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The map label for this gene is rpiA

Identifier: 53719484

GI number: 53719484

Start: 2224309

End: 2225004

Strand: Reverse

Name: rpiA

Synonym: BPSL1871

Alternate gene names: 53719484

Gene position: 2225004-2224309 (Counterclockwise)

Preceding gene: 53719485

Following gene: 53719483

Centisome position: 54.61

GC content: 68.39

Gene sequence:

>696_bases
ATGACACAAGACGAACTCAAACGCCTCGTCGGCGAGGCCGCTGCCCGATACGTGACCGAAAACGTGCCGCAGGGCGCGGT
GATCGGCGTCGGCACGGGCTCGACCGCCAACTGCTTCATCGATGCGCTCGCGGCCGTCAAGGATCGCTATCGCGGCGCGG
TGTCGAGTTCGGTGGCGACGACCGAGCGCCTGAAGTCACACGGCATCAAGGTGTTCGATCTGAACGAGATCGAATCGCTG
CAGGTGTATGTCGACGGCGCCGACGAGATCGACGGGAGCGGCGCGATGATCAAGGGCGGCGGCGGCGCGCTCACGCGCGA
GAAGATCGTTGCTTCGGTCGCCGAAACGTTCGTGTGCATCGCCGATGCGAGCAAGCGCGTGGCGGTGCTCGGCCAGTTCC
CGCTGCCCGTCGAGGTGGTGCCGATGGCGCGCACCGCGATCGGCCGCCGGCTCGCCGCGCTGGGCGGCGTGCCCGTGCTG
CGCGTGAAGCAGGACGGCGCGCCGTACGTGACCGACAACGGCAACGAGATTCTCGACGTGAAGGGCCTGCGGATCGACGA
TCCGCGCGCGCTCGAAGCGGCGATCAACGGCTGGCCCGGCGTCGTGACGGTCGGGCTGTTCGCGCAACGCGGCGCGGATC
TCTGCCTGCTCGGCACCGAGCGCGGCGTCGAGACGCTCCGTTACGCTGCGCATTAA

Upstream 100 bases:

>100_bases
GCGATGCGGCGGCGCGCCGCCGGCGCGACGAAAATATCCGTCGGACGAAGCGTCTCCGGTAAACTCGTGCTTTTCGCACT
TCGATTGCTTGACGCTTCCC

Downstream 100 bases:

>100_bases
ATAAATCATTCAAGAATGAATTCGGTGTGCTAAAGCAATAAAGTCGGTTAATTCCAATCATAAAAAATTGATTGCCGACG
CATTCGCGCACCATCCGATC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESL
QVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVL
RVKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH

Sequences:

>Translated_231_residues
MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESL
QVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVL
RVKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
>Mature_230_residues
TQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIKVFDLNEIESLQ
VYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCIADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLR
VKQDGAPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=235, Percent_Identity=36.5957446808511, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1789280, Length=226, Percent_Identity=64.6017699115044, Blast_Score=276, Evalue=8e-76,
Organism=Caenorhabditis elegans, GI17551758, Length=215, Percent_Identity=38.6046511627907, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=230, Percent_Identity=29.5652173913043, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281364072, Length=222, Percent_Identity=35.5855855855856, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_BURM7 (A3MJY8)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001080574.1
- ProteinModelPortal:   A3MJY8
- SMR:   A3MJY8
- GeneID:   4894420
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_1017
- TIGR:   BMA10247_1017
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- BioCyc:   BMAL320389:BMA10247_1017-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24203; Mature: 24072

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVAT
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TERLKSHGIKVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCI
HHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHEEEE
ADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGAPYVTDNGNEILDV
ECCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCEEEEE
KGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
CCCEECCCHHHHHHHCCCCCHHEEHHHHHCCCCEEEEECCCCHHHHHHHCC
>Mature Secondary Structure 
TQDELKRLVGEAAARYVTENVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVAT
CHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TERLKSHGIKVFDLNEIESLQVYVDGADEIDGSGAMIKGGGGALTREKIVASVAETFVCI
HHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHEEEE
ADASKRVAVLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGAPYVTDNGNEILDV
ECCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCEEEEE
KGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTERGVETLRYAAH
CCCEECCCHHHHHHHCCCCCHHEEHHHHHCCCCEEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA