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The map label for this gene is folE2

Identifier: 53722782

GI number: 53722782

Start: 2415068

End: 2415877

Strand: Reverse

Name: folE2

Synonym: BPSS1761

Alternate gene names: 53722782

Gene position: 2415877-2415068 (Counterclockwise)

Preceding gene: 53722783

Following gene: 53722780

Centisome position: 76.14

GC content: 66.42

Gene sequence:

>810_bases
ATGAACCTGATGAATCCCGAATTCGCGATGCCCGACGTGCAGAGCACCGTCGATACCCGGCAGATGCCGATCCAGCGCGT
CGGCGTGCGCGCGGTCCGGCATCCGCTGACGGTGCGCACCGCGGAAGGCGAGACGCAGGCCACCGTCGGCACCTGGAATC
TCGACGTGCATCTGCCCGCCGATCAGAAGGGCACGCACATGTCGCGCTTCGTCGCGCTGCTCGAGGAGCGCGGCGGGCCG
CTGACCGCCGATGCGTTCCGCACGATGCTGGCGACGATGCTCGAGAAGCTCGAGGCGCGGGCGGGGCGCATCGAGGTGTC
GTTTCCGTATTTCGTGAACAAGACGGCGCCCGTGTCGGGCGTGCGCAGCCTGCTCGATTACGAGGTGACGCTGACGGGCG
ACGTGCGCGACGGGCTCACACGCGTGTTCGCGAAGGTGCTTGTGCCGGTGACGAGCCTTTGCCCGTGCTCGAAGAAGATT
TCCCAGTACGGCGCGCACAACCAGCGCTCGCACGTGACGATCGACGCGGAGCTCGCGGCCGACGTGCCGGTCGAAGATCT
GATCCGGATCGCGGAGGAAGAGGCCTCGTGCGAGCTATGGGGCCTCCTGAAGCGTCCCGACGAGAAGTTCGTCACCGAGC
GCGCGTACGAGAATCCGAAGTTCGTCGAGGATCTGGTGCGCGACGTCGCGCGGCGGCTCGATGCGGACGAGCGGATCGTC
GCCTATGTGCTCGAGGCGGAGAATTTCGAGTCGATCCACAATCACAGCGCGTACGCGCTGATCGAGCGAGACAAGCGGCG
AGGCGCGTGA

Upstream 100 bases:

>100_bases
TCCCCCGAAAGCATGGGCCTGCGGGCCCATGTTGCATTTCCGGCAGGCCATGCGGCATAGGGCGATGTCGCGCCGCATGA
CCCTACAAGGATCGAACAAG

Downstream 100 bases:

>100_bases
GCGCCGCTGTCGCGCGGCGGCGTTCGCCGTATTCGAGGAAGGGGCCGTTCGAATCGAACGGCCTTTTTCGTTTGGGCGTG
GCGGCGGTGCGTGTGGGTTC

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRFVALLEERGGP
LTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKI
SQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIV
AYVLEAENFESIHNHSAYALIERDKRRGA

Sequences:

>Translated_269_residues
MNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRFVALLEERGGP
LTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKI
SQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIV
AYVLEAENFESIHNHSAYALIERDKRRGA
>Mature_269_residues
MNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRFVALLEERGGP
LTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKI
SQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIV
AYVLEAENFESIHNHSAYALIERDKRRGA

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_BURM7 (A3MBD3)

Other databases:

- EMBL:   CP000547
- RefSeq:   YP_001077569.1
- ProteinModelPortal:   A3MBD3
- SMR:   A3MBD3
- GeneID:   4889713
- GenomeReviews:   CP000547_GR
- KEGG:   bmn:BMA10247_A0366
- TIGR:   BMA10247_A0366
- HOGENOM:   HBG626871
- ProtClustDB:   PRK13674
- BioCyc:   BMAL320389:BMA10247_A0366-MONOMER
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 30189; Mature: 30189

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPA
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEEEEECC
DQKGTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSG
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEECCCCCHHH
VRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAA
HHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEHHHCC
DVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIV
CCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHE
AYVLEAENFESIHNHSAYALIERDKRRGA
EHHHCCCCHHHHHCCCCEEEEECHHCCCC
>Mature Secondary Structure
MNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPA
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEEEEECC
DQKGTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSG
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEECCCCCHHH
VRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAA
HHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEHHHCC
DVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIV
CCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHE
AYVLEAENFESIHNHSAYALIERDKRRGA
EHHHCCCCHHHHHCCCCEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA