccharide export protein epsB [H]

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MVNTQAKHPYADLAVKTDEEDVVLGQMIQVILDDIWLLLGIALVVVALAGLYCYVAKPLYSADAQVRVEASDNTSQALTQ
TQTGAMINSGPPTPPTDAEIEIIKSRGVVAPVVEQFKLNASVTPNTLPILGAIAARLATPGHPGKPWLGLSSYAWGGEEA
SIDSIDVTPVLEGKQLTLTAGADGGYALADPDGAVLVRGKVGEREQGGGVTINVSKLVARPGTRFTVVRQNDLDAITAFQ
SAIQVAEQGKQTGVIQISLEGKDPEQTAQIANALAQSYLHQHVTSKQAEATKMLEFLKNEEPRLKSDLERAEAELTQYQR
TSGSINASDEAKVYLEGSVQYEQQVAAQRLQLAALAQRYTDEHPLVVAAKQQLGQLEAERAKYDGKFRGLPATEVKAVAL
QRNAKVAEDIYVLLLNRVQELSVQKAGTGGNIRLVDAALRPGVPVKPKKVLILSAATLLGLILGTSVVFLRRNLFHGIED
PDRVERAFNLPLYGLVPMSAEQARFDAADKGNRVRPILACARPKDLSVESLRSLRTAMQFALMDAKNRVIVLTGPTPGIG
KSFLAVNLAALVAHSGKRVLLIDADMRRGSLDRHFGTGGRRGLSELLSDQVALEEAIRETSVPGLSFIPSGARPPNPSEL
LMSPRLSQYLDGLAKRYDMVIVDSPPILAVTDATIFGELAGSTFLVLRSGMHTEGEIGDAIKRLRTAGVQLQGGIFNGVP
ARTRGYGRGYAAVHEYLSA

Sequences:

>Translated_739_residues
MVNTQAKHPYADLAVKTDEEDVVLGQMIQVILDDIWLLLGIALVVVALAGLYCYVAKPLYSADAQVRVEASDNTSQALTQ
TQTGAMINSGPPTPPTDAEIEIIKSRGVVAPVVEQFKLNASVTPNTLPILGAIAARLATPGHPGKPWLGLSSYAWGGEEA
SIDSIDVTPVLEGKQLTLTAGADGGYALADPDGAVLVRGKVGEREQGGGVTINVSKLVARPGTRFTVVRQNDLDAITAFQ
SAIQVAEQGKQTGVIQISLEGKDPEQTAQIANALAQSYLHQHVTSKQAEATKMLEFLKNEEPRLKSDLERAEAELTQYQR
TSGSINASDEAKVYLEGSVQYEQQVAAQRLQLAALAQRYTDEHPLVVAAKQQLGQLEAERAKYDGKFRGLPATEVKAVAL
QRNAKVAEDIYVLLLNRVQELSVQKAGTGGNIRLVDAALRPGVPVKPKKVLILSAATLLGLILGTSVVFLRRNLFHGIED
PDRVERAFNLPLYGLVPMSAEQARFDAADKGNRVRPILACARPKDLSVESLRSLRTAMQFALMDAKNRVIVLTGPTPGIG
KSFLAVNLAALVAHSGKRVLLIDADMRRGSLDRHFGTGGRRGLSELLSDQVALEEAIRETSVPGLSFIPSGARPPNPSEL
LMSPRLSQYLDGLAKRYDMVIVDSPPILAVTDATIFGELAGSTFLVLRSGMHTEGEIGDAIKRLRTAGVQLQGGIFNGVP
ARTRGYGRGYAAVHEYLSA
>Mature_739_residues
MVNTQAKHPYADLAVKTDEEDVVLGQMIQVILDDIWLLLGIALVVVALAGLYCYVAKPLYSADAQVRVEASDNTSQALTQ
TQTGAMINSGPPTPPTDAEIEIIKSRGVVAPVVEQFKLNASVTPNTLPILGAIAARLATPGHPGKPWLGLSSYAWGGEEA
SIDSIDVTPVLEGKQLTLTAGADGGYALADPDGAVLVRGKVGEREQGGGVTINVSKLVARPGTRFTVVRQNDLDAITAFQ
SAIQVAEQGKQTGVIQISLEGKDPEQTAQIANALAQSYLHQHVTSKQAEATKMLEFLKNEEPRLKSDLERAEAELTQYQR
TSGSINASDEAKVYLEGSVQYEQQVAAQRLQLAALAQRYTDEHPLVVAAKQQLGQLEAERAKYDGKFRGLPATEVKAVAL
QRNAKVAEDIYVLLLNRVQELSVQKAGTGGNIRLVDAALRPGVPVKPKKVLILSAATLLGLILGTSVVFLRRNLFHGIED
PDRVERAFNLPLYGLVPMSAEQARFDAADKGNRVRPILACARPKDLSVESLRSLRTAMQFALMDAKNRVIVLTGPTPGIG
KSFLAVNLAALVAHSGKRVLLIDADMRRGSLDRHFGTGGRRGLSELLSDQVALEEAIRETSVPGLSFIPSGARPPNPSEL
LMSPRLSQYLDGLAKRYDMVIVDSPPILAVTDATIFGELAGSTFLVLRSGMHTEGEIGDAIKRLRTAGVQLQGGIFNGVP
ARTRGYGRGYAAVHEYLSA

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the in

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=729, Percent_Identity=35.6652949245542, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1787216, Length=726, Percent_Identity=33.0578512396694, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR005700
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 79247; Mature: 79247

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTQAKHPYADLAVKTDEEDVVLGQMIQVILDDIWLLLGIALVVVALAGLYCYVAKPLY
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
SADAQVRVEASDNTSQALTQTQTGAMINSGPPTPPTDAEIEIIKSRGVVAPVVEQFKLNA
CCCCEEEEEECCCCHHHHHHHHCCCEECCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCC
SVTPNTLPILGAIAARLATPGHPGKPWLGLSSYAWGGEEASIDSIDVTPVLEGKQLTLTA
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEE
GADGGYALADPDGAVLVRGKVGEREQGGGVTINVSKLVARPGTRFTVVRQNDLDAITAFQ
CCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEHHHHHCCCCCEEEEEECCCCHHHHHHH
SAIQVAEQGKQTGVIQISLEGKDPEQTAQIANALAQSYLHQHVTSKQAEATKMLEFLKNE
HHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPRLKSDLERAEAELTQYQRTSGSINASDEAKVYLEGSVQYEQQVAAQRLQLAALAQRYT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHC
DEHPLVVAAKQQLGQLEAERAKYDGKFRGLPATEVKAVALQRNAKVAEDIYVLLLNRVQE
CCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSVQKAGTGGNIRLVDAALRPGVPVKPKKVLILSAATLLGLILGTSVVFLRRNLFHGIED
HHHHCCCCCCCEEEEEEHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDRVERAFNLPLYGLVPMSAEQARFDAADKGNRVRPILACARPKDLSVESLRSLRTAMQF
HHHHHHHHCCCEEEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
ALMDAKNRVIVLTGPTPGIGKSFLAVNLAALVAHSGKRVLLIDADMRRGSLDRHFGTGGR
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCCHH
RGLSELLSDQVALEEAIRETSVPGLSFIPSGARPPNPSELLMSPRLSQYLDGLAKRYDMV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCEE
IVDSPPILAVTDATIFGELAGSTFLVLRSGMHTEGEIGDAIKRLRTAGVQLQGGIFNGVP
EECCCCEEEEECHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCCC
ARTRGYGRGYAAVHEYLSA
CCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVNTQAKHPYADLAVKTDEEDVVLGQMIQVILDDIWLLLGIALVVVALAGLYCYVAKPLY
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
SADAQVRVEASDNTSQALTQTQTGAMINSGPPTPPTDAEIEIIKSRGVVAPVVEQFKLNA
CCCCEEEEEECCCCHHHHHHHHCCCEECCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCC
SVTPNTLPILGAIAARLATPGHPGKPWLGLSSYAWGGEEASIDSIDVTPVLEGKQLTLTA
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEE
GADGGYALADPDGAVLVRGKVGEREQGGGVTINVSKLVARPGTRFTVVRQNDLDAITAFQ
CCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEHHHHHCCCCCEEEEEECCCCHHHHHHH
SAIQVAEQGKQTGVIQISLEGKDPEQTAQIANALAQSYLHQHVTSKQAEATKMLEFLKNE
HHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPRLKSDLERAEAELTQYQRTSGSINASDEAKVYLEGSVQYEQQVAAQRLQLAALAQRYT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHC
DEHPLVVAAKQQLGQLEAERAKYDGKFRGLPATEVKAVALQRNAKVAEDIYVLLLNRVQE
CCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSVQKAGTGGNIRLVDAALRPGVPVKPKKVLILSAATLLGLILGTSVVFLRRNLFHGIED
HHHHCCCCCCCEEEEEEHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDRVERAFNLPLYGLVPMSAEQARFDAADKGNRVRPILACARPKDLSVESLRSLRTAMQF
HHHHHHHHCCCEEEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
ALMDAKNRVIVLTGPTPGIGKSFLAVNLAALVAHSGKRVLLIDADMRRGSLDRHFGTGGR
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCCHH
RGLSELLSDQVALEEAIRETSVPGLSFIPSGARPPNPSELLMSPRLSQYLDGLAKRYDMV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCEE
IVDSPPILAVTDATIFGELAGSTFLVLRSGMHTEGEIGDAIKRLRTAGVQLQGGIFNGVP
EECCCCEEEEECHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCCC
ARTRGYGRGYAAVHEYLSA
CCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]