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The map label for this gene is estA

Identifier: 53722335

GI number: 53722335

Start: 1795244

End: 1796458

Strand: Reverse

Name: estA

Synonym: BPSS1311

Alternate gene names: 53722335

Gene position: 1796458-1795244 (Counterclockwise)

Preceding gene: 53722339

Following gene: 53722333

Centisome position: 56.62

GC content: 74.49

Gene sequence:

>1215_bases
ATGAGGATCCACACGATGAATTCGGCGTTCGATGCCCCTGCATCCGCGGCAGCCGCGGCTTTCCCCCCGGCGGACGACGC
CGCGCTCGCCGCACGGCTCGACCGCGTGCTCGGCGCGGCGCTCGGCGAGCGGCGCATCGTCGGCGCGGTCGCGCTCGCCG
CGCGGCACGGCCGGCTCGTCTACCGGCGCGCGCACGGTCTCGCGGAGCGCGAGACGCAGCGGCCGATGCGCGAGGACACG
CTGTTTCGGCTGTCGTCGATCACGAAGCCGATCGTCACCGTCGCGGTGCTGCGCCTCGTCGCCGACGGCCGAATGGCGCT
CGACGCGCCGATCACGCGCTGGCTGCCCGATTTCGCGCCCGCGCTGCCCGGCGGCCGGGCGCCCGCGCTGAGCGTGCATC
AACTGCTGACCCACACGGCGGGCCTGAGCTACTGGCTGCTCGAAGCGCCCGGCTCGGCCTATCACACGCTCGGCGTCTCG
GACGGCATCGATCTCGTCGACTTCGATCTCGCGGAGAACCTGCGGCGCATCGCGGCCGCGCCGCTCGCGTTCGAGCCGGG
CAGCGCGTGGCGCTATTCGCTCGCGCTCGACGTGCTCGGCGCGGCGATCGAGCGCGAGACGGGGCGCGCGCTGCCGGACG
CGGTCGCGCGGCTCGTCACGACGCCGCTCGGGATGCGCGACACGGGCTTCGTCGCGGCCGACCCCGCGCGTTTCGCGGTG
GCGTACGCGAACGCCGCGCCGGAGCCCGCGCGGATCACCGACAACCTCGACGTGCCGTTGCCCGAGGGGCACGGCGTCGC
GGTGCGCTTCGCGCCGTCGCGGGTGTTCGACGCGACGGCGTTCGCGTCGGGCGGCGCGGGGATGTACGGCAGCGCCGACG
ACGTGCTGCGCGTGCTCGAGACGATCCGCACGGGCGGCGACGGTTTCCTGCCGGCCGCGCTCGTCGCCGCGATGCGCACC
GATCACACGGGGCCGGCCGCCGGCACGCGCGGGCCCGGCTGGGGCTTCGGCTATGGCGGCGCGGTGCTGTCCGATCCGGC
GCTCGCGCAGTCGCCGCAGAGCGCGGGAACCCTGCAATGGGGCGGCGTCTACGGGCATTCGTGGTTCGTCGACGCGGCGC
GCGGGCTCACCGTGCTGTTGATGACGAACACCGCGTATGAAGGGATGTCGGGGCCGTTGACGCTCGAGGTGCGCGACGCG
GTGTACGGCGTGTGA

Upstream 100 bases:

>100_bases
TCGCGCGACGCGCGCGCAGCTTGCGCGCATCGCCCTGGCCCGGCGCGGGGCAACGCCGGCGGAATCGGCGCGGGCTGTCT
AGAATCGACGTTTTGAACCC

Downstream 100 bases:

>100_bases
CGCACGGCGTCGCCCCGGCGCGTCGTGCCGGGGCGACGCAGGCCGACGCAGGCCGACGCAGGCCGACGCAGGCCGACGCA
GGCCGACGCAGGCCGACGCA

Product: esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRIHTMNSAFDAPASAAAAAFPPADDAALAARLDRVLGAALGERRIVGAVALAARHGRLVYRRAHGLAERETQRPMREDT
LFRLSSITKPIVTVAVLRLVADGRMALDAPITRWLPDFAPALPGGRAPALSVHQLLTHTAGLSYWLLEAPGSAYHTLGVS
DGIDLVDFDLAENLRRIAAAPLAFEPGSAWRYSLALDVLGAAIERETGRALPDAVARLVTTPLGMRDTGFVAADPARFAV
AYANAAPEPARITDNLDVPLPEGHGVAVRFAPSRVFDATAFASGGAGMYGSADDVLRVLETIRTGGDGFLPAALVAAMRT
DHTGPAAGTRGPGWGFGYGGAVLSDPALAQSPQSAGTLQWGGVYGHSWFVDAARGLTVLLMTNTAYEGMSGPLTLEVRDA
VYGV

Sequences:

>Translated_404_residues
MRIHTMNSAFDAPASAAAAAFPPADDAALAARLDRVLGAALGERRIVGAVALAARHGRLVYRRAHGLAERETQRPMREDT
LFRLSSITKPIVTVAVLRLVADGRMALDAPITRWLPDFAPALPGGRAPALSVHQLLTHTAGLSYWLLEAPGSAYHTLGVS
DGIDLVDFDLAENLRRIAAAPLAFEPGSAWRYSLALDVLGAAIERETGRALPDAVARLVTTPLGMRDTGFVAADPARFAV
AYANAAPEPARITDNLDVPLPEGHGVAVRFAPSRVFDATAFASGGAGMYGSADDVLRVLETIRTGGDGFLPAALVAAMRT
DHTGPAAGTRGPGWGFGYGGAVLSDPALAQSPQSAGTLQWGGVYGHSWFVDAARGLTVLLMTNTAYEGMSGPLTLEVRDA
VYGV
>Mature_404_residues
MRIHTMNSAFDAPASAAAAAFPPADDAALAARLDRVLGAALGERRIVGAVALAARHGRLVYRRAHGLAERETQRPMREDT
LFRLSSITKPIVTVAVLRLVADGRMALDAPITRWLPDFAPALPGGRAPALSVHQLLTHTAGLSYWLLEAPGSAYHTLGVS
DGIDLVDFDLAENLRRIAAAPLAFEPGSAWRYSLALDVLGAAIERETGRALPDAVARLVTTPLGMRDTGFVAADPARFAV
AYANAAPEPARITDNLDVPLPEGHGVAVRFAPSRVFDATAFASGGAGMYGSADDVLRVLETIRTGGDGFLPAALVAAMRT
DHTGPAAGTRGPGWGFGYGGAVLSDPALAQSPQSAGTLQWGGVYGHSWFVDAARGLTVLLMTNTAYEGMSGPLTLEVRDA
VYGV

Specific function: Acts on short-chain (C4-C6) fatty acid esters and triglycerides, including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activity; it hydrolyzes the ester bond of cephalos

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=366, Percent_Identity=25.1366120218579, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533026, Length=180, Percent_Identity=26.1111111111111, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 42263; Mature: 42263

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIHTMNSAFDAPASAAAAAFPPADDAALAARLDRVLGAALGERRIVGAVALAARHGRLV
CEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEE
YRRAHGLAERETQRPMREDTLFRLSSITKPIVTVAVLRLVADGRMALDAPITRWLPDFAP
EHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHH
ALPGGRAPALSVHQLLTHTAGLSYWLLEAPGSAYHTLGVSDGIDLVDFDLAENLRRIAAA
CCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCEEEHHHHHHHHHHHHC
PLAFEPGSAWRYSLALDVLGAAIERETGRALPDAVARLVTTPLGMRDTGFVAADPARFAV
CCEECCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHEEE
AYANAAPEPARITDNLDVPLPEGHGVAVRFAPSRVFDATAFASGGAGMYGSADDVLRVLE
EECCCCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
TIRTGGDGFLPAALVAAMRTDHTGPAAGTRGPGWGFGYGGAVLSDPALAQSPQSAGTLQW
HHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCEEE
GGVYGHSWFVDAARGLTVLLMTNTAYEGMSGPLTLEVRDAVYGV
CCCCCCHHHEECCCCEEEEEEECCCCCCCCCCEEEEEHHHHCCC
>Mature Secondary Structure
MRIHTMNSAFDAPASAAAAAFPPADDAALAARLDRVLGAALGERRIVGAVALAARHGRLV
CEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEE
YRRAHGLAERETQRPMREDTLFRLSSITKPIVTVAVLRLVADGRMALDAPITRWLPDFAP
EHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHH
ALPGGRAPALSVHQLLTHTAGLSYWLLEAPGSAYHTLGVSDGIDLVDFDLAENLRRIAAA
CCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCEEEHHHHHHHHHHHHC
PLAFEPGSAWRYSLALDVLGAAIERETGRALPDAVARLVTTPLGMRDTGFVAADPARFAV
CCEECCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHEEE
AYANAAPEPARITDNLDVPLPEGHGVAVRFAPSRVFDATAFASGGAGMYGSADDVLRVLE
EECCCCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
TIRTGGDGFLPAALVAAMRTDHTGPAAGTRGPGWGFGYGGAVLSDPALAQSPQSAGTLQW
HHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCEEE
GGVYGHSWFVDAARGLTVLLMTNTAYEGMSGPLTLEVRDAVYGV
CCCCCCHHHEECCCCEEEEEEECCCCCCCCCCEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11472796; 11847270 [H]