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The map label for this gene is rnr [H]

Identifier: 53719487

GI number: 53719487

Start: 2227421

End: 2229955

Strand: Reverse

Name: rnr [H]

Synonym: BPSL1874

Alternate gene names: 53719487

Gene position: 2229955-2227421 (Counterclockwise)

Preceding gene: 53719488

Following gene: 53719486

Centisome position: 54.73

GC content: 67.89

Gene sequence:

>2535_bases
GTGTTAGAATGGGGCGGCATGAGCGGCGCGCCCGTTCGGCTCCGCTTGCCGCGGTCGCGCAAGCCAAACGCAACGAGAAA
AATCATCGACAAGCCCTTGAGCAAGTATCCGTATCCCATCCCGAGCCGCGAAGAGATTCTCGGCGTGCTGCGCACGAGCG
ACGCGCCGCTTGCGGCGAACGACATCGCCGAAGCGCTGTCGATCAAGCGTCAGGAGCGCGAAGGATTTTTCCGGCGCGTC
GCCGCGATGGAGCGCGACGGCCAGATCCGTCTCGACAAGCGCGGTCATTATCAACTGACGCATCCGTCCAACTTCGTCGC
GGGCCGCGTGCAAGGCCACCGCGACGGCTACGGCTTCGTGATTCGCGACGACGGGCAGGATGATCTGTTCCTGCCGAACG
CCGAGATGCAAAAGGTCATGCACAACGACCGCGTGCTGGCGCGGATCGTCGGCTACGATCGGCGCGGCCGGCCGGAAGGG
CACGTCGTCGAGGTGACCGAGCGGGCGAACAAGCGCGTGATCGGGCGCCTCCTGAACGAGAACGGCGCGCTCATCGTCGC
GCCCGAGGACAAGCGGATCAGTCACGACATCCTCGTCACGCAGAACGCGAAGAAGGCGAAGGTCGGGCAGGTCGTCGTCG
TCGAGCTCACCGATTTCCCGAGCCGTCATTCGCAGCCGCTCGGCCGCGTCTGCGAAGTGCTCGGCGATATCGACGATCCC
GGCATGGAGATCGAGATCGCGGTGCGCAAGTACGGCGTGCCGCACGAATTCGGCGCGCAAGCGCTCGGCGAGGCCGCGGC
GCTGCCGGACAAGGTGCGGCCCGCGGATCTGCGCTACCGCGTCGACTTGCGCGACGTGCCGCTCGTCACGATCGACGGCG
AGGACGCGCGCGACTTCGACGACGCCGTGTACTGCGAGCCCGCCGCGGTCGGCCGCGGCGAGGGCTTCCGGCTCATCGTC
GCGATCGCGGACGTGTCGCACTACGTGCAGCCAGGCAGCCCGCTCGACGCCGACGCGGTCGAACGCAGCACGTCGGTCTA
TTTCCCGCGCCGCGTGATTCCGATGCTGCCGGAGAAGCTGTCGAACGGGCTCTGCTCGCTGAATCCGCAGGTCGATCGCT
GCGTGCTCGCGTGCGACATGATCATCAACGCGCGTGGCGACATCAAGGCGTATCAGTTCTATCCGGCCGTGATCCACTCG
GCCGCGCGGCTCACGTACACCGAAGTGGCCGCGGTGCTCTCGAACACGAAGGGGCCGGAGGCCGCGCGCCGCGCCGAGCT
GATGCCGCACCTGCAGCACCTGTACGGCGTCTACAAGGCGCTCTTCGTCGCGCGGCAGAAGCGCGGCGCGATCGACTTCG
ACACGACCGAGACGTACATCGTCTGCAACGCACAGGGCAAGATCGAGCAGATTCTGCCGCGCCAGCGTAACGACGCGCAT
CGGCTGATCGAGGAATGCATGCTTGCCGCGAACGTCTGCGCGGCCGATTTCCTCAAGCGCAACAAGCACCCGGGCCTCTA
CCGCGTGCACGCGGGGCCGACGCCCGAAAAGCTCGAGAATCTGCGCGCGTTCCTGCGCGACATGGGGCTCACGCTGGGCG
GCGGCGACACGCCGCACGCGAGCGATTACGCGGCGCTGATGGCGCACATCCGCGACCGGCCCGACGCGCAGATGCTGCAG
CCGATGCTGCTGCGCTCGATGCAGCAGGCGGTCTACAGTCCGGACAACATCGGCCACTTCGGTCTCGCGTACGACGCGTA
CGCGCACTTCACGAGCCCGATTCGCCGCTATCCCGATCTGCTCACGCACCGCGCGATCTACGCGATCCTGTCCGGCAAGA
AGTACACGCCGAAGTCGCCGGAAGGCGTCGAGCTGAACACCGCGCTGTCGCCGCGCGCGCGCGCGATGCAGCGCGAGGAC
GACGAGGCGCGCGGCCGCGCGCGGTCGAACGCGGCGATCTGGGAGGAGCTCGGGCTGCACTGTTCGTCCAACGAGCGGCG
CGCGGACGAAGCGTCGCGCGACGTCGAGGCATGGCTCAAGTGCTATTTCATGCGCGACAAGCTCGGCGAGGAATACGGCG
GGATGGTGAACGGCGTCACGTCGTTCGGCATCTTCGTGCAGCTCGATGCGCTTTTCATCGAAGGCCTCGTGCATGTGACC
GAGCTCGGCGCCGATTATTTTCAGTACGACGAAGTCAAGAACGAACTGCGCGGCGAGCGCACGGGCATTCGCTACCGGCT
GTCCGACCGCGTGCGCGTGCAGGTGAGCCGCGTCGATCTCGATGCGCGCAAGATCGATTTCCGCCTCGTGCGCGAGACGC
CCGTGAAGGCGCCGCGCCCGGCATCGGCGGTGGCGGCCGAAGCGGGCGCGGGCGGGCCGCGTGTGCGCGCGCTGCCGCCC
GCCGAAGGCGCCGCGCGACGCAAGAAGGCCGCGAGCGCGCCGAGCGCGGCGGTGAAGGAGGCCCGGGCGGCCCGCAAGAA
GGGCGCCGCGTCGAAGCCGGCCGCGAAGAAGGCGCGTTCGCGCAAGAAGTACTGA

Upstream 100 bases:

>100_bases
AGACGGCCAAACGAACCTGTCAACATTTTTTCGAGGGCCGTCCGCATCGCGGCGCGCGCGGCGCAACACGCGGCGTGCGG
CCCGTTCGCCGCAGCGGCGG

Downstream 100 bases:

>100_bases
TCGAGCGCGTCGCCGATCCGGCGGCGCCGACCGAAACGCCGCGCGCCCCGCCAGGGCGCGCGGCGCTTTCCGTTTTCCAT
GCGGCGCGTGCGATGCGCGG

Product: putative ribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MLEWGGMSGAPVRLRLPRSRKPNATRKIIDKPLSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRV
AAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNAEMQKVMHNDRVLARIVGYDRRGRPEG
HVVEVTERANKRVIGRLLNENGALIVAPEDKRISHDILVTQNAKKAKVGQVVVVELTDFPSRHSQPLGRVCEVLGDIDDP
GMEIEIAVRKYGVPHEFGAQALGEAAALPDKVRPADLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPAAVGRGEGFRLIV
AIADVSHYVQPGSPLDADAVERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMIINARGDIKAYQFYPAVIHS
AARLTYTEVAAVLSNTKGPEAARRAELMPHLQHLYGVYKALFVARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAH
RLIEECMLAANVCAADFLKRNKHPGLYRVHAGPTPEKLENLRAFLRDMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQ
PMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKSPEGVELNTALSPRARAMQRED
DEARGRARSNAAIWEELGLHCSSNERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDALFIEGLVHVT
ELGADYFQYDEVKNELRGERTGIRYRLSDRVRVQVSRVDLDARKIDFRLVRETPVKAPRPASAVAAEAGAGGPRVRALPP
AEGAARRKKAASAPSAAVKEARAARKKGAASKPAAKKARSRKKY

Sequences:

>Translated_844_residues
MLEWGGMSGAPVRLRLPRSRKPNATRKIIDKPLSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRV
AAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNAEMQKVMHNDRVLARIVGYDRRGRPEG
HVVEVTERANKRVIGRLLNENGALIVAPEDKRISHDILVTQNAKKAKVGQVVVVELTDFPSRHSQPLGRVCEVLGDIDDP
GMEIEIAVRKYGVPHEFGAQALGEAAALPDKVRPADLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPAAVGRGEGFRLIV
AIADVSHYVQPGSPLDADAVERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMIINARGDIKAYQFYPAVIHS
AARLTYTEVAAVLSNTKGPEAARRAELMPHLQHLYGVYKALFVARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAH
RLIEECMLAANVCAADFLKRNKHPGLYRVHAGPTPEKLENLRAFLRDMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQ
PMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKSPEGVELNTALSPRARAMQRED
DEARGRARSNAAIWEELGLHCSSNERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDALFIEGLVHVT
ELGADYFQYDEVKNELRGERTGIRYRLSDRVRVQVSRVDLDARKIDFRLVRETPVKAPRPASAVAAEAGAGGPRVRALPP
AEGAARRKKAASAPSAAVKEARAARKKGAASKPAAKKARSRKKY
>Mature_844_residues
MLEWGGMSGAPVRLRLPRSRKPNATRKIIDKPLSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRV
AAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNAEMQKVMHNDRVLARIVGYDRRGRPEG
HVVEVTERANKRVIGRLLNENGALIVAPEDKRISHDILVTQNAKKAKVGQVVVVELTDFPSRHSQPLGRVCEVLGDIDDP
GMEIEIAVRKYGVPHEFGAQALGEAAALPDKVRPADLRYRVDLRDVPLVTIDGEDARDFDDAVYCEPAAVGRGEGFRLIV
AIADVSHYVQPGSPLDADAVERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMIINARGDIKAYQFYPAVIHS
AARLTYTEVAAVLSNTKGPEAARRAELMPHLQHLYGVYKALFVARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAH
RLIEECMLAANVCAADFLKRNKHPGLYRVHAGPTPEKLENLRAFLRDMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQ
PMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKSPEGVELNTALSPRARAMQRED
DEARGRARSNAAIWEELGLHCSSNERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDALFIEGLVHVT
ELGADYFQYDEVKNELRGERTGIRYRLSDRVRVQVSRVDLDARKIDFRLVRETPVKAPRPASAVAAEAGAGGPRVRALPP
AEGAARRKKAASAPSAAVKEARAARKKGAASKPAAKKARSRKKY

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=468, Percent_Identity=29.2735042735043, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI190014623, Length=468, Percent_Identity=29.2735042735043, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI134288890, Length=509, Percent_Identity=28.0943025540275, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI19115966, Length=660, Percent_Identity=26.8181818181818, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI219521928, Length=660, Percent_Identity=26.8181818181818, Blast_Score=157, Evalue=5e-38,
Organism=Escherichia coli, GI87082383, Length=757, Percent_Identity=48.3487450462351, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=687, Percent_Identity=27.3653566229985, Blast_Score=199, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI212645896, Length=414, Percent_Identity=29.7101449275362, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17553506, Length=529, Percent_Identity=28.1663516068053, Blast_Score=154, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324552, Length=659, Percent_Identity=25.4931714719272, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24649634, Length=468, Percent_Identity=28.8461538461538, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24654592, Length=437, Percent_Identity=28.8329519450801, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19922976, Length=437, Percent_Identity=28.8329519450801, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24654597, Length=437, Percent_Identity=28.8329519450801, Blast_Score=141, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 93868; Mature: 93868

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEWGGMSGAPVRLRLPRSRKPNATRKIIDKPLSKYPYPIPSREEILGVLRTSDAPLAAN
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHH
DIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGHRDGYGFV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCEEECCCCCCCCEEEE
IRDDGQDDLFLPNAEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNE
EEECCCCCEECCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCC
NGALIVAPEDKRISHDILVTQNAKKAKVGQVVVVELTDFPSRHSQPLGRVCEVLGDIDDP
CCEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCC
GMEIEIAVRKYGVPHEFGAQALGEAAALPDKVRPADLRYRVDLRDVPLVTIDGEDARDFD
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCC
DAVYCEPAAVGRGEGFRLIVAIADVSHYVQPGSPLDADAVERSTSVYFPRRVIPMLPEKL
CCEEECCCCCCCCCCCEEEEEEECHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHCHHHH
SNGLCSLNPQVDRCVLACDMIINARGDIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPE
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHH
AARRAELMPHLQHLYGVYKALFVARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCCHHH
RLIEECMLAANVCAADFLKRNKHPGLYRVHAGPTPEKLENLRAFLRDMGLTLGGGDTPHA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEECCCCCCCC
SDYAALMAHIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSPIRRYPDL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTHRAIYAILSGKKYTPKSPEGVELNTALSPRARAMQREDDEARGRARSNAAIWEELGLH
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHCCCHHHHCCCCCCHHHHHHHCCC
CSSNERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDALFIEGLVHVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHEEHHHHHHHHHHHHH
ELGADYFQYDEVKNELRGERTGIRYRLSDRVRVQVSRVDLDARKIDFRLVRETPVKAPRP
HHCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCHHHHEEEEEECCCCCCCCC
ASAVAAEAGAGGPRVRALPPAEGAARRKKAASAPSAAVKEARAARKKGAASKPAAKKARS
HHHHHHHCCCCCCCEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
RKKY
CCCC
>Mature Secondary Structure
MLEWGGMSGAPVRLRLPRSRKPNATRKIIDKPLSKYPYPIPSREEILGVLRTSDAPLAAN
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHH
DIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGHRDGYGFV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCEEECCCCCCCCEEEE
IRDDGQDDLFLPNAEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNE
EEECCCCCEECCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCC
NGALIVAPEDKRISHDILVTQNAKKAKVGQVVVVELTDFPSRHSQPLGRVCEVLGDIDDP
CCEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCC
GMEIEIAVRKYGVPHEFGAQALGEAAALPDKVRPADLRYRVDLRDVPLVTIDGEDARDFD
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCC
DAVYCEPAAVGRGEGFRLIVAIADVSHYVQPGSPLDADAVERSTSVYFPRRVIPMLPEKL
CCEEECCCCCCCCCCCEEEEEEECHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHCHHHH
SNGLCSLNPQVDRCVLACDMIINARGDIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPE
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHH
AARRAELMPHLQHLYGVYKALFVARQKRGAIDFDTTETYIVCNAQGKIEQILPRQRNDAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCCHHH
RLIEECMLAANVCAADFLKRNKHPGLYRVHAGPTPEKLENLRAFLRDMGLTLGGGDTPHA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEECCCCCCCC
SDYAALMAHIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSPIRRYPDL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTHRAIYAILSGKKYTPKSPEGVELNTALSPRARAMQREDDEARGRARSNAAIWEELGLH
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHCCCHHHHCCCCCCHHHHHHHCCC
CSSNERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDALFIEGLVHVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHEEHHHHHHHHHHHHH
ELGADYFQYDEVKNELRGERTGIRYRLSDRVRVQVSRVDLDARKIDFRLVRETPVKAPRP
HHCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCHHHHEEEEEECCCCCCCCC
ASAVAAEAGAGGPRVRALPPAEGAARRKKAASAPSAAVKEARAARKKGAASKPAAKKARS
HHHHHHHCCCCCCCEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
RKKY
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]