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The map label for this gene is yafC [H]

Identifier: 53719562

GI number: 53719562

Start: 2322043

End: 2322948

Strand: Reverse

Name: yafC [H]

Synonym: BPSL1950

Alternate gene names: 53719562

Gene position: 2322948-2322043 (Counterclockwise)

Preceding gene: 53719566

Following gene: 53719561

Centisome position: 57.01

GC content: 72.08

Gene sequence:

>906_bases
ATGCTGATCGACGATCTGCCGGCGCTCGCGACATTCGCGCGGATCGTCGCGGCGGGCAGTCTGTCAGCCGCGGCGCGTGA
GCTCGATCTGTCGCTGTCGGTGGTCAGCAAGCGGCTCGCGCAGCTCGAAACGCGGCTGGGCGTGCGGCTGTTGCAGCGGA
CGACGCGTCAGCAGACACTGACCGACGAGGGCGCGCTGTTCCACGCGCAAGTCGTGAGGATCCTCGCGGAGATCGAGCAG
GCCGAATCGCTGATGCGCGAGCGCCGCGGCACCGTGAGCGGCGCGCTGCGGATCACGGCGCCCGGCGAGCTCGGGCGGCG
GCGGATCGCGCCCATCGTCGCCGCGTTCCAGCGGCAGCATCCGCAGGTGACGGTGCAGATGCAGCTCACCGATGCCGTCG
TCGACCTCATCGCGCACGACGTCGACGTCGCGGTGCGGATCGGCATGCTCGCGGATTCGTCGCTGATCGCGCGCGAGCTC
GCGCCGAACTACCGCGTGCTGTGTGCGTCGCCTGCGTATCTCGCCGAGCACGGCATGCCCGCGCAGCCCGCCGATCTGTG
CGCGCACCGGTGCATCGTGCTGGGCGAGCAGCCGCGCGTCGAATGGCGCTTCGACGGGTCGCATCCCGCGGCGGTCGAGG
TGTCGGCCGCGTTCCTGACGAACGACGGCGGCGCGGCCCGCACGCTCGCGCTGGAAGGCGCGGGCATCGCGCTGAAATCG
ATCTGGGACGTGGGGCCGGACCTTGCCGCGGGGCGGCTGCGGCGCGTGCTGCCCGAATGCGCGTCGAGCGCCGCGCCGTT
GCACGCGGTCTATCCGAGCGGCCGGCATCTCGCGCTGCGCGTGCGGACGTTCGTCGACTATCTCGGCGTCGAGCTGCGCC
GCGCGTGGCGCTGGGACGAGCGATGA

Upstream 100 bases:

>100_bases
ATTCATGTTAGTTTTCCGATTTCGATATAAATACGGGCCAAGAGCGAATGAATTCTTCGCAAAAAGGAAAGATTGCGCGG
GGCCGTCGGCGAGGCGGCCG

Downstream 100 bases:

>100_bases
CGTGCGGCGGCCGGCGCGCGGCCGCATGGCGGCGGGGCCCGGCGATCAGGCGGCCGGCGATCGGACGGCCGCGTTTCGCA
TGCGCGGCCGCTTCTCCGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGVRLLQRTTRQQTLTDEGALFHAQVVRILAEIEQ
AESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQLTDAVVDLIAHDVDVAVRIGMLADSSLIAREL
APNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGSHPAAVEVSAAFLTNDGGAARTLALEGAGIALKS
IWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYLGVELRRAWRWDER

Sequences:

>Translated_301_residues
MLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGVRLLQRTTRQQTLTDEGALFHAQVVRILAEIEQ
AESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQLTDAVVDLIAHDVDVAVRIGMLADSSLIAREL
APNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGSHPAAVEVSAAFLTNDGGAARTLALEGAGIALKS
IWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYLGVELRRAWRWDER
>Mature_301_residues
MLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGVRLLQRTTRQQTLTDEGALFHAQVVRILAEIEQ
AESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQHPQVTVQMQLTDAVVDLIAHDVDVAVRIGMLADSSLIAREL
APNYRVLCASPAYLAEHGMPAQPADLCAHRCIVLGEQPRVEWRFDGSHPAAVEVSAAFLTNDGGAARTLALEGAGIALKS
IWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYLGVELRRAWRWDER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=37.2013651877133, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=37.6712328767123, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=33.5689045936396, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=31.3793103448276, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=29.0657439446367, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=31.986531986532, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=26.027397260274, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787601, Length=138, Percent_Identity=29.7101449275362, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=24.7386759581882, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788706, Length=263, Percent_Identity=26.2357414448669, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=293, Percent_Identity=27.3037542662116, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=141, Percent_Identity=31.9148936170213, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32759; Mature: 32759

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGVRLLQRTTRQQTL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDEGALFHAQVVRILAEIEQAESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCC
PQVTVQMQLTDAVVDLIAHDVDVAVRIGMLADSSLIARELAPNYRVLCASPAYLAEHGMP
CCEEEEEEHHHHHHHHHHHCHHHHHEEEHHCCHHHHHHHHCCCCEEEECCCHHHHHCCCC
AQPADLCAHRCIVLGEQPRVEWRFDGSHPAAVEVSAAFLTNDGGAARTLALEGAGIALKS
CCHHHHHHHHHEEECCCCCEEEEECCCCCCEEEEEEEEEECCCCCEEEEEECCCCCHHHH
IWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYLGVELRRAWRWDE
HHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
R
C
>Mature Secondary Structure
MLIDDLPALATFARIVAAGSLSAAARELDLSLSVVSKRLAQLETRLGVRLLQRTTRQQTL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDEGALFHAQVVRILAEIEQAESLMRERRGTVSGALRITAPGELGRRRIAPIVAAFQRQH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCC
PQVTVQMQLTDAVVDLIAHDVDVAVRIGMLADSSLIARELAPNYRVLCASPAYLAEHGMP
CCEEEEEEHHHHHHHHHHHCHHHHHEEEHHCCHHHHHHHHCCCCEEEECCCHHHHHCCCC
AQPADLCAHRCIVLGEQPRVEWRFDGSHPAAVEVSAAFLTNDGGAARTLALEGAGIALKS
CCHHHHHHHHHEEECCCCCEEEEECCCCCCEEEEEEEEEECCCCCEEEEEECCCCCHHHH
IWDVGPDLAAGRLRRVLPECASSAAPLHAVYPSGRHLALRVRTFVDYLGVELRRAWRWDE
HHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]