| Definition | Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_006350 |
| Length | 4,074,542 |
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The map label for this gene is epsB [H]
Identifier: 53720387
GI number: 53720387
Start: 3315555
End: 3317795
Strand: Reverse
Name: epsB [H]
Synonym: BPSL2778
Alternate gene names: 53720387
Gene position: 3317795-3315555 (Counterclockwise)
Preceding gene: 53720388
Following gene: 53720386
Centisome position: 81.43
GC content: 66.8
Gene sequence:
>2241_bases ATGAATCCCAATCCGACCGGCACATCGACGCCCGCCGACAGCGAAGGCGATACCGACTTCATCGCCGTTCTCGACATCCT GATCGAAGGCCGCTGGCTGATCGCCGCGATCGCGCTCGGTGTTTTCATCGTCGGCGTCGCGTATGCGGTGTTCAGCAAGC CCGTCTATCAGGCCGACATCCTGATCCAGGTGGAGGACAGCCCCGATACGTCCGCCGCGAAGAGCCTGCTCGGCGACGTG TCCTCGCTGTTCGACGTGAAGTCGTCGGCGGCCGCCGAAACGCAGATCCTCGCGTCGCGGCTCGTCGTGTCGCGCGCCGT CGACAATCTGAAACTCTTCATCGACGCGAAGCCGAAGCGTTTCCCGGTGATCGGCCACTGGCTCGCGCGCCGCAGCGAAG GGCTGTCCGATCCGGGGCTCGCGGGGTTCGGCGGCTACGCGTGGGGCCAGGAGCGCATCGATGTCGCGACGTTCGACGTG CCGCGCGCGATGGAGGGCGACACGTTCGAGCTGACGATGCTCGATGCGCGCCGCTACCGCCTCGACGGCGGCGATCTCGA GCGCGGCGCCGTGGGCGTCGTCGGCCGGCTCGAACGCATCGCGGCGAAGGGCGGGCCGATCGCGCTGCGCGTCGACGCGT TCGCCGCGAAGCCGGGCGCGACGTTCGTGCTCGTGCGCCATTCCCGCCTGCGTACGATCGAGGCGTTGCAGGACAACCTC GACGTGCAGGAGCGCGTCAAGCAGTCCGACGTCGTCGTCGCGAGCCTGCGCGACACCGATCCCGATCTCGTGAGCCGCGC GCTCAATGAAATCGGGCGGCAATACATCGCGCAGAACATTCAGCGAAAGTCGGCGGAAGCCGCGCAATCGCTCGAGTTCC TGAATGGGCAACTGCCCACGCTCAAGCAGCAGTTGACCGATTCGGAAGCGCGACTGACGAAACTGCGCGACGAGCACGGC AGCGTCGATCTGACCGAGGAGGCGAAGCTCGTGCTCGCGCAATCGGCCGACGCGAAGACGCGTCTGCTCGAATTGCAGCA AAAGCGGCGGGAGCTGCTGTCGCGCTTCATGCCGAAGCACCCGAGCGTCGTCGCGATCGATCAGCAGATCGCCGCGCTCG ACGGCTATCGCGGCACGGCCGAGCAGCAGATCAAGCGGCTGCCGGCGCTGCAGCAACAGTTCGTGCGGCTGATGCTCGAC GTGAAGGTCAATACCGATCTCTATACGGCGTTGCTCAACAACATGCAGCAGTTGCAGCTCGTGCGCGCGGGCAAGGTCGG CAACGTGCGGCTCGTCGATACGGCGGCGGTGCCGGAAGTCCCCGTCAAGCCGAAGAAAGCGCTCGTCGCGCTCGCGTCGC TGCTGCTCGGCGTGCTCGCCGGCTGCGGCACGGCGGTTGGCCGCTCGATGCTGTTCCACGGCATCTCCGATCCGAACGAG ATCGAGCGGCGCCTCGGCTTGAGCGTCTATGCGACCGTGCCCCGCAGCGATCGGCAACGGGCGCTGACCGAGCGCGCGAA GCACAAGGCGCGCGCGCTGTCGCTGCTGTGCGTCGCGCATCCGGACGAGCCGGCCGTCGAGAGCCTGCGCAGCCTGCGCA CCGCGCTGCAATTCGCGATGCTCGATGCAAAAAACAACGTCGTCGTGATCGCGGGTCCCGCGCCGGGCGTGGGCAAGTCG TTCGTGTCGGCCAATCTCGCCGCGGTGCTGACGATGGCGGGCAAGCGCGTGCTGCTGATCGACGGCGACATTCGCAAAGG ACATCTGAACGACTATCTCGGCCTCGCGCGCGGCAAGGGCTTTTCCGAACTGATCGCGGGCTCGGCGCAGCCGGACGACG TGCTGCATCGCGACGTGATCGCCGGGCTCGATTTCATCTCGACGGGCGCGATGCCGAAGAATCCGGCCGAGTTGCTGCTC AATGCGCGCGTGTCGACGTTGATCGACACTTTCTCGCAGCGTTACGACGCCGTCGTGATCGATTCGCCGCCGGTGCTGGC GGTGGCTGACACGGGCATTCTCGCCGCGACGGCGGGCACGGCGTTCCTCGTCACGCTCGCCGGCTCGACGAAGCTCGGCG AGATCGCCGAATCGGCGAAGCGGCTCGCGCAGAACGGCGTGCGCCTGAGTGGCGTGGTGTTCAACGGCATCAATCCGCGC CTCGGGCAGTACGGCTACGGCTCGAAGTACGGCGGCTATCGCTACGTCGCATACGAATACGGAGCGAAGCGCGATGCCTG A
Upstream 100 bases:
>100_bases CCGCGCGGCTGCTCGAACTCGGCGTGAACGGCTGGCTGTCGCGGCTGCGGCTCGTGTGAGCGCGCGCGGCGCGTAGAACC GAATCTCCAAGACCCCATAC
Downstream 100 bases:
>100_bases CGCGAACATGCGCGACGAACGCCGTGGCGACGGCGGCCGGCCGGTGCCGGCCGACGGGCGATGCGCGCGCGCGAACGCGA GGACGCGACGATGATTCGCG
Product: putative tyrosine-protein kinase involved in EPS biosynthesis
Products: ADP; protein tyrosine phosphate [C]
Alternate protein names: EPS I polysaccharide export protein epsB [H]
Number of amino acids: Translated: 746; Mature: 746
Protein sequence:
>746_residues MNPNPTGTSTPADSEGDTDFIAVLDILIEGRWLIAAIALGVFIVGVAYAVFSKPVYQADILIQVEDSPDTSAAKSLLGDV SSLFDVKSSAAAETQILASRLVVSRAVDNLKLFIDAKPKRFPVIGHWLARRSEGLSDPGLAGFGGYAWGQERIDVATFDV PRAMEGDTFELTMLDARRYRLDGGDLERGAVGVVGRLERIAAKGGPIALRVDAFAAKPGATFVLVRHSRLRTIEALQDNL DVQERVKQSDVVVASLRDTDPDLVSRALNEIGRQYIAQNIQRKSAEAAQSLEFLNGQLPTLKQQLTDSEARLTKLRDEHG SVDLTEEAKLVLAQSADAKTRLLELQQKRRELLSRFMPKHPSVVAIDQQIAALDGYRGTAEQQIKRLPALQQQFVRLMLD VKVNTDLYTALLNNMQQLQLVRAGKVGNVRLVDTAAVPEVPVKPKKALVALASLLLGVLAGCGTAVGRSMLFHGISDPNE IERRLGLSVYATVPRSDRQRALTERAKHKARALSLLCVAHPDEPAVESLRSLRTALQFAMLDAKNNVVVIAGPAPGVGKS FVSANLAAVLTMAGKRVLLIDGDIRKGHLNDYLGLARGKGFSELIAGSAQPDDVLHRDVIAGLDFISTGAMPKNPAELLL NARVSTLIDTFSQRYDAVVIDSPPVLAVADTGILAATAGTAFLVTLAGSTKLGEIAESAKRLAQNGVRLSGVVFNGINPR LGQYGYGSKYGGYRYVAYEYGAKRDA
Sequences:
>Translated_746_residues MNPNPTGTSTPADSEGDTDFIAVLDILIEGRWLIAAIALGVFIVGVAYAVFSKPVYQADILIQVEDSPDTSAAKSLLGDV SSLFDVKSSAAAETQILASRLVVSRAVDNLKLFIDAKPKRFPVIGHWLARRSEGLSDPGLAGFGGYAWGQERIDVATFDV PRAMEGDTFELTMLDARRYRLDGGDLERGAVGVVGRLERIAAKGGPIALRVDAFAAKPGATFVLVRHSRLRTIEALQDNL DVQERVKQSDVVVASLRDTDPDLVSRALNEIGRQYIAQNIQRKSAEAAQSLEFLNGQLPTLKQQLTDSEARLTKLRDEHG SVDLTEEAKLVLAQSADAKTRLLELQQKRRELLSRFMPKHPSVVAIDQQIAALDGYRGTAEQQIKRLPALQQQFVRLMLD VKVNTDLYTALLNNMQQLQLVRAGKVGNVRLVDTAAVPEVPVKPKKALVALASLLLGVLAGCGTAVGRSMLFHGISDPNE IERRLGLSVYATVPRSDRQRALTERAKHKARALSLLCVAHPDEPAVESLRSLRTALQFAMLDAKNNVVVIAGPAPGVGKS FVSANLAAVLTMAGKRVLLIDGDIRKGHLNDYLGLARGKGFSELIAGSAQPDDVLHRDVIAGLDFISTGAMPKNPAELLL NARVSTLIDTFSQRYDAVVIDSPPVLAVADTGILAATAGTAFLVTLAGSTKLGEIAESAKRLAQNGVRLSGVVFNGINPR LGQYGYGSKYGGYRYVAYEYGAKRDA >Mature_746_residues MNPNPTGTSTPADSEGDTDFIAVLDILIEGRWLIAAIALGVFIVGVAYAVFSKPVYQADILIQVEDSPDTSAAKSLLGDV SSLFDVKSSAAAETQILASRLVVSRAVDNLKLFIDAKPKRFPVIGHWLARRSEGLSDPGLAGFGGYAWGQERIDVATFDV PRAMEGDTFELTMLDARRYRLDGGDLERGAVGVVGRLERIAAKGGPIALRVDAFAAKPGATFVLVRHSRLRTIEALQDNL DVQERVKQSDVVVASLRDTDPDLVSRALNEIGRQYIAQNIQRKSAEAAQSLEFLNGQLPTLKQQLTDSEARLTKLRDEHG SVDLTEEAKLVLAQSADAKTRLLELQQKRRELLSRFMPKHPSVVAIDQQIAALDGYRGTAEQQIKRLPALQQQFVRLMLD VKVNTDLYTALLNNMQQLQLVRAGKVGNVRLVDTAAVPEVPVKPKKALVALASLLLGVLAGCGTAVGRSMLFHGISDPNE IERRLGLSVYATVPRSDRQRALTERAKHKARALSLLCVAHPDEPAVESLRSLRTALQFAMLDAKNNVVVIAGPAPGVGKS FVSANLAAVLTMAGKRVLLIDGDIRKGHLNDYLGLARGKGFSELIAGSAQPDDVLHRDVIAGLDFISTGAMPKNPAELLL NARVSTLIDTFSQRYDAVVIDSPPVLAVADTGILAATAGTAFLVTLAGSTKLGEIAESAKRLAQNGVRLSGVVFNGINPR LGQYGYGSKYGGYRYVAYEYGAKRDA
Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the in
COG id: COG3206
COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the etk/wzc family [H]
Homologues:
Organism=Escherichia coli, GI87082032, Length=744, Percent_Identity=35.8870967741936, Blast_Score=432, Evalue=1e-122, Organism=Escherichia coli, GI1787216, Length=732, Percent_Identity=32.9234972677596, Blast_Score=415, Evalue=1e-117,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002586 - InterPro: IPR005702 - InterPro: IPR005700 - InterPro: IPR003856 [H]
Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]
EC number: 2.7.1.112 [C]
Molecular weight: Translated: 80343; Mature: 80343
Theoretical pI: Translated: 9.31; Mature: 9.31
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNPNPTGTSTPADSEGDTDFIAVLDILIEGRWLIAAIALGVFIVGVAYAVFSKPVYQADI CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE LIQVEDSPDTSAAKSLLGDVSSLFDVKSSAAAETQILASRLVVSRAVDNLKLFIDAKPKR EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC FPVIGHWLARRSEGLSDPGLAGFGGYAWGQERIDVATFDVPRAMEGDTFELTMLDARRYR CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECHHEE LDGGDLERGAVGVVGRLERIAAKGGPIALRVDAFAAKPGATFVLVRHSRLRTIEALQDNL CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHCC DVQERVKQSDVVVASLRDTDPDLVSRALNEIGRQYIAQNIQRKSAEAAQSLEFLNGQLPT CHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH LKQQLTDSEARLTKLRDEHGSVDLTEEAKLVLAQSADAKTRLLELQQKRRELLSRFMPKH HHHHHCCHHHHHHHHHHHCCCEEECCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC PSVVAIDQQIAALDGYRGTAEQQIKRLPALQQQFVRLMLDVKVNTDLYTALLNNMQQLQL CCEEEECHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHH VRAGKVGNVRLVDTAAVPEVPVKPKKALVALASLLLGVLAGCGTAVGRSMLFHGISDPNE HHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHH IERRLGLSVYATVPRSDRQRALTERAKHKARALSLLCVAHPDEPAVESLRSLRTALQFAM HHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHH LDAKNNVVVIAGPAPGVGKSFVSANLAAVLTMAGKRVLLIDGDIRKGHLNDYLGLARGKG EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCC FSELIAGSAQPDDVLHRDVIAGLDFISTGAMPKNPAELLLNARVSTLIDTFSQRYDAVVI HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE DSPPVLAVADTGILAATAGTAFLVTLAGSTKLGEIAESAKRLAQNGVRLSGVVFNGINPR CCCCEEEEECCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC LGQYGYGSKYGGYRYVAYEYGAKRDA CCCCCCCCCCCCEEEEEEECCCCCCC >Mature Secondary Structure MNPNPTGTSTPADSEGDTDFIAVLDILIEGRWLIAAIALGVFIVGVAYAVFSKPVYQADI CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE LIQVEDSPDTSAAKSLLGDVSSLFDVKSSAAAETQILASRLVVSRAVDNLKLFIDAKPKR EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC FPVIGHWLARRSEGLSDPGLAGFGGYAWGQERIDVATFDVPRAMEGDTFELTMLDARRYR CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECHHEE LDGGDLERGAVGVVGRLERIAAKGGPIALRVDAFAAKPGATFVLVRHSRLRTIEALQDNL CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHCC DVQERVKQSDVVVASLRDTDPDLVSRALNEIGRQYIAQNIQRKSAEAAQSLEFLNGQLPT CHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH LKQQLTDSEARLTKLRDEHGSVDLTEEAKLVLAQSADAKTRLLELQQKRRELLSRFMPKH HHHHHCCHHHHHHHHHHHCCCEEECCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC PSVVAIDQQIAALDGYRGTAEQQIKRLPALQQQFVRLMLDVKVNTDLYTALLNNMQQLQL CCEEEECHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHH VRAGKVGNVRLVDTAAVPEVPVKPKKALVALASLLLGVLAGCGTAVGRSMLFHGISDPNE HHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHH IERRLGLSVYATVPRSDRQRALTERAKHKARALSLLCVAHPDEPAVESLRSLRTALQFAM HHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHH LDAKNNVVVIAGPAPGVGKSFVSANLAAVLTMAGKRVLLIDGDIRKGHLNDYLGLARGKG EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCC FSELIAGSAQPDDVLHRDVIAGLDFISTGAMPKNPAELLLNARVSTLIDTFSQRYDAVVI HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE DSPPVLAVADTGILAATAGTAFLVTLAGSTKLGEIAESAKRLAQNGVRLSGVVFNGINPR CCCCEEEEECCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC LGQYGYGSKYGGYRYVAYEYGAKRDA CCCCCCCCCCCCEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; a protein tyrosine [C]
Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11823852 [H]