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The map label for this gene is hexR [H]

Identifier: 53722333

GI number: 53722333

Start: 1791684

End: 1792646

Strand: Reverse

Name: hexR [H]

Synonym: BPSS1309

Alternate gene names: 53722333

Gene position: 1792646-1791684 (Counterclockwise)

Preceding gene: 53722335

Following gene: 53722332

Centisome position: 56.5

GC content: 74.97

Gene sequence:

>963_bases
ATGCAACACCGCCGCCGCATGCCCAGCTCACCCGCCACGCCGCTTGCCGCCGAGCCGTCGATCGCCGCGCGCATCGCCGC
CGCGCTGCCGTCGCTCACGCCGATCCATCGGCGCATGGGCGAGTACGTGCTCGCGAATCCGTTCCGCGCGGCGACGATGC
GCATCGACGAGCTCGCGAACGCGGTGGACGCGTCGATCGCGACCGCGAACCGCTTCGCGCGCGCGCTCGGCTTCGACGGC
TACCCGGCGCTGCGCGCGGCGCTCGTGCGCGGCTTCGAGGCGACGCTCGCGCCCGTCGAGCGGCTGCGTTGCGCGCAGGA
GCGCGAGGCGGGCGCGCGCGGCGGCGAGCTGATCGACGCGAGCTTCGAGCAGGCGCTCGCGAACCTCGAGCGCACGCGCG
GGCGGCTCGATCGCGCGAACGTCGAGGCGGCCGTCGATTCGCTGCTCGCCGCACGCCGGATCTTCATCGTCGGGATGGGC
GCGAGCGCGTTTCTCGCCGGCTTGATGGAGCACGGGCTGTCCGTCTACCGCGACAACGTGCAATCGCTCGCGCTGCTCGG
CGGGCCGACCGATGCCGCGCGGCGCCTGTTCAGCGCGCGCGGCGACGATCTCGTCGTCGCGATCGCGTTTCCGCGCTACG
TGCACGACACGATCGAGCTCACGCGGCGCGCGGCCGAGCGCGGCGCGCCCGTGCTCGCGATCACCGACGGGCCCGATTCG
CCGATCGCGCCGTTCGCCGCGCGCGCGCTTTTCGTGCACGCGGAGCGCCGGCTCGCGGCGACCTCCGAGGCCGCGGTGCT
CGCGCTCGTCGAGGCGCTGATCGACGCGGTCGCGCATCGCTCGCAGCGCTCGGCGCGCGCGGCCGCCGAAGTGACCGAAT
TCATGCTGCCGTGGCTCGAGGCGCGGGGCGCGTGCGCCGCGCCGCCGCGCCCGCCGCGCCGTTCCAGGAAAACCGACCGA
TGA

Upstream 100 bases:

>100_bases
GGCGGGGTCTGCGGCGATCGGACGGGGCCCGTGCAAACCCCGATGAAAATTTATTTTTTCCATTTTGCCGATTGTGTAAA
TTTACTTTCATCGTCATTCG

Downstream 100 bases:

>100_bases
CTTCACCCGCAATCGTTGCGATTCACGGCGGCGCAGGCACGATCCTGCGCGAGGCGATGACGGCCGACGCCGAAGCGCAG
TACCGTGCGGAGCTTGCCGC

Product: transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQHRRRMPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASIATANRFARALGFDG
YPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQALANLERTRGRLDRANVEAAVDSLLAARRIFIVGMG
ASAFLAGLMEHGLSVYRDNVQSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVHDTIELTRRAAERGAPVLAITDGPDS
PIAPFAARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACAAPPRPPRRSRKTDR

Sequences:

>Translated_320_residues
MQHRRRMPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASIATANRFARALGFDG
YPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQALANLERTRGRLDRANVEAAVDSLLAARRIFIVGMG
ASAFLAGLMEHGLSVYRDNVQSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVHDTIELTRRAAERGAPVLAITDGPDS
PIAPFAARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACAAPPRPPRRSRKTDR
>Mature_320_residues
MQHRRRMPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASIATANRFARALGFDG
YPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQALANLERTRGRLDRANVEAAVDSLLAARRIFIVGMG
ASAFLAGLMEHGLSVYRDNVQSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVHDTIELTRRAAERGAPVLAITDGPDS
PIAPFAARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACAAPPRPPRRSRKTDR

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 34393; Mature: 34393

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHRRRMPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELAN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHCCCHHHHHHHHHHHHH
AVDASIATANRFARALGFDGYPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
SFEQALANLERTRGRLDRANVEAAVDSLLAARRIFIVGMGASAFLAGLMEHGLSVYRDNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
QSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVHDTIELTRRAAERGAPVLAITDGPDS
HHHHHCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
PIAPFAARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARGACAAPPRPPRRSRKTDR
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQHRRRMPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELAN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHCCCHHHHHHHHHHHHH
AVDASIATANRFARALGFDGYPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
SFEQALANLERTRGRLDRANVEAAVDSLLAARRIFIVGMGASAFLAGLMEHGLSVYRDNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
QSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVHDTIELTRRAAERGAPVLAITDGPDS
HHHHHCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
PIAPFAARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARGACAAPPRPPRRSRKTDR
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]