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The map label for this gene is yngE [H]

Identifier: 53722470

GI number: 53722470

Start: 1971780

End: 1973387

Strand: Reverse

Name: yngE [H]

Synonym: BPSS1447

Alternate gene names: 53722470

Gene position: 1973387-1971780 (Counterclockwise)

Preceding gene: 53722471

Following gene: 53722469

Centisome position: 62.19

GC content: 68.97

Gene sequence:

>1608_bases
ATGCCGATCATCGAATCCAAGCTGAACCCGCGTTCCGACGAATTCCGCGCGAACGCCGCGGCGCTCGAGGCGCTCGTTGC
CGACTTGCGCGAGAAAATCGACCGGCTCGCGCTCGGCGGCGGTCAGGCCGCGCGCGACAAGCATCTGTCGCGCGGCAAGC
TGCTGCCGCGCGATCGGATCGCGCAACTGCTCGATCCGGGCACGCCGTTCCTCGAGCTGTCGCAGCTCGCCGCGTACGGG
ATGTACAACGACGATGCGCCGGGCGCGGGCCTCATCACCGGCATCGGCCGGATCGCCGGCCGCGAGTGCGTGATCGTCTG
CAACGACGCGACGGTCAAGGGCGGCACCTACTATCCGGTCACGGTGAAGAAGCACGTGCGCGCGCAGGAGATCGCGGCCG
AGAACCGGCTGCCGTGCGTGTACCTCGTCGATTCGGGCGGCGCGAACCTGCCGAATCAGGACGACGTGTTCCCCGATCGA
GACCACTTCGGCCGGATCTTCTTCAACCAGGCGAACCTGTCGGCCGCGGGCATCGCGCAGATCGCGGTCGTGATGGGCTC
GTGCACCGCGGGCGGCGCGTACGTGCCCGCGATGAGCGACGAGTCGATCATCGTTCGTAACCAGGGGACGATCTTTCTCG
GCGGCCCGCCGCTCGTGAAGGCCGCCACCGGCGAGGAAGTGAGCGCCGAGGATCTCGGCGGCGGCGACGTGCACACGCGC
TTGTCCGGCGTTGCCGATCATCTCGCGCAAAACGATGCGCACGCGCTCGCGATCGCGCGCGCGATCGTCGGCAACCTGGG
CGCGCGCGGCGGCGCGGCGCCCGCGATGCGCGAGCCGCTGCCGCCGCGCTACGACGCGCGGAGCGTGTACGGGGTGATTC
CCGTCGACACGCGCAAGCCGTTCGACGTGCGCGAGGTGATCGCGCGCATCGTCGACGATTCGGCGTTCGACGAATTCAAG
GCGCGCTACGGCACGACGCTCGTCACGGGCTTCGCGCACATCTGGGGGCAGCCGGTCGGCATCGTCGCGAACAACGGCAT
TCTGTTCTCCGAATCGGCGACGAAGGGCGCGCACTTCATCGAGCTGTGCTGCCAGCGCAAGATCGCGCTCGTGTTCCTGC
AGAACATCACGGGCTTCATGGTCGGGCGCAAGTACGAGAACGAGGGCATCGCGCGCCACGGCGCGAAGATGGTGACGGCC
GTGTCGACCGCGAAGGTGCCGAAGTTCACGGTGATCATCGGCGGCTCGTTCGGCGCGGGCAACTACGGGATGTGCGGCCG
CGCGTTCGGCCCGCGCTTTCTGTGGATGTGGCCGAACGCGCGGATCTCGGTGATGGGCGGCGAGCAGGCGGCGTCGGTGC
TCGCGACCGTGCGCCGCGAGGGGATCGAGGCGAAGGGCGGCGAATGGTCGGCGCAGGATGAAGAGGCGTTCAAGCAGCCG
ATCCGCGACCAGTACGAGCGCCAGGGCCATCCGTATTACGCGAGCGCGCGCCTCTGGGACGACGGCGTGATCGACCCCGC
TCAGACGCGCGACGTGCTGGGCCTCGCGCTTGCCGCCGCGCGAAACGCGCCGATCGAGGACACGCGGTTCGGCGTGTTCC
GGATGTGA

Upstream 100 bases:

>100_bases
CTCTACGAGATCGGCGCCGGCACGAGCGAGATCCGCCGGATGCTGATCGGCCGCGAGCTGTTCGCGGAAACGGCCTGACC
TCGCGCGCGGAGCCCACGCG

Downstream 100 bases:

>100_bases
TGCCTGCCTAGGAGCCGACGATGCGCTACGAAACGATCGAAGTGACCGACGACGGCCGCGTCGCGACCGTCACGCTCGCG
CGCCCCGACGTGCGAAACGC

Product: biotin-dependent carboxyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MPIIESKLNPRSDEFRANAAALEALVADLREKIDRLALGGGQAARDKHLSRGKLLPRDRIAQLLDPGTPFLELSQLAAYG
MYNDDAPGAGLITGIGRIAGRECVIVCNDATVKGGTYYPVTVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDR
DHFGRIFFNQANLSAAGIAQIAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
LSGVADHLAQNDAHALAIARAIVGNLGARGGAAPAMREPLPPRYDARSVYGVIPVDTRKPFDVREVIARIVDDSAFDEFK
ARYGTTLVTGFAHIWGQPVGIVANNGILFSESATKGAHFIELCCQRKIALVFLQNITGFMVGRKYENEGIARHGAKMVTA
VSTAKVPKFTVIIGGSFGAGNYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRREGIEAKGGEWSAQDEEAFKQP
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLALAAARNAPIEDTRFGVFRM

Sequences:

>Translated_535_residues
MPIIESKLNPRSDEFRANAAALEALVADLREKIDRLALGGGQAARDKHLSRGKLLPRDRIAQLLDPGTPFLELSQLAAYG
MYNDDAPGAGLITGIGRIAGRECVIVCNDATVKGGTYYPVTVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDR
DHFGRIFFNQANLSAAGIAQIAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
LSGVADHLAQNDAHALAIARAIVGNLGARGGAAPAMREPLPPRYDARSVYGVIPVDTRKPFDVREVIARIVDDSAFDEFK
ARYGTTLVTGFAHIWGQPVGIVANNGILFSESATKGAHFIELCCQRKIALVFLQNITGFMVGRKYENEGIARHGAKMVTA
VSTAKVPKFTVIIGGSFGAGNYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRREGIEAKGGEWSAQDEEAFKQP
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLALAAARNAPIEDTRFGVFRM
>Mature_534_residues
PIIESKLNPRSDEFRANAAALEALVADLREKIDRLALGGGQAARDKHLSRGKLLPRDRIAQLLDPGTPFLELSQLAAYGM
YNDDAPGAGLITGIGRIAGRECVIVCNDATVKGGTYYPVTVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDRD
HFGRIFFNQANLSAAGIAQIAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTRL
SGVADHLAQNDAHALAIARAIVGNLGARGGAAPAMREPLPPRYDARSVYGVIPVDTRKPFDVREVIARIVDDSAFDEFKA
RYGTTLVTGFAHIWGQPVGIVANNGILFSESATKGAHFIELCCQRKIALVFLQNITGFMVGRKYENEGIARHGAKMVTAV
STAKVPKFTVIIGGSFGAGNYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRREGIEAKGGEWSAQDEEAFKQPI
RDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLALAAARNAPIEDTRFGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=522, Percent_Identity=66.0919540229885, Blast_Score=707, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=530, Percent_Identity=32.4528301886792, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI295821216, Length=548, Percent_Identity=31.3868613138686, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI310133460, Length=132, Percent_Identity=61.3636363636364, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17552936, Length=540, Percent_Identity=61.2962962962963, Blast_Score=704, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147359, Length=523, Percent_Identity=33.8432122370937, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI25147362, Length=494, Percent_Identity=34.412955465587, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24586065, Length=552, Percent_Identity=62.1376811594203, Blast_Score=707, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 57377; Mature: 57246

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIESKLNPRSDEFRANAAALEALVADLREKIDRLALGGGQAARDKHLSRGKLLPRDRI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHH
AQLLDPGTPFLELSQLAAYGMYNDDAPGAGLITGIGRIAGRECVIVCNDATVKGGTYYPV
HHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEECCCEEEEE
TVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDRDHFGRIFFNQANLSAAGIAQ
EHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH
IAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
HHHHHHCCCCCCEEECCCCCCEEEEEECCEEEECCCCEEEECCCCCCCHHHCCCCHHHHH
LSGVADHLAQNDAHALAIARAIVGNLGARGGAAPAMREPLPPRYDARSVYGVIPVDTRKP
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEEEEECCCCCC
FDVREVIARIVDDSAFDEFKARYGTTLVTGFAHIWGQPVGIVANNGILFSESATKGAHFI
CCHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCHHHH
ELCCQRKIALVFLQNITGFMVGRKYENEGIARHGAKMVTAVSTAKVPKFTVIIGGSFGAG
HHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHCCHHEEEHHHCCCCEEEEEEECCCCCC
NYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRREGIEAKGGEWSAQDEEAFKQP
CCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLALAAARNAPIEDTRFGVFRM
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECC
>Mature Secondary Structure 
PIIESKLNPRSDEFRANAAALEALVADLREKIDRLALGGGQAARDKHLSRGKLLPRDRI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHH
AQLLDPGTPFLELSQLAAYGMYNDDAPGAGLITGIGRIAGRECVIVCNDATVKGGTYYPV
HHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEECCCEEEEE
TVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDRDHFGRIFFNQANLSAAGIAQ
EHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH
IAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
HHHHHHCCCCCCEEECCCCCCEEEEEECCEEEECCCCEEEECCCCCCCHHHCCCCHHHHH
LSGVADHLAQNDAHALAIARAIVGNLGARGGAAPAMREPLPPRYDARSVYGVIPVDTRKP
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEEEEECCCCCC
FDVREVIARIVDDSAFDEFKARYGTTLVTGFAHIWGQPVGIVANNGILFSESATKGAHFI
CCHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCHHHH
ELCCQRKIALVFLQNITGFMVGRKYENEGIARHGAKMVTAVSTAKVPKFTVIIGGSFGAG
HHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHCCHHEEEHHHCCCCEEEEEEECCCCCC
NYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRREGIEAKGGEWSAQDEEAFKQP
CCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLALAAARNAPIEDTRFGVFRM
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]