Click here to switch to the map view.

The map label for this gene is alr

Identifier: 53719788

GI number: 53719788

Start: 2616342

End: 2617412

Strand: Reverse

Name: alr

Synonym: BPSL2179

Alternate gene names: 53719788

Gene position: 2617412-2616342 (Counterclockwise)

Preceding gene: 53719791

Following gene: 53719787

Centisome position: 64.24

GC content: 70.68

Gene sequence:

>1071_bases
ATGCCGCGCCCGATTTCCGCCACGATCCACACCGCAGCTCTCGCGAACAACCTCTCCGTCGTGCGCCGCCACGCCGCCCA
GTCGAAGGTCTGGGCGATCGTCAAGGCGAACGCGTATGGGCACGGTCTCGCGCGCGTCTTTCCCGGGCTGCGCGGCACCG
ACGGCTTCGGCCTGCTCGACCTCGACGAGGCCGTGAAGCTGCGCGAACTGGGCTGGGCGGGGCCGATCCTGCTGCTCGAG
GGCTTCTTCCGGTCGACCGACATCGACGTGATCGACCGCTACAGCCTGACGACCGCGGTGCACAACGACGAGCAGATGCG
CATGCTCGAGACCGCGCGGCTGTCGAAGCCCGTGAACGTCCAGCTGAAGATGAACAGCGGCATGAACCGGCTCGGCTACA
CGCCCGAGAAGTACCGGGCCGCCTGGGAGCGCGCGCGCGCATGCCCGGGCATCGGCCAGATCACGTTGATGACCCATTTT
TCGGACGCCGACGGCGAACGCGGCGTGGCCGAGCAGATGGCGACGTTCGAGCGCGGCGCGCAAGGCATCGCCGGCGCGCG
CAGCTTCGCGAACTCGGCCGCCGTGCTCTGGCACCCGTCGGCGCACTTCGACTGGGTGCGGCCCGGCATCATGCTGTACG
GCGCGTCGCCGTCCGGCCGTGCGGCGGACATCGCCGACCGGGGCCTGAAGCCGACGATGACGCTCGCCTCCGAGCTGATC
GCCGTGCAGACGCTCGCGAAAGGGCAGGCGGTCGGCTACGGATCGATGTTCGTCGCCGAGGACACGATGCGCATCGGCGT
CGTCGCGTGCGGCTATGCGGACGGCTATCCGCGGATCGCGCCCGAGGGCACGCCCGTCGTCGTCGACGGCGTGCGCACGC
GGATCGTCGGCCGCGTGTCGATGGACATGCTGACCGTCGATCTCACGCCCGTGCCGCAGGCGGGCGTCGGCGCGCGCGTC
GAGCTGTGGGGCGAGACGCTGCCGATCGACGACGTCGCCGCGCGCTGCATGACGGTCGGCTACGAGCTGATGTGCGCGGT
CGCGCCGCGCGTGCCCGTGCGTGCCGAGTAA

Upstream 100 bases:

>100_bases
CGGACTAGCAAGATCCCCCGATCGTTCCGCGCGTTTCCGGCGTCGTGCCCAAAAGGCGCGATAAGCTGATGATTCGCAAG
CGTCTTTACAGAAATTTCCT

Downstream 100 bases:

>100_bases
GGGCGCGCGCATGGCCAAGCAGAAGACGGTATTCGTCTGCACCGAGTGCGGCGGGCAGACGCCGAAGTGGCAGGGTCAAT
GCCCGTCGTGCCACGCATGG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MPRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHF
SDADGERGVAEQMATFERGAQGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELI
AVQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARV
ELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE

Sequences:

>Translated_356_residues
MPRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHF
SDADGERGVAEQMATFERGAQGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELI
AVQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARV
ELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
>Mature_355_residues
PRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLEG
FFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHFS
DADGERGVAEQMATFERGAQGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELIA
VQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARVE
LWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=58.6402266288952, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1790487, Length=352, Percent_Identity=45.4545454545455, Blast_Score=297, Evalue=8e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_BURM7 (A3MKW5)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001080901.1
- ProteinModelPortal:   A3MKW5
- SMR:   A3MKW5
- GeneID:   4893421
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_1350
- TIGR:   BMA10247_1350
- HOGENOM:   HBG712172
- OMA:   WGKQVLA
- ProtClustDB:   PRK00053
- BioCyc:   BMAL320389:BMA10247_1350-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 38335; Mature: 38203

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 35-35 ACT_SITE 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCEEE
LDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNV
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCEEEEEEECCCHHHHHHHHHHCCCCCEE
QLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHFSDADGERGVAEQMATFERGA
EEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCC
QGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELI
CHHHHHHHHCCCEEEEECCCCCCCEECCCEEEEECCCCCCCCHHHHCCCCCHHHHHHHHH
AVQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVS
HHHHHHCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCCCCCCCCEEECCHHHHEEHEEE
MDMLTVDLTPVPQAGVGARVELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
EEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure 
PRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLD
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCEEE
LDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNV
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCEEEEEEECCCHHHHHHHHHHCCCCCEE
QLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHFSDADGERGVAEQMATFERGA
EEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCC
QGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELI
CHHHHHHHHCCCEEEEECCCCCCCEECCCEEEEECCCCCCCCHHHHCCCCCHHHHHHHHH
AVQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVS
HHHHHHCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCCCCCCCCEEECCHHHHEEHEEE
MDMLTVDLTPVPQAGVGARVELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE
EEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA