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The map label for this gene is yycG [H]

Identifier: 53719595

GI number: 53719595

Start: 2364186

End: 2366579

Strand: Reverse

Name: yycG [H]

Synonym: BPSL1983

Alternate gene names: 53719595

Gene position: 2366579-2364186 (Counterclockwise)

Preceding gene: 53719596

Following gene: 53719594

Centisome position: 58.08

GC content: 69.26

Gene sequence:

>2394_bases
ATGAGATTCGACCGCACGCAACGGCGGCGGCTGCTCGGCCGCCGTTTTCTCGTCGAGTGGATCGCGATCGGCTGCCTCGG
GGTCGCGGTGATTCTCGCCGGCGTCGCCGGCCGGATGACGGCGAGCGTCGACCGGATCATCTACGATCGCCTGCTCACGC
TGCGCAAGCTGCCGATCGAGTCGAACATCGTGATCGTCGAGATCGACAATCGCAGCCTCGACACGCTCGGGCGCTGGCCA
TGGCAGCGCAGCGTCCATGCGGAATTCCTCGGCGCGCTCGCGAAGACGCATCCGGCGGCCGTCGTCTACGACGTGCTGTT
TACCGAGCCGTCCGCCGACGACCGCGCGCTCGCGAAGGTGCTCGATCTCGTGCCGACGTTCCTGCCCGTGCTGCTGAGCC
CGGAGGAGCCCGACGGCACGCGCACCGTCAATCCGCCCGTGCCGGTGCTCGCGCAGCACGTCGCGGGCGCGGGCCACATC
AATCTCGAAGTCGATCCGGACGGCATCGTGCGCAGCGTCGCGCTGTTCGAGAGCGACGGGCTGCACCGCTGGCCGCAGTT
GATGGTGCCCGTGTTCCACGCGCTCGAGAACGGCCAGTTCAAGCTCGCGCAGCCCGCGCCGATCGCGCGGCGCGCGCACG
ACATCGCGCAGGACGACAACGGCGAGTCGCGCTATTTCGTCCCGTTCAGCCGCGCGTCGCAGAACTACCCGGCGATTTCG
TTCGTCGACGTGCTCGCGGGCCGCGTGAACGCCGACGAGCTGCGCGGCAAGATCGTGATCGTCGGCGCGACCGCGTCGGG
CCTCTACGACCGCTTCGCGACGCCGATCTCGGGCGAGTTCGGGCCGCTGCCGGGCGTGTACATCCATGCGAGTGTGCTCG
ATACGCTGATGACGGGCCGCGCGATCTCGCCCGTGTCCGGCTGGCTCGTGTTCAGCGCGTCGCTGCTGCCGCTCGTCGTG
CTGCTCGCGGGCTTCCTGATGCTCTCGCCGTGGCGCTCGCTGCTCCTCACGCTGAGCCTTGCCGCGCTCGCGGTCGCCTC
GAGCGCGGCGCTCCTCTACGAGGCGCGGCTGTGGCTGTCGCCCGCGCCGGCGATCTTCGGGCTGATCGCCGCGTACCCGA
TCTGGAACTGGCGGCGCCTCGAGATGACGATGTCGTACCTGCGCTACGAGCTGCAGCGCCTCGCCGACGAGCCGCACCTG
CTGCCCGAGGCGCCGCGCGAGCGCAACGAATTCGGCGGCGACGTGCTCGAGCGTCAGATGGCGCTGATGGCGCAGGCCGC
GCAGCGCGTGCAGGACATGAAGCGCTTCGTCTGGGACAGCCTCGACAGCATGCCGGAGCCCGTCGTCGTGACCGATCTCG
CGGGCACGGTGCTGATCGCCAATCATGCGGCGAAGCGCTACTGCGCGCGGCTAGACGCTCCCGCGCCGGAAGGGCGGCCG
CTGCGCGTCGCGTTCGGCGAGCTGTCGTTCGTGAAGACGGTCGACGGCAACGCCGAGCAGGACGTCGCGATCCGCACGCA
CTGGCCGGCCGCGCTCGACCCGACGCGCGACTACGAGAACGACGTGATGGAGCGCGGCATCGAGGTGCGCGACCGCAGCG
GCCTCGATCATCTGCTACGCTACGCGCCGTGCACGAACGCGCAGGGCAACGTGACGGGCTGGATCGCCGGCCTCGTCGAC
GTGACCGCGCTGCATGCGGCCGAGCGGCAGCGCGAGGAGGCGCTGCATCTGCTGTCGCACGACATGCGCTCGCCGCAATC
GTCGATTCTCGCGCTCGTCGAGATCGAGCGGCAGCGGGCCGAATCCGAGCACACGCGCGGGCTGCTCGCGCGCATCGAGC
GCTACGCGCAGCGTGCGCTGATGCTCGCCGACGAGTTCGTGCAGCTCGCGCGCGCGGAATCGCAGACGTACCAGCTCGAG
GCGGTGAGCTTCGCCGATTTGCTGATCGACGCGAGCGACGAAGTGTGGCCGCAGGCGCAGGCCAAGCGCATCCGCATCGA
CACGTCGTTCGGCGACGAGCCGTGCTGGATCGGCGCCGACCGCTCGCTGATGACCCGCGCGCTCGTGAATCTGTTGAACA
ATGCGGTCAAATACAGCCCGACGGACACGGTGATCACGTGTACGCTATCAGTCGAGCCGGGCGCGAAGCGCGTACATTGC
ACGATCCGCGACCAGGGCTACGGCATTTCGCTCGAGGATCAGCGGCATCTGTTCGAGCGTTTCAAGCGGTTTCATGCGAA
CGAGCGGCCGGAGGTCGCGGGCTCCGGGCTCGGCATGGCGTTCGTCAAGACCGTGGTCGTGCGGCACGGCGGTTGCATCG
GCGTCGACAGTACGCCGGGCATCGGCACGGCGATCACCGTGTCGCTGCCGTTGCTCGACGAGCCGGCGGCGTGA

Upstream 100 bases:

>100_bases
TACTACTGGAGCGTGATCGCGGAGCGCTACGAAGGCGGCCGTTTCCACGAAAAGGCCAGCGCGGTCAACGCGTTCACGAT
CGCGCGCTGATGGGCGGCGG

Downstream 100 bases:

>100_bases
CGACACAGGCATTCGGCCGCCCGCGCGAGTGGGGCTCGCGCACGGGCGGATGGCTAGGACGGGGGCGAACAGCGATATGG
GAGAAGCTATGAAAGTCTTG

Product: putative two component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MRFDRTQRRRLLGRRFLVEWIAIGCLGVAVILAGVAGRMTASVDRIIYDRLLTLRKLPIESNIVIVEIDNRSLDTLGRWP
WQRSVHAEFLGALAKTHPAAVVYDVLFTEPSADDRALAKVLDLVPTFLPVLLSPEEPDGTRTVNPPVPVLAQHVAGAGHI
NLEVDPDGIVRSVALFESDGLHRWPQLMVPVFHALENGQFKLAQPAPIARRAHDIAQDDNGESRYFVPFSRASQNYPAIS
FVDVLAGRVNADELRGKIVIVGATASGLYDRFATPISGEFGPLPGVYIHASVLDTLMTGRAISPVSGWLVFSASLLPLVV
LLAGFLMLSPWRSLLLTLSLAALAVASSAALLYEARLWLSPAPAIFGLIAAYPIWNWRRLEMTMSYLRYELQRLADEPHL
LPEAPRERNEFGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPVVVTDLAGTVLIANHAAKRYCARLDAPAPEGRP
LRVAFGELSFVKTVDGNAEQDVAIRTHWPAALDPTRDYENDVMERGIEVRDRSGLDHLLRYAPCTNAQGNVTGWIAGLVD
VTALHAAERQREEALHLLSHDMRSPQSSILALVEIERQRAESEHTRGLLARIERYAQRALMLADEFVQLARAESQTYQLE
AVSFADLLIDASDEVWPQAQAKRIRIDTSFGDEPCWIGADRSLMTRALVNLLNNAVKYSPTDTVITCTLSVEPGAKRVHC
TIRDQGYGISLEDQRHLFERFKRFHANERPEVAGSGLGMAFVKTVVVRHGGCIGVDSTPGIGTAITVSLPLLDEPAA

Sequences:

>Translated_797_residues
MRFDRTQRRRLLGRRFLVEWIAIGCLGVAVILAGVAGRMTASVDRIIYDRLLTLRKLPIESNIVIVEIDNRSLDTLGRWP
WQRSVHAEFLGALAKTHPAAVVYDVLFTEPSADDRALAKVLDLVPTFLPVLLSPEEPDGTRTVNPPVPVLAQHVAGAGHI
NLEVDPDGIVRSVALFESDGLHRWPQLMVPVFHALENGQFKLAQPAPIARRAHDIAQDDNGESRYFVPFSRASQNYPAIS
FVDVLAGRVNADELRGKIVIVGATASGLYDRFATPISGEFGPLPGVYIHASVLDTLMTGRAISPVSGWLVFSASLLPLVV
LLAGFLMLSPWRSLLLTLSLAALAVASSAALLYEARLWLSPAPAIFGLIAAYPIWNWRRLEMTMSYLRYELQRLADEPHL
LPEAPRERNEFGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPVVVTDLAGTVLIANHAAKRYCARLDAPAPEGRP
LRVAFGELSFVKTVDGNAEQDVAIRTHWPAALDPTRDYENDVMERGIEVRDRSGLDHLLRYAPCTNAQGNVTGWIAGLVD
VTALHAAERQREEALHLLSHDMRSPQSSILALVEIERQRAESEHTRGLLARIERYAQRALMLADEFVQLARAESQTYQLE
AVSFADLLIDASDEVWPQAQAKRIRIDTSFGDEPCWIGADRSLMTRALVNLLNNAVKYSPTDTVITCTLSVEPGAKRVHC
TIRDQGYGISLEDQRHLFERFKRFHANERPEVAGSGLGMAFVKTVVVRHGGCIGVDSTPGIGTAITVSLPLLDEPAA
>Mature_797_residues
MRFDRTQRRRLLGRRFLVEWIAIGCLGVAVILAGVAGRMTASVDRIIYDRLLTLRKLPIESNIVIVEIDNRSLDTLGRWP
WQRSVHAEFLGALAKTHPAAVVYDVLFTEPSADDRALAKVLDLVPTFLPVLLSPEEPDGTRTVNPPVPVLAQHVAGAGHI
NLEVDPDGIVRSVALFESDGLHRWPQLMVPVFHALENGQFKLAQPAPIARRAHDIAQDDNGESRYFVPFSRASQNYPAIS
FVDVLAGRVNADELRGKIVIVGATASGLYDRFATPISGEFGPLPGVYIHASVLDTLMTGRAISPVSGWLVFSASLLPLVV
LLAGFLMLSPWRSLLLTLSLAALAVASSAALLYEARLWLSPAPAIFGLIAAYPIWNWRRLEMTMSYLRYELQRLADEPHL
LPEAPRERNEFGGDVLERQMALMAQAAQRVQDMKRFVWDSLDSMPEPVVVTDLAGTVLIANHAAKRYCARLDAPAPEGRP
LRVAFGELSFVKTVDGNAEQDVAIRTHWPAALDPTRDYENDVMERGIEVRDRSGLDHLLRYAPCTNAQGNVTGWIAGLVD
VTALHAAERQREEALHLLSHDMRSPQSSILALVEIERQRAESEHTRGLLARIERYAQRALMLADEFVQLARAESQTYQLE
AVSFADLLIDASDEVWPQAQAKRIRIDTSFGDEPCWIGADRSLMTRALVNLLNNAVKYSPTDTVITCTLSVEPGAKRVHC
TIRDQGYGISLEDQRHLFERFKRFHANERPEVAGSGLGMAFVKTVVVRHGGCIGVDSTPGIGTAITVSLPLLDEPAA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=370, Percent_Identity=26.2162162162162, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=28.5067873303167, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788549, Length=428, Percent_Identity=23.8317757009346, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=26.6094420600858, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=28.6919831223629, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=22.8448275862069, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=30.1724137931034, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=24.4444444444444, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=196, Percent_Identity=30.6122448979592, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=267, Percent_Identity=24.3445692883895, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88007; Mature: 88007

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDRTQRRRLLGRRFLVEWIAIGCLGVAVILAGVAGRMTASVDRIIYDRLLTLRKLPIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SNIVIVEIDNRSLDTLGRWPWQRSVHAEFLGALAKTHPAAVVYDVLFTEPSADDRALAKV
CCEEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHEEHHHCCCCCCCHHHHHHH
LDLVPTFLPVLLSPEEPDGTRTVNPPVPVLAQHVAGAGHINLEVDPDGIVRSVALFESDG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCC
LHRWPQLMVPVFHALENGQFKLAQPAPIARRAHDIAQDDNGESRYFVPFSRASQNYPAIS
CHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCHH
FVDVLAGRVNADELRGKIVIVGATASGLYDRFATPISGEFGPLPGVYIHASVLDTLMTGR
HHHHHHCCCCHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHCCC
AISPVSGWLVFSASLLPLVVLLAGFLMLSPWRSLLLTLSLAALAVASSAALLYEARLWLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAPAIFGLIAAYPIWNWRRLEMTMSYLRYELQRLADEPHLLPEAPRERNEFGGDVLERQM
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHH
ALMAQAAQRVQDMKRFVWDSLDSMPEPVVVTDLAGTVLIANHAAKRYCARLDAPAPEGRP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCE
LRVAFGELSFVKTVDGNAEQDVAIRTHWPAALDPTRDYENDVMERGIEVRDRSGLDHLLR
EEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHH
YAPCTNAQGNVTGWIAGLVDVTALHAAERQREEALHLLSHDMRSPQSSILALVEIERQRA
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ESEHTRGLLARIERYAQRALMLADEFVQLARAESQTYQLEAVSFADLLIDASDEVWPQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCC
AKRIRIDTSFGDEPCWIGADRSLMTRALVNLLNNAVKYSPTDTVITCTLSVEPGAKRVHC
CCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEE
TIRDQGYGISLEDQRHLFERFKRFHANERPEVAGSGLGMAFVKTVVVRHGGCIGVDSTPG
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCC
IGTAITVSLPLLDEPAA
CCEEEEEEEECCCCCCC
>Mature Secondary Structure
MRFDRTQRRRLLGRRFLVEWIAIGCLGVAVILAGVAGRMTASVDRIIYDRLLTLRKLPIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SNIVIVEIDNRSLDTLGRWPWQRSVHAEFLGALAKTHPAAVVYDVLFTEPSADDRALAKV
CCEEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHEEHHHCCCCCCCHHHHHHH
LDLVPTFLPVLLSPEEPDGTRTVNPPVPVLAQHVAGAGHINLEVDPDGIVRSVALFESDG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCC
LHRWPQLMVPVFHALENGQFKLAQPAPIARRAHDIAQDDNGESRYFVPFSRASQNYPAIS
CHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCHH
FVDVLAGRVNADELRGKIVIVGATASGLYDRFATPISGEFGPLPGVYIHASVLDTLMTGR
HHHHHHCCCCHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHCCC
AISPVSGWLVFSASLLPLVVLLAGFLMLSPWRSLLLTLSLAALAVASSAALLYEARLWLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAPAIFGLIAAYPIWNWRRLEMTMSYLRYELQRLADEPHLLPEAPRERNEFGGDVLERQM
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHH
ALMAQAAQRVQDMKRFVWDSLDSMPEPVVVTDLAGTVLIANHAAKRYCARLDAPAPEGRP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCE
LRVAFGELSFVKTVDGNAEQDVAIRTHWPAALDPTRDYENDVMERGIEVRDRSGLDHLLR
EEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHH
YAPCTNAQGNVTGWIAGLVDVTALHAAERQREEALHLLSHDMRSPQSSILALVEIERQRA
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ESEHTRGLLARIERYAQRALMLADEFVQLARAESQTYQLEAVSFADLLIDASDEVWPQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCC
AKRIRIDTSFGDEPCWIGADRSLMTRALVNLLNNAVKYSPTDTVITCTLSVEPGAKRVHC
CCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEE
TIRDQGYGISLEDQRHLFERFKRFHANERPEVAGSGLGMAFVKTVVVRHGGCIGVDSTPG
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCC
IGTAITVSLPLLDEPAA
CCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]