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The map label for this gene is tcmA [H]

Identifier: 53721251

GI number: 53721251

Start: 291447

End: 293084

Strand: Reverse

Name: tcmA [H]

Synonym: BPSS0216

Alternate gene names: 53721251

Gene position: 293084-291447 (Counterclockwise)

Preceding gene: 53721253

Following gene: 53721245

Centisome position: 9.24

GC content: 74.6

Gene sequence:

>1638_bases
ATGCACGACGCGCCCTCCCGCCCCGCTCCGATCGAGCCTCCCCGTCACGCTTGCGGCTCGCCCGCCGCGTCCGCACCGGC
CCGCGCCCGCGCGCTCGCGCCCGCCGCCGAGCCCGGCGCCGAAGCGCCGTCGCGCGCGTGGCGCGCGCTCGCGACCGCGT
CGGCCACCTGCTCGCTGATCGTGCTCGACACGAACGTCGTCGCCGTATCGCTGCCATCGATCGCCCGTACGCTCCATGCG
AGCTTCGCGGACATCGAATGGGTGGTGAGCGCGTACATGACCGCGTTCGCCGCATGCCTGCTGCCGGCGGGCGGGCTCGC
CGACCGCGCGGGCCGCAAGCGCGTGCTGCTCGCCGGGCTCGCGGTGTTCTTCGTCGCGTCGCTCGGCTGCGGGCTCGCGC
CGTCGGCCGCGCTCCTGAATGTCGCGCGCGCGGTCAAGGGCATCGGCGCCGCGATGCTGCTGACCTCGGCGCTCGCCGTG
ATCGCGAACCGCTTCTCCGAAGGCCGCGAGCGAGCGCGCGCATGGGCGATCTGGGGCATGTGCATGGGCGTCGCGACGGC
GATCGCGCCGCTCGTCGGCGGCGCGATCGCGCAATGGATCGGGTGGCGCTGGATCTTCCTGCTGAACCTGCCGGTGTGCA
TCGCGCTCGCCGCGGCCGTTCGCGCGACGATCGACGAATCGCGCGATCCGCACGCGAAACGCATCGACGCGCCGGGCAGC
GTGCTGTTCGGCGCGGCGCTCGCGCTCGGCATCTGGGCGCTGATCGACGCGCCGTCGCACGGCTGGACCGCGCCCGGCAC
GCTCGCGCGCTTCGCGGCGAGCGCGGCGCTCGGCGCGGCGTTCGTCGCCGCCGAGCGCTGGCAGCGGCGCCCGATGATCG
ATCTCGCGCTGTTTCGCACGCCGCGCTTCGTCGGCGCGCTGCTCGCGATGTTCGGCTACGCGGCGTGCGCACAGGTGATG
ATGACGTTCCTGCCGCTCTATCTGCAGATCGGCTTCGGGATGTCGGCGATCGACGCGGGGCTCGGCATGCTGCCGTTCGC
GCTCGCGATGATCGTCGGGCCGTCGCTCGGCGCGGCGCTGTCGGCGCGCGCGCCGGCCGCGACCGTGCTCGGCTGCGGGC
TCGCGCTGATCGGCATCGGCAATTTCGCGACCGCCGCGCTCGCCGGCGCGTCGCACTACGGTCTCGTCGCGCTCGGGATG
ATGATCACCGGCTGCGGCGCGGGCATCCTCAACGGCGACACCCAGAAGGCGATCATGGCGTGCGTGCCGCCCGAGCGCAC
CGGCATGGCGTCCGGGATCAGCACGACGACGCGGTTTTCCGCGATCGTGACGTCGGTCGGCGTGCTCGGCGCGGTGCTCG
CCGAGCAGACCCACGCGGCGCTCGCCGCACGCGTCGCGCATGCGCCGGCATTGCTCGGCGCGCTCGATCCGCGCTTCATG
TCGAGCCTGCTCGCGGGCGATCTCGCGCAGGCGATACGCAGCCTGCCGCCGCGCACCGGCGCGACGCTCGCGCACATCGC
GCCCGGCGGCTTCGCGAGCGGTTTTTCGCTCGCGCTGTGCGCGAGCGGCGCGTTCGCGCTCGCGGCGGCCGTGGCGGTGC
GGCTGCTCGTCGGCGCGCAGCCGGGGCGCGCCGCATGA

Upstream 100 bases:

>100_bases
ATTGCTTTTTCATGCAATAAAGATGAATTTCTGTGGCAATGACTTGCAACAGCCGCTCAGCCTAACATGCCGCTCTCCCC
TTCGCATCACGGTGTCCGGC

Downstream 100 bases:

>100_bases
GCGCGCGTCGAGCACGTGGGACGCGCCGCTAGCGGCGCGCCTGGCGATGCGCGGGCCGTGCAGGCCGTGCAGGCCGTTCG
GGCCGTTCGGGCCATGCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MHDAPSRPAPIEPPRHACGSPAASAPARARALAPAAEPGAEAPSRAWRALATASATCSLIVLDTNVVAVSLPSIARTLHA
SFADIEWVVSAYMTAFAACLLPAGGLADRAGRKRVLLAGLAVFFVASLGCGLAPSAALLNVARAVKGIGAAMLLTSALAV
IANRFSEGRERARAWAIWGMCMGVATAIAPLVGGAIAQWIGWRWIFLLNLPVCIALAAAVRATIDESRDPHAKRIDAPGS
VLFGAALALGIWALIDAPSHGWTAPGTLARFAASAALGAAFVAAERWQRRPMIDLALFRTPRFVGALLAMFGYAACAQVM
MTFLPLYLQIGFGMSAIDAGLGMLPFALAMIVGPSLGAALSARAPAATVLGCGLALIGIGNFATAALAGASHYGLVALGM
MITGCGAGILNGDTQKAIMACVPPERTGMASGISTTTRFSAIVTSVGVLGAVLAEQTHAALAARVAHAPALLGALDPRFM
SSLLAGDLAQAIRSLPPRTGATLAHIAPGGFASGFSLALCASGAFALAAAVAVRLLVGAQPGRAA

Sequences:

>Translated_545_residues
MHDAPSRPAPIEPPRHACGSPAASAPARARALAPAAEPGAEAPSRAWRALATASATCSLIVLDTNVVAVSLPSIARTLHA
SFADIEWVVSAYMTAFAACLLPAGGLADRAGRKRVLLAGLAVFFVASLGCGLAPSAALLNVARAVKGIGAAMLLTSALAV
IANRFSEGRERARAWAIWGMCMGVATAIAPLVGGAIAQWIGWRWIFLLNLPVCIALAAAVRATIDESRDPHAKRIDAPGS
VLFGAALALGIWALIDAPSHGWTAPGTLARFAASAALGAAFVAAERWQRRPMIDLALFRTPRFVGALLAMFGYAACAQVM
MTFLPLYLQIGFGMSAIDAGLGMLPFALAMIVGPSLGAALSARAPAATVLGCGLALIGIGNFATAALAGASHYGLVALGM
MITGCGAGILNGDTQKAIMACVPPERTGMASGISTTTRFSAIVTSVGVLGAVLAEQTHAALAARVAHAPALLGALDPRFM
SSLLAGDLAQAIRSLPPRTGATLAHIAPGGFASGFSLALCASGAFALAAAVAVRLLVGAQPGRAA
>Mature_545_residues
MHDAPSRPAPIEPPRHACGSPAASAPARARALAPAAEPGAEAPSRAWRALATASATCSLIVLDTNVVAVSLPSIARTLHA
SFADIEWVVSAYMTAFAACLLPAGGLADRAGRKRVLLAGLAVFFVASLGCGLAPSAALLNVARAVKGIGAAMLLTSALAV
IANRFSEGRERARAWAIWGMCMGVATAIAPLVGGAIAQWIGWRWIFLLNLPVCIALAAAVRATIDESRDPHAKRIDAPGS
VLFGAALALGIWALIDAPSHGWTAPGTLARFAASAALGAAFVAAERWQRRPMIDLALFRTPRFVGALLAMFGYAACAQVM
MTFLPLYLQIGFGMSAIDAGLGMLPFALAMIVGPSLGAALSARAPAATVLGCGLALIGIGNFATAALAGASHYGLVALGM
MITGCGAGILNGDTQKAIMACVPPERTGMASGISTTTRFSAIVTSVGVLGAVLAEQTHAALAARVAHAPALLGALDPRFM
SSLLAGDLAQAIRSLPPRTGATLAHIAPGGFASGFSLALCASGAFALAAAVAVRLLVGAQPGRAA

Specific function: Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=403, Percent_Identity=30.7692307692308, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790195, Length=327, Percent_Identity=32.1100917431193, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789042, Length=310, Percent_Identity=29.3548387096774, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788392, Length=338, Percent_Identity=28.1065088757396, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788710, Length=309, Percent_Identity=26.537216828479, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790146, Length=142, Percent_Identity=33.0985915492958, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325455, Length=197, Percent_Identity=29.9492385786802, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319770, Length=344, Percent_Identity=25, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324954, Length=196, Percent_Identity=27.0408163265306, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 55020; Mature: 55020

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDAPSRPAPIEPPRHACGSPAASAPARARALAPAAEPGAEAPSRAWRALATASATCSLI
CCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEE
VLDTNVVAVSLPSIARTLHASFADIEWVVSAYMTAFAACLLPAGGLADRAGRKRVLLAGL
EEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHH
AVFFVASLGCGLAPSAALLNVARAVKGIGAAMLLTSALAVIANRFSEGRERARAWAIWGM
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CMGVATAIAPLVGGAIAQWIGWRWIFLLNLPVCIALAAAVRATIDESRDPHAKRIDAPGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
VLFGAALALGIWALIDAPSHGWTAPGTLARFAASAALGAAFVAAERWQRRPMIDLALFRT
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
PRFVGALLAMFGYAACAQVMMTFLPLYLQIGFGMSAIDAGLGMLPFALAMIVGPSLGAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCCHHH
SARAPAATVLGCGLALIGIGNFATAALAGASHYGLVALGMMITGCGAGILNGDTQKAIMA
HCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHEEE
CVPPERTGMASGISTTTRFSAIVTSVGVLGAVLAEQTHAALAARVAHAPALLGALDPRFM
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SSLLAGDLAQAIRSLPPRTGATLAHIAPGGFASGFSLALCASGAFALAAAVAVRLLVGAQ
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
PGRAA
CCCCC
>Mature Secondary Structure
MHDAPSRPAPIEPPRHACGSPAASAPARARALAPAAEPGAEAPSRAWRALATASATCSLI
CCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEE
VLDTNVVAVSLPSIARTLHASFADIEWVVSAYMTAFAACLLPAGGLADRAGRKRVLLAGL
EEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHH
AVFFVASLGCGLAPSAALLNVARAVKGIGAAMLLTSALAVIANRFSEGRERARAWAIWGM
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CMGVATAIAPLVGGAIAQWIGWRWIFLLNLPVCIALAAAVRATIDESRDPHAKRIDAPGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
VLFGAALALGIWALIDAPSHGWTAPGTLARFAASAALGAAFVAAERWQRRPMIDLALFRT
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
PRFVGALLAMFGYAACAQVMMTFLPLYLQIGFGMSAIDAGLGMLPFALAMIVGPSLGAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCCHHH
SARAPAATVLGCGLALIGIGNFATAALAGASHYGLVALGMMITGCGAGILNGDTQKAIMA
HCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHEEE
CVPPERTGMASGISTTTRFSAIVTSVGVLGAVLAEQTHAALAARVAHAPALLGALDPRFM
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SSLLAGDLAQAIRSLPPRTGATLAHIAPGGFASGFSLALCASGAFALAAAVAVRLLVGAQ
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
PGRAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1592819 [H]