| Definition | Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_006350 |
| Length | 4,074,542 |
Click here to switch to the map view.
The map label for this gene is mrcA [H]
Identifier: 53719715
GI number: 53719715
Start: 2527868
End: 2530426
Strand: Reverse
Name: mrcA [H]
Synonym: BPSL2104
Alternate gene names: 53719715
Gene position: 2530426-2527868 (Counterclockwise)
Preceding gene: 53719720
Following gene: 53719710
Centisome position: 62.1
GC content: 68.11
Gene sequence:
>2559_bases GTGCTCGAGGCGCGCCTCGTGCGCCGCCCATCCGACATGCCTATTATCAAACGACCGCCTTCCTCCCGCGCCACGAACGA GCACCATTATTCGCTGCGACGCTCGCCGGCCGGCGCCTATTACACCGATGACGACGATGATGACGAGCGCGCGCCGCGCC GCACGGGCCGCGACGGCGGCTCGCGCACGTTCGGCTCGCGCGTCGCGCTGTGGTTCGCCGGGCTCTTCGCGACGCTGCTC GTCGTCGGCGCGCTGATCGTAGGCTATGCGCTGGTGGTGATGGGGCCGCAACTGCCGTCGCTCGACGCGCTCACGAATTA CCAGCCGAAGGTGCCGCTGCGCGTGTACAGCGCGGACCACGTGCTGCTCGGCGAATTCGGCGAGGAGCGCCGCAGCCTCG TGCGCTTCGCGGACATCCCCGACGTGATGAAGAAGGCGGTGCTCGCGATCGAGGATTATCGCTTCTACGAGCACGGCGGC GTGGATTTCGTCGGCATCCTGCGCGCGGGTGTGGCCGATCTGCTGCATGGCGGCGCGCGGCAGGGCGCGAGCACGATCAC GATGCAGGTCGCGCGCAACTTCTTCCTGTCGAGCGAGAAGACGTACACGCGCAAGATCTACGAGATGCTGCTCGCGTACA AGATCGAAAAGGCGCTGACGAAGGACCAGATCCTCGAGCTGTACATGAACCAGATCTATCTGGGCCAGCGCGCGTACGGC TTCGCGGCCGCCGCGCGCGTGTATTTCGGCAAGGACCTGAAGGACGTCACGCTCGCCGAGGCCGCGATGCTCGCGGGGCT GCCGAAGGCGCCGTCCGCGTACAACCCGGTCGTCAACCCGAAGCGCGCGAAGGTGCGTCAGGAGTACATCCTGAAGCGGA TGCTGGAGATCGGCTACATCACGCAGCAGCAGTACGATCAGGCGGTGAAGGAGGAAATCCACGTGCGCACGCCGGGCAAC CAGTACGCGGTGCACGGCGAGTACGTCGCCGAAATGGTGCGGCAGATGATGTATGCGCAGTACAAGGACGAAACCTACAC GCGCGGCCTGACCGTCACGACGACGATCAACGCGGCCGACCAGGAAGCCGCGTACCAGGCGGTGCGCCGCGGGATCATGG ATTACGAGCGCCGCCACGGCTATCGCGGGCCGGAAGGCTTCGTCGCGCTGCCGCCCGCCGGCGACGAGCGCGACGAGGCG ATCGACGACGCGCTCGCGGATCATCCCGACAACGGCGATCTGCAGTCGGCCGTCGTGCTCGCCGTCTCGCCGACGGCGGT CGACGTGCAGTTCGTCGGCGGCGCGACGGCGACGATCAACGGCGCCGGGCTGCGTTTCGCGGCCGGTGCGTTGAGCGCGC GCGCGTCGGCCGCGCTGAAGATCAAGCCGGGTTCGATCGTGCGCGTGATGAAGGACGCGAGGAGCGCATGGCAGATCGTG CAGTTGCCGCAGGTCGAGGGCGCGCTCGTCGCGGTCGCGCCGCAGGACGGCGCGATCCGCTCGCTCGTCGGCGGCTTCGA TTTCAACAAGAGCAAGTTCAACCACGTGACGCAGGCATGGCGGCAGCCGGGCTCGTCGTTCAAGCCGTTCATCTATTCGG CGTCGCTCGAAAAGGGCCTCGGGCCCGCGACGATCATCAACGACGCGCCGCTCTATTTCCCGCCGAGCGTGCCGGGCGGC CAGCCGTGGGAGCCGAAGGACGACGATCAGCCGGACGGCCCGATGCCGATGCGCACCGCGCTGCAGCGCTCGAAGAACCT CGTGTCGATCCGGATTCTGGCGTCGATCGGCACGTCGTATGCGCAGGACTACGTGACGCAGCGCTTCGGCTTCGATCCCG CGAAGACGCCGCCGTATCTGCCGATGGCGCTCGGCGCGGGCCTCGTCACGCCGCTGCAGCTCGCGGCGGGCTACGCGGTG TTCGCCAACGGCGGCTTCAAGGTCGATCCGTATCTGATCGCCGAAGTCGACGACGCGCGCGGGCAGGCGCTGCAAAAGGC GCAGCCGGTGGTCGCGGGCGCGAGCGCGACGCGCACGATCGACGCGCGCAACGCCTACGTGATGAACAGCCTGCTGCACA CCGTCGCGACGGCGGGCACGGGCGCCGGCACGAACGCGCTCGGCCGCGGCGACCTGCAGGGCAAGACCGGCACGACGAAC GAGGCGAAGGACGGCTGGTTCGCCGGCTATCAGCAGTCGCTCGTCGCCGTTGCATGGATGGGCTTCGATCAGCCGAAGAG TCTCGGCAGCCGTGAATTCGGCGCGCAGCTCGCGTTGCCGATTTGGGTGAATTACATGCGCACCGCGCTCAACGGCGTGC CGGAGCAGCAGATGGCGATGCCGGACGGGCTGACGACGATCGACGGCGAGCTGTATTACGCGGATCGCACGCCGGGCGCG GGCTTCGTCGCGAGCGTCGATTTCAATCCGGCCGCGAGCCCGACCGTGAGCGCGAACGACGCGCTCGGCTCGGCGGGCGC GGCGGGCCTGACGCCGCCGCCCGTGACGCCGGAGGAGAAGCGGCAGATCATCGACATGTTCGAAGGCAACAAGCCTTGA
Upstream 100 bases:
>100_bases TGCGGACCGGATAGCCGTATGGACCGACGCGCGCCGGGAACCGTCGACGTGATACGCTCCACGACGCTACGTCCATCGAT TCCATGCACGCGTTCAGCGC
Downstream 100 bases:
>100_bases TCGGCGATCGGCGATGCGGATCGCATGACGAGGAAACGGGCGCCGGCGGCGCCCGTTTTTTTGGCCGGCGCGGTTTGGCG GGCGGCGTCGGCGCTGCCTG
Product: putative penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 852; Mature: 852
Protein sequence:
>852_residues MLEARLVRRPSDMPIIKRPPSSRATNEHHYSLRRSPAGAYYTDDDDDDERAPRRTGRDGGSRTFGSRVALWFAGLFATLL VVGALIVGYALVVMGPQLPSLDALTNYQPKVPLRVYSADHVLLGEFGEERRSLVRFADIPDVMKKAVLAIEDYRFYEHGG VDFVGILRAGVADLLHGGARQGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIEKALTKDQILELYMNQIYLGQRAYG FAAAARVYFGKDLKDVTLAEAAMLAGLPKAPSAYNPVVNPKRAKVRQEYILKRMLEIGYITQQQYDQAVKEEIHVRTPGN QYAVHGEYVAEMVRQMMYAQYKDETYTRGLTVTTTINAADQEAAYQAVRRGIMDYERRHGYRGPEGFVALPPAGDERDEA IDDALADHPDNGDLQSAVVLAVSPTAVDVQFVGGATATINGAGLRFAAGALSARASAALKIKPGSIVRVMKDARSAWQIV QLPQVEGALVAVAPQDGAIRSLVGGFDFNKSKFNHVTQAWRQPGSSFKPFIYSASLEKGLGPATIINDAPLYFPPSVPGG QPWEPKDDDQPDGPMPMRTALQRSKNLVSIRILASIGTSYAQDYVTQRFGFDPAKTPPYLPMALGAGLVTPLQLAAGYAV FANGGFKVDPYLIAEVDDARGQALQKAQPVVAGASATRTIDARNAYVMNSLLHTVATAGTGAGTNALGRGDLQGKTGTTN EAKDGWFAGYQQSLVAVAWMGFDQPKSLGSREFGAQLALPIWVNYMRTALNGVPEQQMAMPDGLTTIDGELYYADRTPGA GFVASVDFNPAASPTVSANDALGSAGAAGLTPPPVTPEEKRQIIDMFEGNKP
Sequences:
>Translated_852_residues MLEARLVRRPSDMPIIKRPPSSRATNEHHYSLRRSPAGAYYTDDDDDDERAPRRTGRDGGSRTFGSRVALWFAGLFATLL VVGALIVGYALVVMGPQLPSLDALTNYQPKVPLRVYSADHVLLGEFGEERRSLVRFADIPDVMKKAVLAIEDYRFYEHGG VDFVGILRAGVADLLHGGARQGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIEKALTKDQILELYMNQIYLGQRAYG FAAAARVYFGKDLKDVTLAEAAMLAGLPKAPSAYNPVVNPKRAKVRQEYILKRMLEIGYITQQQYDQAVKEEIHVRTPGN QYAVHGEYVAEMVRQMMYAQYKDETYTRGLTVTTTINAADQEAAYQAVRRGIMDYERRHGYRGPEGFVALPPAGDERDEA IDDALADHPDNGDLQSAVVLAVSPTAVDVQFVGGATATINGAGLRFAAGALSARASAALKIKPGSIVRVMKDARSAWQIV QLPQVEGALVAVAPQDGAIRSLVGGFDFNKSKFNHVTQAWRQPGSSFKPFIYSASLEKGLGPATIINDAPLYFPPSVPGG QPWEPKDDDQPDGPMPMRTALQRSKNLVSIRILASIGTSYAQDYVTQRFGFDPAKTPPYLPMALGAGLVTPLQLAAGYAV FANGGFKVDPYLIAEVDDARGQALQKAQPVVAGASATRTIDARNAYVMNSLLHTVATAGTGAGTNALGRGDLQGKTGTTN EAKDGWFAGYQQSLVAVAWMGFDQPKSLGSREFGAQLALPIWVNYMRTALNGVPEQQMAMPDGLTTIDGELYYADRTPGA GFVASVDFNPAASPTVSANDALGSAGAAGLTPPPVTPEEKRQIIDMFEGNKP >Mature_852_residues MLEARLVRRPSDMPIIKRPPSSRATNEHHYSLRRSPAGAYYTDDDDDDERAPRRTGRDGGSRTFGSRVALWFAGLFATLL VVGALIVGYALVVMGPQLPSLDALTNYQPKVPLRVYSADHVLLGEFGEERRSLVRFADIPDVMKKAVLAIEDYRFYEHGG VDFVGILRAGVADLLHGGARQGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIEKALTKDQILELYMNQIYLGQRAYG FAAAARVYFGKDLKDVTLAEAAMLAGLPKAPSAYNPVVNPKRAKVRQEYILKRMLEIGYITQQQYDQAVKEEIHVRTPGN QYAVHGEYVAEMVRQMMYAQYKDETYTRGLTVTTTINAADQEAAYQAVRRGIMDYERRHGYRGPEGFVALPPAGDERDEA IDDALADHPDNGDLQSAVVLAVSPTAVDVQFVGGATATINGAGLRFAAGALSARASAALKIKPGSIVRVMKDARSAWQIV QLPQVEGALVAVAPQDGAIRSLVGGFDFNKSKFNHVTQAWRQPGSSFKPFIYSASLEKGLGPATIINDAPLYFPPSVPGG QPWEPKDDDQPDGPMPMRTALQRSKNLVSIRILASIGTSYAQDYVTQRFGFDPAKTPPYLPMALGAGLVTPLQLAAGYAV FANGGFKVDPYLIAEVDDARGQALQKAQPVVAGASATRTIDARNAYVMNSLLHTVATAGTGAGTNALGRGDLQGKTGTTN EAKDGWFAGYQQSLVAVAWMGFDQPKSLGSREFGAQLALPIWVNYMRTALNGVPEQQMAMPDGLTTIDGELYYADRTPGA GFVASVDFNPAASPTVSANDALGSAGAAGLTPPPVTPEEKRQIIDMFEGNKP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=814, Percent_Identity=39.6805896805897, Blast_Score=530, Evalue=1e-151, Organism=Escherichia coli, GI1786343, Length=249, Percent_Identity=36.9477911646586, Blast_Score=147, Evalue=3e-36, Organism=Escherichia coli, GI1788867, Length=265, Percent_Identity=31.6981132075472, Blast_Score=113, Evalue=6e-26, Organism=Escherichia coli, GI1789601, Length=172, Percent_Identity=34.3023255813954, Blast_Score=93, Evalue=8e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 92301; Mature: 92301
Theoretical pI: Translated: 7.44; Mature: 7.44
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLEARLVRRPSDMPIIKRPPSSRATNEHHYSLRRSPAGAYYTDDDDDDERAPRRTGRDGG CCCCHHHCCCCCCCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHCCHHCCCCCC SRTFGSRVALWFAGLFATLLVVGALIVGYALVVMGPQLPSLDALTNYQPKVPLRVYSADH CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEECCCE VLLGEFGEERRSLVRFADIPDVMKKAVLAIEDYRFYEHGGVDFVGILRAGVADLLHGGAR EEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC QGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIEKALTKDQILELYMNQIYLGQRAYG CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH FAAAARVYFGKDLKDVTLAEAAMLAGLPKAPSAYNPVVNPKRAKVRQEYILKRMLEIGYI HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH TQQQYDQAVKEEIHVRTPGNQYAVHGEYVAEMVRQMMYAQYKDETYTRGLTVTTTINAAD HHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCH QEAAYQAVRRGIMDYERRHGYRGPEGFVALPPAGDERDEAIDDALADHPDNGDLQSAVVL HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEEE AVSPTAVDVQFVGGATATINGAGLRFAAGALSARASAALKIKPGSIVRVMKDARSAWQIV EECCCEEEEEEECCCEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEE QLPQVEGALVAVAPQDGAIRSLVGGFDFNKSKFNHVTQAWRQPGSSFKPFIYSASLEKGL ECCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCC GPATIINDAPLYFPPSVPGGQPWEPKDDDQPDGPMPMRTALQRSKNLVSIRILASIGTSY CCEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHCHHH AQDYVTQRFGFDPAKTPPYLPMALGAGLVTPLQLAAGYAVFANGGFKVDPYLIAEVDDAR HHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEECCCEEECCEEEEECCCHH GQALQKAQPVVAGASATRTIDARNAYVMNSLLHTVATAGTGAGTNALGRGDLQGKTGTTN HHHHHHCCCCEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC EAKDGWFAGYQQSLVAVAWMGFDQPKSLGSREFGAQLALPIWVNYMRTALNGVPEQQMAM CCCCCHHHHHHHHHHHHHHCCCCCCHHCCCHHHCCEEEHHHHHHHHHHHHCCCCHHHHCC PDGLTTIDGELYYADRTPGAGFVASVDFNPAASPTVSANDALGSAGAAGLTPPPVTPEEK CCCCEEECCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH RQIIDMFEGNKP HHHHHHHCCCCC >Mature Secondary Structure MLEARLVRRPSDMPIIKRPPSSRATNEHHYSLRRSPAGAYYTDDDDDDERAPRRTGRDGG CCCCHHHCCCCCCCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHCCHHCCCCCC SRTFGSRVALWFAGLFATLLVVGALIVGYALVVMGPQLPSLDALTNYQPKVPLRVYSADH CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEECCCE VLLGEFGEERRSLVRFADIPDVMKKAVLAIEDYRFYEHGGVDFVGILRAGVADLLHGGAR EEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC QGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIEKALTKDQILELYMNQIYLGQRAYG CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH FAAAARVYFGKDLKDVTLAEAAMLAGLPKAPSAYNPVVNPKRAKVRQEYILKRMLEIGYI HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH TQQQYDQAVKEEIHVRTPGNQYAVHGEYVAEMVRQMMYAQYKDETYTRGLTVTTTINAAD HHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCH QEAAYQAVRRGIMDYERRHGYRGPEGFVALPPAGDERDEAIDDALADHPDNGDLQSAVVL HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEEE AVSPTAVDVQFVGGATATINGAGLRFAAGALSARASAALKIKPGSIVRVMKDARSAWQIV EECCCEEEEEEECCCEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEE QLPQVEGALVAVAPQDGAIRSLVGGFDFNKSKFNHVTQAWRQPGSSFKPFIYSASLEKGL ECCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCC GPATIINDAPLYFPPSVPGGQPWEPKDDDQPDGPMPMRTALQRSKNLVSIRILASIGTSY CCEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHCHHH AQDYVTQRFGFDPAKTPPYLPMALGAGLVTPLQLAAGYAVFANGGFKVDPYLIAEVDDAR HHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEECCCEEECCEEEEECCCHH GQALQKAQPVVAGASATRTIDARNAYVMNSLLHTVATAGTGAGTNALGRGDLQGKTGTTN HHHHHHCCCCEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC EAKDGWFAGYQQSLVAVAWMGFDQPKSLGSREFGAQLALPIWVNYMRTALNGVPEQQMAM CCCCCHHHHHHHHHHHHHHCCCCCCHHCCCHHHCCEEEHHHHHHHHHHHHCCCCHHHHCC PDGLTTIDGELYYADRTPGAGFVASVDFNPAASPTVSANDALGSAGAAGLTPPPVTPEEK CCCCEEECCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH RQIIDMFEGNKP HHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA