| Definition | Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_006350 |
| Length | 4,074,542 |
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The map label for this gene is relA [H]
Identifier: 53719559
GI number: 53719559
Start: 2317104
End: 2319341
Strand: Reverse
Name: relA [H]
Synonym: BPSL1946
Alternate gene names: 53719559
Gene position: 2319341-2317104 (Counterclockwise)
Preceding gene: 53719560
Following gene: 53719558
Centisome position: 56.92
GC content: 68.72
Gene sequence:
>2238_bases ATGACAGCCGATTCCGCTTCCACCGCCGCGGCGCCGTCGCTCGACGACGTGCTCGCGTTCGTGCGCGAGCACGCGGGCGA CGCGCGCTTGTCGTCGGGAGAGCGGCTCGCCGATCATGCGGCGGGCACGTCGACGATCATGCAGCGGCTGAACGTCGATC CGCCCGCGACGCAGGCGGCCGCGCTGTTCGCGCTCGCGCCGTATCTGAGCGATCCTGACAAGCAGATCGCCGAGCACTTC GGCGACGAGGTCGCGCACCTCGTCGCCGACGTGCGCAAGCTGCTGCGCCTCGGTACCGTGAGCCTGCGCGCTGCGCAGAG CGCGCCTGTCGATGCGGGCCGCGACGCACAGGCGGAGCGCCGCGCGCAGATCGAAGCGCTGCGCAAGATGCTGCTCGCGT TCGCGCAGGACATCCGCGTCGTGCTGATCCGGCTCGCGTCGCGGCTGCAATCGTTGCGCTACTATGCGGCCGCGAAAATC GAGCCGCCGCCCGACGTCGCGCGCGAGACGCTCGAAATCTACGCGCCGCTCGCGAACCGGCTCGGCATCTGGCAACTGAA GTGGGAGCTCGAGGATCTCGCGTTCCGCTTCGAGGATCCCGTCACCTACAAGCGCATCGCGAAGCTGCTCGACGAGAAGC GCGTCGAGCGCGAGGCGTACGTCGCCGGCGCGATCGAGCGGTTGCAGCACGAACTGGCGGCCGCGCACATCCAGGCCGAA GTGAGCGGCCGGCCGAAGCACATCTACAGCATCTGGCGCAAGATGCGCGGCAAGGAGCTCGACTTCTCCGAGCTCTACGA CGTGCGCGCGTTTCGCGTCATCGTGCCGGACATCAAGGATTGCTACACGGTGCTCGGCATCGTCCACCACCTGTGGCAGC CGGTGCCGAAGGAATTCGACGATTACATCTCGCGGCCGAAGCCGAACGGCTACAAATCGCTGCATACGGTCGTGATCGGC GACGACGGTCGCGCGTTCGAAGTGCAGATCCGCACGCAGGAAATGCACCGCTTCGCCGAGTACGGCGTCGCCGCGCACTG GCGGTACAAGGAGGCGGGCGCGCGCGGCTACGGCGGCCAGTTCTCCGCGAGCGAGAAATACGACGAGAAGATCGCGTGGC TGCGCCAACTGCTCGCGTGGAAGGACGAGATCGCGGACGGCGGCGGCGCGGAGGTGAGCGGTCAGCAGGCATGGGCGCAA CTGCGCGAGGCGACGCTCGACGACGACCACATTTACGTGCTGACGCCGCAGGCGCGCGTGATCGCGCTGCCGCAGGGCGC GACGCCCGTCGATTTCGCTTACCACCTGCACAGCGAACTGGGGCACCGTTGCCGCGGCGCGCGTGTCGACGGCGCGATGG TGCCGCTCAACACGCAGCTCGCGAACGGCCAGACGGTCGAGATCGTCGCGGTGAAGGAGGGCGGCCCGTCGCGCGACTGG CTCAACCCGCAGCTCGGCTATCTGCACAGCTCACGGGCGCGCCAGAAGGTGCGCGCATGGTTCAACGCGGTCGATCAGCA GGAGAACGTCGCGCACGGCCGCGCGCTCGTCGAAAAGACGCTGCAGCGCGAAGGCAAGACGTCGGTGAATCTCGAGCATC TCGCGGCGAAGCTCGGCTTCAAGTCGCCGGACGAACTGTTTTCGGTCGTCGGCAAGGAAGAGTTCAGCCTGCGCAACGTC GAGCAGGCGCTGTCCGATGCGCCGGCGCCCGAACCCGAGCCGGAGGCGCCCGCGAACTTCGAGAAGCGCGCGAGCGGCGC GAACGTCGCGCACGGCGCGTCGGCGGGGGTGCTCGTCGTCGGCGTCGACGCGCTTCTCACCCAGCTCGCCCGCTGCTGCC GGCCGGCGCCGCCCGATCCGATCAGCGGCTTCGTCACGCGCGGCAAGGGGATGTCGATCCATCGCAGCGATTGCGCGACC TTCCGCCGGATGGCCGAGCGCGCGCCCGAGCGCGTGCTGCAGACCACCTGGTCCGCCGACGTGCTGGGCGGGCGGGGCGC GTCCGTCTACCCGGTCGACCTGATGATCGAGGCGACCGACCGGCAAGGGCTGTTGCGCGACATCTCCGAAGTGTTTGCGC GCGAGAAGATGAACGTGATCGGCGTGAAGACGCAAAGTCGCCGCAACGCGGCCTTCATGCAATTCACGGTCGAGGTGTCG AGTGCGTCGCAGGTGCAGCGCGCGTGCACGCTGCTTGGCGAGATTCAGGGCGTCGTTCGGGCGGCCCGCAAGGCGTGA
Upstream 100 bases:
>100_bases TCGCGAACCCCGCTTGCCTGGTCGAGGTGGTGGTGGTCGCCGCGCAACGCGGCTGAGCCGGCGCGCGCACGTTTTTTCAG GCAACTGGCCATACCCGACG
Downstream 100 bases:
>100_bases GCGCCGCCGGTGGGCCGCGGCGCGGCAACGGCTTGCGAATTTTCCCGAACGAAATGCACGAAACCACTTGCCAAGGCGAA AAGAGCTCCATATAATTTCA
Product: GTP pyrophosphokinase
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 745; Mature: 744
Protein sequence:
>745_residues MTADSASTAAAPSLDDVLAFVREHAGDARLSSGERLADHAAGTSTIMQRLNVDPPATQAAALFALAPYLSDPDKQIAEHF GDEVAHLVADVRKLLRLGTVSLRAAQSAPVDAGRDAQAERRAQIEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKI EPPPDVARETLEIYAPLANRLGIWQLKWELEDLAFRFEDPVTYKRIAKLLDEKRVEREAYVAGAIERLQHELAAAHIQAE VSGRPKHIYSIWRKMRGKELDFSELYDVRAFRVIVPDIKDCYTVLGIVHHLWQPVPKEFDDYISRPKPNGYKSLHTVVIG DDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGARGYGGQFSASEKYDEKIAWLRQLLAWKDEIADGGGAEVSGQQAWAQ LREATLDDDHIYVLTPQARVIALPQGATPVDFAYHLHSELGHRCRGARVDGAMVPLNTQLANGQTVEIVAVKEGGPSRDW LNPQLGYLHSSRARQKVRAWFNAVDQQENVAHGRALVEKTLQREGKTSVNLEHLAAKLGFKSPDELFSVVGKEEFSLRNV EQALSDAPAPEPEPEAPANFEKRASGANVAHGASAGVLVVGVDALLTQLARCCRPAPPDPISGFVTRGKGMSIHRSDCAT FRRMAERAPERVLQTTWSADVLGGRGASVYPVDLMIEATDRQGLLRDISEVFAREKMNVIGVKTQSRRNAAFMQFTVEVS SASQVQRACTLLGEIQGVVRAARKA
Sequences:
>Translated_745_residues MTADSASTAAAPSLDDVLAFVREHAGDARLSSGERLADHAAGTSTIMQRLNVDPPATQAAALFALAPYLSDPDKQIAEHF GDEVAHLVADVRKLLRLGTVSLRAAQSAPVDAGRDAQAERRAQIEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKI EPPPDVARETLEIYAPLANRLGIWQLKWELEDLAFRFEDPVTYKRIAKLLDEKRVEREAYVAGAIERLQHELAAAHIQAE VSGRPKHIYSIWRKMRGKELDFSELYDVRAFRVIVPDIKDCYTVLGIVHHLWQPVPKEFDDYISRPKPNGYKSLHTVVIG DDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGARGYGGQFSASEKYDEKIAWLRQLLAWKDEIADGGGAEVSGQQAWAQ LREATLDDDHIYVLTPQARVIALPQGATPVDFAYHLHSELGHRCRGARVDGAMVPLNTQLANGQTVEIVAVKEGGPSRDW LNPQLGYLHSSRARQKVRAWFNAVDQQENVAHGRALVEKTLQREGKTSVNLEHLAAKLGFKSPDELFSVVGKEEFSLRNV EQALSDAPAPEPEPEAPANFEKRASGANVAHGASAGVLVVGVDALLTQLARCCRPAPPDPISGFVTRGKGMSIHRSDCAT FRRMAERAPERVLQTTWSADVLGGRGASVYPVDLMIEATDRQGLLRDISEVFAREKMNVIGVKTQSRRNAAFMQFTVEVS SASQVQRACTLLGEIQGVVRAARKA >Mature_744_residues TADSASTAAAPSLDDVLAFVREHAGDARLSSGERLADHAAGTSTIMQRLNVDPPATQAAALFALAPYLSDPDKQIAEHFG DEVAHLVADVRKLLRLGTVSLRAAQSAPVDAGRDAQAERRAQIEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKIE PPPDVARETLEIYAPLANRLGIWQLKWELEDLAFRFEDPVTYKRIAKLLDEKRVEREAYVAGAIERLQHELAAAHIQAEV SGRPKHIYSIWRKMRGKELDFSELYDVRAFRVIVPDIKDCYTVLGIVHHLWQPVPKEFDDYISRPKPNGYKSLHTVVIGD DGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGARGYGGQFSASEKYDEKIAWLRQLLAWKDEIADGGGAEVSGQQAWAQL REATLDDDHIYVLTPQARVIALPQGATPVDFAYHLHSELGHRCRGARVDGAMVPLNTQLANGQTVEIVAVKEGGPSRDWL NPQLGYLHSSRARQKVRAWFNAVDQQENVAHGRALVEKTLQREGKTSVNLEHLAAKLGFKSPDELFSVVGKEEFSLRNVE QALSDAPAPEPEPEAPANFEKRASGANVAHGASAGVLVVGVDALLTQLARCCRPAPPDPISGFVTRGKGMSIHRSDCATF RRMAERAPERVLQTTWSADVLGGRGASVYPVDLMIEATDRQGLLRDISEVFAREKMNVIGVKTQSRRNAAFMQFTVEVSS ASQVQRACTLLGEIQGVVRAARKA
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ACT domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=705, Percent_Identity=40.8510638297872, Blast_Score=542, Evalue=1e-155, Organism=Escherichia coli, GI1790082, Length=700, Percent_Identity=34.5714285714286, Blast_Score=377, Evalue=1e-105,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 82346; Mature: 82215
Theoretical pI: Translated: 7.55; Mature: 7.55
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTADSASTAAAPSLDDVLAFVREHAGDARLSSGERLADHAAGTSTIMQRLNVDPPATQAA CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHH ALFALAPYLSDPDKQIAEHFGDEVAHLVADVRKLLRLGTVSLRAAQSAPVDAGRDAQAER HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH RAQIEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKIEPPPDVARETLEIYAPLANR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC LGIWQLKWELEDLAFRFEDPVTYKRIAKLLDEKRVEREAYVAGAIERLQHELAAAHIQAE CCEEEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VSGRPKHIYSIWRKMRGKELDFSELYDVRAFRVIVPDIKDCYTVLGIVHHLWQPVPKEFD CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHH DYISRPKPNGYKSLHTVVIGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGARGYGGQ HHHCCCCCCCCCCEEEEEECCCCCEEEEEEEHHHHHHHHHCCCHHEEEEHHCCCCCCCCC FSASEKYDEKIAWLRQLLAWKDEIADGGGAEVSGQQAWAQLREATLDDDHIYVLTPQARV CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEE IALPQGATPVDFAYHLHSELGHRCRGARVDGAMVPLNTQLANGQTVEIVAVKEGGPSRDW EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCEEEEEEEECCCCCCCC LNPQLGYLHSSRARQKVRAWFNAVDQQENVAHGRALVEKTLQREGKTSVNLEHLAAKLGF CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC KSPDELFSVVGKEEFSLRNVEQALSDAPAPEPEPEAPANFEKRASGANVAHGASAGVLVV CCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEE GVDALLTQLARCCRPAPPDPISGFVTRGKGMSIHRSDCATFRRMAERAPERVLQTTWSAD EHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC VLGGRGASVYPVDLMIEATDRQGLLRDISEVFAREKMNVIGVKTQSRRNAAFMQFTVEVS CCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECC SASQVQRACTLLGEIQGVVRAARKA CHHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure TADSASTAAAPSLDDVLAFVREHAGDARLSSGERLADHAAGTSTIMQRLNVDPPATQAA CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHH ALFALAPYLSDPDKQIAEHFGDEVAHLVADVRKLLRLGTVSLRAAQSAPVDAGRDAQAER HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH RAQIEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKIEPPPDVARETLEIYAPLANR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC LGIWQLKWELEDLAFRFEDPVTYKRIAKLLDEKRVEREAYVAGAIERLQHELAAAHIQAE CCEEEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VSGRPKHIYSIWRKMRGKELDFSELYDVRAFRVIVPDIKDCYTVLGIVHHLWQPVPKEFD CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHH DYISRPKPNGYKSLHTVVIGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGARGYGGQ HHHCCCCCCCCCCEEEEEECCCCCEEEEEEEHHHHHHHHHCCCHHEEEEHHCCCCCCCCC FSASEKYDEKIAWLRQLLAWKDEIADGGGAEVSGQQAWAQLREATLDDDHIYVLTPQARV CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEE IALPQGATPVDFAYHLHSELGHRCRGARVDGAMVPLNTQLANGQTVEIVAVKEGGPSRDW EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCEEEEEEEECCCCCCCC LNPQLGYLHSSRARQKVRAWFNAVDQQENVAHGRALVEKTLQREGKTSVNLEHLAAKLGF CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC KSPDELFSVVGKEEFSLRNVEQALSDAPAPEPEPEAPANFEKRASGANVAHGASAGVLVV CCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEE GVDALLTQLARCCRPAPPDPISGFVTRGKGMSIHRSDCATFRRMAERAPERVLQTTWSAD EHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC VLGGRGASVYPVDLMIEATDRQGLLRDISEVFAREKMNVIGVKTQSRRNAAFMQFTVEVS CCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECC SASQVQRACTLLGEIQGVVRAARKA CHHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7928955 [H]