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The map label for this gene is grsT [H]

Identifier: 53722831

GI number: 53722831

Start: 2470644

End: 2471441

Strand: Reverse

Name: grsT [H]

Synonym: BPSS1812

Alternate gene names: 53722831

Gene position: 2471441-2470644 (Counterclockwise)

Preceding gene: 53722832

Following gene: 53722830

Centisome position: 77.89

GC content: 68.05

Gene sequence:

>798_bases
ATGGACGGCGCCGACATGAATGCATGCGAGGCCCGCTGGTTCCTGTTCGGCGCCGACGAACGGAAACCCGATGCGCGAAT
CCGGCTGTTCTGCTTTCACTACGCGGGTAGCGGCGGCTCGATCTTCCGCCACTGGGGCGAGGCGCTGCCGGACGATGTCG
AGCTCGTCGCGGTGCAGATGCCGGGCCGGGAGAACCGGCTGAACGAGCCGCTGCTGTATTCGATGGACGAGGCCGTGCCG
CCGCTCGTCGACGCGCTCGCGCCGTTGCTCGACCGCCCGTTCGCGTTCTTCGGGCACAGCACGGGCGCGCTGATCGGCTT
CGAGGTCGCGCGGGTGCTGCGCGCACGCGGCTATCCGCAGCCGCGCTTGCTGATCGCGTCCGCGCAGAACGCGCCCGACG
TGAAGCCGGAGGTGATTCGGCATCGATTGTCGGATGCGGAGTTCGTCGAAGTGCTGCGCGGTTGCAACGGTACGCCCGAC
GCGATCCTGCAGGACCCGGCACTGCTCGAGCTGCTGCTGCCGCGAATCCGCGCGGACGGCGCGGTGTTCGAGACGTATCG
GTACGAGCGGCAAGCGCCGCTCGATTGCCGGATCGTCGTCTTTCACGGCGCCGCCGACGCGCTCGTGCACGACGCGGGGC
TCGCCCGCTGGGCGGGCGAGACGCAGCACAGCTTCGCGCGGTACCGGTTTGCCGGCGATCACTTCTTCATTCACGACGAA
GAGGCGTCGGTGCTCGACCACATCAACCGCGAGCTCGAGCCGCTTTTGAGCGACGCGAGCTCCACTCTAATCGGATGA

Upstream 100 bases:

>100_bases
GCTCGACCGTTACTCGACGGTGCTGGTGGCGGGCGAGGACCGCTACGGCCATAACCGCGTGACCAAGCCGCTCGCCGCCG
TCGCGGCGCTCGCGTAAGCG

Downstream 100 bases:

>100_bases
CAGACAAATGGCGCAGTGGAATTCGGATGACGAGCTGTTCGCGCTGATGCGCGCCGAGCTCTCGACCTGTCCCGTCAGCG
ACGTGATGGAGGTGCTCGGG

Product: non-ribosomal peptide synthesis thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHWGEALPDDVELVAVQMPGRENRLNEPLLYSMDEAVP
PLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQPRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPD
AILQDPALLELLLPRIRADGAVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDE
EASVLDHINRELEPLLSDASSTLIG

Sequences:

>Translated_265_residues
MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHWGEALPDDVELVAVQMPGRENRLNEPLLYSMDEAVP
PLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQPRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPD
AILQDPALLELLLPRIRADGAVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDE
EASVLDHINRELEPLLSDASSTLIG
>Mature_265_residues
MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHWGEALPDDVELVAVQMPGRENRLNEPLLYSMDEAVP
PLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQPRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPD
AILQDPALLELLLPRIRADGAVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDE
EASVLDHINRELEPLLSDASSTLIG

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=250, Percent_Identity=30.4, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI8922871, Length=303, Percent_Identity=25.7425742574257, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 29502; Mature: 29502

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHWGEALPDDVELVAVQM
CCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEC
PGRENRLNEPLLYSMDEAVPPLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQ
CCCCCCCCCCHHHCCHHCCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHCCCCC
PRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPDAILQDPALLELLLPRIRADG
CEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCC
AVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDE
HHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHEEECCCEEEEECC
EASVLDHINRELEPLLSDASSTLIG
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHWGEALPDDVELVAVQM
CCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEC
PGRENRLNEPLLYSMDEAVPPLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQ
CCCCCCCCCCHHHCCHHCCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHCCCCC
PRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPDAILQDPALLELLLPRIRADG
CEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCC
AVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDE
HHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHEEECCCEEEEECC
EASVLDHINRELEPLLSDASSTLIG
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]