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The map label for this gene is dgoR [H]

Identifier: 53719483

GI number: 53719483

Start: 2223258

End: 2223971

Strand: Reverse

Name: dgoR [H]

Synonym: BPSL1870

Alternate gene names: 53719483

Gene position: 2223971-2223258 (Counterclockwise)

Preceding gene: 53719484

Following gene: 53719482

Centisome position: 54.58

GC content: 64.85

Gene sequence:

>714_bases
ATGGAGCAGGGAAAAGACCGGTCACTGGTCAGTAAAGTGATGGATGGGCTTGTCACGGGAATCGTCGAGGACAAGTATGG
CGGCGTGCTGCCGCCGCAGGACGTGCTGTCGAAGGAGTTCGACGTGAGCCGCACCGTGATGCGCGAAGCGCTCTCGATGT
TGCTGGCGCGCGACATGCTCGACGTGCGTCCGAAGGTCGGCACGCGCGTGCGGCCGATGAGCCACTGGAGGATGATCGAC
GAAGACGTCGTGAACTGGCGTTTCCGGGCGAAGCCCGATCGGCAGTTCATTCGCGACGTGATCGAATTCCGGACGCTGAT
CGAGCCGCGTGCGACCGCGCAGGCGGCGAGTCGCGCAACGACGGCGGAAATCGCCGGGATCAGGGAGGCATACGAGCTGT
TCAAACTGGCCGAGCCGGGAACACCGGCTTACGACGAGGCGGATGAGCTGCTGCATACGCGGATCGTGCATGCGAGCGGC
AATCAGTTCTTCCAGCAGATGGCGGCGATCATTCGCGGCGCGCTGCGTGTCGTCAATCCGCGGATGAGCCAGCGCGACGA
TATTCGCGCGCTCGCGCTCAAATCGCACGGGCGCGTCGTCGACGCGATCGAGCGACGCGACGCGCGCGACGCGGAGGCGG
CCGCGCTCGAGCTGATCGATTACACGGCGGAGGAGATGCGCGACTTCGCGGTCGACATGCCCGAACGCAACTGA

Upstream 100 bases:

>100_bases
CATAAGAACAAAGGCTGATAGTCGTGTCATTTCGATACAGAGGGCCGGCGAGACTGCGAGGGCATTGTGCCAACACAGGT
GATGTTCGGGGAGAGGTCTC

Downstream 100 bases:

>100_bases
GCGCCATGCGTGTCGCGCGCCGCGGGCCGGCCGTTATCATGACGGCCGGCCGGGCGCGAGCCCGGTGCCGGCCTCTTTCT
GCGACACGGAATGGATTCAA

Product: GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEQGKDRSLVSKVMDGLVTGIVEDKYGGVLPPQDVLSKEFDVSRTVMREALSMLLARDMLDVRPKVGTRVRPMSHWRMID
EDVVNWRFRAKPDRQFIRDVIEFRTLIEPRATAQAASRATTAEIAGIREAYELFKLAEPGTPAYDEADELLHTRIVHASG
NQFFQQMAAIIRGALRVVNPRMSQRDDIRALALKSHGRVVDAIERRDARDAEAAALELIDYTAEEMRDFAVDMPERN

Sequences:

>Translated_237_residues
MEQGKDRSLVSKVMDGLVTGIVEDKYGGVLPPQDVLSKEFDVSRTVMREALSMLLARDMLDVRPKVGTRVRPMSHWRMID
EDVVNWRFRAKPDRQFIRDVIEFRTLIEPRATAQAASRATTAEIAGIREAYELFKLAEPGTPAYDEADELLHTRIVHASG
NQFFQQMAAIIRGALRVVNPRMSQRDDIRALALKSHGRVVDAIERRDARDAEAAALELIDYTAEEMRDFAVDMPERN
>Mature_237_residues
MEQGKDRSLVSKVMDGLVTGIVEDKYGGVLPPQDVLSKEFDVSRTVMREALSMLLARDMLDVRPKVGTRVRPMSHWRMID
EDVVNWRFRAKPDRQFIRDVIEFRTLIEPRATAQAASRATTAEIAGIREAYELFKLAEPGTPAYDEADELLHTRIVHASG
NQFFQQMAAIIRGALRVVNPRMSQRDDIRALALKSHGRVVDAIERRDARDAEAAALELIDYTAEEMRDFAVDMPERN

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=221, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI48994961, Length=225, Percent_Identity=27.5555555555556, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26924; Mature: 26924

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQGKDRSLVSKVMDGLVTGIVEDKYGGVLPPQDVLSKEFDVSRTVMREALSMLLARDML
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRPKVGTRVRPMSHWRMIDEDVVNWRFRAKPDRQFIRDVIEFRTLIEPRATAQAASRAT
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TAEIAGIREAYELFKLAEPGTPAYDEADELLHTRIVHASGNQFFQQMAAIIRGALRVVNP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
RMSQRDDIRALALKSHGRVVDAIERRDARDAEAAALELIDYTAEEMRDFAVDMPERN
CCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEQGKDRSLVSKVMDGLVTGIVEDKYGGVLPPQDVLSKEFDVSRTVMREALSMLLARDML
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRPKVGTRVRPMSHWRMIDEDVVNWRFRAKPDRQFIRDVIEFRTLIEPRATAQAASRAT
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TAEIAGIREAYELFKLAEPGTPAYDEADELLHTRIVHASGNQFFQQMAAIIRGALRVVNP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
RMSQRDDIRALALKSHGRVVDAIERRDARDAEAAALELIDYTAEEMRDFAVDMPERN
CCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]