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The map label for this gene is prpR

Identifier: 53721240

GI number: 53721240

Start: 276127

End: 278211

Strand: Reverse

Name: prpR

Synonym: BPSS0205

Alternate gene names: 53721240

Gene position: 278211-276127 (Counterclockwise)

Preceding gene: 53721245

Following gene: 53721239

Centisome position: 8.77

GC content: 73.86

Gene sequence:

>2085_bases
ATGAGCACCCTACCCGAAACCGGCGTGCGGCCGCGCGTCTGGGCGGTCGGCATCAGCCGGCTGCGCGCGCTCTTTCGCGA
CATCGCCGACGAATACGAAGAACGCGCCGATCTGCGGATCGTCGCGCGCGGCTACGAGGAGGCGATCACGGCGCTCGCGA
CGGCGGGCGCCGAGCGCCCCGACGCGATCGTCGCCGCCGGCTCGAACGGCACCTATCTGAAGGCGCGCGTGCGCGTGCCC
GTCGTGCTCGTCAATCCGACCGGCTTCGACGTGATGCACGCGCTCGCGCGGGCGCGGCGCGATGCGGGCCGGATCGCGCT
CGTCAGCTACGGCGAGACGCCGCCCGAGGTGCGCAGTTTCGCGGCCGCGTACGGGCTCGACGTCGTGTTCGCGTCGTACC
AGAGCGCGCAGGAGGCGGACACGCGCGTGCTCGAGATGCGCGAGCGCGGCATCGAGACCGTCGTCGGGCCGGGGCTCGTC
ACCGATCTCGCGGCGAACGCCGGGATGGGCGCGGTGTTCGTCTATTCGCACGCGTCGGTGCGCGCCGCCGTGAACACCGC
GCTCGAGGTCGCGCACGCGACGCACGCGGAAGCGCTGCGCCGCGAGCGCCTCGACAACCTGCTGCAGCACCTGCGCGACG
GCGTGGTGGCGCTCGACCGCGAGGGCCGCATCGAGGCGATCAACGAGCGGCTCGCGCTCGCGCTCGGCGTATCGCCGTCG
GCCGCGGTGGGCCGCGCGCTGGACGATCTGACGCCCGAGCTGCGCACGCTGCGCGCGGCCGACGGCGACACGCTCGCGAC
GGTGCGCGGCGTGCGCTACGTCGTGCATCGCGGGCCGCTCGCCTCGAGCGGCGGCGCGCCCGGCAGCGTGCTGACGTTCC
AGGAATCGCGTGCGGTCGAGCGGCTCGACCGCACGCTGCGCTCGCATCAGCACGCGCAGCAGTTCACCGCGCGCTACCGG
CTCGACGACATCGTCGGCACGACGCCCGCGATCGCGTACGCGCGCGACCTCGCGCGGCGCTACGCGAAATCGGACGCGAC
CGTGCTGATCCTCGGCGAGAGCGGCACCGGCAAGGAGATGATCGCGCAGAGCCTGCACGCGCTGTCCGCGCGCCGCAAGT
ATCCGTTCGTCGCGGTCAACTGCGGCGCGTTTCCGGAATCGCTGCTCGAGAGCGAGCTGTTCGGCTACGAGGAAGGCGCG
TTCACCGGCGCGCGGCGCGGCGGCAAGGCGGGGCTGTTCGAGGCCGCGCACCGCGGCACGCTGTTTCTCGACGAGATCGG
CGAAATGCCCCCGTCGCTGCAAAGCCGGCTGCTGCGCGTGCTGCAGGAGCGCGAGGTCGTGCGCGTCGGCTCGACCGAGC
CGGTTCCGGTCGACATCCGCGTCGTCGCCGCGACGCACCGGCCGCTCTTCGCCGCCGTCGAGGCGGGCACGTTCCGCGCG
GATCTCTATTACCGGTTGAACATCCTGAACATCGGGCTGCCGCCGCTGCGCGAGCGCGCGGCCGACATTCCGGCGCTCGC
CGCGACGCTGCTCGCGCAGGCCGCGCGCCGCGAGCCGCGGCTCGCCGAGCGGCTGCGCGACGCCAACGATGCGGCGCGCG
CGCTCGACGCGGCGAACGCCGCGCTCGCCCGCTATCGATGGCCGGGCAACGTGCGCGAATTGCAGAACGTGATCGAGCGC
ATCGCCGTCGAGCTCGCCGACGCGGGCGAGCGCGGCGATGCGGCCGTGAGCGCCGACACGCTGCGCGCGATCGCGCCCGA
GGTGTTCGCGCTCGATACGCTCGGCGGGTTCGGCTCGTTCGGCTCGGCGGCGGGCGGCGGCCACGGCGACGCGAGCGGCG
GAGATATCGATGCCGATGCCGACGCGCGACGCCCGACGCTCGTGCAGCGCCGCCGGCGCGCGGAAGCCGACGAGATTCGC
GCGGCGCTCGACGCATGCGGCGGCGACCGCGACCGCGCGTGCGCGAGGCTCGGCATCAGCAAGACGACGCTGTGGCGCAA
GCTCGCGGCGAGCGAAGGGAAAGCGCGAGGCAATAAGCGCGGCGGCGGCCACGGCGGCGACAACGACGAAGGCGCGGGTG
CGTGA

Upstream 100 bases:

>100_bases
ATATTGAAATTAAAATTCCATAATTGAAATCTATGCGCGATAATGCGGTTCATCCCCTTTCTTCATCCGGGCGCGGCTCG
CGCCGCGCCCTCGGTCCAGT

Downstream 100 bases:

>100_bases
CTTCGCGCGGCAAGGTCGCGGTTCCTGATTCCCGGTTTCCGTTCGCCGACTGCCGGCACGCGAGCATTCGAGCGTCGTGC
GGGCTTCGCTTCGCGCGCGC

Product: sigma interaction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MSTLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERPDAIVAAGSNGTYLKARVRVP
VVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSFAAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLV
TDLAANAGMGAVFVYSHASVRAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVERLDRTLRSHQHAQQFTARYR
LDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEMIAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGA
FTGARRGGKAGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANAALARYRWPGNVRELQNVIER
IAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIR
AALDACGGDRDRACARLGISKTTLWRKLAASEGKARGNKRGGGHGGDNDEGAGA

Sequences:

>Translated_694_residues
MSTLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERPDAIVAAGSNGTYLKARVRVP
VVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSFAAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLV
TDLAANAGMGAVFVYSHASVRAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVERLDRTLRSHQHAQQFTARYR
LDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEMIAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGA
FTGARRGGKAGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANAALARYRWPGNVRELQNVIER
IAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIR
AALDACGGDRDRACARLGISKTTLWRKLAASEGKARGNKRGGGHGGDNDEGAGA
>Mature_693_residues
STLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERPDAIVAAGSNGTYLKARVRVPV
VLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSFAAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLVT
DLAANAGMGAVFVYSHASVRAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPSA
AVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVERLDRTLRSHQHAQQFTARYRL
DDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEMIAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGAF
TGARRGGKAGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRAD
LYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANAALARYRWPGNVRELQNVIERI
AVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSFGSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIRA
ALDACGGDRDRACARLGISKTTLWRKLAASEGKARGNKRGGGHGGDNDEGAGA

Specific function: Involved In The Transcriptional Regulation Of The Propionate Catabolism Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1786524, Length=391, Percent_Identity=43.2225063938619, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI1788550, Length=379, Percent_Identity=41.1609498680739, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1789233, Length=383, Percent_Identity=35.7702349869452, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI87082117, Length=270, Percent_Identity=48.1481481481481, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI1790437, Length=350, Percent_Identity=43.7142857142857, Blast_Score=236, Evalue=5e-63,
Organism=Escherichia coli, GI1788905, Length=362, Percent_Identity=40.8839779005525, Blast_Score=231, Evalue=2e-61,
Organism=Escherichia coli, GI1790299, Length=275, Percent_Identity=46.5454545454545, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789087, Length=281, Percent_Identity=45.5516014234875, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI87082152, Length=253, Percent_Identity=45.4545454545455, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87081872, Length=249, Percent_Identity=44.9799196787149, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787583, Length=306, Percent_Identity=36.9281045751634, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081858, Length=476, Percent_Identity=28.5714285714286, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=37.5, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74189; Mature: 74057

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
DAIVAAGSNGTYLKARVRVPVVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSF
CEEEEECCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
AAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLVTDLAANAGMGAVFVYSHASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHCCCCCEEEEEECHHH
RAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHEEEECCCCH
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVE
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHH
RLDRTLRSHQHAQQFTARYRLDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
IAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGAFTGARRGGKAGLFEAAHRGT
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC
LFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
EEHHHHCCCCHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEEECCCCEEEEECCCCEEE
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANA
EEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHH
ALARYRWPGNVRELQNVIERIAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSF
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHEECCCCCCCCC
GSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIRAALDACGGDRDRACARLGIS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCH
KTTLWRKLAASEGKARGNKRGGGHGGDNDEGAGA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STLPETGVRPRVWAVGISRLRALFRDIADEYEERADLRIVARGYEEAITALATAGAERP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
DAIVAAGSNGTYLKARVRVPVVLVNPTGFDVMHALARARRDAGRIALVSYGETPPEVRSF
CEEEEECCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
AAAYGLDVVFASYQSAQEADTRVLEMRERGIETVVGPGLVTDLAANAGMGAVFVYSHASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHCCCCCEEEEEECHHH
RAAVNTALEVAHATHAEALRRERLDNLLQHLRDGVVALDREGRIEAINERLALALGVSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHEEEECCCCH
AAVGRALDDLTPELRTLRAADGDTLATVRGVRYVVHRGPLASSGGAPGSVLTFQESRAVE
HHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHH
RLDRTLRSHQHAQQFTARYRLDDIVGTTPAIAYARDLARRYAKSDATVLILGESGTGKEM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
IAQSLHALSARRKYPFVAVNCGAFPESLLESELFGYEEGAFTGARRGGKAGLFEAAHRGT
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC
LFLDEIGEMPPSLQSRLLRVLQEREVVRVGSTEPVPVDIRVVAATHRPLFAAVEAGTFRA
EEHHHHCCCCHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEEECCCCEEEEECCCCEEE
DLYYRLNILNIGLPPLRERAADIPALAATLLAQAARREPRLAERLRDANDAARALDAANA
EEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHH
ALARYRWPGNVRELQNVIERIAVELADAGERGDAAVSADTLRAIAPEVFALDTLGGFGSF
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHEECCCCCCCCC
GSAAGGGHGDASGGDIDADADARRPTLVQRRRRAEADEIRAALDACGGDRDRACARLGIS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCH
KTTLWRKLAASEGKARGNKRGGGHGGDNDEGAGA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA