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The map label for this gene is blh [H]

Identifier: 53719195

GI number: 53719195

Start: 1811369

End: 1812292

Strand: Reverse

Name: blh [H]

Synonym: BPSL1561

Alternate gene names: 53719195

Gene position: 1812292-1811369 (Counterclockwise)

Preceding gene: 53719199

Following gene: 53719194

Centisome position: 44.48

GC content: 69.26

Gene sequence:

>924_bases
ATGGGCTCCAGGAGAAACCTCGTGACAACAGCGTCCACGATGACGGTCGAAGGCTTTTTCGACCCGGCGACATGCACGAT
CAGCTATTTGCTGTTCGATTCCGGCAGCGGCGAATGCGCGCTGATCGACAGCGTGCTCGACTACGACCCGAAATCCGGCC
GCACGCGCACCGCGAGCGCGGACCAGTTGATCGCGCGCGTCGCGGCGCTCGGCGCGCGCGTGCGCTGGCTGCTCGAGACG
CACGTGCACGCCGACCATCTGTCGGCCGCGCCGTACCTGAAAACGCGGGTCGGCGGCGAGATCGCGATCGGCCGCCACGT
GACGCGCGTGCAGGACGTGTTCGGCAAGCTGTTCAACGCAGGCCCCGCGTTCGCGCACGACGGCAGCCAGTTCGACCGCC
TGCTCGACGACGGCGACACGCTCGCGCTCGGCGCGCTCTCGATCCGCGCGATGCATACGCCGGGCCACACGCCGGCGTGC
ATGACCTACGTCGTCACCGAAGCGCATGCGGCGCACGACGCGCGCGACGCGGCCGCGTTCGTCGGCGATACGCTGTTCAT
GCCCGACTACGGCACCGCGCGCTGCGACTTCCCCGGCGGCGACGCGCGCTCGCTGTACCGGTCGATCCGCAAGGTGCTGA
GCCTGCCGCCCGCGACGCGCCTGTACATGTGCCACGACTATCAGCCGAACGGCCGCGCGATCCAGTACGCGAGCACCGTC
GCCGACGAGTTGCGCGAGAACGTGCACATCCGCGAAGGCGTCACCGAGGACGATTTCGTCGCGATGCGCACCGCGCGCGA
CGCGACGCTCGACATGCCGGTGCTGATGCTGCCCTCGGTGCAGGTCAACATGCGCGCGGGCCGCCTGCCCGAGCCCGAGG
ACAACGGCGTGCGCTACCTGAAGATCCCGCTCGACGCGATCTGA

Upstream 100 bases:

>100_bases
GGAGGAACAAAACACGATTTGAATCAAGTACCTGTGCTCGCCGATCGGCAATGCTGTCAACTTGGCACGGTTCTTGTTCG
AATGAACGCCATCTCGACGA

Downstream 100 bases:

>100_bases
GCCCGCGGCCCGCCTTCCCCAACGACGCACGACATACGACCACGCCCATCATGGAAATCCGCAAGCTGACCGACACGCTA
TCGGTCTCCCCCCAGCTCGT

Product: putative metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MGSRRNLVTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLET
HVHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPAC
MTYVVTEAHAAHDARDAAAFVGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTV
ADELRENVHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI

Sequences:

>Translated_307_residues
MGSRRNLVTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLET
HVHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPAC
MTYVVTEAHAAHDARDAAAFVGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTV
ADELRENVHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
>Mature_306_residues
GSRRNLVTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETH
VHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNAGPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACM
TYVVTEAHAAHDARDAAAFVGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTVA
DELRENVHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=289, Percent_Identity=30.1038062283737, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17538952, Length=266, Percent_Identity=29.6992481203008, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221330176, Length=277, Percent_Identity=29.2418772563177, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33467; Mature: 33336

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRRNLVTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASA
CCCCCCEEEEECEEEEECCCCCHHEEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCH
DQLIARVAALGARVRWLLETHVHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNA
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHCC
GPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEAHAAHDARDAAAF
CCCCCCCCHHHHHHHCCCCEEEEEEEEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHH
VGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTV
HCCEEECCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHH
ADELRENVHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYL
HHHHHHCCCHHCCCCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEE
KIPLDAI
EEECCCC
>Mature Secondary Structure 
GSRRNLVTTASTMTVEGFFDPATCTISYLLFDSGSGECALIDSVLDYDPKSGRTRTASA
CCCCCEEEEECEEEEECCCCCHHEEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCH
DQLIARVAALGARVRWLLETHVHADHLSAAPYLKTRVGGEIAIGRHVTRVQDVFGKLFNA
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHCC
GPAFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEAHAAHDARDAAAF
CCCCCCCCHHHHHHHCCCCEEEEEEEEEEEEECCCCCCHHHHEEHHHHHHHHHHHHHHHH
VGDTLFMPDYGTARCDFPGGDARSLYRSIRKVLSLPPATRLYMCHDYQPNGRAIQYASTV
HCCEEECCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHH
ADELRENVHIREGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYL
HHHHHHCCCHHCCCCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEE
KIPLDAI
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]