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The map label for this gene is recG [H]

Identifier: 53720475

GI number: 53720475

Start: 3429175

End: 3431421

Strand: Reverse

Name: recG [H]

Synonym: BPSL2867

Alternate gene names: 53720475

Gene position: 3431421-3429175 (Counterclockwise)

Preceding gene: 53720481

Following gene: 53720474

Centisome position: 84.22

GC content: 73.25

Gene sequence:

>2247_bases
GTGCCGGCCGCCGCCCAGGCGGCGCGTGCGCCTCGCGCGCCCCGAGCCGCGCCGCCCGACGCACTACCCGCCGACACGCC
GCCCGCCAGCGCGGCGAAGCCCGCCAAACGGGCGGCGAAGGCCGCCTCGAAAACGGTCTCGAAGGCGGCAGCGGACGCAG
CCGGCGCCCAGGCGGCACCGAAGGCCGTGAAAACCGCCGACAAACTCGCGAAGCTCGGCTTGACGCGCGACATCGACCTC
GTCCTGCATCTGCCGATGCGCTACGAGGACGAGACGACGCTCACGCCGATGCGCGAACTGTTGCCGGGCGAGACCGCGCA
GACGGAAGGCGTCGTGTTCGACAGCGAGATCGCGTACCGGCCGCGCCGTCAGTTGCTCGTGAAGCTGCGCGACGACGACG
GCGCCGAGCTCGTGCTGCGCTTCCTGAATTTCTACGGCTCGCAGGTCAAGCAGATGGCGGTCGGCCAGCGGCTGCGCGTG
CGCGGCGACGTGCGCGGCGGCTTCTTCGGGCTGGAGATCGTGCATCCGACGGTGAAGACCGTCGACGAGGACGCGCCGCT
GCCGCAAGCGCTGACGCCCGTCTATCCGAGCACGGCGGGCGTGTCGCAGGCGTATCTGCGCAAGGCGATCGACAATGCGC
TCGCGCGCACGCCGCTGCCCGAGCTGCTGCCGCCCGAGATCGCGCGCGCGTATCTGCAGCCGCTCGACGTGCCGCCGCTC
GCCGACGCGGTGCGCATGCTCCATCATCCGGGCGTCGGCGCGGACGAGGCGGCGCTCATCGACGGCACCCACCCCGCGTG
GACGCGCATCAAGTTCGACGAGCTGCTCGCGCAGCAACTGTCGCTCAAGCGCGCGCACGAGGAGCGCCGCACGCGCGCCG
CGCCCGCGATGCCGCGCCGCGCGCGCGACGACGGCGCGGCGCTGTCCGCGCGCCTGCACGCGGCGCTGCCGTTTGCGCTC
ACGGCCGCGCAGGAGCGCGTCGTCGCGGAGATCGCGCACGACCTCACGCAGCCGCACCCGATGCAGCGCCTGCTGCAGGG
CGACGTCGGCAGCGGCAAGACGGTCGTCGCGGCGCTCGCGGCCGCGCAGGCGATCGACGCCGGCTACCAGGCCGCGCTGA
TGGCGCCCACCGAAATCCTCGCCGAGCAGCACGCGCGCAAGCTGCGCGGCTGGCTCGAGCCGCTCGGCGTGTCGGTCGCG
TGGCTCGCCGGCAGCCTGAAGGCGAAGGACAAGCGCGCGGCGCTCGAGGCGGCCGCGCTCGGCACCGCGCAGCTCGTGAT
CGGCACGCACGCGATGATTCAGGACACCGTCGAATTCGCGCGGCTCGGGCTCGTGATCGTCGACGAGCAGCACCGCTTCG
GCGTCGAGCAGCGGCTCGCGCTGCGGGCGAAGGCGGCGAACGCGGCCGACGGCGCGGCGGGCTTCCAGCCGCACCAGCTG
ATGATGTCGGCGACGCCGATCCCGCGCACGCTCGCGATGACGTACTACGCGGATCTCGACGTGTCGACGATCGACGAGCT
GCCGCCCGGGCGCACGCCGATCCTCACGCGGCTCGTGTCGGACGCGCGGCGCGACGAGGTGATCGGCCGCGTGCGCGAGG
CGGCGCTCGCGGGCCGTCAGGTGTACTGGGTGTGCCCGCTCATCGAGGAAAGCGAGACGCTGCAACTGCAGACGGCTGTC
GAGACCTACGAGACGCTCGCCGCCGCGCTGCCCGAGCTGAAGGTGGGGCTCGTGCACGGCCGGCTCGCGCCTGCGGAGAA
GGCGGCCGTGATGGACGCGTTCTCGCGCAACGACGTGCAATTGCTCGTCGCGACGACGGTGATCGAAGTCGGCGTCGACG
TGCCGAACGCGTCGCTGATGGTGATCGAGCACGCGGAGCGCTTCGGGCTCGCGCAGCTGCACCAGCTGCGCGGGCGCGTC
GGGCGCGGCACGGCCGCGTCGGTGTGCGTGCTGATGTACAGCGGGCCGCTGTCGATCGCGGGCCGCGCGCGGCTGAAGAC
GATGCGCGAGACGACCGACGGCTTCGAGATCGCGCGCCGCGATCTGGAGATCCGCGGCCCCGGCGAATTCCTCGGCGCGC
GCCAGTCGGGCGCGGCGATGCTGCGCTTCGCGGACCTGGAAAACGACGGCTGGCTGATCGAGCCGGCGCGCGACGCGGCC
GCGCGGCTCATCGCCGCCCATCCGGAGGTCGTCGCGCAGCACCTCGCCCGCTGGCTCGGCGCGCGCGAGCAGTATCTGAA
GGCCTGA

Upstream 100 bases:

>100_bases
TCACGCGGCGGCCTGGGCGGAATTCGGCGCCGCGGCCGACGCCGGCGCGCGATCGGCGCCGCGCGCGACGCCGCGCGGCC
GCACCGCCGACGGCCGCGCC

Downstream 100 bases:

>100_bases
GCGCGGAGGCGCGACGGCCGCGCGGGCGGCGTTTCGCGCGCTTCGGACAGGCTTGTTTTCGGCGAAGGTTGGCGAATCGA
CCCAAACCAGTGTATAAATT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 748; Mature: 747

Protein sequence:

>748_residues
MPAAAQAARAPRAPRAAPPDALPADTPPASAAKPAKRAAKAASKTVSKAAADAAGAQAAPKAVKTADKLAKLGLTRDIDL
VLHLPMRYEDETTLTPMRELLPGETAQTEGVVFDSEIAYRPRRQLLVKLRDDDGAELVLRFLNFYGSQVKQMAVGQRLRV
RGDVRGGFFGLEIVHPTVKTVDEDAPLPQALTPVYPSTAGVSQAYLRKAIDNALARTPLPELLPPEIARAYLQPLDVPPL
ADAVRMLHHPGVGADEAALIDGTHPAWTRIKFDELLAQQLSLKRAHEERRTRAAPAMPRRARDDGAALSARLHAALPFAL
TAAQERVVAEIAHDLTQPHPMQRLLQGDVGSGKTVVAALAAAQAIDAGYQAALMAPTEILAEQHARKLRGWLEPLGVSVA
WLAGSLKAKDKRAALEAAALGTAQLVIGTHAMIQDTVEFARLGLVIVDEQHRFGVEQRLALRAKAANAADGAAGFQPHQL
MMSATPIPRTLAMTYYADLDVSTIDELPPGRTPILTRLVSDARRDEVIGRVREAALAGRQVYWVCPLIEESETLQLQTAV
ETYETLAAALPELKVGLVHGRLAPAEKAAVMDAFSRNDVQLLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRV
GRGTAASVCVLMYSGPLSIAGRARLKTMRETTDGFEIARRDLEIRGPGEFLGARQSGAAMLRFADLENDGWLIEPARDAA
ARLIAAHPEVVAQHLARWLGAREQYLKA

Sequences:

>Translated_748_residues
MPAAAQAARAPRAPRAAPPDALPADTPPASAAKPAKRAAKAASKTVSKAAADAAGAQAAPKAVKTADKLAKLGLTRDIDL
VLHLPMRYEDETTLTPMRELLPGETAQTEGVVFDSEIAYRPRRQLLVKLRDDDGAELVLRFLNFYGSQVKQMAVGQRLRV
RGDVRGGFFGLEIVHPTVKTVDEDAPLPQALTPVYPSTAGVSQAYLRKAIDNALARTPLPELLPPEIARAYLQPLDVPPL
ADAVRMLHHPGVGADEAALIDGTHPAWTRIKFDELLAQQLSLKRAHEERRTRAAPAMPRRARDDGAALSARLHAALPFAL
TAAQERVVAEIAHDLTQPHPMQRLLQGDVGSGKTVVAALAAAQAIDAGYQAALMAPTEILAEQHARKLRGWLEPLGVSVA
WLAGSLKAKDKRAALEAAALGTAQLVIGTHAMIQDTVEFARLGLVIVDEQHRFGVEQRLALRAKAANAADGAAGFQPHQL
MMSATPIPRTLAMTYYADLDVSTIDELPPGRTPILTRLVSDARRDEVIGRVREAALAGRQVYWVCPLIEESETLQLQTAV
ETYETLAAALPELKVGLVHGRLAPAEKAAVMDAFSRNDVQLLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRV
GRGTAASVCVLMYSGPLSIAGRARLKTMRETTDGFEIARRDLEIRGPGEFLGARQSGAAMLRFADLENDGWLIEPARDAA
ARLIAAHPEVVAQHLARWLGAREQYLKA
>Mature_747_residues
PAAAQAARAPRAPRAAPPDALPADTPPASAAKPAKRAAKAASKTVSKAAADAAGAQAAPKAVKTADKLAKLGLTRDIDLV
LHLPMRYEDETTLTPMRELLPGETAQTEGVVFDSEIAYRPRRQLLVKLRDDDGAELVLRFLNFYGSQVKQMAVGQRLRVR
GDVRGGFFGLEIVHPTVKTVDEDAPLPQALTPVYPSTAGVSQAYLRKAIDNALARTPLPELLPPEIARAYLQPLDVPPLA
DAVRMLHHPGVGADEAALIDGTHPAWTRIKFDELLAQQLSLKRAHEERRTRAAPAMPRRARDDGAALSARLHAALPFALT
AAQERVVAEIAHDLTQPHPMQRLLQGDVGSGKTVVAALAAAQAIDAGYQAALMAPTEILAEQHARKLRGWLEPLGVSVAW
LAGSLKAKDKRAALEAAALGTAQLVIGTHAMIQDTVEFARLGLVIVDEQHRFGVEQRLALRAKAANAADGAAGFQPHQLM
MSATPIPRTLAMTYYADLDVSTIDELPPGRTPILTRLVSDARRDEVIGRVREAALAGRQVYWVCPLIEESETLQLQTAVE
TYETLAAALPELKVGLVHGRLAPAEKAAVMDAFSRNDVQLLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVG
RGTAASVCVLMYSGPLSIAGRARLKTMRETTDGFEIARRDLEIRGPGEFLGARQSGAAMLRFADLENDGWLIEPARDAAA
RLIAAHPEVVAQHLARWLGAREQYLKA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=691, Percent_Identity=51.6642547033285, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=393, Percent_Identity=38.1679389312977, Blast_Score=232, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80463; Mature: 80331

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAAQAARAPRAPRAAPPDALPADTPPASAAKPAKRAAKAASKTVSKAAADAAGAQAAP
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KAVKTADKLAKLGLTRDIDLVLHLPMRYEDETTLTPMRELLPGETAQTEGVVFDSEIAYR
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCHHCCC
PRRQLLVKLRDDDGAELVLRFLNFYGSQVKQMAVGQRLRVRGDVRGGFFGLEIVHPTVKT
CHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCEEEEEEECCHHHH
VDEDAPLPQALTPVYPSTAGVSQAYLRKAIDNALARTPLPELLPPEIARAYLQPLDVPPL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCH
ADAVRMLHHPGVGADEAALIDGTHPAWTRIKFDELLAQQLSLKRAHEERRTRAAPAMPRR
HHHHHHHHCCCCCCCCCEEECCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARDDGAALSARLHAALPFALTAAQERVVAEIAHDLTQPHPMQRLLQGDVGSGKTVVAALA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
AAQAIDAGYQAALMAPTEILAEQHARKLRGWLEPLGVSVAWLAGSLKAKDKRAALEAAAL
HHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHC
GTAQLVIGTHAMIQDTVEFARLGLVIVDEQHRFGVEQRLALRAKAANAADGAAGFQPHQL
CHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHH
MMSATPIPRTLAMTYYADLDVSTIDELPPGRTPILTRLVSDARRDEVIGRVREAALAGRQ
HEECCCCCHHHEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VYWVCPLIEESETLQLQTAVETYETLAAALPELKVGLVHGRLAPAEKAAVMDAFSRNDVQ
EEEEECEECCCCCEEHHHHHHHHHHHHHHCCHHHEEHHHCCCCCHHHHHHHHHHCCCCCE
LLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAASVCVLMYSGPLSIA
EHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCCC
GRARLKTMRETTDGFEIARRDLEIRGPGEFLGARQSGAAMLRFADLENDGWLIEPARDAA
HHHHHHHHHHCCCHHHHHHHCCEECCCHHHHCCCCCCCEEEEEEECCCCCEEEECCHHHH
ARLIAAHPEVVAQHLARWLGAREQYLKA
HHHHHCCHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
PAAAQAARAPRAPRAAPPDALPADTPPASAAKPAKRAAKAASKTVSKAAADAAGAQAAP
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KAVKTADKLAKLGLTRDIDLVLHLPMRYEDETTLTPMRELLPGETAQTEGVVFDSEIAYR
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCHHCCC
PRRQLLVKLRDDDGAELVLRFLNFYGSQVKQMAVGQRLRVRGDVRGGFFGLEIVHPTVKT
CHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCEEEEEEECCHHHH
VDEDAPLPQALTPVYPSTAGVSQAYLRKAIDNALARTPLPELLPPEIARAYLQPLDVPPL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCH
ADAVRMLHHPGVGADEAALIDGTHPAWTRIKFDELLAQQLSLKRAHEERRTRAAPAMPRR
HHHHHHHHCCCCCCCCCEEECCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARDDGAALSARLHAALPFALTAAQERVVAEIAHDLTQPHPMQRLLQGDVGSGKTVVAALA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHH
AAQAIDAGYQAALMAPTEILAEQHARKLRGWLEPLGVSVAWLAGSLKAKDKRAALEAAAL
HHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHC
GTAQLVIGTHAMIQDTVEFARLGLVIVDEQHRFGVEQRLALRAKAANAADGAAGFQPHQL
CHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHH
MMSATPIPRTLAMTYYADLDVSTIDELPPGRTPILTRLVSDARRDEVIGRVREAALAGRQ
HEECCCCCHHHEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VYWVCPLIEESETLQLQTAVETYETLAAALPELKVGLVHGRLAPAEKAAVMDAFSRNDVQ
EEEEECEECCCCCEEHHHHHHHHHHHHHHCCHHHEEHHHCCCCCHHHHHHHHHHCCCCCE
LLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAASVCVLMYSGPLSIA
EHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCCCC
GRARLKTMRETTDGFEIARRDLEIRGPGEFLGARQSGAAMLRFADLENDGWLIEPARDAA
HHHHHHHHHHCCCHHHHHHHCCEECCCHHHHCCCCCCCEEEEEEECCCCCEEEECCHHHH
ARLIAAHPEVVAQHLARWLGAREQYLKA
HHHHHCCHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]