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The map label for this gene is argF [H]

Identifier: 53718508

GI number: 53718508

Start: 1009176

End: 1010105

Strand: Reverse

Name: argF [H]

Synonym: BPSL0869

Alternate gene names: 53718508

Gene position: 1010105-1009176 (Counterclockwise)

Preceding gene: 53718510

Following gene: 53718506

Centisome position: 24.79

GC content: 63.87

Gene sequence:

>930_bases
ATGACCGCCAAAACCATTCGTCACTACCTGCAGTTCAAGGATTTCTCGCTGGAAGACTACGAGTACGTGCTCGAACGCAC
GGGTATCCTGAAGCGCAAATTCAAGAACTACGAGACCTATCACCCGCTGCACGACCGCACGCTCGCGATGATCTTCGAGA
AGAGCTCGACGCGCACGCGCCTGTCGTTCGAGGCCGGGATCTTCCAGCTGGGCGGCCACGCCGTGTTCATGAGCACGCGC
GACACGCAGCTCGGTCGCGGCGAGCCCGTCGAGGATTCGGCGCAGGTGATCTCGCGAATGGTCGACATCATCATGATCCG
CACGTTCGAGCAGGACATCATCCAGCGCTTCGCCGAGAATTCGCGCGTGCCGGTGATCAACGGCCTGACGAACGAGTACC
ACCCGTGCCAGGTGCTCGCCGACATCTTCACGTATTACGAGCACCGCGGCCCGATTCGCGGCAAGACGGTCGCCTGGGTC
GGCGACGCGAACAACATGCTGTACACCTGGATCCAGGCCGCGCGCATCCTCGGCTTCAAGCTGCGGCTGTCAACGCCCCC
CGGCTACGCGCTCGACACGAAGCTCGTCGACGCGGAAAGCGCGCCGTTCTACCAGGTGTTCGACGATCCGAACGAAGCGT
GCAAGGGCGCGGACCTCGTCACGACCGACGTGTGGACGAGCATGGGCTTCGAGGCGGAGAACGAGGCGCGCAAGCAGGCG
TTCGCCGACTGGTGCGTCGACGAGGAGATGATGTCGCACGCGCACCCCGATGCGCTCTTCATGCATTGCCTGCCCGCGCA
CCGCGGCGAGGAAGTGACGGCGGGCGTGATCGACGGCCCGCAGAGCGTCGTGTGGGACGAAGCGGAGAACCGCCTGCACG
TGCAGAAGGCGCTGATGGAGTTCCTGCTGCTCGGACGCCTGAACCACTGA

Upstream 100 bases:

>100_bases
CAAAGCGTAAAAAATCCTTTATGCTGGTTCGAGTTATCACATCCGACGGCGGCGCCGTCCGGCGCGTCCGCCGCCGGTTG
AGTCCGCCGTATTTCGTTTC

Downstream 100 bases:

>100_bases
CCCACTGACGCGCCGTCGCGCGCGCCCGCACGCCGCGGGCCGCGAGGTGCGGGCGCGCCGGCCGTGCAACGAAGCGCCCT
CGCCCTCGCCCTCGCCTGCG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWV
GDANNMLYTWIQAARILGFKLRLSTPPGYALDTKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
FADWCVDEEMMSHAHPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH

Sequences:

>Translated_309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWV
GDANNMLYTWIQAARILGFKLRLSTPPGYALDTKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
FADWCVDEEMMSHAHPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH
>Mature_308_residues
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRD
TQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVG
DANNMLYTWIQAARILGFKLRLSTPPGYALDTKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQAF
ADWCVDEEMMSHAHPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=40.4605263157895, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI18105007, Length=305, Percent_Identity=25.5737704918033, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=36, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1786469, Length=326, Percent_Identity=36.1963190184049, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI2367364, Length=308, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=297, Percent_Identity=26.9360269360269, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=33.5365853658537, Blast_Score=195, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6322331, Length=304, Percent_Identity=25, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24642586, Length=311, Percent_Identity=26.3665594855305, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35419; Mature: 35287

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAEN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVGDANNMLYTWIQAARILGFK
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
LRLSTPPGYALDTKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
EEECCCCCCEECCEEECCCCCCEEEEECCHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHH
FADWCVDEEMMSHAHPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHCCCHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLNH
HHHHHCCCC
>Mature Secondary Structure 
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAEN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVGDANNMLYTWIQAARILGFK
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
LRLSTPPGYALDTKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKQA
EEECCCCCCEECCEEECCCCCCEEEEECCHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHH
FADWCVDEEMMSHAHPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHCCCHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLNH
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA