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The map label for this gene is serC [H]

Identifier: 53719828

GI number: 53719828

Start: 2663718

End: 2664812

Strand: Reverse

Name: serC [H]

Synonym: BPSL2219

Alternate gene names: 53719828

Gene position: 2664812-2663718 (Counterclockwise)

Preceding gene: 53719829

Following gene: 53719827

Centisome position: 65.4

GC content: 67.31

Gene sequence:

>1095_bases
ATGCATCGCAATCAACTGAATTTCTCCGGCGGCCCCGGCGCGCTGCCGGATACCGTGCTCGAACAGGTGCGGCAAGCGGT
GGTGGAGCTGCCGGAAACCGGCTTGTCGGTGCTCGGCATGAGCCATCGCTCGAGCTGGTTCTCGAGTCTGCTCGCGCAGG
CGCAGGCGGATCTGCGCGATCTGCTGGGCATTCCGGACGAGTACGGCGTCGTGTTCCTGCAAGGCGGCAGCAGCCTGCAG
TTCTCGATGATCCCGATGAATTTCTCGCGGCCGGGCGCGGCCGCGCCCGAGTACGTGACGACGGGCTACTGGAGCCGCAA
GGCGATCGGCGAGGCGTCGCGCGTGGCCGCGATGCGCGTGGTCTGGGACGGCGCGGCGAGCGGCTACCGGACGCTGCCGT
CGCTCGCCGCGCTCGACTGGGACGCGCGCGCGCCGTTTCGTCACTACGTATCCAACGAGACCGTCGAAGGGCTGCAGTTT
CCCGACGCGGCGGATCTGCCCGGCAGCCCGCTGATCGCGGACATGTCGTCGGATTTCATGTCGAGGCCGTTCGACGTGCG
CGCGTACGGCATGGTCTACGCGCACGCGCAGAAGAATCTCGGGCCTGCCGGCGTGACGGTCGCGATCATCCGGCGCGCGC
TGCTCGAGCGCGTTCCGGACACGCTGCCGCCGATGCTCGATTTCCGCACGCACGTCGAGCATCGGTCGAACTACAACACG
CCGCCCGTGTTCGCGATCTACGTGATGGCGCTCGTGCTGCGCTGGATTAGGGACGAAATCGGCGGCGTGCATGCGATGCG
CGACATCAATGCGCGCAAGGCCGCCATGCTCTATGCGACGCTCGATGCGTTGAACGAAGTGATCGACTGCCATGCGCACA
GGGCGGCGCGCTCGACGATGAACGTCGCGTTCCGTTTCAGGCAGCCGCGGCTCGACACGCTATTCAAGGAGCAGTCCACG
GAGGCGGGCTTCTGCGGCCTGAGCGGGCACCGCTCGATCGGCGGCATCCGCGCGTCGCTCTACAACGCCGTATCGGAGCA
GGCGGTGAGCCGGCTGTGCGCGTTCCTGAAGGACTTCGCGATCCGGCACGCGTGA

Upstream 100 bases:

>100_bases
CTGAACGCCGCGCTCAGGCGGGGCGCGACGCGTCCGTCCGCGGGCTATCTGCAGAAGTGATCCGATTCCGGTTCTCACCT
TGCCTCGGGAGTGTCGTCAG

Downstream 100 bases:

>100_bases
CGCGCGGCCGGCACCCGGCGCGCCGCCGCGCGCGTCGGCGCGACACTTCGACGGCGTCGATTCAACCCGAAGGAGATTGA
CCATGCTTTCCATCATCGTG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDEYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA

Sequences:

>Translated_364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDEYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA
>Mature_364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDEYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=367, Percent_Identity=40.0544959128065, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI10863955, Length=362, Percent_Identity=37.5690607734807, Blast_Score=243, Evalue=2e-64,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=38.6740331491713, Blast_Score=254, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=37.9120879120879, Blast_Score=273, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=34.8837209302326, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=40.771349862259, Blast_Score=273, Evalue=2e-73,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40054; Mature: 40054

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLGIPDEYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRV
HHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHCCCCHHHHHCHHHHHHHHHH
VWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQFPDAADLPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
SRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCCCEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTM
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQPRLDTLFKEQSTEAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFA
HHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRHA
HCCC
>Mature Secondary Structure
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLGIPDEYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYVTTGYWSRKAIGEASRVAAMRV
HHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHCCCCHHHHHCHHHHHHHHHH
VWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQFPDAADLPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
SRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCCCEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTM
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQPRLDTLFKEQSTEAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFA
HHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRHA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA