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The map label for this gene is otsA [H]

Identifier: 53720016

GI number: 53720016

Start: 2913647

End: 2915056

Strand: Reverse

Name: otsA [H]

Synonym: BPSL2410

Alternate gene names: 53720016

Gene position: 2915056-2913647 (Counterclockwise)

Preceding gene: 53720017

Following gene: 53720014

Centisome position: 71.54

GC content: 68.51

Gene sequence:

>1410_bases
ATGAGCCGTCTCATCATCGTCTCGAATCGGGTCGCGCCGATCTCCGAAGGAGAACCCGCGGCCGGCGGCCTCGCGATCGG
CGTCTACGACGCGCTGAAGGAAACGGGCGGCATGTGGTTCGGCTGGAGCGGCGAGGTGATCGCGTCGGGCGTGCCGCAGA
TCCGCATCGAGGAGCACGGCCCCGTCACGTTCGCGACGATCGGGCTGTCGCGCCGCGACTACGACCAGTACTACCGAGGC
TTTTCGAACGCGACGCTCTGGCCCGCGTTCCACTATCGCGCGGACCTGATCCAGTTCGACCGCCACGAGTTCGAAGGCTA
TTCGCGCGTGAACGTGTGGCTCGCGCAGCAGCTCGTGCCGCTGCTGCGCGATGACGACGTGATCTGGGTGCACGACTATC
ATCTGATTCCGTTCGCGCGGGCGCTGCGCACGGCGGGCGTGAAGAACCGCATCGGTTTTTTCCTGCATATTCCGTTTCCG
GCGGCGCAGGTGCTCGTCAACGTGCCGCCGCATCGCGAGCTGGTCGAGGCGCTGTGCTCGTTCGATCTGCTCGGCTTTCA
GACCGACACCGATTTGCGCGCGTTCTTCGAGTACGTCGAATACGAGGCGGGCGGCACGGTCGATCGCGCCGCGCATCCGG
CGCGCGTCGACGCGTTCGGCCGCACGCTGCGCGCGGCCGCGTATCCGATCGGCGTGTATCCGGACGAGATCGCCGCGCTC
GCGAAGGCGGGCGAGAACGGCCGCGCGGTGAAGTCGCTCGCGGCCTCGCTGCGCGGGCGGCAGCTCGTGATGAGCGTCGA
CCGGCTCGATTACTCGAAGGGGCTCGTCGAGCGCTTTCGCGCATTCGAGAAGCTGCTCGAGCACGAGACGTCGTTTCGCA
ATCGCGTGTCGTTCCTGCAGATCGCGCCGTCCACGCGCGCCGATCTGCGCGCGTACCAGGACATCCGCCGGCAGCTCGAA
GGCGAATCGGGGCGCATCAACGGCCGTTTCGCGGAGCTCGACTGGGCGCCGATCCTCTATATCCATCGGCAGTACGAACG
GCCGGTGCTCGCCGCGCTATACCGGCTCGCGCGCGTCGGGTACGTGACGCCGCTGCGCGACGGGATGAATCTCGTCGCGA
AGGAGTACGTGTCCGCGCAGGATCCGGACGATCCGGGCGTGCTCGTGCTGTCGCGCTTCGCGGGCGCCGCGTGCGAACTC
ACCGGCGCGTTGATCGTCAATCCGATCGACATCGGCGGGATGGCCGACGCGCTGTCGCGCGCGCTGTCGATGCCGCTCGC
CGAGCGGCGCGCGCGCCACGCCGACATGCTCGCGCGGTTGCGCGAGAACAACGTGTCGGTGTGGCGCGACCACTTCCTGC
GCGATCTCGGGCGGCAGCGCGCGGCGTCGGGGGCCGGCCGGGGTCGTTAG

Upstream 100 bases:

>100_bases
AGGTCGGTGCGGGCGACACGACGGCGCGCGCGCGCGTCGATTCGGTCGCCGCGTTGCGCGCGCAGCTCGCGCGCTGGATC
GCCGCGGGGCGCGCGCCCGC

Downstream 100 bases:

>100_bases
GCGTGCGCGACGATGCGCGCGTGCGGCTTTAAGCGACGCGCTCGTCGTCCGACGACGAATCGTCGTCGTCGCTATGGTCG
TGCGCGGGCGCGGGCGCCGG

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHGPVTFATIGLSRRDYDQYYRG
FSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFP
AAQVLVNVPPHRELVEALCSFDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQIAPSTRADLRAYQDIRRQLE
GESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVGYVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACEL
TGALIVNPIDIGGMADALSRALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGRQRAASGAGRGR

Sequences:

>Translated_469_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHGPVTFATIGLSRRDYDQYYRG
FSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFP
AAQVLVNVPPHRELVEALCSFDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQIAPSTRADLRAYQDIRRQLE
GESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVGYVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACEL
TGALIVNPIDIGGMADALSRALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGRQRAASGAGRGR
>Mature_468_residues
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHGPVTFATIGLSRRDYDQYYRGF
SNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFPA
AQVLVNVPPHRELVEALCSFDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAALA
KAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQIAPSTRADLRAYQDIRRQLEG
ESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVGYVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACELT
GALIVNPIDIGGMADALSRALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGRQRAASGAGRGR

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=471, Percent_Identity=52.0169851380042, Blast_Score=477, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI115533558, Length=421, Percent_Identity=28.5035629453682, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115533560, Length=421, Percent_Identity=28.5035629453682, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71987012, Length=416, Percent_Identity=28.125, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319602, Length=470, Percent_Identity=31.4893617021277, Blast_Score=264, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323537, Length=435, Percent_Identity=26.6666666666667, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320279, Length=403, Percent_Identity=25.0620347394541, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323917, Length=378, Percent_Identity=26.4550264550265, Blast_Score=146, Evalue=7e-36,
Organism=Drosophila melanogaster, GI19920676, Length=489, Percent_Identity=35.5828220858896, Blast_Score=275, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52478; Mature: 52347

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHG
CCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCHHHCCCCEEEEECCC
PVTFATIGLSRRDYDQYYRGFSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVP
CEEEEEECCCCCCHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFPAAQVLVNVPPHRELVEALCS
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEEECCCHHHHHHHHHC
FDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
CHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQ
HHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
IAPSTRADLRAYQDIRRQLEGESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVG
ECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEHHHHCCHHHHHHHHHHHHC
YVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACELTGALIVNPIDIGGMADALSR
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHEECCEEEECCCCCCCHHHHHHH
ALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGRQRAASGAGRGR
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHG
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCHHHCCCCEEEEECCC
PVTFATIGLSRRDYDQYYRGFSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVP
CEEEEEECCCCCCHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFPAAQVLVNVPPHRELVEALCS
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEEECCCHHHHHHHHHC
FDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
CHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQ
HHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
IAPSTRADLRAYQDIRRQLEGESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVG
ECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEHHHHCCHHHHHHHHHHHHC
YVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACELTGALIVNPIDIGGMADALSR
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHEECCEEEECCCCCCCHHHHHHH
ALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGRQRAASGAGRGR
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA